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Trauma to the solid abdominal organs:The missed dark box of colonoscopy

World Journal of Gastroenterology 2024年第7期30卷 624-630页

作者： mohamed h Emara Usama mazid Yasmine A Elshaer mahmoud A Elkerdawy Dilaver Farooq malik Aya m mahros Department of hepatology Gastroenterologyand Infectious DiseasesKafrelsheikh UniversityKafr-Elshikh 33516Egypt Department of medicine Alyousif HospitalAlkhobar 31952Saudi Arabia

Colonoscopy is an integral part of the lower bowel care and is generally considered a potentially safe diagnostic and therapeutic procedure performed as a daycare outpatient *** is associated with different complications that are not limited to adverse events related to the bowel preparation solutions used,the sedatives used,but to the procedure related as well including bleeding and *** to the extra-luminal abdominal organs during colonoscopy are uncommon,however,serious complications related to the procedure have been reported infrequently in the *** threatening injuries to the spleen,liver,pancreas,mesentery,and urinary bladder have been reported as early as in *** injuries should not be overlooked by clinicians and *** increasing abdominal pain,abdominal distension,and hemodynamic instability in absence of rectal bleeding should raise the possibility of severe organ *** and hepatic injury following colonoscopy are usually serious and may be life *** conservative management may help,yet they usually need interventional radiology or surgical *** pancreatitis following colonoscopy is usually mild and is mostly managed *** mechanism of abdominal organ injuries during colonoscopy is not fully understood,however many risk factors have been identified,which can be classified as-organ related,procedure related,and local abdominal *** colonoscopy and prior intra-abdominal adhesions are probably the most relevant risk factors for these *** lateral position,avoidance of looping and excessive force during the procedure would probably reduce the risk of such injuries.

关键词： Colonoscopy Pancreatitis Trauma Complications Adhesions

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Role of marine natural products in the development of antiviral agents against SARS‑CoV‑2:potential and prospects

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marine Life Science & Technology 2024年第2期6卷 280-297页

作者： D.P.Nagahawatta N.m.Liyanage Thilina U.Jayawardena h.h.A.C.K.Jayawardhana Seong‑hun Jeong hyung‑Jun Kwon You‑Jin Jeon Department of marine Life Sciences Jeju National UniversityJeju 690-756Republic of Korea Department of Chemistry Biochemistry and PhysicsUniversitédu QuébecàTrois-RivièresTrois-RivièresQC G8Z 4M3Canada marine Science Institute Jeju National UniversityJeju 63333Republic of Korea Functional Biomaterial Research Center Korea Research Institute of Bioscience and BiotechnologyJeongeup-siRepublic of Korea

A novel coronavirus,known as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has surfaced and caused global concern owing to its ***-CoV-2 is the causative agent of coronavirus disease 2019;however,it was only discovered at the end of the year and was considered a pandemic by the World health ***,the develop-ment of novel potent inhibitors against SARS-CoV-2 and future outbreaks is urgently *** naturally occurring bioactive substances have been studied in the clinical setting for diverse *** intricate infection and replication mechanism of SARS-CoV-2 offers diverse therapeutic drug targets for developing antiviral medicines by employing natural products that are safer than synthetic *** natural products(mNPs)have received increased attention in the development of novel drugs owing to their high diversity and ***,this review article investigates the infection and replication mechanisms,including the function of the SARS-CoV-2 genome and ***,we highlighted anti-SARS-CoV-2 therapeutic intervention efforts utilizing mNPs and predicted SARS-CoV-2 inhibitor design.

关键词： SARS-CoV-2 marine natural products Drug targets Inhibitors

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Swelling-induced finite bending of functionally graded ph-responsive hydrogels:a semi-analytical method

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Applied mathematics and mechanics(English Edition) 2019年第5期40卷 679-694页

作者： m.shojaeifard m.R.BAYAT m.BAGhANI School of mechanical Engineering College of Engineering University of Tehran

Recently, ph-sensitive hydrogels have been utilized in the diverse applications including sensors, switches, and actuators. In order to have continuous stress and deformation ?elds, a new semi-analytical approach is developed to predict the swelling induced?nite bending for a functionally graded(FG) layer composed of a ph-sensitive hydrogel,in which the cross-link density is continuously distributed along the thickness direction under the plane strain condition. Without considering the intermediary virtual reference,the initial state is mapped into the deformed con?guration in a circular shape by utilizing a total deformation gradient tensor stemming from the inhomogeneous swelling of an FG layer in response to the variation of the ph value of the solvent. To enlighten the capability of the presented analytical method, the ?nite element method(FEm) is used to verify the accuracy of the analytical results in some case studies. The perfect agreement con-?rms the accuracy of the presented method. Due to the applicability of FG ph-sensitive hydrogels, some design factors such as the semi-angle, the bending curvature, the aspect ratio, and the distributions of deformation and stress ?elds are studied. Furthermore, the tangential free-stress axes are illustrated in deformed con?guration.

关键词： ph-sensitive hydrogel functionally graded(FG)layer finite bending semianalytical solution finite element method(FEm)

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A hybrid machine-learning model for solar irradiance forecasting

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CLEAN ENERGY 2024年第1期8卷 100-110页

作者： Almarzooqi, Ameera m. maalouf, maher El-Fouly, Tarek h. m. Katzourakis, Vasileios E. El moursi, mohamed S. Chrysikopoulos, Constantinos, V Khalifa Univ Dept Ind & Syst Engn POB 127788 Abu Dhabi U Arab Emirates Khalifa Univ Abu Dhabi Elect Engn & Comp Sci Dept Abu Dhabi U Arab Emirates Khalifa Univ Dept Civil Infrastruct & Environm Engn POB 127788 Abu Dhabi U Arab Emirates Tech Univ Crete Sch Chem & Environm Engn Khania 73100 Greece

Nowcasting and forecasting solar irradiance are vital for the optimal prediction of grid-connected solar photovoltaic (PV) power plants. These plants face operational challenges and scheduling dispatch difficulties due to the fluctuating nature of their power output. As the generation capacity within the electric grid increases, accurately predicting this output becomes increasingly essential, especially given the random and non-linear characteristics of solar irradiance under variable weather conditions. This study presents a novel prediction method for solar irradiance, which is directly in correlation with PV power output, targeting both short-term and medium-term forecast horizons. Our proposed hybrid framework employs a fast trainable statistical learning technique based on the truncated-regularized kernel ridge regression model. The proposed method excels in forecasting solar irradiance, especially during highly intermittent weather periods. A key strength of our model is the incorporation of multiple historical weather parameters as inputs to generate accurate predictions of future solar irradiance values in its scalable framework. We evaluated the performance of our model using data sets from both cloudy and sunny days in Seattle and medford, USA and compared it against three forecasting models: persistence, modified 24-hour persistence and least squares. Based on three widely accepted statistical performance metrics (root mean squared error, mean absolute error and coefficient of determination), our hybrid model demonstrated superior predictive accuracy in varying weather conditions and forecast horizons. A novel prediction method for solar irradiance, targeting both short-term and medium-term forecast horizons, is proposed to improve PV power production. The hybrid framework employs a fast trainable statistical learning technique based on the truncated-regularized kernel ridge regression model. Graphical Abstract

关键词： solar power generation kernel ridge regression hybrid model forecasting BATTERY ENERGY-STORAGE POWER PV RADIATION PREDICTION CELLS

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Composite Fractional Trapezoidal Rule with Romberg Integration

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Computer modeling in Engineering & Sciences 2024年第9期140卷 2729-2745页

作者： Iqbal m.Batiha Rania Saadeh Iqbal h.Jebril Ahmad Qazza Abeer A.Al-Nana Shaher momani Department of mathematics Al Zaytoonah University of JordanAmman11733Jordan Nonlinear Dynamics Research Center(NDRC) Ajman UniversityAjman 346United Arab Emirates Department of mathematics Faculty of ScienceZarqa UniversityZarqa13110Jordan Department of mathematics Prince Sattam Bin Abdulaziz UniversityAlkharj11942Saudi Arabia Department of mathematics The University of JordanAmman11942Jordan

The aim of this research is to demonstrate a novel scheme for approximating the Riemann-Liouville fractional integral *** would be achieved by first establishing a fractional-order version of the 2-point Trapezoidal rule and then by proposing another fractional-order version of the(n+1)-composite Trapezoidal *** particular,the so-called divided-difference formula is typically employed to derive the 2-point Trapezoidal rule,which has accordingly been used to derive a more accurate fractional-order formula called the(n+1)-composite Trapezoidal ***,in order to increase the accuracy of the proposed approximations by reducing the true errors,we incorporate the so-called Romberg integration,which is an extrapolation formula of the Trapezoidal rule for integration,into our proposed *** numerical examples are provided and compared with a modern definition of the Riemann-Liouville fractional integral operator to illustrate the efficacy of our scheme.

关键词： Composite fractional Trapezoidal rule Romberg integration

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Trehalose:A sugar molecule involved in temperature stress management in plants

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The Crop Journal 2024年第1期12卷 1-16页

作者： Ali Raza Savita Bhardwaj md Atikur Rahman Pedro García-Caparrós madiha habib Faisal Saeed Sidra Charagh Christine h.Foyer Kadambot h.m.Siddique Rajeev K.Varshney College of Agriculture Fujian Agriculture and Forestry University(FAFU)Fuzhou 350002FujianChina Department of Botany School of Bioengineering and BiosciencesLovely Professional UniversityPhagwara 144411India Department of Botany MCM DAV CollegeKangraHimachal Pradesh 176001India Grassland and Forage Division National Institute of Animal ScienceRural Development AdministrationCheonan 31000Republic of Korea Agronomy Department of Superior School Engineering University of AlmeríaAlmeríaSpain National Institute for Genomics and Advanced Biotechnology National Agricultural Research CentrePark Rd.Islamabad 45500Pakistan Agriculture Health and Environment DepartmentNatural Resources InstituteFaculty of Engineering&ScienceUniversity of GreenwichKent ME44TBUK State Key Laboratory of Rice Biology China National Rice Research InstituteChinese Academy of Agricultural SciencesHangzhouZhejiangChina School of Biosciences College of Life and Environmental SciencesUniversity of BirminghamEdgbaston B152TTUK The UWA Institute of Agriculture The University of Western AustraliaCrawleyPerth 6009Australia WA State Agricultural Biotechnology Centre Centre for Crop and Food InnovationFood Futures InstituteMurdoch UniversityMurdochWA 6150Australia

Trehalose(Tre)is a non-reducing disaccharide found in many species,including bacteria,fungi,invertebrates,yeast,and even plants,where it acts as an osmoprotectant,energy source,or protein/membrane *** relatively small amounts in plants,Tre concentrations increase following exposure to abiotic ***-6-phosphate,a precursor of Tre,has regulatory functions in sugar metabolism,crop production,and stress *** the various abiotic stresses,temperature extremes(heat or cold stress)are anticipated to impact crop production worldwide due to ongoing climate *** small amounts of Tre can mitigate negative physiological,metabolic,and molecular responses triggered by temperature *** also interacts with other sugars,osmoprotectants,amino acids,and phytohormones to regulate metabolic reprogramming that underpins temperature stress *** plants expressing Tre-synthesis genes accumulate Tre and show improved stress ***-wide studies of Tre-encoding genes suggest roles in plant growth,development,and stress *** review discusses the functions of Tre in mitigating temperature stress—highlighting genetic engineering approaches to modify Tre metabolism,crosstalk,and interactions with other molecules—and in-silico approaches for identifying novel Tre-encoding genes in diverse plant *** consider how this knowledge can be used to develop temperature-resilient crops essential for sustainable agriculture.

关键词： Abiotic stress Gene expression Genetic engineering Osmolyte Trehalose-6-phosphate

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Kaoline-based catalyst for a high stability desulfurization of sour heavy naphtha in a three-phase oscillatory baffled reactor

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Particuology 2024年第1期84卷 249-260页

作者： hassan m.hmood Saba A.Gheni Safaa m.R.Ahmed mudheher m.Ali hamid Yonis Saleh mohammed h.mohammed Awad E.mohammed marwan A.mahomood hiba R.mohammed Ahmed A.hassan Adam harvey North Refineries Company Ministry of OilIraq Chemical Engineering Department Tikrit UniversityIraq ministry of Oil Iraq AL-hawija Technical Institute Northern Technical UniversityMoselIraq School of Engineering Newcastle UniversityUK

To meet the rapidly increasing demand for energy and the dramatic depletion of conventional crude oil,it is imperative to utilize sour *** no coke being produced,oxidative desulfurization(ODS)of naphtha lowers its sulfur content and average molecular *** this article,we outline a method for heavy naphtha non-extractive ODS using a very stable *** technique involves the use of a solid catalyst with oxygen gas as the *** necessitated relatively high mixing intensities;hence a three-phase Oscillatory Baffled Reactor(OBR)was *** catalyst was based on the zeolite ZSm-5,prepared from natural kaolin by a series of delamination and activation steps and impregnated with Fe.A TiO2 nanolayer was applied,using the sol-gel method,to prevent rapid *** reactor performance was evaluated to minimize the sulfur content in the naphtha *** to the protective coating,the sulfur conversion stabilized at 90%.The results of this work establish the use of natural clay-based catalysts in a continuous,three-phase ODS,particularly with regard to proving long-term *** also showed that modest ODS can be achieved using an environmentally friendly oxidant,at mild operating conditions,whilst maintaining stability.

关键词： Natural kaoline Desulfurization Three-phase Oscillatory baffled reactor

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BENDING BEhAVIOR OF EmPTY AND FOAm-FILLED ALUmINUm TUBES WITh DIFFERENT CROSS-SECTIONS

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Acta mechanica Solida Sinica 2012年第6期25卷 616-626页

作者： m. h. shojaeifard h. R. Zarei R. Talebitooti m. mehdikhanlo School of Automotive Engineering Iran University of Science and Technology Faculty of Aerospace Engineering Aeronautical University of Science and Technology

In this paper, the energy absorption mechanism of empty and foam-filled aluminum tubes with different cross-sections （circular, square and elliptic） under bending load is investigated numerically. The load-displacement curves of the present simulations are in very good agreement with those of published experimental data. here, the existing analytical formulations are reviewed and compared with experimental results. In addition, the effects of different cross-sections and wall thicknesses on the energy absorption capacity and specific energy absorption of these tubes are fully investigated. The results indicate that the energy absorption of an elliptic foam-filled tube with 1.5 mm and 2 mm thicknesses increases about 45% and 73% in comparison with a square one, respectively.

关键词： plastic bending foam filled energy absorption

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mgO-attached graphene nanosheet(mgO@GNS)reinforced magnesium matrix nanocomposite with superior mechanical,corrosion and biological performance

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International Journal of minerals,metallurgy and materials 2024年第9期31卷 2062-2076页

作者： S.Abazari A.Shamsipur h.R.Bakhsheshi-Rad m.S.Soheilirad F.Khorashadizade S.S.mirhosseini Department of materials and metallurgical Engineering Amirkabir University of TechnologyTehran ***Iran Iranian National Standards Organization of hormozgan HormozganIran Advanced materials Research Center Department of Materials EngineeringNajafabad BranchIslamic Azad UniversityNajafabadIran Department of materials and metallurgical Engineering Iran University of Science and TechnologyTehranIran

magnesium(mg)alloys are gaining great consideration as body implant materials due to their high biodegradability and ***,they suffer from low corrosion resistance and antibacterial *** this research,semi-powder metallurgy followed by hot extrusion was utilized to produce the magnesium oxide@graphene nanosheets/magnesium(mgO@GNS/mg)composite to improve mechanical,corrosion and cytocompatibility *** have revealed that the incorporation of mgO@GNS nanohybrids into mg-based composite enhanced microhardness and compressive *** vitro,osteoblast cell culture tests show that using mgO@GNS nanohybrid fillers enhances osteoblast adhesion and apatite *** presence of mgO@GNS nanoparticles in the composites decreased the opening defects,micro-cracks and micro-pores of the composites thus preventing the penetration of the corrosive solution into the *** demonstrated that the mgO@GNS/mg composite possesses excellent antibacterial properties because of the combination of the release of mgO and physical damage to bacterium membranes caused by the sharp edges of graphene nanosheets that can effectively damage the cell wall thereby facilitating penetration into the bacterial lipid ***,the mgO@GNS/mg composite with high mechanical strength,antibacterial activity and corrosion resistance is considered to be a promising material for load-bearing implant applications.

关键词： metal matrix composites mgO@GNS nanohybrid strengthening mechanisms antibacterial activity biocompatibility

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New Opportunities for Neutrons in Environmental and Biological Sciences

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Frontiers of Environmental Science & Engineering 2024年第7期18卷 179-186页

作者： Alexander Johs Shuo Qian Leighton Coates Brian h.Davison James G.Elkins Xin Gu Jennifer morrell-Falvey hugh O'Neill Jeffrey m.Warren Eric m.Pierce Kenneth herwig Oak Ridge National Laboratory Oak RidgeTN37831USA

The use of neutron methods in environmental and biological sciences is rapidly emerging and accelerating with the development of new instruments at neutron user *** article,based on a workshop held at Oak Ridge National Laboratory(ORNL),offers insights into the application of neutron techniques in environmental and biological *** highlight recent advances and identify key challenges and potential future research *** include soil and rhizosphere processes,root water dynamics,plant-microbe interactions,structure and dynamics of biological systems,applications in synthetic biology and enzyme engineering,next-generation bioproducts,biomaterials and bioenergy,nanoscale structure,and fluid dynamics of porous materials in *** provide an outlook on emerging opportunities with an emphasis on new capabilities that will be enabled at the Spallation Neutron Source Second Target Station currently under design at *** mission of scientific neutron user facilities worldwide is to enable science using state-of-the-art neutron *** aim to encourage researchers in the environmental and biological research community to explore the unique capability afforded by neutrons at these facilities.

关键词： Neutrons Environment Biology Neutron imaging Neutron scattering Second Target Station(STS)

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