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From α,β-Epoxyaldehydes to Peptidonucleosides and Iminosugars

复旦学报(自然科学版) 2005年第5期44卷 648-649页

作者： m.baltas Y.Génisson m.Collet T.Ayad V.Faugeroux Synthèse et Physicochimie de molécules d'Intérêt Biologique UmR CNRS 5068 UniversitéPaul Sabatier118 route de NarbonneF-31062 Toulouse cedex 04France

1 Introduction The primary objectives of the group“Natural products and bioactive molecules”,are the development of synthetic methods,their application in the elaboration of natural compounds and analogues and the translation of this know-how through an integrated approach to the identification of attractive leads in order to confront some of the major diseases in the developed and developing countries.

关键词： epoxyaldehydes regioselectivity lactones aminoalcohols fluoronucleosides

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GIS-based optimisation of the hydrometeorological network in Greece

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International Journal of Digital Earth 2009年第2期2卷 171-185页

作者： E.A.baltas m.A.mimikou Department of Hydraulics Soil Science and Agricultural EngineeringSchool of AgricultureAristotle University of Thessaloniki54006Greece Department of Water Resources and Environmental Engineering National Technical University of AthensGreece

The operation of a network of hydrometeorological stations constitutes basic infrastructure for the management of water *** the increased need for rational water management in Greece,there is not a single network of hydrometeorological *** State Services have established sectional networks of limited coverage,resulting in many *** study aims at the optimisation of the existing network,using GIS *** optimum network of hydrometeorological stations is designed,which constitutes the base for the optimisation of the present *** optimum network consists of 1379 hydrometeorological stations and is based on the guidelines of international *** uniform spatial distribution of the stations and criteria concerning the selection of the appropriate site,such as the low terrain slope,easy accessibility and proximity to special interest points,were of special importance for its ***,only the 20%of the existing stations remain at their locations and are included in the optimised *** rest of the stations should be redistributed according to the proposed sites of the optimum network.

关键词： hydrometeorological network station GIS optimisation

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Data Driven modelling of Coronavirus Spread in Spain

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Computers, materials & Continua 2020年第9期64卷 1343-1357页

作者： G.N.baltas F.A.Prieto m.Frantzi C.R.Garcia-Alonso P.Rodriguez Loyola Institute of Science and Technology Universidad Loyola AndalucíaSeville41704Spain Department of Biomarker Research Mosaiques Diagnostics GmbHHannover30659Germany Renewable Electrical Energy Systems Technical University of CataloniaTerrassa08222Spain

During the late months of last year,a novel coronavirus was detected in Hubei,*** virus,since then,has spread all across the globe forcing Word Health Organization(WHO)to declare COVID-19 outbreak a *** Spain,the virus started infecting the country slowly until rapid growth of infected people occurred in madrid,Barcelona and other major *** government in an attempt to stop the rapssid spread of the virus and ensure that health system will not reach its capacity,implement strict measures by putting the entire country in *** duration of these measures,depends on the evolution of the virus in *** this study,a Deep Neural Network approach using monte Carlo is proposed for generating a database to train networks for estimating the optimal parameters of a SIR epidemiology *** number of total infected people as of April 7 in Spain is considered as input to the Deep Neural *** adaptability of the model was evaluated using the latest data upon completion of this paper,i.e.,April *** date range for the peak of infected people(i.e.,active cases)based on the new information is estimated to be within 74 to 109 days after the first recorded case of COVID-19 in *** addition,a curve fitting measure based on the squared Euclidean distance indicates that according to the current data the peak might occur before the 86th ***,Deep Neural Networks have proven accurate and useful tools in handling big epidemiological data and for peak prediction estimates.

关键词： Coronavirus deep neural network machine learning monte Carlo simulation SIR model

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Vertebral fracture assessment:Current research status and application in patients with kyphoplasty

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World Journal of Orthopedics 2015年第9期6卷 680-687页

作者： Efstathios Drampalos Konstantinos Nikolopoulos Christos baltas Alexia Balanika Antonis Galanos Nikolaos Papaioannou Spyros Pneumaticos Laboratory for the Research of the musculoskeletal System (LRmS) Faculty of MedicineUniversity of Athens Center for Hip Surgery Wrightington Hospital C’ Orthopedic Department University of Athens"K.A.T" Hospital

Imaging of the spine is of paramount importance for the recognition of osteoporotic vertebral fractures(VFs), and standard radiography(SR) of the spine is the suggested diagnostic method but is not routinely used because of the cost and radiation exposure considerations. VF assessment(VFA) is an efficient, low radiation method for identifying VFs at the time of bone mineral density(BmD) measurement. Prediction models used to indicate the need for VFA may have little predictive power in subspecialty referral populations such as rheumatologic patients or patients who underwent kyphoplasty. Rheumatologic patients are frequently at increased risk for VFs, and VFA should be performed on an individual basis, also taking in account the guidelines for the general population. Kyphoplasty is a new minimal invasive procedure for the treatment of VFs and is being performed with increasing frequency. Following kyphoplasty, there may be a risk of new VFs in adjacent vertebrae. The assessment and follow-up of patients who underwent kyphoplasty requires repetitive X-ray imaging with the known limitations of SR. Thus, VFA may facilitate the evaluation of VFs in these patients because most of the kyphoplasty patients would fulfill the criteria. In a pilot study, we measured the BmD and performed VFA in 28 patients treated with kyphoplasty. Ratios of anterior to posterior(A/P) and middle to posterior(m/P) height were measured, and Genant's method was used to classify vertebrae accordingly. Intraobserver and interobserver reliability for A/P, m/P and the Genant's method were determined. Only 1 patient did not meet the criteria for VFA. Of the 364 available vertebrae, 295 could be analyzed. most missing data(concerning 69 vertebrae) occurred in the upper thoracic region. Three of the 69 non-eligible vertebrae were lumbar vertebrae with cement leakage from the kyphoplasty procedure. In our hands, VFA was highly reproducible, demonstrating very good agreement in terms of intraobserver and

关键词： Vertebral fracture assessment Current research Kyphoplasty Guideline

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希腊Hellas高血压患病率、知晓率、治疗和控制率:希腊Hellas综合医疗国家高血压研究

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心血管病学进展 2006年第5期27卷 678-678页

作者： Efstratopoulos AD Voyaki S m.baltas A A 李悦琳（摘译）曾朝荣（校）不详成都市第七人民医院

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