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国际医学放射学杂志 2024年第2期 248-248页

作者： Y.Du m.j.cai H.L.Zha B.D.Chen j.Gu m.Q.Zhang 李晓舒

摘要目的开发并验证一种基于超声（US）影像组学的列线图，用于术前预测浸润性乳腺癌（IBC）病人淋巴血管侵袭（LVI）状态。方法回顾性连续纳入来自3个机构的456名

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An ultra-porous g-C_(3)N_(4) micro-tube coupled with mXene(Ti_(3)C_(2)TX)nanosheets for efficient degradation of organics under natural sunlight

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journal of Environmental Sciences 2024年第3期137卷 258-270页

作者： Zongyang Ya Qiyou Wang jingjin cai Peng Wang Xinyu jiang Zhiyin cai Shanglin Xiang Tingwei Wang Dongyu cai College of materials Science&Engineering Nanjing Tech University30 South PuZhu RoadNanjing 211816China Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced materials(IAm) Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)Nanjing Tech University30 South PuZhu RoadNanjing 211816China

It remains as a challenge for realizing efficient photo-responsive catalysts towards largescale degradation of organic pollutants under natural *** work reports a new pore engineering strategy for creating ultra-porous g-C_(3)N_(4) micro-tubes with an unprecedentedly high specific surface area of 152.96 m^(2)/*** is mainly associated with releasing internal vapor pressure in the autoclave where the hydrothermal treatment of the urea/melamine mixture is *** by microscopic observation,porosity measurement and spectroscopic characterization,it is found that releasing the pressure at halfway of hydrothermal process is vital for forming exfoliated rod-like precursors and the de-aggregation of these rods presents substantial benefits on the production of mesopores on g-C_(3)N_(4) microtubes during the calcination of *** offers a large number of reactive sites required by photocatalytic *** these micro-tubes with Ti_(3)C_(2)T_(X) nanosheets via electrostatic interaction yields a 1D/2D heterojunction with a close interfacial *** addition of metallically conductive Ti_(3)C_(2)T_(X) nanosheets accelerates the separation between electrons and holes,and also enhances the light *** these merits of structural design lead to forming a group of highly efficient catalysts demonstrating an excellent photocatalytic degradation rate of k=0.0560 min^(-1)for RhB dyes under 100 mW/cm~2 visible light radiation that micks sunlight *** laboratory valuation is further supported by an outdoor test that shows a fast degradation rate of 0.0744 min^(-1)under natural sunlight.

关键词： Carbon nitride mXene Heterojunction Photocatalysis

Granger causal representation learning for groups of time series

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Science China(Information Sciences) 2024年第5期67卷 56-68页

作者： Ruichu cai Yunjin WU Xiaokai HUANG Wei CHEN Tom Z.j.FU Zhifeng HAO School of Computer Science Guangdong University of Technology Peng Cheng Laboratory College of Science Shantou University

Discovering causality from multivariate time series is an important but challenging *** existing methods focus on estimating the Granger causal structures among multivariate time series,while ignoring the prior knowledge of these time series, e.g., the group of the time series. Focusing on discovering the Granger causal structures among groups of time series, we propose a Granger causal representation learning method to solve this problem. First, we use the multiset canonical correlation analysis method to learn the Granger causal representation of each group of time series. Then, we model the Granger causal relationships among the learned Granger causal representations using a recurrent neural network with temporal information. Finally, we formulate the above two stages into one unified optimization problem, which is efficiently solved using the augmented Lagrangian method. We conduct extensive experiments on synthetic and real-world datasets to validate the correctness and effectiveness of the proposed method.

关键词： Granger causal discovery Granger causal representation learning time series data recurrent neural network multiset canonical correlation analysis

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A COUPLED mETHOD COmBINING CROUZEIX-RAVIART NONCONFORmING AND NODE CONFORmING FINITE ELEmENT SPACES FOR BOIT CONSOLIDATION mODEL

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journal of Computational mathematics 2024年第4期42卷 911-931页

作者： Yuping Zeng mingchao cai Liuqiang Zhong School of mathematics Jiaying UniversityMeizhou 514015China Department of mathematics Morgan State University1700 E Cold Spring LnBaltimoreMD 21251USA School of mathematical Science South China Normal UniversityGuangzhou 520631China

A mixed finite element method is presented for the Biot consolidation problem in *** precisely,the displacement is approximated by using the Crouzeix-Raviart nonconforming finite elements,while the fuid pressure is approximated by using the node conforming finite *** well-posedness of the fully discrete scheme is established,and a corresponding priori error estimate with optimal order in the energy norm is also *** experiments are provided to validate the theoretical results.

关键词： Poroelasticity Nonconforming finite element Inf-sup condition A priori error estimate

Impact of COVID-19 on the energy consumption of commercial buildings:A case study in Singapore

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Energy and Built Environment 2024年第3期5卷 364-373页

作者： Senhong cai Zhonghua Gou School of Urban Design Wuhan UniversityWuhanChina

Numerous studies have demonstrated that commercial activities have significantly reduced during COVID-19,while there are few studies disclosing the consequent impacts on the energy consumption of commercial *** study explores the changes in energy consumption of different types of commercial buildings in Sin-gapore under the impact of the pandemic,using commercial building energy performance data from 2017 to 2020(n=540).The sampled buildings include 93 hotel buildings,303 office buildings,106 retail buildings,and 38 mixed *** analysis mainly used linear regression and paired sample *** results showed that relative to 2019,the mean energy use intensity(EUI)of sampled commercial buildings decreased by 56.77 kWh/m^(2)in the pandemic year(2020),a plunge of 19.9%.The extent to which the EUI of each type of commercial building is affected by the pandemic is found as:mixed development>retail>office>*** study also identi-fied the factors that significantly influenced the EUI of commercial buildings before and during the *** results of the study complement existing knowledge about the factors influencing energy consumption in com-mercial buildings by considering the impact of the pandemic and furthermore contribute to the improvement of energy management in commercial buildings by providing directions for building energy efficiency approaches.

关键词： Commercial buildings Energy consumption Energy use intensity Impact of COVID-19 Influential factors

Luminescence regulation of Sb^(3+)in 0D hybrid metal halides by hydrogen bond network for optical anti-counterfeiting

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Opto-Electronic Advances 2024年第3期7卷 15-25页

作者： Dehai Liang Saif m.H.Qaid Xin Yang Shuangyi Zhao Binbin Luo Wensi cai Qingkai Qian Zhigang Zang Key Laboratory of Optoelectronic Technology&Systems(ministry of Education) Chongqing UniversityChongqing 400044China Department of Physics&Astronomy College of SciencesKing Saud UniversityP.O.Box 2455Riyadh 11451Saudi Arabia Department of Chemistry and Chemical Engineering Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong ProvinceShantou UniversityShantou 515063China Department of Oil Army Logistics Academy of PLAChongqing 401311China

The Sb^(3+) doping strategy has been proven to be an effective way to regulate the band gap and improve the photophysical properties of organic-inorganic hybrid metal halides(OIHmHs).However,the emission of Sb^(3+) ions in OIHmHs is primarily confined to the low energy region,resulting in yellow or red *** date,there are few reports about green emission of Sb^(3+)-doped ***,we present a novel approach for regulating the luminescence of Sb^(3+) ions in 0D C_(10)H_(2)_(2)N_(6)InCl_(7)·H_(2)O via hydrogen bond network,in which water molecules act as agents for hydrogen ***^(3+)-doped C_(10)H_(2)2N_(6)InCl_(7)·H_(2)O shows a broadband green emission peaking at 540 nm and a high photoluminescence quantum yield(PLQY)of 80%.It is found that the intense green emission stems from the radiative recombination of the self-trapped excitons(STEs).Upon removal of water molecules with heat,C_(10)H_(2)_(2)N_(6)In_(1-x)Sb_(x)Cl_(7) generates yellow emis-sion,attributed to the breaking of the hydrogen bond network and large structural distortions of excited *** water molecules are adsorbed by C_(10)H_(2)_(2)N_(6)In_(1-x)Sb_(x)Cl_(7),it can subsequently emit green *** water-induced reversible emission switching is successfully used for optical security and information *** findings expand the under-standing of how the local coordination structure influences the photophysical mechanism in Sb^(3+)-doped metal halides and provide a novel method to control the STEs emission.

关键词： indium-based halides Sb^(3+)doping hydrogen bonding network optical anti-counterfeiting

Induced pluripotent stem cells(iPSCs):molecular mechanisms of induction and applications

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2065-2090页

作者： jonas Cerneckis Hongxia cai Yanhong Shi Department of Neurodegenerative Diseases Beckman Research Institute of City of HopeDuarteCA 91010USA Irell&manella Graduate School of Biological Sciences Beckman Research Institute of City of HopeDuarteCA 91010USA

The induced pluripotent stem cell(iPSC)technology has transformed in vitro research and holds great promise to advance regenerative *** have the capacity for an almost unlimited expansion,are amenable to genetic engineering,and can be differentiated into most somatic cell *** have been widely applied to model human development and diseases,perform drug screening,and develop cell *** this review,we outline key developments in the iPSC field and highlight the immense versatility of the iPSC technology for in vitro modeling and therapeutic *** begin by discussing the pivotal discoveries that revealed the potential of a somatic cell nucleus for reprogramming and led to successful generation of *** consider the molecular mechanisms and dynamics of somatic cell reprogramming as well as the numerous methods available to induce ***,we discuss various iPSC-based cellular models,from mono-cultures of a single cell type to complex three-dimensional organoids,and how these models can be applied to elucidate the mechanisms of human development and *** use examples of neurological disorders,coronavirus disease 2019(COVID-19),and cancer to highlight the diversity of disease-specific phenotypes that can be modeled using iPSC-derived *** also consider how iPSC-derived cellular models can be used in high-throughput drug screening and drug toxicity ***,we discuss the process of developing autologous and allogeneic iPSC-based cell therapies and their potential to alleviate human diseases.

关键词： mechanisms programming holds

Nanomedicine targeting ferroptosis to overcome anticancer therapeutic resistance

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Science China(Life Sciences) 2024年第1期67卷 19-40页

作者： jing cai Xiaoding Xu Phei Er Saw Guangdong Provincial Key Laboratory of malignant Tumor Epigenetics and Gene Regulation Guangdong-Hong Kong Joint Laboratory for RNA MedicineMedical Research CenterSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Nanhai Translational Innovation Center of Precision Immunology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityFoshan 528200China

A potential reason for the failure of tumor therapies is treatment *** to chemotherapy,radiotherapy,and immunotherapy continues to be a major obstacle in clinic,resulting in tumor recurrence and *** major mechanisms of therapy resistance are inhibitions of cell deaths,like apoptosis and necrosis,through drug inactivation and excretion,repair of DNA damage,tumor heterogeneity,or changes in tumor microenvironment,*** studies have shown that ferroptosis play a major role in therapies resistance by inducing phospholipid peroxidation and iron-dependent cell *** ferroptosis inducers in combination with clinical treatment techniques have been used to enhance the effect in tumor ***,versatile ferroptosis nanoinducers exhibit an extensive range of functions in reversing therapy resistance,including directly triggering ferroptosis and feedback ***,we provide a detailed description of the design,mechanism,and therapeutic application of ferroptosis-mediated synergistic tumor *** also discuss the prospect and challenge of nanomedicine in tumor therapy resistance by regulating ferroptosis and combination therapy.

关键词： ferroptosis cancer therapy therapy resistance nanoinducers

Optimized silicon fertilization regime weakens cadmium translocation and increases its biotransformation in rice tissues

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The Crop journal 2024年第4期12卷 1041-1053页

作者： Bogui Pan Yixia cai Kunzheng cai jihui Tian Wei Wang College of Natural Resources and Environment South China Agricultural UniversityGuangzhou 510642GuangdongChina Guangdong Provincial Key Laboratory of Eco-Circular Agriculture Guangzhou 510642GuangdongChina Key Laboratory of Tropical Agricultural Environment in South China Ministry of Agriculture and Rural AffairsGuangzhou 510642GuangdongChina College of Agriculture South China Agricultural UniversityGuangzhou 510642GuangdongChina

In acidic paddy fields of South China,rice(Oryza sativa L.)faces the dual challenges of cadmium(Cd)toxicity and silicon(Si)*** previous studies have highlighted the functions of Si application timing and strategies in mitigating Cd-stressed rice,the precise mechanisms underlying the health restoration of Cd-toxic rice and the assurance of grain safety remain *** study explored Cd translocation and detoxification in the shoots of rice regulated by various Si fertilization regimes:Si(T)(all Si added before transplanting),Si(j)(all Si added at jointing),and Si(Tj)(half Si added both before transplanting and at jointing).The findings revealed that the regime of Si(Tj)was more beneficial to rice health and grain safety than Si(T)and Si(j).The osmotic regulators such as proline,soluble sugars,and soluble proteins were significantly boosted by Si(Tj)compared to other Si treatments,and which enhanced membrane integrity,balanced intracellular pH,and increased Cd tolerance of ***,Si(Tj)was more effective than Si(T)and Si(j)on the Cd sequestration in the cell wall,Cd bio-passivation,and the down-regulated expression of the Cd transport *** concentrations of Cd in the xylem and phloem treated with Si(Tj)were reduced ***,Si(Tj)facilitated much more Cd bound with the outer layer proteins of grains,and promoted Cd chelation and complexation by phytic acid,phenolics,and ***,Si(Tj)outperformed Si(T)and Si(j)in harmonizing the phycological processes,inhibiting Cd translocation,and enhancing Cd detoxification in rice *** the split Si application strategy offers potential for reducing Cd toxicity in rice grain.

关键词： Cadmium Silicon Growth stages Translocation and accumulation Rice Safe production

Particle residence time distribution and axial dispersion coefficient in a pressurized circulating fluidized bed by using multiphase particle-in-cell simulation

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Chinese journal of Chemical Engineering 2024年第5期69卷 167-176页

作者： jinnan Guo Daoyin Liu jiliang ma cai Liang Xiaoping Chen Key Laboratory of Energy Thermal Conversion and Control of ministry of Education Southeast UniversityNanjing 210096China

The particle residence time distribution(RTD)and axial dispersion coefficient are key parameters for the design and operation of a pressurized circulating fluidized bed(PCFB).In this study,the effects of pressure(0.1-0.6 mPa),fluidizing gas velocity(2-7 m·s^(-1)),and solid circulation rate(10-90 kg·m^(-2)·s^(-1))on particle RTD and axial dispersion coefficient in a PCFB are numerically investigated based on the multiphase particle-in-cell(mP-PIC)*** details of the gas-solid flow behaviors of PCFB are *** on the gas-solid flow pattern,the particles tend to move more orderly under elevated *** an increase in either fluidizing gas velocity or solid circulation rate,the mean residence time of particles decreases while the axial dispersion coefficient *** an increase in pressure,the core-annulus flow is strengthened,which leads to a wider shape of the particle RTD curve and a larger mean particle residence *** back-mixing of particles increases with increasing pressure,resulting in an increase in the axial dispersion coefficient.

关键词： Pressurized circulating fluidized bed mP-PIC method Residence time distribution Axial dispersion coefficient