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Characteristics of the imaging diagnosis of alveolar echinococcosis

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World Journal of Gastrointestinal Surgery 2024年第9期16卷 2748-2754页

作者： Sonay Aydin Baris Irgul Kemal Bugra memis Volkan Kızılgoz mecit Kantarci Department of Radiology Erzincan Binali Yıldırım UniversityFaculty of MedicineErzincan 24100Türkiye Department of Radiology Erzurum Ataturk UniversityErzurum 25000Türkiye

Alveolar echinococcosis(AE)primarily manifests in the liver and exhibits charac-teristics resembling those of slow-growing malignant *** Echino-coccus multilocularis infection can be *** infiltrating the vascular systems,biliary tracts,and the hilum of the liver,it might lead to various *** to its ability to infiltrate neighbouring tissues or metastasize to distant organs,AE can often be mistaken for *** present a concise overview of the epi-demiological and pathophysiological characteristics of AE,as well as the clinical manifestations of the *** article primarily examines the imaging charac-teristics of AE using various imaging techniques such as ultrasonography,com-puted tomography(CT),magnetic resonance imaging,diffusion-weighted ima-ging,and virtual non-enhanced dual-energy *** additionally examined the contribution of radiography in the diagnosis,treatment,and monitoring of the condition.

关键词： Alveolar echinococcosis Echinococcus multilocularis Virtual non-enhanced dual-energy computed tomography Percutaneous cyst drainage Cyst infection Interven-tional radiology

Empirical model for fusion cross sections of Ca-induced reactions

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Chinese Physics C 2024年第3期48卷 126-132页

作者： Reddi Rani.L N.Sowmya K.N Sridhar H C.manjunatha m.m.Armstrong Arasu Department of Physics St.Joseph's College(Autonomous)Affiliated to Bharathidasan UniversityTiruchirappalli620002TNIndia Department of Physics Govt.First.Grade CollegeChikkaballapur-562101KarnatakaIndia Department of Physics Govt.First.Grade CollegeMalur-563160KarnatakaIndia Department of Physics Govt.First.Grade CollegeDevanahalli-562110KarnatakaIndia

A new empirical formula for the astrophysical S-factor has been suggested as a function of the Coulomb interaction parameter,center of mass energy,and barrier *** 22 fusion reactions with ^(40,48)Ca as projectiles were considered for different targets,leading to compound nuclei with atomic and mass numbers varying between 40≤z≤≤z≤112 and 88≤A≤27888≤A≤278,*** fusion cross-sections have been estimated using the geometric factor,the Gamow-Sommerfield factor,and the empirical formula for the *** study's findings showed better agreement with those of available experiments when compared to Wong's *** present work leads to a smaller standard deviation value than Wong's formula when used to correlate the experimental data of calcium-induced fusion ***'s formula provides a good approximation of fusion cross-sections when the center of mass energy is below the fusion barrier when compared to above the fusion barrier.

关键词： fusion cross-sections Wong formula Gamow-Sommerfield-factor Geometric-factor S-factor

Topology-Optimized 4D Printing of a Soft Actuator

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Acta mechanica Solida Sinica 2020年第3期33卷 418-430页

作者： Ali zolfagharian martin Denk mahdi Bodaghi Abbas z.Kouzani Akif Kaynak School of Engineering Deakin UniversityGeelong 3216Australia munich University of Applied Sciences 80335 MunichGermany Department of Engineering School of Science and TechnologyNottingham Trent UniversityNottingham NG 118NSUK

Soft robots and actuators are emerging devices providing more capabilities in the field of *** flexibility and compliance attributing to soft functional materials used in the fabrication of these devices make them ideal for delivering delicate tasks in fragile environments,such as food and biomedical ***,the intuitive nonlinearity of soft functional materials and their anisotropic actuation in compliant mechanisms constitute an existent challenge in improving their *** optimization(TO)along with four-dimensional(4D)printing is a powerful digital tool that can be used to obtain optimal internal architectures for the efficient performance of porous soft *** paper employs TO analysis for achieving high bending deflection of a 3D printed polyelectrolyte actuator,which shows bending deformations in response to electrical stimuli in an electrolyte *** performance of the actuator is studied in terms of maximum bending and actuation rate compared with a solid,uniformly 3D printed and topology-optimized *** experimental results proved the effectiveness of TO on achieving higher bending deformation and actuation rate against a uniformly 3D printed actuator.

关键词： Topology optimization 4D printing 3D printing Soft actuator

Correlation Between Local Atomic Symmetry and mechanical Properties in metallic Glasses

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Journal of materials Science & Technology 2014年第6期30卷 551-559页

作者： m.z.Li Department of Physics Renmin University of China Beijing Key Laboratory of Opto-Electronic Functional materials & micro-nano Devices Renmin University of China

The local atomic symmetry was investigated and discussed for understanding mechanical, vibrational and dynamical properties in metallic glasses. Local five-fold symmetry was defined based on the ratio of pentagons to the total number of faces in a Voronoi cluster analyzed by Voronoi tessellation method. It is found that the plastic deformation prefer to be initiated in the regions with less degree of local five-fold symmetry （LFFS） and propagate gradually toward the region with more degree of LFFS. On the other hand, the local structures having less degree of LFFS contribute more to the soft low-frequency modes, and thus the so-called boson peak, while those with more degree of LFFS participate more in moderate- and high- frequency modes in metallic glasses. The relationship between local atomic symmetry and structural heterogeneity, mechanical heterogeneity, and glass transition was also discussed. It is shown that local atomic symmetry could be a general structural indicator in metallic liquids and glasses for better understanding the structure-property relationship in amorphous alloys.

关键词： metallic glasses Atomic symmetry Deformation molecular dynamics

Exercise training improves long-term memory in obese mice

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Life metabolism 2024年第1期3卷 37-50页

作者： Oliver K.Fuller Casey L.Egan Tina L.Robinson Nimna Perera Heidy K.Latchman Lauren V.Terry Emma D.mcLennan Carolina Chavez Emma L.Burrows John W.Scott Robyn m.murphy Henriette van Praag martin Whitham mark A.Febbraio monash Institute of Pharmaceutical Sciences Monash UniversityMelbourneVictoria3052Australia La Trobe Institute for molecular Science La Trobe UniversityMelbourneVictoria3086Australia Florey Institute of Neuroscience and mental Health University of MelbourneMelbourneVictoria3052Australia Department of Biomedical Sciences Charles E.Schmidt College of Medicineand Stiles-Nicholson Brain InstituteFlorida Atlantic UniversityJupiterFL 33458United States College of Life and Environmental Sciences University of BirminghamEdgbastonBirmingham B152TTUnited Kingdom

Obesity has been linked to a range of pathologies,including *** contrast,regular physical activity is associated with the prevention or reduced progression of ***,physical activity can improve memory and spatial cognition,reduce age-related cognitive decline,and preserve brain volume,but the mechanisms are not fully ***,we investigated whether any detrimental effects of high-fat diet(HFD)-induced obesity on cognition,motor behavior,adult hippocampal neurogenesis,and brain-derived neurotrophic factor(BDNF)could be mitigated by voluntary exercise training in male C57Bl/6 ***-induced impairment of motor function was not reversed by ***,voluntary wheel running improved long-term memory and increased hippocampal neurogenesis,suggesting that regular physical activity may prevent cognitive decline in obesity.

关键词： obesity exercise cognition

TmB相关免疫浸润调控评分(mOTIF)预测免疫治疗响应并指导联合增效

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Science Bulletin 2024年第6期69卷 803-822页

作者：钱政宇潘艺芊李薛鑫陈衍行吴灏祥刘泽先 martin Kosar Jiri Bartek 王梓贤徐瑞华 Department of medical Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangdong Provincial Clinical Research Center for CancerResearch Unit of Precision Diagnosis and Treatment for Gastrointestinal CancerChinese Academy of Medical SciencesGuangzhou 510060China Science for Life Laboratory Division of Genome BiologyDepartment of Medical Biochemistry and BiophysicsKarolinska InstituteStockholm S-17121Sweden Department of General Surgery The Fourth Affiliated HospitalChina Medical UniversityShenyang 110032China Bioinformatics Platform Sun Yat-sen University Cancer CenterGuangzhou 510060China zhejiang University-University of Edinburgh Institute Zhejiang University School of MedicineHaining 314400China Edinburgh medical School Biomedical SciencesCollege of Medicine and Veterinary MedicineThe University of EdinburghEdinburgh EH11LTUK Danish Cancer Society Research Center Copenhagen DK-2100Denmark Laboratory of Artificial Intelligence and Data Science Sun Yat-sen University Cancer CenterGuangzhou 510060China

Patients with high tumor mutational burden(TmB)levels do not consistently respond to immune checkpoint inhibitors(ICIs),possibly because a high TmB level does not necessarily result in adequate infiltration of CD8^(+)T *** bulk ribonucleic acid sequencing(RNA-seq)data from 9311 tumor samples across 30 cancer types,we developed a novel tool called the modulator of TmB-associated immune infiltration(mOTIF),which comprises genes that can determine the extent of CD8^(+)T cell infiltration prompted by a certain TmB *** confirmed that mOTIF can accurately reflect the integrity and defects of the cancer-immunity *** analyzing 84 human single-cell RNA-seq datasets from 32 types of solid tumors,we revealed that mOTIF can provide insights into the diverse roles of various cell types in the modulation of CD8^(+)T cell *** pretreatment RNA-seq data from 13 ICI-treated cohorts,we validated the use of mOTIF in predicting CD8^(+)T cell infiltration and ICI *** the components of mOTIF,we identified EmC3 as a negative regulator of CD8^(+)T cell infiltration,which was validated via in vivo ***,mOTIF provided guidance for the potential combinations of programmed death 1 blockade with certain immunostimulatory drugs to facilitate CD8^(+)T cell infiltration and improve ICI efficacy.

关键词： Tumor mutational burden Immunotherapy Cancer-immunity cycle Treatment efficacy prediction CD8^(+)T cell infiltration Combination therapy

The Effect of Non-Contact Conditions in a Splinted Fixed Partial Denture on the Load Sharing mechanism： A Finite Element Study

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Journal of Bionic Engineering 2012年第3期9卷 336-342页

作者： m. z. Bendjaballah Biomedical Technology Department College of Applied Medical Sciences King Saud University Riyadh Saudi Arabia

A computer-aided design model for a fixed partial denture was constructed and used in a finite element analysis to study the overall load sharing mechanism between the fixed partial denture and oral structures while the denture base rested on the al- veolar ridge. To investigate the consequences of non-contact conditions, three additional models were generated incorporating a uniform clearance of 0.125 mm, 0.25 mm, and 0.5 mm, respectively. A 100 N static load located at the free end of the prosthesis was applied while the distal portion of the jaw was set fixed. The results show that whilst releasing the ridge almost entirely, the presence of the clearance drastically increased the load on the splinting teeth. A pull-out force on the canine tooth of about 44 N was computed, accompanied by a mesio-distal moment of about 500 ***. The combination of which was similar to the tooth extraction maneuver performed by the dentist. In contrast, the second premolar was found to bear a push-in force of almost 115 N. The first molar, though barely solicited in the contact condition, became substantially loaded in non-contact conditions, which validates the choice of sacrificing three teeth to support the denture.

关键词： finite element analysis splinted fixed partial denture hygienic space load transfer mechanism contact problem

Long-term trends in the abundance and breeding performance in Adélie penguins:the Argentine Ecosystem monitoring Program

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Advances in Polar Science 2024年第1期35卷 132-140页

作者： mariana A.JUÁRES Anahím.SILVESTRO Brenda C.ALFONSO m.mercedes SANTOS Departamento Biología de Predadores Tope Instituto Antártico Argentino(IAA)Buenos Aires B1650CSPArgentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET) Buenos Aires C1425FQBArgentina Laboratorios Anexos Facultad de Ciencias Naturales y MuseoUniversidad Nacional de La PlataLa Plata B1904AMAArgentina INEDES(CONICET-UNLu) Buenos Aires C1425FQBArgentina Facultad de Ciencias Naturales y museo Universidad Nacional de La PlataLa Plata B1900FWAArgentina Instituto Antártico Argentino(IAA) Buenos Aires B1650CSPArgentina

In this work,we report long-term trends in the abundance and breeding performance of Adélie penguins(Pygoscelis adeliae)nesting in three Antarctic colonies(i.e.,at martin Point,South Orkneys Islands;Stranger Point/Cabo Funes,South Shetland Islands;and Esperanza/Hope Bay in the Antarctic Peninsula)from 1995/96 to 2022/*** yearly count data of breeding groups selected,we observed a decline in the number of breeding pairs and chicks in crèche at all colonies ***,the magnitude of change was higher at Stranger Point than that in the remaining ***,the index of breeding success,which was calculated as the ratio of chicks in crèche to breeding pairs,exhibited no apparent trend throughout the study ***,it displayed greater variability at martin Point compared to the other two colonies under *** the number of chicks in crèche of Adélie penguins showed a declining pattern,the average breeding performance was similar to that reported in gentoo penguin colonies,specifically,those undergoing a population increase(even in sympatric colonies facing similar local conditions).Consequently,it is plausible to assume a reduction of the over-winter survival as a likely cause of the declining trend observed,at least in the Stranger Point and Esperanza ***,we cannot rule out local effects during the breeding season affecting the Adélie population of martin Point.

关键词： long-term monitoring Adélie penguin breeding pairs chicks crèched breeding success population trends

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Fire hazard in transportation infrastructure:Review,assessment,and mitigation strategies

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Frontiers of Structural and Civil Engineering 2021年第1期15卷 46-60页

作者： Venkatesh KODUR m.z.NASER Department of Civil and Environmental Engineering Michigan State UniversityEast LansingMI 48824-1226USA Glenn Department of Civil Engineering Clemson UniversityClemsonSC 29634USA

This paper reviews the fire problem in critical transportation infrastructures such as bridges and *** magnitude of the fire problem is illustrated,and the recent increase in fire problems in bridges and tunnels is *** research undertaken to address fire problems in transportation structures is reviewed,as well as critical factors governing the performance of those ***,key strategies recommended for mitigating fire hazards in bridges and tunnels are presented,and their applicability to practical situations is demonstrated through a practical case ***,research needs and emerging trends for enhancing the“state-of-the-art”in this area are discussed.

关键词： fire hazard bridges tunnels fire resistance mitigation strategies transportation infrastructure