检索结果-南通市图书馆

Rating damage potential of ground motion records

在线全文

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2019年第2期18卷 233-254页

作者： bhargavi Podili Raghukanth S.T.G Department of Civil Engineering Indian Institute of Technology Madras

In this study, a total of 115,246 ground motions recorded during earthquakes of moment magnitudes ranging from m_w 5.0 to m_w 9.0 are analyzed statistically. A total of 21 ground motion parameters characterising the recorded acceleration time histories are used in the analysis. Classification of these parameters through statistical correlation is reported and a parameter called "distance from zero-amplitude axis," or d_(Z-A), is formulated in the principal component space. The ability for d_(Z-A) to rate the damage potentials of strong motion records is evaluated through correlation of d_(Z-A) with Japan meteorological Agency(JmA) instrumental seismic intensities. This parameter can be used to rate damage potential of any strong motion record irrespective of the magnitude and location of the earthquake. It can also be used in selecting ground motion records of appropriate damage potential in seismic design and probabilistic analysis.

关键词： damage potential principal component analysis ground motion parameters zero-amplitude axis

In vitro fertilization: Facts in medical sciences

在线全文

学校读者我要写书评

暂无评论

Asian pacific Journal of Reproduction 2018年第4期7卷 145-150页

作者： S.bhargavi Subhalaxmi Swain Abhisek mishra Arun Kumar Pradhan Centre for Biotechnology Siksha O Anusandhan(Deemed to be University)BhubaneswarIndia m/S Odisha NET Academy&Research Centre BhubaneswarOdishaIndia

In vitro fertilization (IVF) is one of the assisted reproductive technologies in the field of medical sciences. Fusion of collected egg from female and sperm from male done in a culture media under aseptic condition in laboratory is called as IVF. This technique is one of the gifts of science towards the human society and mainly those who are facing problem in reproduction due to having either male or female defective reproductive systems. In this present study, factors to consider during IVF, steps followed in this technology, need of IVF are discussed. Risk of multiple birth and phenotypic changes to the newborn due to IVF are also well reviewed. And different types of instruments used during this process are focused. Few ethical and legal issues arising during this IVF process are shown as well. We also emphasize that part of IVF.

关键词： In vitro fertilization Insemination Embryo transfer Blastocyst Infertility

Role of Positive Selection Pressure on the Evolution of H5N1 Hemagglutinin

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2009年第1期7卷 47-56页

作者： Venkata R.S.K. Duvvuri bhargavi Duvvuri Wilfred R. Cuff Gillian E. Wu Jianhong Wu Center for Disease modeling York Institute of Health Research York University Toronto Ontario M3J 1P3 Canada School of Kinesiology and Health Sciences York University Toronto Ontario M3J 1P3 Canada National microbiology Laboratory Public Health Agency of Canada Winnipeg Manitoba R3E 3R2 Canada Department of mathematics and Statistics York University Toronto Ontario M3J IP3 Canada

The surface glycoprotein hemagglutinin （HA） helps the influenza A virus to evade the host immune system by antigenic variation and is a major driving force for viral evolution. In this study, the selection pressure on HA of H5N1 influenza A virus was analyzed using bioinformatics algorithms. most of the identified positive selection （PS） sites were found to be within or adjacent to epitope sites. Some of the identified PS sites are consistent with previous experimental studies, providing further support to the biological significance of our findings. The highest frequency of PS sites was observed in recent strains isolated during 2005-2007. Phylogenetic analysis was also conducted on HA sequences from various hosts. Viral drift is almost similar in both avian and human species with a progressive trend over the years. Our study reports new mutations in functional regions of HA that might provide markers for vaccine design or can be used to predict isolates of pandemic potential.

关键词： positive selection H5N1 hemagglutinin epitope bioinformatics

Cryo-Em Structure of influenza Virus RNA Polymerase Complex at 4.3? Resolution

在线全文

学校读者我要写书评

暂无评论

Cryo-EM Structure of influenza Virus RNA Polymerase Complex ...

一种可能的制革体系:三元溶剂(水-乙醇-乙酸乙酯)在制革中的应用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者：刘迎芳 Shenghai Chang Dapeng Sun Huanhuan Liang Jia Wang Jun Li Lu Guo Xiangli Wang Chengcheng Guan bhargavi m.Boruah Lingmin Yuan Feng Feng mingrui Yang Lulan Wang Yao Wang Justyna Wojdyla Lanjuan Li Jiawei Wang meitian Wang Genhong Cheng Hong-Wei Wang 中国科学院生物物理研究所 Tsinghua University University of California 3Swiss Light Source Paul Scherrer Institute Zhejiang University

＜正＞The influenza virus genome is transcribed and replicated by the heterotrimeric RNAdependent RNA polymerase（RdRP）,which compriseses subunits PA,PB1 and *** extensively studied,the underlying mechanism of the RdRP complex is still unclear,largely owing to the lack of atomic resolution structural information on

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中国皮革 2019年第2期48卷 43-44,45-50,52页

作者： Solomon Fessehaye bhargavi Narayana Reddy Gari Rathinam Aravindhan Kalarical Janardhanan Sreeram Jonnalagadda Raghava Rao1 Balachandran Unni Nair 王玉增(译) 中央皮革研究所科学与工业研究中心化学实验室钦奈安达亚印度皮革技术局皮革行业发展研究所24692代码1000 四川大学

报道了一种尝试利用三元混合溶剂代替水(7～10 m^3/t)在制革中的应用,该混合溶剂具有比水更低的沸点(便于通过蒸发回收),对传统染料、合成鞣剂及加脂剂具有较大溶解度。该三元混合溶剂(水-乙醇-乙酸乙酯)对制革试剂具有较好的溶解分散能... 详细信息

报道了一种尝试利用三元混合溶剂代替水(7～10 m^3/t)在制革中的应用,该混合溶剂具有比水更低的沸点(便于通过蒸发回收),对传统染料、合成鞣剂及加脂剂具有较大溶解度。该三元混合溶剂(水-乙醇-乙酸乙酯)对制革试剂具有较好的溶解分散能力,合成鞣剂及染料在混合溶剂和水中的平均分散粒子大小是一样的,但是混合溶剂对染料及合成鞣剂粒子的分散更有利,即在混合溶剂中分散性更好。试验发现,与传统方法相比,鞣制后的中和过程在混合溶剂中使用中和合成鞣剂更容易获得性能优异的皮革。在水和混合溶剂中进行的染料吸附试验符合弗罗德利克吸附理论,说明染料的吸附是多分子层吸附。试验组的皮革的物理性能与对照组非常相似,说明该混合溶剂不会对胶原产生不利影响,并且对制革试剂具有较好的分散和固定作用。因此,该方法可以通过对制革生产工序中小的改变,提供有效的节水方案。

关键词：三元混合溶剂弗罗德利希吸附模型扩散

流感病毒RNA聚合酶复合体的4.3埃分辨率冷冻电镜结构

在线全文

学校读者我要写书评

暂无评论

科学新闻 2016年第1期 80-80页

作者： Shenghai Chang Dapeng Sun Huanhuan Liang Jia Wang Jun Li Lu Guo Xiangli Wang Chengcheng Guan bhargavi m.Boruah Lingmin Yuan Feng Feng mingrui Yang Lulan Wang Yao Wang Justyna Wojdyla 李兰娟 Jia-Wei Wang meitian Wang 程根宏王宏伟刘迎芳浙江大学医学院瑞士保罗谢尔研究所美国加州大学洛杉矶分校清华大学生命科学学院中国科学院生物物理研究所

文章简介揭示流感病毒RNA聚合酶复合体的三维结构是揭示其功能机制的重要基础。团队经过多年努力,成功获得了大量均一性好的该三维复合体的蛋白,通过使用最新的高分辨率单颗粒冷冻电镜三维重构技术,解析了含有A型流感病毒RNA聚合酶大部... 详细信息

文章简介揭示流感病毒RNA聚合酶复合体的三维结构是揭示其功能机制的重要基础。团队经过多年努力,成功获得了大量均一性好的该三维复合体的蛋白,通过使用最新的高分辨率单颗粒冷冻电镜三维重构技术,解析了含有A型流感病毒RNA聚合酶大部分成分的4.3埃分辨率的四聚体电镜结构。该复合体涵盖了流感病毒聚合酶催化活性的核心区域。四聚体的每个单体内部有一个空腔。从三维重构密度图中可以清晰识别出该空腔内PB1上的催化结构域以及结合的RNA复制起始链,推测是进

关键词：流感病毒聚合酶多聚酶转肽酶 RNA 分辨率鉴别率