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Thermal decomposition of ammonium perchlorate catalyzed with CuO nanoparticles

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Defence Technology（防务技术） 2019年第6期15卷 868-874页

作者： Sherif Elbasuney m.yehia head of Nanotechnology Research Center School of Chemical EngineeringMilitary Technical College

Ammonium perchlorate(APC)is the most common oxidizer in use for solid rocket propulsion *** its initial thermal decomposition is an endothermic process that requires 102.5 J·g^-*** manner involves high activation energy and could render high burning rate *** study reports on the sustainable fabrication of CuO nanoparticles as a novel catalyzing agent for APC *** CuO nanoparticles with consistent product quality were fabricated by using hydrothermal *** micrographs demonstrated mono-dispersed particles of 15 nm particle *** diffractogram demonstrated highly crystalline *** synthesized colloidal CuO particles were effectively coated with APC particles via co-precipitation by using fast-crash solvent-antisolvent *** impact of copper oxide particles on APC thermal behavior has been investigated using DSC and TGA *** demonstrated an initial endothermic decomposition stage at 242℃ with subsequent two exothermic decomposition stages at 297,8℃ and 452.8℃ *** 1 wt%,copper oxide offered decrease in initial endothermic decomposition stage by 30%.The main outcome of this study is that the two main exothermic decomposition peaks were merged into one single peak with an increase in total heat release by 53%.These novel features can inherit copper oxide particles unique catalyzing ability for advanced highly energetic systems.

关键词： Ammonium perchlorate Catalyst Thermal behavior Energetic systems Catalyzed propellants

Novel synthesis of stabilized Bi_(1-x-y)Gd_(x)Dy_(y)O_(1.5) solid electrolytes with enhanced conductivity for intermediate temperature solid oxide fuel cells(SOFCs)

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Journal of Rare Earths 2024年第10期42卷 1903-1911页

作者： Ahmed h.Ibrahim yehia m.Abbas h.A.Ayoub marwa h.Ali mustafa Aldoori materials Science Laboratory Physics DepartmentFaculty of ScienceSuez Canal University41522IsmailiaEgypt ministry of higher Education and Scientific Research Aliraqia University10011BaghdadIraq

herein,we report the synthesis of a Dy-Gd co-doped cubic phase-stabilized Bi_(2)O_(3) solid electrolyte system via solid-state processing under atmospheric *** with Dy^(3+) and Gd^(3+) has been observed to significantly enhance the densification process during sintering for stabilization purposes,thereby improving the electrical properties of δ-Bi_(2)O_(3)-type *** synthesized ceramics were characterized using X-ray diffraction(XRD),field emission scanning electron microscopy-energy dispersive X-ray spectroscopy(FESEm-EDX),thermal gravimetry/differential thermal analysis(TG/DTA),and the four-point probe technique(4PPT).XRD analysis reveals that the samples Bi_(1-x-y)Gd_(x)Dy_(y)O_(1.5)(y=0.05/x=0.05,0.10,0,15,and 0.20,and x=0.05/y=0.10,0.15,and 0.20) exhibit a stable face-centered cubic δ-phase and a mixed-phase crystallographic *** XRD analysis of the stabilized δ-phase suggests that the prepared oxides show a face-centered cubic(FCC) structure with a space group of *** micrographs reveal that the composition Bi_(0.90)Gd_(0.05)Dy_(0.05)O_(1.5) has no significant ***,an evident increase in the pore formation is observed as the amount of Gd_(2)O_(3) increases until it reaches 20%.This finding suggests that dense pellets are formed during the sintering process at 900-1000℃.The DTA analyses were performed to verify the phase stability,which agrees with the XRD *** electrochemical performance of the synthesized Dy-Gd co-doped Bi_(2)O_(3)solid electrolyte system was evaluated and analyzed in detail by using the electrochemical impedance spectroscopy(EIS) technique,Based on EIS and conductivity measurements,Bi_(0.75)Gd_(0.20)Dy_(0.05)O_(1.5) exhibits the lowest activation energy of 0.519 eV and the highest conductivity value of 0.398 S/cm at 627℃compared to the other samples;this composition can be used as a solid electrolyte for intermediatetemperature solid oxide fuel cells(SOFCs).

关键词： Solid oxide fuel cells(SOFCs) Rare earths Solid-state processing Rietveld Fast Fourier transform(FFT) Electrochemical impedance spectroscopy(EIS)

A combined contour lines iteration algorithm and Delaunay triangulation for terrain modeling enhancement

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Geo-Spatial Information Science 2023年第3期26卷 558-576页

作者： yehia miky Abdullah Kamel Ahmed Alshouny Department of Geomatics King Abdul aziz UniversityJeddahSaudi Arabia Faculty of Engineering Aswan UniversityAswanEgypt National Water Research Center Survey Research InstituteGizaEgypt

Digital Elevation models(DEms)play a crucial role in civil and environmental applications,such as hydrologic and geologic analyses,hazard monitoring,natural resources exploration,***,DEms can be generated from various data sources,such as ground surveys,photogrammetric stereo methods,satellite images,laser scanning,and digitized contour *** with other data sources,contour lines are still the cheapest and more common data source becausethey cover all areas,at different scales,in most *** there are different algorithms and technologies for interpolation in between contour lines,DEms extracted solely from contours still suffer from poor terrain quality representation,which in turn negatively affects the quality of analytical applications *** this paper,an approach for improving the digital terrain modeling based on contour line densification and Delaunay triangulation is presented to acquire a more suitable DEm for hydrographic modeling and its *** proposed methodology was tested using a variety of terrain patterns in terms of intensity:hilly,undulated,and plain(1:25,000 topographic map,5 m contour interval).The precision of the extracted GRID model increases as the number of added contours *** four contour lines,the Root mean Square Error(RmSE)of examining points were 0.26 m,0.29 m,and 0.05 m for hilly,undulated,and plain samples,respectively,and the mean Absolute Error(mAE)were 0.50 m,0.48 m,and 0.17 *** convergence probabilities between extracted and original flow lines for the same regions were 96.91%,94.93%,and 84.03%.Applying the methodology,experimental results indicate that the developed approach provides a significant advantage in terrain modeling enhancement,generates DEms smoothly and effectively from contours,mitigates problems and reduces uncertainties.

关键词： Contours Digital Elevation model(DEm) Triangulated Irregular Network(TIN) Delaunay triangulation

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. however, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

Brain-penetrating neurotrophic factor mimetics: hER-096 as a disease-modifying therapy for Parkinson’s disease

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Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.holmström henri J.huttunen herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying *** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatment therapeutic

Thermochemical Aspects of Activated Ammonium Perchlorates with Superior Thermal Stability,Decomposition Enthalpy,Propagation Index,and Decomposition Kinetic Parameters

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Journal of Thermal Science 2021年第6期30卷 2196-2201页

作者： ShERIF Elbasuney m.yehia ShUKRI Ismael ShERIF Farag AhmED Saleh GhARIEB S.El-Sayyad head of Nanotechnology Research Center Military Technical College(MTC)Cairo 11646Egypt School of Chemical Engineering Military Technical College(MTC)Cairo 11646Egypt Science and Technology Center of Excellence Cairo 11646Egypt Drug Radiation Research Department National Center for Radiation Research and Technology(NCRRT)Egyptian Atomic Energy Authority(EAEA)Cairo 11646Egypt

Ammonium perchlorate(AP)includes oxidizing and reducing elements on the same *** can act as an efficient oxidizer and mono-propellant as *** this study,AP experienced crystallographic phase change from orthorhombic centrosymmetric to non-centrosymmetric under controlled isothermal heat *** diffractograms confirmed this crystallographic phase *** thermal behaviour of activated AP had been investigated using *** AP demonstrated high chemical stability with an increase in endothermic phase transition enthalpy by 170%.The enthalpy of the subsequent two main exothermic decomposition reactions was increased by 250%.Whereas AP demonstrated total decomposition enthalpy of 733 J/g,activated AP showed 2614 J/*** AP can secure self-sustained response at a high *** index(combustion enthalpy/ignition temperature)was employed to assess self-sustained reaction *** AP demonstrated high propagation index of 8.7 compared with 2.5 for un-activated *** decomposition kinetic parameters had investigated using Kissinger and KAS *** AP showed an increase in activation energy by 89%using the Kissinger method;kinetic parameters using the KAS method were in good agreement with the Kissinger *** can have concluded that AP with novel kinetic decomposition parameters for enhanced safety storage and high combustion characteristics has evolved.

关键词： solid propellants oxidizers thermal behavior Kinetic parameters activation energy

Search for microglia-specific peptides:advances in the discovery toolbox

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Neural Regeneration Research 2025年第2期20卷 471-472页

作者： Ivan Sarabia Kyle m.Koss Department of Surgery University of ArizonaTucsonAZUSA

Uncontrolled and chronic inflammatory states in the central nervous system(CNS)are the hallmark of neurodegenerative pathology and every injury or stroke-related *** key mediators of these neuroinflammatory states are glial cells known as microglia,the resident immune cell at the core of the inflammatory event,and astroglia,which encapsulate inflammatory insults in proteoglycan-rich scar *** gliotic scar blocks significant portions of healthy axonal networking,preventing *** most neuroinflammation is exclusively based on the responses of said microglia,their phenotypes are suggested to follow those of macrophages;m1 and m2 are opposites of pro-and ***,microglial phenotypes have been identified to be on an inflammatory spectrum encompassing developmental,homeostatic,and reparative behaviors as opposed to their ability to affect devastating cell death cascades and scar tissue formation.

关键词： inflammation pathology death

SBL-JP-0004: A promising dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology research 2025年第1期33卷 235-243页

作者： hassan m Otifi Department of Pathology College of Medicine King Khalid University Abha 62521 Saudi Arabia.

Background:Gastric cancer (GC) remains a global health burden and is often characterized by heterogeneous molecular profiles and resistance to conventional therapies. The phosphoinositide 3-kinase and PI3K and Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathways play pivotal roles in GC progression, making them attractive targets for therapeutic interventions.methods:This study applied a computational and molecular dynamics simulation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD kinases. KATOIII and SNU-5 GC cells were used for evaluation.Results:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases, as evidenced by molecular docking scores and molecular dynamics simulations. Binding interactions and Gibbs binding free energy estimates confirmed stable and favorable interactions with target proteins. SBL-JP-0004 displayed an half-maximal inhibitory concentration (IC) value of 118.9 nm against JAK2 kinase and 200.9 nm against PI3KCD enzymes. SBL-JP-0004 exhibited potent inhibition of cell proliferation in KATOIII and SNU-5 cells, with half-maximal growth inhibitory concentration (GI) values of 250.8 and 516.3 nm, respectively. A significant elevation in the early phase apoptosis (28.53% in KATOIII cells and 26.85% in SNU-5 cells) and late phase apoptosis (17.37% in KATOIII cells and 10.05% in SNU-5 cells) were observed with SBL-JP-0004 treatment compared to 2.1% and 2.83% in their respective controls.Conclusion:The results highlight SBL-JP-0004 as a promising dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Dual inhibition Gastric cancer (GC) JAK2 molecular docking molecular dynamics simulation PI3KCD SBL-JP-0004