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Lateral femoral neck stress fractures: A case report

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World Journal of Orthopedics 2024年第9期15卷 891-901页

作者： Christiaan AJ Oudmaijer Nuno R Paulino Pereira David visser Alexander m Wakker Wout S Veltman Robbart van Linschoten Department of Surgery Division of Hepatobiliary and Transplantation SurgeryErasmus MC Transplant InstituteRotterdam 3015 GDZuid-HollandNetherlands Princess maxima Center for Pediatric Oncology Utrecht 3584 CSNetherlands Orthopaedics and Sports medicine Erasmus MCErasmus University Medical Center RotterdamRotterdam 3015 GDZuid-HollandNetherlands Department of Surgery Division of Trauma SurgeryErasmus MCErasmus University Medical Center RotterdamRotterdam 3015 GDZuid-HollandNetherlands

BACKgROUND Sport-induced injuries particularly affect young,healthy,and active ***,a popular and accessible sport,can cause a wide range of injuries,including stress *** fractures can occur during high-intensity training or competitions,especially among well-trained amateurs and professional *** diagnosis can be complicated by the typically young age,unremarkable medical history,and vital condition of the *** fractures present insidiously,and this is specifically the case with stress fractures of the femoral *** intervention is crucial to prevent progressive displacement,as this can damage the blood supply to the femoral *** SUmmARY A 30-year-old male runner presented to our outpatient clinic with persistent pain 3 weeks after running a marathon.X-ray showed a complete lateral fracture of the left femoral neck,which was treated surgically with a dynamic hip *** It is essential for healthcare providers to be vigilant for the subtle symptoms of stress fractures to ensure timely *** recognition prevents com-plication and leads to a better prognosis.

关键词： Stress fractures Atypical Femoral Neck marathon Diagnosis Case report

Analysis of the meiosis in the F_1 hybrids of Longiflorum × Asiatic(LA) of lilies(Lilium) using genomic in situ hybridization

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Journal of genetics and genomics 2008年第11期35卷 687-695页

作者： Shujun Zhou munikote S. Ramanna Richard g.E visser Jaap m. van Tuyl Institute of Landscape College of Agriculture ＆ Biotechnology Zhejiang University Hangzhou 310029 China Plant Breeding Lab Wageningen University P.O. Box 386 6700 AJ Wageningen The Netherlands

Longiflorum and Asiatic lilies of the genus Lilium of the family Liliaceae are two important groups of modem lily cultivars. One of the main trends of lily breeding is to realize introgression between these groups. With cut style pollination and embryo rescue, distant hybrids between the two groups have been obtained. However, the FI hybrids are highly sterile or some of them could produce a small number of 2n gametes, and their BC1 progenies are usually triploids. Dutch lily breeders have selected many cultivars from these BC1 progenies based on their variation. It is presumably suggested that such variation could be caused by intergenomic recombination and abnormal meiosis during gamete formation in F1 hybrids of Longiflorum × Asiatic （LA） hybrids in Lilium. Therefore, the meiotic process of ten F1 LA hybrids was cytologically investigated using genomic in situ hybridization and traditional cytological methods in the present research. The results showed that： at metaphase I, the homoeologous chromosome pairing among different F1 hybrids ranged from 2.0 to 11.4 bivalents formed by homoeologous chromosomes per pollen mother cell （PmC）, and very few multivalents, and even very few bivalents were formed by two chromosomes within one genome rather than homoeologous chromosomes in some PmCs; at anaphase I, all biva- lents were disjoined and most univalents were divided. Both the disjoined bivalents （half-bivalents） and the divided univalents （sister chromatids） moved to the opposite poles, and then formed two groups of chromosomes; because the two resulting half-bivalents retained their axes in the cell undisturbed, many crossover types, including single crossovers, three strand double crossovers, four strand double crossovers, four strand triple crossovers, and four strand multiple crossovers between the non-sister chromatids in the tetrads of bivalents, were clearly inferred by analyzing the breakpoints on the disjoined bivalents. The present investigation not only ex

关键词： Lilium genomic in situ hybridization abnormal meiosis crossover 2n gamete

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microbial starch-binding domains are superior to granule-bound starch synthase I for anchoring luciferase to potato starch granules

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Progress in Natural Science:materials International 2006年第12期16卷 1295-1299页

作者： Jean-Paul VINCKEN Luc C.J.m. SUURS Richard g.F. visser Laboratory of Plant Breeding Department of Plant Sciences Wageningen University Wageningen The Netherlands

microbial starch-binding domains (SBD) and granule-bound starch synthase I (gBSSI) are proteins which are accumulated in potato starch granules. The efficiency of SBD and gBSSI for targeting active luciferase reporter proteins to granules during starch biosynthesis was compared. gBSSI or SBD sequences were fused to the N- or C-terminus of the luciferase (LUC) gene, via an artificial Pro-Thr encoding linker sequence. The genes were introduced into an amylose-free (amf) potato mutant. It appeared that SBD was superior to gBSSI as a targeting sequence, mainly because the luciferase retained higher activity in the SBD-containing fusion proteins than in the gBSSI-containing ones.

关键词： luciferase gBSS I SBD amf potato.

management of recurrent rectal cancer:A population based study in greater Amsterdam

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World Journal of gastroenterology 2008年第39期14卷 6018-6023页

作者： Roel Bakx Otto visser Judith Josso Sybren meijer J Frederik m Slors J Jan B van Lanschot Department of Surgery Academic Medical CentreAmsterdam AZ 1105Netherlands Comprehensive Cancer Centre Amsterdam Amsterdam CX 1066Netherlands Department of Surgery Free University Medical CentreAmsterdam HV 1081Netherlands Presently at the Erasmus medical Center Rotterdam CE 3015Netherlands

AIm： To analyze, retrospectively in a populationbased study, the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision （TmE）. mETHODS： All rectal carcinomas diagnosed during 1998 to 2000 and initially treated with a macroscopically radical resection （632 patients） were selected from the Amsterdam Cancer Registry. For patients with recurrent disease, information on treatment of the recurrence was collected from the medical records. RESULTS： Local recurrence with or without clinically apparent distant dissemination occurred in 62 patients （10%）. Thirty-two patients had an isolated local recurrence. Ten of these 32 patients （31%） underwent radical re-resection and experienced the highest survival （three quarters survived for at least 3 years）. Eight patients （25%） underwent non-radical surgery （median survival 24 rno）, seven patients （22%） were treated with radio- and/or chemotherapy without surgery （median survival 15 mo） and seven patients （22%） only received best supportive care （median survival 5 too）. Distant dissemination occurred in 124 patients （20%） of whom 30 patients also had a local recurrence. The majority （54%） of these patients were treated with radio- and/or chemotherapy without surgery （median survival 15 mo）. Twenty-seven percent of these patients only received best supportive care （median survival 6 mo）, while 16% underwent surgery for their recurrence. Survival was best in the latter group （median survival 32 mo）. CONCLUSION： Although treatment options and survival are limited in case of recurrent rectal cancer after radical local resection obtained with TmE, patients can benefit from additional treatment, especially if a radical resection is feasible.

关键词： Rectal cancer Total mesorectal excision Local recurrence Relative survival

Prior-based Bayesian information criterion

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Statistical Theory and Related Fields 2019年第1期3卷 2-13页

作者： m.J.Bayarria James O.Berger Woncheol Jang Surajit Ray Luis R.Pericchi Ingmar visser Department of Statistics and Operations Research University of ValenciaValenciaSpain Department of Statistical Science Duke UniversityDurhamNCUSA Department of Statistics Seoul National UniversitySeoulKorea School of mathematics and Statistics University of GlasgowGlasgowUK Department of mathematics University of Puerto RicoSan JuanPuerto Rico Department of Psychology University of AmsterdamAmsterdamNetherlands

We present a new approach to model selection and Bayes factor determination,based on Laplaceexpansions(as in BIC),which we call Prior-based Bayes Information Criterion(PBIC).In thisapproach,the Laplace expansion is only done with the likelihood function,and then a suitableprior distribution is chosen to allow exact computation of the(approximate)marginal likelihoodarising from the Laplace approximation and the *** result is a closed-form expression similar to BIC,but now involves a term arising from the prior distribution(which BIC ignores)andalso incorporates the idea that different parameters can have different effective sample sizes(whereas BIC only allows one overall sample size n).We also consider a modification of PBIC whichis more favourable to complex models.

关键词： Bayes factors model selection Cauchy priors consistency effective sample size Fisher information Laplace expansions robust priors

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DB2通用数据库自学教程 1

The ability to manipulate ROS metabolism in pepper may affect aphid virulence

1999年

作者：（美）Susan m.visser 王晓冬译

本书全面地讲述了DB2通用数据库5.0版所讨论如何满足从Web访问安装、配置、日常管理、命令、性能调整和错误诊断及解决方法，到深入讨论如何满足从Web访问数据库中的并行处理，并且通过一些实例和专家提供的技巧教你如何在最短的时间内... 详细信息

ISBN: (纸本)7900617922

本书全面地讲述了DB2通用数据库5.0版所讨论如何满足从Web访问安装、配置、日常管理、命令、性能调整和错误诊断及解决方法，到深入讨论如何满足从Web访问数据库中的并行处理，并且通过一些实例和专家提供的技巧教你如何在最短的时间内了DB2技术，创建、管理和优化DB2数据库。

关键词：关系型数据库数据库管理系统,DB2

来源：畅想之星图书光盘版（南... 评论

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Horticulture Research 2020年第1期7卷 2720-2732页

作者： mengjing Sun Roeland E.Voorrips martijn van Kaauwen Richard g.Fvisser Ben Vosman Plant Breeding Wageningen University&ResearchP.O.Box 3866700 AJ WageningenNetherlands

myzus persicae has severe economic impact on pepper(Capsicum)***,we identified two populations of ***,NL and SW,that were avirulent and virulent,respectively on *** accession *** transcriptomics approach used in the current study,which is the first study to explore the pepper−aphid interaction at the whole genome gene expression level,revealed genes whose expression is differentially regulated in pepper accession PB2013071 upon infestation with these *** *** NL population induced ROS production genes,while the SW population induced ROS scavenging genes and repressed ROS production *** also found that the SW population can induce the removal of ROS which accumulated in response to preinfestion with the NL population,and that preinfestation with the SW population significantly improved the performance of the NL *** paper supports the hypothesis that *** can overcome the resistance in accession PB2013071 probably because of its ability to manipulate plant defense response especially the ROS metabolism and such ability may benefit avirulent conspecific aphids.

关键词： metabolism pepper overcome

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90年代传染病的治疗

药学进展 1992年第3期16卷 173-177页

作者： m.Rozenberg-Arska m.R.visser 玉荣肖霞

虽然抗微生物药已使用50多年了,但仍有许多患者死于感染。在传染病的预防、治疗方面和研制、开发作用更强、更安全、广谱的抗微生物药方面均已取得了显著的进展。在增强和恢复人体对致病性或条件致病性微生物的免疫应答方面也作了大量... 详细信息

虽然抗微生物药已使用50多年了,但仍有许多患者死于感染。在传染病的预防、治疗方面和研制、开发作用更强、更安全、广谱的抗微生物药方面均已取得了显著的进展。在增强和恢复人体对致病性或条件致病性微生物的免疫应答方面也作了大量的工作。那么,为什么某些抗微生物药对严重感染的患者缺乏疗效?对这样一些感染我们该如何进行治疗?

关键词：传染病抗微生物疗法免疫疗法

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利用gBSSI和SBD作为“锚”将荧光素酶定位到淀粉粒中效果的比较

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自然科学进展 2006年第6期16卷 679-683页

作者：季勤 Jean-Paul Vincken Krit Raemakers Luc C.J.m.Suurs Richard g.F.visser 淮阴师范学院生物系淮安223300 Laboratory of Plant Breeding Department of Plant SciencesWageningen UniversityWageningenThe Netherlands

利用马铃薯淀粉粒结合型淀粉合成酶Ⅰ(gBSSI)作为“锚”,在马铃薯淀粉粒形成时将荧光素酶(LUC)定位到淀粉粒中．并对gBSSI／LUC重组蛋白质在转基因淀粉粒中的定位与积累、重组蛋白质中gBSSI与淀粉粒的亲和性以及荧光素酶的活性等进行了... 详细信息

利用马铃薯淀粉粒结合型淀粉合成酶Ⅰ(gBSSI)作为“锚”,在马铃薯淀粉粒形成时将荧光素酶(LUC)定位到淀粉粒中．并对gBSSI／LUC重组蛋白质在转基因淀粉粒中的定位与积累、重组蛋白质中gBSSI与淀粉粒的亲和性以及荧光素酶的活性等进行了分析．结果表明,gBSSI／ LUC重组蛋白质在马铃薯淀粉粒中获得了特异性表达,但与以微生物的淀粉粒结合结构域(SBD) 作为“锚”的SBD／LUC重组蛋白质相比较,它与淀粉粒的亲和性以及荧光素酶的活性均下降．由此认为,在淀粉粒形成过程中,利用SBD作为“锚”将荧光素酶蛋白质定位到淀粉粒中的效果要优于gBSSI．

关键词：荧光素酶 gBSSI SBD amf马铃著

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