检索结果-南通市图书馆

Endoscopic anti-reflux therapy for gastroesophageal reflux disease

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2021年第39期27卷 6601-6614页

作者： Enrique Rodríguez de Santiago Eduardo albéniz Fermin Estremera-Arevalo Carlos Teruel Sanchez-Vegazo Vicente Lorenzo-Zúñiga Department of Gastroenterology and Hepatology Hospital Universitario Ramón y CajalInstituto Ramón y Cajal de Investigación Sanitaria(IRYCIS)Madrid 28034Spain Endoscopy Unit Gastroenterology DepartmentHospital Universitario de Navarra.Gastrointestinal Endoscopy Research UnitNavarrabiomed Biomedical Research Center.PamplonaSpain Endoscopy Unit Gastroenterology DepartmentHospital Universitari i Politècnic La FeInstituto de Investigación Sanitaria La Fe(IIS La Fe)Valencia 46026Spain

Gastroesophageal reflux disease has an increasing incidence and prevalence worldwide.A significant proportion of patients have a suboptimal response to proton pump inhibitors or are unwilling to take lifelong medication due to concerns about long-term adverse *** anti-reflux therapies offer a minimally invasive option for patients unwilling to undergo surgical treatment or take lifelong *** best candidates are those with a good response to proton pump inhibitors and without a significant sliding hiatal *** incisionless fundoplication and nonablative radiofrequency are the techniques with the largest body of evidence and that have been tested in several randomized clinical ***-assisted ligation techniques,anti-reflux mucosectomy,antireflux mucosal ablation,and new plication devices have yielded promising results in recent noncontrolled ***,the role of endoscopic procedures remains controversial due to limited long-term and comparative data,and no consensus exists in current clinical *** review provides an updated summary focused on the patient selection,technical details,clinical success,and safety of current and future endoscopic anti-reflux techniques.

关键词： Treatment Gastroesophageal reflux Transoral incisionless fundoplication Anti-reflux mucosectomy Anti-reflux mucosal ablation Stretta

Liquid metal as energy transportation medium or coolant under harsh environment with temperature below zero centigrade

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers in Energy 2014年第1期8卷 49-61页

作者： Yunxia GA0 Lei WANG Haiyan LI Jing LIU Key Lab of Cryogenics and Beijing Key Lab of CryoBiomedicalEngineering Technical Institute of Physics and Chemistry ChineseAcademy of Sciences Beijing 100190 China Department of Biomedical Engineering School of Medicine TsinghuaUniversity Beijing 100084 China

The current highly integrated electronics and energy systems are raising a growing demand for more sophisticated thermal management in harsh environments such as in space or some other cryogenic environment. Recently, it was found that room temperature liquid metals （RTLm） such as gallium or its alloys could significantly reduce the electronics temperature compared with the conventional coolant, like water, oil or more organic fluid. However, most of the works were focused on RTLm which may subject to freeze under low temperature. So far, a systematic interpretation on the preparation and thermal properties of liquid metals under low temperature （here defined as lower than O^C） has not yet been available and related applications in cryogenic field have been scarce. In this paper, to promote the research along this important direction and to overcome the deficiency of RTLm, a comprehensive evaluation was proposed on the concept of liquid metal with a low melting point below zero centigrade, such as mercury, alkali metal and more additional alloy candidates. With many unique virtues, such liquid metal coolants are expected to open a new technical frontier for heat transfer enhancement, especially in low temperature engineering. Some innovative ways for making low melting temperature liquid metal were outlined to provide a clear theoretical guideline and perform further experiments to discover new materials. Further, a few promising applied situations where low melting temperature liquid metals could play irreplaceableroles were detailed. Finally, some main factors for optimization of low temperature coolant were summarized. Overall, with their evident merits to meet various critical requirements in modem advanced energy and power industries, liquid metals with a low melting temperature below zero centigrade are expected to be the next- generation high-performance heat transfer medium in thermal managements, especially in harsh environment in space.

关键词： liquid metal cryogenics low melting point,thermal management aircraft liquid cooling spaceexploration

Responses of CO_2 in surface water in subtropical West Pacific to El Nio event

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2001年第1期20卷 39-50页

作者： Xing Runan 1, ma Liming 2, Qiao Ran 2,Wang Zhanggui 21 .TrainingCenterofChinesemeteorologicalAdministration ,Beijing 10 0 0 81,China2 .NationalResearchCenterformarineEnvironmentalForecasts ,StateOceanicAdministration ,Beijing 10 0 0 81,China

In order to investigate the relationships between the change of T CO 2 , Δ P CO 2 and SST, current, upwelling and biological activities during El Nio event in the subtropical Pacific, the responses of T CO 2 and Δ P CO 2 in surface water in the subtropical Pacific during El Nio and La Nina have been simulated using a three dimension carbon cycle model with biota pump. The results of numerical simulations show that T CO 2 in sea water increases with reducing of SST during mature phase of El Nio in the subtropical West Pacific . At the same period ,the Kuroshio in this region was weakened ,the zonal currents were divergence , the upwelling carried the water with high concentrations of CO 2 to the sea surface , so both of T CO 2 and Δ P CO 2 in surface water were increased . But T CO 2 and Δ P CO 2 were decreased during La Nina period. These simulated results confirmed the observations in 1982/1983 , 1986/1987 , 1991/1995 and 1997/1998 El Nio events .

关键词： CO 2 El Nio the subtropical West Pacific

在线全文

学校读者我要写书评

暂无评论

五个氨基酸磷光性质的研究

生物化学与生物物理进展 1997年第1期24卷 60-63页

作者：黄如衡军事医学科学院毒物药物研究所北京100850

研究了 5个氨基酸的磷光特性、光谱、寿命和最小检测量 .以色氨酸 (Trp)的磷光最强 ,在λex/λem=2 90 /4 38nm ,最小检测量为 1ng ,酪氨酸 (Tyr)其次 ( 2 84 /390nm)为Trp的 1 /1 0 ,苯丙氨酸 (Phe)在 2 76/386nm ,脯氨酸 (Pro)在 30 8... 详细信息

研究了 5个氨基酸的磷光特性、光谱、寿命和最小检测量 .以色氨酸 (Trp)的磷光最强 ,在λex/λem=2 90 /4 38nm ,最小检测量为 1ng ,酪氨酸 (Tyr)其次 ( 2 84 /390nm)为Trp的 1 /1 0 ,苯丙氨酸 (Phe)在 2 76/386nm ,脯氨酸 (Pro)在 30 8/4 54nm ,组氨酸 (His)在 32 0 /4 66nm ,其磷光只有Trp的 1 % .Phe与Trp磷光寿命最长 ,在 7s左右 ;His最短 ,只有 0 4 9s;Tyr 2 8s,Pro 1 34s.另外研究氨基酸在甲醇 ,乙醇 ,丙醇 ,丁醇中及pH对氨基酸磷光性质的影响 .还计算了Stokes位移能量及激化态 pK a

关键词：氨基酸膦光性质磷光

在线全文

学校读者我要写书评

暂无评论

细胞质膜微囊与信号转导

生物化学与生物物理进展 1997年第3期24卷 194-198页

作者：黄芬中国科学院生物物理研究所

细胞质膜微囊 (caveolae)为 50～ 1 0 0nm的小囊泡 ,它们以内陷形式连接在细胞质膜上 ,并广泛存在于各种类型的细胞 .早在 4 0多年前用透射电镜曾观察到此微囊结构 .细胞质膜微囊的功能为通过毛细管内皮细胞转运小分子及大分子以及具有... 详细信息

细胞质膜微囊 (caveolae)为 50～ 1 0 0nm的小囊泡 ,它们以内陷形式连接在细胞质膜上 ,并广泛存在于各种类型的细胞 .早在 4 0多年前用透射电镜曾观察到此微囊结构 .细胞质膜微囊的功能为通过毛细管内皮细胞转运小分子及大分子以及具有“液饮”作用 .最近实验表明。

关键词：细胞学细胞质膜微囊微囊蛋白信号转导

A GPA diagnostic system foraeroengine applications

在线全文

学校读者我要写书评

暂无评论

航空动力学报 2007年第6期22卷 898-908页

作者： Yi-Guang Li(School of Engineering,Cranfield University,Cranfield,Bedford mK43 0AL,England) School of Engineering Cranfield University England

In this research,a GPA(Gas Path Analysis) diagnostic system enhanced with GPA Index is described for gas path sensor and component fault diagnosis.A method of measurement correction is used in order that the measurement data obtained at un-standard ambient and operating conditions can be used for diagnostic *** developed diagnostic system has been implemented into a Cranfield University gas turbine performance and diagnostic analysis software PYTHIA for gas turbine performance degradation *** developed method and software have been applied to a model aero gas turbine engine to test the effectiveness of the *** analysis shows that the developed diagnostic system can diagnose degraded sensor and components effectively using performance deviation measured at un-standard ambient and operational ***,the idea of the diagnostic approach can be applied to different gas turbine engines.

关键词：航空发动机燃气涡轮诊断系统气体分解

Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2454-2463页

作者： Victoria Jiménez Carretero IrisÁlvarez-merz Jorge Hernández-Campano Sergei A.Kirov Jesús m.Hernández-Guijo Department of Pharmacology and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute for Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of Neurobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neuroscience and Regenerative medicine&Department of Neurosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is ***,the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely *** release of amino acids by necrotic cells in the ischemic core may contribute to the expansion of the *** findings indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia became irreversible when exposed to a mixture of just four non-excitatory amino acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino acids induce swelling in the somas of neurons and astrocytes during hypoxia,along with permanent dendritic damage mediated by N-methyl-D-aspartate *** N-methyl-D-aspartate receptors prevented neuronal damage in the presence of these amino acids during *** is likely that astroglial swelling caused by the accumulation of these amino acids via the alanine-serine-cysteine transporter 2 exchanger and system N transporters activates volume-regulated anion channels,leading to the release of excitotoxins and subsequent neuronal damage through N-methyl-D-aspartate receptor ***,previously unrecognized mechanisms involving non-excitatory amino acids may contribute to the progression and expansion of brain injury in neurological emergencies such as stroke and traumatic brain *** these pathways co uld highlight new therapeutic targets to mitigate brain injury.

关键词： cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids stroke synaptic transmission

A Study of the Lithic Assemblage from Zhoukoudian Locality 15

在线全文

学校读者我要写书评

暂无评论

人类学学报 2002年第S1期21卷 31-52页

作者： GAOXing (Institute of Vertebrate Paleontologyand Paleoanthropology ,Chinese Academy of Sciences P .O .Box 6 43,Beijing 10 0 0 4 4,P .R .China )

Numerical Study of Phase Transition in Thermoviscoelasticity

在线全文

学校读者我要写书评

暂无评论

Communications in Nonlinear Science and Numerical Simulation 1997年第4期2卷 207-212页

作者： The paper was received on Nov. 10 ,1997. Shaoqiang TANG (Dept. of mech. &Engin. Sci.,Peking University,Beijing 1 0 0 871 ,P.R. China) E- mail:tangsq@*** Department of mechanics and Engineering Science Peking University Beijing 100871 China

We study the spatially periodic problem of thermoviscoelasticity with nonmonotone structure *** pseudo- spectral method,we demonstrate numerically phase transitions for certain symmetric initial data. Without symmetry... 详细信息

关键词： phase transition. thermoviscoelasticity. mixed- type problem.