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millimetric devices for nerve stimulation:a promising path towards miniaturization

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Neural Regeneration Research 2024年第8期19卷 1702-1706页

作者： Ryan m.Dorrian Anna V.leonard Antonio Lauto Spinal Cord Injury Research Group School of BiomedicineThe University of AdelaideAdelaideSAAustralia School of Science Western Sydney UniversityPenrithNSWAustralia

Nerve stimulation is a rapidly developing field,demonstrating positive outcomes across several *** potential benefits,current nerve stimulation devices are large,complicated,and are powered via implanted pulse *** facto rs necessitate invasive surgical implantation and limit potential *** nerve stimulation devices to millimetric sizes would make these interventions less invasive and facilitate broader therapeutic ***,device miniaturization presents a serious engineering *** review presents significant advancements from several groups that have overcome this challenge and developed millimetricsized nerve stimulation *** are based on antennas,mini-coils,magneto-electric and optoelectronic materials,or receive ultrasound *** highlight key design elements,findings from pilot studies,and present several considerations for future applications of these devices.

关键词： biomedical engineering deep brain stimulation electrical engineering electrical stimulation neuromodulation peripheral nerve stimulation

Understanding the catalysis of chromium trioxide added magnesium hydride for hydrogen storage and Li ion battery applications

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Journal of magnesium and Alloys 2024年第3期12卷 1117-1130页

作者： D.Pukazhselvan IhsanÇaha Catarina de Lemos Sergey m.mikhalev Francis leonard Deepak Duncan Paul Fagg Department of mechanical Engineering TEMA-Centre for Mechanical Technology and AutomationUniversity of AveiroAveiro 3810-193Portugal LASI-Intelligent Systems Associate Laboratory Guimarães 4800-058Portugal Nanostructured materials Group International Iberian Nanotechnology Laboratory(INL)Avenida Mestre Jose VeigaBraga 4715-330Portugal

This study explores how the chemical interaction between magnesium hydride(mgH_(2))and the additive CrO_(3) influences the hydrogen/lithium storage characteristics of mgH_(2).We have observed that a 5 wt.%CrO_(3) additive reduces the dehydrogenation activation energy of mgH_(2) by 68 kJ/mol and lowers the required dehydrogenation temperature by 80℃.CrO_(3) added mgH_(2) was also tested as an anode in an Li ion battery,and it is possible to deliver over 90%of the total theoretical capacity(2038 mAh/g).Evidence for improved reversibility in the battery reaction is found only after the incorporation of additives with mgH_(2).In depth characterization study by X-ray diffraction(XRD)technique provides convincing evidence that the CrO_(3) additive interacts with mgH_(2) and produces Cr/mgO *** free energy analyses confirm the thermodynamic feasibility of conversion from mgH_(2)/CrO_(3) to mgO/Cr,which is well supported by the identification of Cr(0)in the powder by X ray photoelectron spectroscopy(XPS)*** high resolution transmission electron microscopy(HRTEm)and energy dispersive spectroscopy(EDS)we found evidence for the presence of 5 nm size Cr nanocrystals on the surface of mgO rock salt *** is also convincing ground to consider that mgO rock salt accommodates Cr in the *** observations support the argument that creation of active metal–metal dissolved rock salt oxide interface may be vital for improving the reactivity of mgH_(2),both for the improved storage of hydrogen and lithium.

关键词： Hydrogen storage Rechargeable batteries Binary hydrides metal oxides Catalytic mechanism.

Demonstrating grating-based phase-contrast imaging of laser-driven shock waves

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matter and Radiation at Extremes 2024年第4期9卷 90-97页

作者： leonard Wegert Stephan Schreiner Constantin Rauch Bruno Albertazzi Paulina Bleuel Eric Frojdh michel Koenig Veronika Ludwig Artem Smartynenko Pascal meyer Aldo mozzanica michael müller Paul Neumayer markus Schneider Angelos Triantafyllidis Bernhard Zielbauer Gisela Anton Thilo michel Stefan Funk Plasma Physics Department GSI Helmholtzzentrum fur SchwerionenforschungPlanckstraBe 164291 DarmstadtGermany Erlangen Centre for Astroparticle Physics(ECAP) Friedrich-Alexander-Universität Erlangen-NurnbergNikolaus-Fiebiger-StraBe 291058 ErlangenGermany LULI-CNRS CEASorbonne UniversitésEcole PolytechniqueInstitut Polytechnique de ParisF-91120 Palaiseau CedexFrance Paul Scherrer Institut(Psi) Forschungsstrasse 1115232VilligenSwitzerland Karlsruhe Institute of Technology Institute of Microstructure TechnologyHermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany

Single-shot X-ray phase-contrast imaging is used to take high-resolution images of laser-driven strong shock *** a two-grating Talbot interferometer,we successfully acquire standard absorption,differential phase-contrast,and dark-field images of the shocked *** agreement is demonstrated between experimental data and the results of two-dimensional radiation hydrodynamics simulations of the laser-plasma *** main sources of image noise are identified through a thorough assessment of the interferometer’s *** acquired images demonstrate that grating-based phase-contrast imaging is a powerful diagnostic tool for high-energy-density *** addition,we make a novel attempt at using the dark-field image as a signal modality of Talbot interferometry to identify the microstructure of a foam target.

关键词： interaction shock phase

住院患者认知障碍识别和信息管理的整合性综述

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International Journal of Nursing Sciences 2024年第1期11卷 120-132页

作者：熊蓓蓓 Daniel X.Bailey Paul Prudon Elaine m.Pascoe leonard C.Gray Frederick Graham Amanda Henderson melinda martin-Khan Centre for Health Services Research Faculty of MedicineThe University of QueenslandBrisbaneAustralia Centre for Clinical Research Faculty of MedicineThe University of QueenslandRoyal Brisbane&Women’s HospitalBrisbaneAustralia Dementia and Delirium Division of MedicinePrincess Alexandra HospitalBrisbaneAustralia School of Nursing Faculty of HealthQueensland University of TechnologyBrisbaneAustralia Nursing Practice Development Unit Princess Alexandra HospitalBrisbaneAustralia School of Nursing Midwifery and Social SciencesCentral Queensland UniversityBrisbaneAustralia Griffith Health Griffith UniversityBrisbaneAustralia School of Nursing Midwifery and ParamedicineThe University of the Sunshine CoastBrisbaneAustralia Department of Health and Life Sciences University of ExeterExeterUnited Kingdom School of Nursing University of Northern British ColumbiaPrince GeorgeCanada

目的旨在对目前提供急性照护的医院识别认知障碍患者以及在病历中记录和管理认知相关信息的实际情况及政策要求和推荐方法进行综述。方法采用Whittemore和Knaf1的五步法,系统检索medline,CINAHL和Scopus数据库,并检索了灰色文献来源。... 详细信息

目的旨在对目前提供急性照护的医院识别认知障碍患者以及在病历中记录和管理认知相关信息的实际情况及政策要求和推荐方法进行综述。方法采用Whittemore和Knaf1的五步法,系统检索medline,CINAHL和Scopus数据库,并检索了灰色文献来源。纳人了提供急性照护的医院已实施的患者认知障碍识别和认知信息管理相关的文献。采用混合方法评价工具和灰色文献质量评估清单对文章质量进行评价。采用主题分析法呈现和整合结果。该综述已在PROSPERO预注册(CRD42022343577)。结果共22篇原始研究文献和10篇政府/行业文件被纳人分析。结果显示,实践和政策之间存在差距。尽管在政策层面上高度重视认知障碍的识别、认知相关信息的透明度,以及与患者、家属和照顾者(如适用)之间的互动,但有时在临床实践中,认知评估是非正式的,患者的认知相关信息未作记录,与患者、家属和照顾者的互动也存在不足。结论.通过整合认知评估,利用信息技术开发信息管理综合系统,建立相关法律法规,提供教育与和培训,并采用国家层面的策略,有可能显著改善对认知障碍患者的识别和护理。

关键词：急性照护认知功能障碍数据透明度谵妄痴呆健康信息管理与患者互动.

Estimation of Equivalent model of photovoltaic Array Using Unscented Kalman Filters

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Journal of modern Power Systems and Clean Energy 2024年第3期12卷 819-827页

作者： m.A.González-Cagigal JoséA.Rosendo-macías A.Gómez-Expósito the Department of Electrical Engineering University of SevilleSpainand A.Gómez-Expósito is also with ENGREEN Laboratory of Engineering for Energy and Environmental SustainabilitySevilleSpain

This paper proposes the use of the unscented Kalman filter to estimate the equivalent model of a photovoltaic(PV)array,using external measurements of current and voltage at the inverter *** estimated model is of interest to predict the power output of PV plants,in both planning and operation scenarios,and thus improves the efficient operation of power systems with high penetration of renewable *** proposed technique has been assessed in several simulated scenarios under different operating *** results show that accurate estimates are provided for the model parameters,even in the presence of measurement noise and abrupt variations under the external conditions.

关键词： Equivalent model parameter estimation photovoltaic energy unscented Kalman filter

Sexual selection and hermaphroditic organisms： Testing theory

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Current Zoology 2013年第4期59卷 579-588页

作者： Janet L. leonard Joseph m. Long marine Laboratory University of California-Santa Cruz Santa Cruz CA 94019 USA

Sexual selection is widespread if not ubiquitous in hermaphroditic organisms. Although many phenomena that have been described as sexual selection in gonochores, （e.g. harem polygamy, multiple mating, elaborate courtship, even secondary sexual characters） can be found in some hermaphrodites, what is more interesting is the ways in which sexual selection in her- maphrodites may differ from dioecious taxa. In hermaphrodites, an individual＇s mating success includes its success from both sexual roles. Secondly, in many simultaneously hermaphroditic taxa there is strong evidence of sexual selection and yet the ope- rational sex ratio is 1：1, by definition. many simultaneous hermaphrodites have elaborate courtship and genital anatomy, suggest- ing sexual selection plays an important role in reproductive success. Sperm competition and cryptic female choice mean that the number of mates acquired is not necessarily a predictor of reproductive success. Even in simultaneous hermaphrodites with re- ciprocal mating, variance in reproductive success through the male role and through the female role may differ in a population. moreover hermaphrodites may choose to emphasize one sexual role over the other. Data suggest that the preferred role varies in hermaphrodites, which creates an opportunity to test fundamental predictions and assumptions of sexual selection theory. Hermaphrodites may vary their emphasis on one sexual role over the other either developmentally or behaviorally in response to environmental or social parameters. How they use this capability in acquiring more or higher quality mates still requires study

关键词： Sexual selection Hermaphrodites mate choice Reproductive success

User-centered development and performance assessment of a modular full-body exoskeleton (AXO-SUIT)

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Biomimetic Intelligence & Robotics 2022年第2期2卷 9-16页

作者： Shaoping Bai m.R.Islam Valerie Power leonard OŚullivan Department of materials and Production Aalborg UniversityAalborg 9220Denmark School of Design Health Research Institute and CONFIRM Smart Manufacturing CentreUniversity of LimerickIreland

This paper presents the design and preliminary performance assessment of a full-body assistive exoskeleton(AXO-SUIT)for older ***-SUIT is a system that consists of separate lower-body and upper-body modular exoskeletons,which can be combined to form a full-body system to provide flexible physical assistance as *** full-body exoskeleton comprises 27 degrees of freedom(dof),of which 17 are passive and 10 *** can assist people in walking,standing,carrying and handling tasks.A user-centered design approach was adopted throughout the development of the *** paper describes the design process of AXOSUIT,involving a review of user needs,a kinematic and kinetic motion study,and innovative system *** with the developed systems were conducted on selected end-user subjects,covering both performance evaluations at different levels and useability ***-user testing results show the effectiveness of the exoskeleton in providing flexible physical assistance.

关键词： Exoskeletons Physical assistance for the elderly User-centered design Performance assessment

Partial Protection by Lipoic Acid Against Carboplantin-induced Ototoxicity in Rats

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Biomedical and Environmental Sciences 2005年第3期18卷 198-206页

作者： KAZIm HUSAIN CRAIG WHITWORTH SATU m. SOmANI leonard P. RYBAK Departments of Surgery Southern Illinois University School of Medicine Springfield IL 62794 USADepartments of Surgery Southern Illinois University School of Medicine Springfield IL 62794 USADepartments of Pharmacology Southern Illinois University School of Medicine Springfield IL 62794 USADepartments of Surgery Southern Illinois University School of Medicine Springfield IL 62794 USA

Objective To investigate the alterations in auditory brainstem evoked responses (ABRs) and the changes of carboplatin-induced ototoxicity in the cochlear oxidant/antioxidant systems and otoprotection by an antioxidant lipoate. methods male wistar rats were divided into four groups and treated as follows: 1) vehicle (saline) control, 2) carboplatin (256 mg/kg, i.p.), 3) lipoate (100 mg/kg, i.p.), 4) lipoate + carboplatin. Post-treatment ABRs were performed after four days and rats were sacrificed with their cochleae harvested and analyzed. Results Carboplatin significantly elevated ABR threshold above the pretreatment thresholds. Lipoate+carboplatin treated rats showed decreased elevation of hearing threshold. Carboplatin significantly depleted cochlear reduced to oxizized glutathione (GSH/GSSG) ratio, whereas lipoate+carboplatin treatment increased GSH/GSSG ratio. Carboplatin significantly decreased cochlear copper zinc-superoxide dismutase (CuZn-SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and glutathione-S-transferase (GST) activities and enzyme protein expressions and a significant increase in mn-SOD activity, protein expression and malondialdehyde (mDA) level. Cochlear antioxidant enzyme activities, enzyme protein expressions and mDA level were partially restored in lipoate+carboplatin treated rats, compared to carboplatin alone. Conclusion Carboplatin-induced ototoxicity is related to impairment of cochlear antioxidant system and otoprotection conferred by lipoate is associated with partial sparing of the cochlear antioxidant defense system.

关键词： Carboplatin Alpha-lipoic acid Ototoxicity Antioxidants Rats

Heritage trees and landscape design in urban areas of Rwanda

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Journal of Forestry Research 2013年第3期24卷 561-570页

作者： Jean leonard Seburanga Qixiang Zhang Faculty of Science National University of RwandaHuye Box 117Rwanda School of Landscape Architecture Beijing Forestry University

Trees play a key role in neighborhood landscapes, a belief that has been widely held for millennia in areas beyond Sub-Saharan Africa. Unfortunately, awareness of modern landscape architecture was almost absent in Rwanda until the late 20th century. Today, houses with sur- rounding decorative and amenity plants ate a common feature in Rwanda＇s neighborhood landscapes and, as the villagization of settle- ments progresses, new kinds of landscapes are emerging. This paper explores neighborhood tree planting around human settlements in the country. Remote sensing, photogrammetry, photo interpretation, and plant surveys were the core methods used. The average tree cover frac- tion ranged between 10%-35%. As the result of what is hereafter referred to as the ＂luxury effect,＂ a discrete gradient was detected along which the diversity of ornamental and amenity trees increases with the socio-economic status of neighborhoods： from rural settlements to urban residences via a series of intermediate designs, in which different levels of human-built vegetated areas alternate with non-landscaped spaces. Showy, non-productive amenity trees tend to occur more in wealthy quarters of the inner core of cities while edible ornamentals and other productive neighborhood trees prevail in rural and spontaneous settle- ments. In general, the practice of landscape plant design, in spite of its constant improvement, is still striving to get established as a profession in the country.

关键词： heritage trees patterns settlement neighborhoods, Rwanda