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Frontiers of Chemical Science and Engineering 2020年第5期14卷 793-801页

作者： Chenggang Qiu Alei Zhang sha Tao Kang Li Kequan Chen Pingkai Ouyang College of Biotechnology and Pharmaceutical Engineering Nanjing Tech UniversityNanjing 211800China State Key Laboratory of materials-Oriented Chemical Engineering Nanjing Tech UniversityNanjing 211800China

Strain QCG of the aerobic bacteria Bacillus cereus is capable of producing l-naphthol from naphtha-lene,this strain was first isolated and characterized in this *** QCG was mutagenized to enhance l-naphthol production,using atmospheric and room temperature plasma(ARTP)***,a microbial clone screening system was used to accelerate the ***,a novel color-mediated high-throughput screening using 4-aminoantipyrine was performed to screen *** optimal mutant strain QCG4 produced 19.58土0.34 mg·L-1-naphthol from naphthalene that was 47.32%higher than that of the original strain(13.29+0.28 mg·L-1).In addition,the optimal conditions for l-naphthol production via whole-cell catalysis of strain QCG4 were determined to be an OD600 of40,150 mg.L I naphthalene,and 7.5%dimethyl formamide as a co-solvent at pH 7.5 and 26℃ for 3 h,resulting in 41.18士0.12 mg·L-l-naphthol,i.e.,the mutant strain produces a 2.1-fold higher yield compared to the original strain.

关键词： Bacillus cereus QCG naphthalene 1-naphthol ARTP mutagenesis high-throughput screening 4-aminoan-tipyrine

Agar-derived nitrogen-doped porous carbon as anode for construction of cost-effective lithium-ion batteries

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中国化学快报:英文版 2023年第8期34卷 370-375页

作者： Tong Wang Jingquan sha Wenwen Wang Yuhan Ji Zhi-ming Zhang Institute for New Energy materials&Low Carbon Technologies School of Chemistry and Chemical EngineeringTianjin University of TechnologyTianjin 300384China School of Chemistry Chemical Engineering and MaterialsJining UniversityQufu 273100China

Balancing cost and performance of porous carbon(PC)as anode for lithium-ion battery(LIBs)is the key to effectively promote commercial ***,low-cost N-doped PC(NPC-Ts,T=600,750 and 900°C)were facilely prepared in batches via one-pot pyrolysis of agar with different carbonization *** NPC-750 with specific surface area of 2914 m^(2)/g and N content of 2.84%exhibits an ultrahigh reversible capacity of 1019 mAh/g at 0.1 A/g after 100 cycles and 837 mAh/g at 1 A/g after 500 ***,the resulting LIBs exhibit an ultrafast charge-discharge feature with a remarkable capacity of 281 mAh/g at 10 A/g and a superlong cycle life with a capacity retention of 87%after 5000 cycles at 10 A/*** with LiFePO_(4)cathode,the fabricated lithium-ion full cells possess high capacity,excellent rate and cycling performances(125 mAh/g at 100 mA/g,capacity retention of 95%,after 220 cycles),highlighting the practicability of this NPC-750 as the anode materials.

关键词： Agar Porous carbon N-doping Anode Lithium-ion battery

Effects of land-use types on the vertical distribution of fractions of oxidizable organic carbon on the Loess Plateau, China

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Journal of Arid Land 2016年第2期8卷 221-231页

作者： SUN Caili XUE sha CHAI Zongzheng ZHANG Chao LIU Guobin Institute of Soil and Water Conservation Northwest A&F University Institute of Soil and Water Conservation Chinese Academy of Sciences and Ministry of Water Resources College of Forestry Northwest A&F University

The oxidizability of soil organic carbon （SOC） influences soil quality and carbon sequestration. Four fractions of oxidizable organic carbon （very labile （C1）, labile （C2）, less labile （C3） and non-labile （C4）） reflect the status and composition of SOC and have implications for the change and retention of SOC. Studies of the fractions of oxidizable organic carbon （OC） have been limited to shallow soil depths and agroecosystems. How these fractions respond at deep soil depths and in other types of land-use is not clear. In this study, we evaluated the vertical distributions of the fractions of oxidizable organic carbon to a soil depth of 5.0 m in 10 land-use types in the Zhifanggou Watershed on the Loess Plateau, China. Along the soil profile, C1 contents were highly variable in the natural grassland and shrubland I （Caragana microphylla）, C2 and C4 contents were highly variable in the natural grassland and two terraced croplands, respectively, and C3 contents varied little. Among the land-use types, natural grassland had the highest C1 and C2 contents in the 0-0.4 m layers, followed by shrubland I in the 0-0.1 m layer. Natural grassland had the highest C4 contents in the 1.0-4.5 m layers. Natural grassland and shrubland I thus contributed to improve the oxidizability of SOC in shallow soil, and the deep soil of natural grassland has a large potential to sequester SOC on the Loess Plateau.

关键词： Iand-use types deep soil oxidizable organic-carbon fractions Loess Plateau

Uncertainty quantification for stochastic dynamical systems using time-dependent stochastic bases

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Applied mathematics and mechanics(English Edition) 2019年第1期40卷 63-84页

作者： Jinchun LAN Qianlong ZHANG sha WEI Zhike PENG Xinjian DONG Wenming ZHANG State Key Laboratory of mechanical System and Vibration School of Mechanical EngineeringShanghai Jiao Tong University

A novel method based on time-dependent stochastic orthogonal bases for stochastic response surface approximation is proposed to overcome the problem of significant errors in the utilization of the generalized polynomial chaos(GPC) method that approximates the stochastic response by orthogonal polynomials. The accuracy and effectiveness of the method are illustrated by different numerical examples including both linear and nonlinear problems. The results indicate that the proposed method modifies the stochastic bases adaptively, and has a better approximation for the probability density function in contrast to the GPC method.

关键词： uncertainty quantification stochastic response surface approximation timedependent orthogonal bases polynomial chaos

超声造影联合血清Ficolin-3,FOXm1对2型糖尿病下肢动脉病变的诊断价值分析

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四川医学 2024年第9期45卷 983-988页

作者：何兰芳康佳沙晓溪吕德康彧成都中医药大学附属医院超声医学科内分泌科四川成都610075

目的超声造影联合血清纤维胶凝蛋白-3(Ficolin-3)、叉头框蛋白m1(FOXm1)对2型糖尿病(T2Dm)下肢动脉病变的诊断价值分析。方法选取2022年2月至2023年2月我院收治的T2Dm患者114例,以下肢动脉血管造影检查为金标准,将患者分为下肢动脉病变... 详细信息

目的超声造影联合血清纤维胶凝蛋白-3(Ficolin-3)、叉头框蛋白m1(FOXm1)对2型糖尿病(T2Dm)下肢动脉病变的诊断价值分析。方法选取2022年2月至2023年2月我院收治的T2Dm患者114例,以下肢动脉血管造影检查为金标准,将患者分为下肢动脉病变组23例(病变组)和无下肢动脉病变组91例(T2Dm组),另选取同期于本院进行体检的健康志愿者91例为对照组。对患者及健康志愿者进行血清Ficolin-3、FOXm1及超声造影检查;ROC曲线分析血清Ficolin-3、FOXm1对T2Dm下肢动脉病变的诊断价值;采用四格表法分析血清Ficolin-3、FOXm1、超声造影及3项联合对T2Dm下肢动脉病变的诊断价值。结果病变组、T2Dm组血清Ficolin-3水平显著高于对照组,且病变组血清Ficolin-3水平显著高于T2Dm组(均Pm组血清FOXm1水平显著低于对照组,且病变组血清FOXm1水平显著低于T2Dm组(均Pm下肢动脉病变的曲线下面积为0.868,敏感度为86.96%,特异度为75.82%,最佳截断值为35.12μg/ml;血清FOXm1诊断T2Dm下肢动脉病变的曲线下面积为0.854,敏感度为82.61%,特异度为78.02%,最佳截断值为0.57;血清Ficolin-3、FOXm1检查结果与金标准均具有中度一致性(Kappa=0.480、0.481,均Pm下肢动脉病变的阳性检出率为73.91%,与金标准具有较高一致性(Kappa=0.631,Pm1单独诊断,差异均有统计学意义(均Pm1联合超声造影检查在T2Dm下肢动脉病变诊断中的应用价值较高,进一步提升了诊断的敏感度、准确度,减少了误诊率。

关键词：超声造影纤维胶凝蛋白-3 叉头框蛋白m1 2型糖尿病下肢动脉病变

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侧风环境下悬挂式轨道列车气动特性研究

五邑大学学报（自然科学版） 2024年第1期38卷 36-44页

作者：高宏波李志伟黄莎五邑大学轨道交通学院广东江门529020 江门市五邑大学轨道交通智能运维与应急管理重点实验室广东江门529020

为了研究侧风对悬挂式轨道列车运行安全的影响,本文以时速80 km/h运行的某型悬挂式轨道列车为研究对象,采用三维、粘性、不可压缩N-S方程以及标准双方程k-ε湍流模型进行数值仿真,探究在20 m/s、30 m/s、40 m/s风速下不同风向角的悬挂... 详细信息

为了研究侧风对悬挂式轨道列车运行安全的影响,本文以时速80 km/h运行的某型悬挂式轨道列车为研究对象,采用三维、粘性、不可压缩N-S方程以及标准双方程k-ε湍流模型进行数值仿真,探究在20 m/s、30 m/s、40 m/s风速下不同风向角的悬挂式轨道列车周围流场和气动载荷特性.研究结果表明,随着风速的增大,列车的升力、侧向力、侧滚力矩绝对值均逐渐增大;随着侧风风向角的增大,列车的表面压力系数、升力、侧向力、侧滚力矩均呈现先增后减小的趋势;头车、中间车、尾车气动载荷出现峰值的风向角略有不同;倾覆力矩主要由侧向力主导受升力影响不大;编组中头车最容易在强风中发生较大横向位移,引发车体晃动.本文研究结果可为悬挂式轨道列车的安全运行提供理论支持.

关键词：悬挂式列车侧风气动特性数值模拟

巨龙铜矿地应力对大断面巷道稳定性与岩爆倾向性数值模拟

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矿产保护与利用 2024年第2期44卷 52-57页

作者：沙仙武陈才贤李佳建西藏巨龙铜业有限公司西藏拉萨850200 北京科技大学北京100083

分析矿山深部巷道稳定性及岩爆倾向性对于矿山安全建设具有重要意义。以巨龙铜矿大断面深埋长巷道为研究对象,利用数值模拟手段探究了青藏高原地应力影响下环形排水巷稳定性,分析了巷道掘进后岩爆倾向性。结果表明,环形排水巷道围岩内... 详细信息

分析矿山深部巷道稳定性及岩爆倾向性对于矿山安全建设具有重要意义。以巨龙铜矿大断面深埋长巷道为研究对象,利用数值模拟手段探究了青藏高原地应力影响下环形排水巷稳定性,分析了巷道掘进后岩爆倾向性。结果表明,环形排水巷道围岩内应力以水平应力为主,最大主应力为32 mPa,在16段排水巷道中,应力主要集中于巷道DE、EF、DG段。巷道围岩水平位移大于垂直位移,环形排水巷道最大位移以m点为中心向四周扩散。Gm段、HL段、KN段巷道围岩均发生了较大变形,对于该区域巷道应加强支护。巷道DE、EF、DG段最大弹性应变达到1.01×10^(5) J/m^(3),呈现出岩爆倾向,可通过减小开挖进尺削弱岩体局部应力集中。现场监测表明模拟结果可靠。该研究结果为巨龙铜矿环形排水巷施工及地压灾害防控提供了理论参考。

关键词：巨龙铜矿地应力大断面巷道稳定性岩爆倾向性数值模拟

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印制线路板化学镍金镍腐蚀研究

印制电路信息 2024年第S1期32卷 183-194页

作者：沙雷马国强刘志平深南电路股份有限公司广东深圳518100

本文对印制线路板(PCB)化学镍金的镍腐蚀进行了研究,探讨了镍腐蚀的形成机理,结合以往的研究,通过本次研究实验发现金厚对镍腐蚀有一定的影响,但是镍槽的活性才是引起镍腐蚀最关键的影响因子。作者主要从镍缸活性探究镍腐蚀的问题,研究... 详细信息

本文对印制线路板(PCB)化学镍金的镍腐蚀进行了研究,探讨了镍腐蚀的形成机理,结合以往的研究,通过本次研究实验发现金厚对镍腐蚀有一定的影响,但是镍槽的活性才是引起镍腐蚀最关键的影响因子。作者主要从镍缸活性探究镍腐蚀的问题,研究了活化槽、镍缸药水稳定性(开缸剂m、药水添加)、有机物溶出对化学镍金镍腐蚀的影响,最后结合实际的生产经验给出镍腐蚀相应的控制方法。

关键词：印制线路板化学镍金镍腐蚀控制方法

Does dyslipidemia worsen the hearing level in diabetics?

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Journal of Otology 2017年第4期12卷 198-201页

作者： Pratap Deepika A. Rajeshwary shastri U sha m.K. Goutham sharma Raghav Dept of Otorhinolaryngology KSHEMA Nitte University Mangalore 575018 India Dept of Audiology and Speech Language Pathology Nitte Institute of Speech and Hearing Mangalore 575018 India Dept of medicine KSHEMA Nitte University Mangalore 575018 India

Objective: To identify the effect of dyslipidemia on auditory function detected by Pure Tone Audiometry. To check if dyslipidemia worsens the hearing level in ***: This was a comparative study where 120 subjects between the age group of 20 and 50 years underwent pure tone audiometry, lipid profile and blood sugars. Group 1 consisted of 30 subjects with type 2 diabetes and dyslipidemia; Group 2 had 30 subjects with isolated diabetes;Group 3 had 30 with isolated dyslipidemia and Group 4 included 30 normal subjects as ***: Significant hearing loss was seen only in the group with isolated diabetes(63%). The most common type of hearing loss was high frequency sensorineural hearing loss. When comparison was made between the combinations of different lipid profiles, no association was found to the level of ***: Diabetics are more prone to high frequency hearing loss. Altered lipid profile has no role in causing hearing loss.

关键词： Dyslipidemia Diabetes Pure tone audiometry

Circulating tumor cells with epithelial-mesenchymal transition markers as potential biomarkers for the diagnosis of lung cancer

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World Journal of Clinical Cases 2021年第12期9卷 2721-2730页

作者： sha-sha Jiang Chun-Guo mao Yong-Geng Feng Bin Jiang shao-Lin Tao Qun-You Tan Bo Deng Department of Thoracic Surgery Institute of Surgery ResearchDaping HospitalArmy Medical UniversityChongqing 400042China

BACKGROUND Circulating tumor cells(CTCs) can be clustered into three subtypes according to epithelial-mesenchymal transition(EmT) markers: CTCs with epithelial markers(E-CTCs), CTCs with mesenchymal markers(m-CTCs), and CTCs with both markers(E&m-CTCs). CTC detection has clinical implications in the diagnosis of lung cancer(LC).AIm To clarify the diagnostic value of CTCs categorized by EmT markers in *** The study included 106 patients with lung adenocarcinoma, including 42 groundglass opacities(GGO) and 64 solid lesions, who underwent surgery between July 2015 and December 2019. Eleven patients with benign tumors and seventeen healthy controls were included. CTCs in peripheral blood and associated EmT markers were detected preoperatively using the CanPatrol Tm technique. The diagnostic power of CTCs for discriminating LC cases from controls was analyzed by the receiver operating characteristic(ROC) curve. The CytoploRare technique was used in 20 cases and 18 controls for validation, and Kappa values were calculated to evaluate consistency between *** Of the 106 LC cases, 94(89.6%) had at least one CTC. CTCs were detectable in 35(83.3%) of 42 GGO cases. Total CTCs and E&m-CTCs were significantly more frequent in LC cases than in benign or healthy controls. The proportion of mCTCs plus E&m-CTCs increased gradually from healthy controls, to benign controls, to LC cases. The area under the ROC curve of total CTCs and E&m-CTCs was > 0.8 and > 10.75, respectively. The combined sensitivity of total-CTCs and E&m-CTCs was 85.85% for LC patients(80.95% for GGO patients) and the specificity was 78.57%.The Kappa value was 0.415,indicating relative consistency between CanPatrol Tm and *** CTC detection is valuable for distinguishing LC from controls,and particularly E&m-CTC detection warrants further study.

关键词： Circulating tumor cells Epithelial-to-mesenchymal transition Diagnosis Lung cancer Ground-glass opacities CanPatrol