检索结果-南通市图书馆

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

金粉之迷

金粉之迷

丛书名：亚森·罗平探案集

1981年

作者：（法）勒布朗（m.leblanc）李波汶译

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

水晶瓶塞 1

水晶瓶塞

1981年

作者：（法）勒勃朗（m.leblanc）周厚今译

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

蛇绿岩杂岩体中碳酸盐化超镁铁岩中的金

地球与环境 1987年第12期 92-93页

作者： G.Buisson m.leblanc 杨秋剑

在沿着阿尔卑斯型超镁铁岩体边缘产出的含碳酸盐的超镁铁岩(***等称之为滑石菱镁片岩)中,有可能找到汞、砷和钴-镍砷化物等各种矿化。金的几种产状也已查明,但是,金与滑石菱镁片岩及超镁铁质围岩的成因关系问题仍有争论。为了找到答案,... 详细信息

在沿着阿尔卑斯型超镁铁岩体边缘产出的含碳酸盐的超镁铁岩(***等称之为滑石菱镁片岩)中,有可能找到汞、砷和钴-镍砷化物等各种矿化。金的几种产状也已查明,但是,金与滑石菱镁片岩及超镁铁质围岩的成因关系问题仍有争论。为了找到答案,我们调查了上元古界(摩洛哥、沙特阿拉伯)和阿尔卑斯(利古里亚区)蛇绿岩杂岩体中含金滑石菱镁片岩。

关键词：滑石菱镁片岩碳酸盐化透镜体滑石菱镁岩超镁铁岩超镁铁质岩超基性岩蛇绿岩杂岩体杂岩

全髋关节置换病人的CT金属伪影:单能量重建和后处理算法对减少伪影效果不同但均有效

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2019年第1期 117-118页

作者： K.R.Laukamp S.Lennartz V.F.Neuhaus N.G.Hokamp R.Rau m.leblanc 许丽雪 Department of Radiology University of Cologne

摘要目的比较虚拟单能影像(VmI)、金属伪影(mA)衰减专用重建(mAR)处理后的双能CT(SDCT)和常规CT(CI)扫描减少全髋关节置换(THR)mA的效果。方法纳入27例

关键词： mA 全髋关节置换 VmI CT

应用LI-RADS v2018评估除肝细胞癌（HCC）以外的原发性肝癌：LI-RADS目标人群与无LI-RADS定义HCC危险因素病人的比较研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2020年第2期 250-250页

作者： T.J.Fraum R.Cannella D.R.Ludwig R.Tsai m.Naeem m.leblanc 胡现宁 mallinckrodt Institute of Radiology Washington University Schoolof Medicine

目的确定高风险(RF+)与非高风险(RF-)病人之间肝细胞癌(PLC)之外的非肝细胞肝癌(non-HCCPLC)LI-RADS影像征象是否存在差异,并比较RF+和RF-人群被误

关键词： HCC 肝细胞癌 LI-RADS LI-RADS v2018 原发性肝癌目标人群比较研究

Physicochemical and mechanical Performances of Technical Flax Fibers and Biobased Composite material: Effects of Flax Transformation Process

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Renewable materials 2019年第9期7卷 821-838页

作者： m.Khennache A.mahieu m.Ragoubi S.Taibi C.Poilâne N.leblanc UniLaSalle Unitéde recherche Transformations&Agro-RessourcesVAM^(2)IN(EA 7519 UniLaSalle-Universitéd’Artois)Mont Saint AignanFrance Normandie University 14032 CaenFrance UNICAEN CIMAP14032 CaenFrance ENSICAEN 14050 CaenFrance CEA UMR625214070 CaenFrance and CNRS UmR6252 14050 CaenFrance

In France,the use of flax fibers as reinforcement in composite materials is growing exponentially in the automotive sector,thanks to their good physicochemical properties,environmental reasons,health neutrality and due to the European Council Directives on the reuse,recycling and valorization of car components and *** aim of our study is to investigate biochemical,physicochemical,and mechanical properties of technical flax fibers to evaluate the impact of transformation processes(scutching,hackling,and homogenization)on final properties of associated composite *** chemical analysis such as Van Soest(biochemical fraction measurement),FTIR(Fourier Transform InfraRed spectroscopy),and XRD(X-ray diffraction)were carried out on different process modalities and show that there is no significant difference in terms of biochemical fraction and crystallinity *** the same token,mechanical behavior shows that Young’s modulus is not affected by the transformation *** result is also observed for thermal *** results highlight the fact that the transformation processes of technical fibers do not really affect their physicochemical and mechanical performances.

关键词： Technical flax physicochemical properties processes composite

Transdermal Formulation Development and Topical Administration of Atenolol to Cats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2020年第3期11卷 39-53页

作者： Sumeia m. mohamed John mark Christensen Nicole leblanc Department of Pharmaceutical Science College of Pharmacy Oregon State University Corvallis OR USA Department of Cardiology College of Veterinary Medicine Oregon State University Corvallis OR USA

Atenolol diffusion through synthetic membrane, cloned human epidermis, and cat ear skin was performed utilizing a Franz diffusion cell. Transdermal drug diffusion enhancers’ ethanol, glycerol, propylene glycol, polysorbate 80 and Dimethyl isosorbide (DmI) were added to the topical formulations and tested for their ability to enhance drug permeation through the test membranes. Topical formulation with penetration enhancers showed a rapid burst of atenolol diffusion for the first two hours (35.5 to 40 μg/ml) followed by a zero-order sustained diffusion of 2.7 μg/cm2/h of atenolol for up to twenty-four hours after application to test membranes. Increased atenolol flux through different test membranes was greatest for synthetic membrane. The topical application of the optimized atenolol formulation to cat skin containing permeation enhancers aided transdermal atenolol drug delivery to treat cats with hypertrophic obstructive cardiomyopathy. The optimum topical formulation demonstrated two fluxes through cat skin, the burst flux (15.7 μg/cm2/h) and a sustained flux (2.7 μg/cm2/h). measured atenolol concentrations in cats at 3, 6 and 12 hours after transdermal atenolol application were 432.7 ng/ml ± 323.3, 262.4 ng/ml ± 150.1, and 253.3 ng/ml ± 133.6 respectively. Six of 7 cats achieved therapeutic serum atenolol levels (260 ng/ml) for at least one time point. Five of 7 cats had therapeutic serum atenolol concentrations 3 hours post-atenolol. At the 6 hours post-atenolol time point, only 2 had a therapeutic serum atenolol concentration while at 12 hours post-atenolol dosing, 4 of 7 cats had therapeutic serum atenolol concentrations. Transdermal atenolol administered at 25 mg q12h resulted in clinically therapeutic serum atenolol concentrations in the majority of healthy cats. The optimum transdermal formulation enabled good drug delivery feasible for transdermal application in a clinical trial in cats.

关键词： Atenolol Transdermal Delivery Formulation Cats

Newfound Coding Potential of Transcripts Unveils missing members of Human Protein Communities

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2023年第3期21卷 515-534页

作者： Se´bastien leblanc marie *** Jean-Franc¸ois Jacques Amina m.Lekehal Andre´a Duclos Alexia Tremblay Alexis Bruggeman-Gascon Sondos Samandi myle`ne Brunelle Alan A.Cohen michelle S.Scott Xavier Roucou Department of Biochemistry and Functional Genomics Universite´de SherbrookeSherbrookeQC J1E 4K8Canada PROTEO Quebec Network for Research on Protein FunctionStructureand EngineeringQuebec CityQC G1V 0A6Canada Department of Family medicine Universite´de SherbrookeSherbrookeQC J1H 5N4Canada

Recent proteogenomic approaches have led to the discovery that regions of the transcriptome previously annotated as non-coding regions[i.e.,untranslated regions(UTRs),open reading frames overlapping annotated coding sequences in a different reading frame,and non-coding RNAs]frequently encode proteins,termed alternative proteins(altProts).This suggests that previously identified protein–protein interaction(PPI)networks are partially incomplete because altProts are not present in conventional protein ***,we used the proteogenomic resource OpenProt and a combined spectrum-and peptide-centric analysis for the re-analysis of a highthroughput human network proteomics dataset,thereby revealing the presence of 261 altProts in the *** found 19 genes encoding both an annotated(reference)and an alternative protein interacting with each *** the 117 altProts encoded by pseudogenes,38 are direct interactors of reference proteins encoded by their respective parental ***,we experimentally validate several interactions involving *** data improve the blueprints of the human PPI network and suggest functional roles for hundreds of altProts.

关键词： Alternative protein Protein network Protein–protein interaction Pseudogene Affinity purification mass spectrometry

Levetiracetam-Associated Acute Kidney Injury and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Nephrology 2014年第4期4卷 152-155页

作者： mathieu leblanc martin Plaisance Internal medecine Residency Program Faculté de Médecine et des Sciences de la santé Université de Sherbrooke Sherbrooke Canada Nephrology Division Department of Medicine Centre Hospitalier Universitaire de Sherbrooke Sherbrooke Canada

DRESS syndrome is a severe drug induced reaction. Acute kidney injury (AKI) is sometimes present in the form of an acute interstitial nephritis. We present the case of a 75-year-old man with glioblastoma who developed a DRESS two months after starting levetiracetam and a few days after stopping dexamethasone. His skin and kidneys improved after removing levetiracetam and introducing again corticosteroids. DRESS has been reported more frequently with other antiepileptics, rarely with levetiracetam. Clinicians should add this drug to the list of potential causes of AKI.

关键词： Acute Kidney Injury DRESS Syndrome HSV-1 Levetiracetam