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The relationship between controllability, optimal testing resource allocation, and incubation-latent period mismatch as revealed by COVID-19

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Infectious Disease modelling 2023年第2期8卷 514-538页

作者： Jeffery Demers William F.Fagan Sriya Potluri Justin m.calabrese Center for Advanced Systems Understanding(CASUS) Helmholtz-Zentrum Dresden-Rosendorf(HZDR)G€orlitzGermany Dept.of Biology University of MarylandCollege ParkMDUSA Dept.of Ecological modelling Helmholtz Centre for Environmental Research-UFZLeipzigGermany

The severe shortfall in testing supplies during the initial COVID-19 outbreak and ensuing struggle to manage the pandemic have affirmed the critical importance of optimal supplyconstrained resource allocation strategies for controlling novel disease *** address the challenge of constrained resource optimization for managing diseases with complications like pre-and asymptomatic transmission,we develop an integro partial differential equation compartmental disease model which incorporates realistic latent,incubation,and infectious period distributions along with limited testing supplies for identifying and quarantining infected *** model overcomes the limitations of typical ordinary differential equation compartmental models by decoupling symptom status from model compartments to allow a more realistic representation of symptom onset and presymptomatic *** analyze the influence of these realistic features on disease controllability,we find optimal strategies for reducing total infection sizes that allocate limited testing resources between‘clinical’testing,which targets symptomatic individuals,and‘non-clinical’testing,which targets non-symptomatic *** apply our model not only to the original,delta,and omicron COVID-19 variants,but also to generically parameterized disease systems with varying mismatches between latent and incubation period distributions,which permit varying degrees of presymptomatic transmission or symptom onset before *** find that factors that decrease controllability generally call for reduced levels of non-clinical testing in optimal strategies,while the relationship between incubation-latent mismatch,controllability,and optimal strategies is *** particular,though greater degrees of presymptomatic transmission reduce disease controllability,they may increase or decrease the role of nonclinical testing in optimal strategies depending on other disease factors like transmissibility

关键词： Testing quarantine control Optimal resource allocation Presymptomatic transmission Latent period Incubation period Age of infection

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乳腺癌病人乳腺mRI中的肌肉质量评估:CT腰肌面积与mRI胸肌面积的比较

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国际医学放射学杂志 2019年第2期42卷 248-249页

作者： F.Rossi F.Valdora E.Barabino m.calabrese A.S.Tagliafico 李爽(译) 赵世华(校) Department of Health Sciences DISSAL-University of GenovaVia Pastore116138 GenoaItaly 不详

目的在乳腺癌病人中评价CT成像的腰肌面积(TPA)与mR成像的胸肌面积(PmA)的相关性。方法该回顾性研究经机构伦理委员会批准,参与研究的女性均签署了书面知情同意书。

关键词：乳腺癌肌肉质量 mRI CT

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臂丛神经mR成像:3.0 T mR DTI相关测量与纤维示踪技术的精确性及可重复性

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国际医学放射学杂志 2011年第5期 508-509页

作者： A.Tagliafico m.calabrese m.Puntoni D.Pace G.Baio C.E.Neumaier 蔡兆诚 Department of Radiology National Institute for Cancer Research(IST)

目的对无臂丛神经病理改变的志愿者进行3.0 T mRI检查,评估DTI相关测量与纤维示踪技术(FT)的组内与组间可重复性。方法本研究经机构伦理委员会批准并获得

关键词：扩散张量成像臂丛神经可重复性各向异性分数表观扩散系数 mRI 最小检测差异

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多发性硬化mR扩散张量成像的脑皮质异常:为期3年的纵向研究

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国际医学放射学杂志 2012年第1期 86-86页

作者： m.calabrese F.Rinaldi D.Seppi A.Favaretto L.Squarcina I.mattisi 夏艺 Department of Neurosciences Multiple Sclerosis Centre of Veneto Region-First Neurology ClinicUniversity Hospital of PadovaVia Giustiniani 535128 PaduaItaly

目的评价扩散张量成像联合双反转恢复序列是否能够发现多发性硬化(mS)病人脑皮质的结构变化。材料与方法经本地伦理委员会批准并获得知情同意后,纳入168

关键词：多发性硬化病变病人脑皮质 EDSS mR 纵向研究扩散张量

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超声引导下经皮注射曲安奈德对隆胸和乳房再造术后病人乳房纤维包膜挛缩的治疗

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国际医学放射学杂志 2011年第3期 296-296页

作者： L.m.Sconfienza C.murolo S.Callegari m.calabrese E.Savarino P.Santi 郭丽君 Unità di Radiologia IRCCS Policlinico San DonatoVia Morandi 3020097 San Donato MilaneseMilanoItaly

目的评价隆胸/乳房再造术后病人经超声(US)引导治疗乳房纤维包膜挛缩(CC)的效果。材料与方法 25例4级CC病人经US引导下植入体周围注射曲安奈德治疗。US

关键词：超声引导包膜萎缩乳腺曲安奈德

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Unidirectional reflection from an integrated“taiji”microresonator

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Photonics Research 2020年第8期8卷 1333-1341页

作者： A.calabrese F.RAmIRO-mANZANO H.m.PRICE S.BIASI m.BERNARD m.GHULINYAN I.CARUSOTTO L.PAVESI Laboratoire de Physique de l’Ecole Normale Superieure ENSParis Sciences et LettresCNRSUniversitéde Paris75005 ParisFrance Instituto de Tecnologı´a Quı´mica(CSIC-UPV).Av.de los Naranjos 46022 ValenciaSpain School of Physics and Astronomy University of BirminghamEdgbastonBirmingham B152TTUK Nanoscience Laboratory Dipartimento di FisicaUniversity of TrentoVia Sommarive 1438123 Povo(TN)Italy Centre for materials and microsystems Fondazione Bruno KesslerVia Sommarive 1838123 Povo(TN)Italy INO-CNR BEC Center and Department of Physics University of TrentoVia Sommarive 1438123 PovoItaly

We study light transmission and reflection from an integrated microresonator device,formed by a circular microresonator coupled to a bus waveguide,with an embedded S-shaped additional crossover waveguide element that selectively couples counter-propagating modes in a propagation-direction-dependent *** overall shape of the device resembles a“taiji”symbol,hence its *** Lorentz reciprocity is preserved in transmission,the peculiar geometry allows us to exploit the non-Hermitian nature of the system to obtain high-contrast unidirectional reflection with negligible reflection for light incident in one direction and a significant reflection in the opposite direction.

关键词： hence negligible crossover

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Self-assembled formation of long, thin, and uncoalesced GaN nanowires on crystalline TiN films

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Nano Research 2018年第1期11卷 565-576页

作者： David van Treeck Gabriele calabrese Jelle J. W. Goertz Vladimir m. Kaganer Oliver Brandt Sergio Fernandez-Garrido, Lutz Geelhaar PauI-Drude-lnstitut f~r Festk6rperelektronik Leibniz-lnstitut im Forschungsverbund Berlin e.V. Hausvogteiplatz 5-7 I 0117 Berlin Germany

We investigate in detail the self-assembled nucleation and growth of vertically oriented GaN nanowires by molecular beam epitaxy on crystalline TiN films. We demonstrate that this type of substrate allows for the growth of long and thin GaN nanowires that do not suffer from coalescence, a problem common to the growth on Si and other substrates. Only beyond a certain nanowire length that depends on the nanowire density and exceeds here 1.5 bun, coalescence takes place by bundling, i.e. the same process as on Si. By analyzing the nearest neighbor distance distribution, we identify the diffusion-induced repulsion of neighboring nanowires as the main mechanism limiting nanowire density during nucleation on TiN. Since on Si the final density is determined by shadowing of the impinging molecular beams by existing nanowires, it is the difference in adatom surface diffusion that enables the formation of nanowire ensembles with reduced density on TiN. These nanowire ensembles combine properties that make them a promising basis for the growth of core-shell heterostructures.

关键词： nanocolumn gallium nitride nucleation metal substrate coalescence core-shell

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Titanium-coated polypropylene mesh as innovative bioactive material in conservatives mastectomies and pre-pectoral breast reconstruction

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Bioactive materials 2021年第12期6卷 4640-4653页

作者： Pietro Gentile marco Bernini Lorenzo Orzalesi Silvia Sordi Icro meattini Francesca Lessi Ashutosh Kothari Claudio calabrese Department of Surgical Science University of Rome“Tor Vergata”Rome00133Italy Breast Surgery Breast UnitOncology DepartmentCareggi University Hospital50134FlorenceItaly Department of Experimental and Clinical Biomedical Sciences“m.Serio” University of Florence Radiation Oncology Unit-OncologyCareggi University HospitalFlorenceItaly Fondazione Pisana per la Scienza onlus Pisa 56122Italy Breast Surgery Unit Guy’s HospitalGuy’s and St.Thomas’NHS Foundation TrustLondonUnited Kingdom San Rossore Breast Unit Pisa 56122Italy

Breast reconstruction is rapidly evolving,thanks to the growing acceptance of synthetic meshes as innovative biomaterials.276 patients undergoing mastectomy(total of 328 mastectomies)were analyzed in a retrospective observational study to evaluate the pre-pectoral immediate breast reconstruction(IBR)using an implant wrapped with Titanium-Coated Polypropylene mesh(TCPm)*** treated with tissue expander(TE),equally placed pre-pectorally(and wrapped with the same TCPm in 74.3%of the control group’breasts).163 patients,of the study group(SG),underwent mastectomy and pre-pectoral IBR with implant wrapped with TCPm,in a one-step surgery,called direct-to-implant technique(DTI),while 113 patients control group(CG)underwent mastectomy and *** technique has been performed in 192 breasts of the SG while TE procedure in 136 breasts of the *** BREAST-Q questionnaire has been provided before the treatment and 2 years *** scale has been used to evaluate capsular ***,surgical,and aesthetic outcomes along with BREAST-Q scores were ***,a histologic evaluation was conducted in 11 capsules’samples randomly chosen(6 derived from SG patients and 5 derived from CG).Complications were recorded in 43 cases(29SG-14CG):8 skin-nipple necrosis(5SG-3CG),8 wound dehiscence(6SG-2CG),3 hematomas(1SG-2CG),and 24 infections(8SG-16CG).Grade IV capsular contracture was detected in 9 breasts(1SG-8CG),whereas 254 breasts were grade I(110SG-144CG),33(10SG-23CG)grade II,and 32(4SG-28CG)grade *** wrinkling was detected in 18 cases(10SG-8CG)after 30 *** local tumor recurrence rate was 5.8%.Three recurrences were on the nipple-areola complex(1.9%).SG patients showed significantly higher rates in the BREAST-Q overall Satisfaction with Outcome(74.1),overall Satisfaction with Breasts(69.1),Psychosocial Well-being(81.9),and Sexual Well-being(63.1),versus CG’s patients(pmal tissue repair with

关键词： mastectomy Pre-pectoral breast reconstruction Titanium-coated polypropylene mesh Immediate breast reconstruction

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Friction of Alloys at High Temperature

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Journal of materials Science & Technology 1994年第5期10卷 313-320页

作者： m.B.Peterson (Wear Sciences, 925 mallard Circle, Arnold maryland 21012, USA)(To whom correspondence should be addressed)S.J.calabrese (Rensselaer Polytechnic Institute, Troy, NY, USA)Shizhuo LI and Xiaoxia JIANG (Institute of metal Research, Chinese Acad Wear Sciences Arnold United States

A brief review is given about the friction and wear properties of high temperature alloys. Above a critical temperature, if the oxide becomes ductile, it will flow over the surface and prevent metal-to-metat contact. In order to study the tribology of oxide lubrication. a series of tests were carried out using Cu(ReO4)2 as a lubricant. The effects of time. Surface finish. substrates. load and temperature were investigated. A mechanism of lubrication is proposed in which the surface slip predominates along with mechanical attachment of oxide to the surface.

关键词： Re Cu Friction of Alloys at High Temperature ADA Ni

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Antibiotics and probiotics in treatment of inflammatory bowel disease

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World Journal of Gastroenterology 2006年第21期12卷 3306-3313页

作者： Paolo Gionchetti Fernando Rizzello Karen m Lammers Claudia morselli Lucia Sollazzi Samuel Davies Rosy Tambasco Carlo calabrese massimo Campieri Departmentof Internal medicine and Gastroenterology University of Bologna BolognaItaly

许多试验性、临床的观察建议肠的微植物群在煽动性的肠疾病(IBD ) 的致病起一个潜在的作用。用抗菌素或职业人员生命学的钠内容的操作代表一种潜在地有效的治疗学的选择。可得到的研究不在 ulcerative (UC ) 支持抗菌素的使用。抗菌素... 详细信息

许多试验性、临床的观察建议肠的微植物群在煽动性的肠疾病(IBD ) 的致病起一个潜在的作用。用抗菌素或职业人员生命学的钠内容的操作代表一种潜在地有效的治疗学的选择。可得到的研究不在 ulcerative (UC ) 支持抗菌素的使用。抗菌素在对待是有效的腐败 Crohn 的疾病(CD ) 的复杂并发症但是他们主要治疗是更争论的使用，尽管这条途径经常并且成功地在临床的实践被采用。有证据关於生命的治疗可以是的那个职业人员在预防和处理有效对中等 UC 温和。相反，成功的学习数据的缺乏目前预防在 CD 的处理的专业版生命学的普遍使用。抗菌素和职业人员生命学看起来在 pouchitis 的处理和预防起一个有益的作用，进一步的审判被保证充分确定他们的临床的功效。

关键词：抗生素肠炎治疗临床

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