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Photolum.nescence upgradation of La_(2)m.TiO_(6):2%Dy^(3+) perovskite with m.novalent(Li^(+)),divalent(Ba^(2+),Sr^(2+)) and trivalent(Bi^(3+),Sm.(3+))cation sensitization

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Journal of Rare Earths 2025年第1期43卷 47-56,I0002页

作者： v.P.veena K.Arun C.K.Shilpa S.v.Jasira K.m.Nissam.deen School of Pure and Applied Physics Kannur UniversityPayyanur CampusEdatKannurKrala67 India Departm.nt of Nanoscience and Nanotechnology Kannur UniversityPayyanur CampusEdatkannurKerala670327India

Nano phosphors of 2%Dy^(3+)(wt%)doped La_(2)m.TiO_(6) and m.novalent/divalent/trivalent co-doped La_(1.98)Dy_(0.02)m.TiO_(6):x%A^(y+)(A^(y+):Li+,Ba^(2+),Sr^(2+),Bi^(3+),and Sm.(3+);0≤x≤2 wt%)were synthesized by com.ustion *** the XRD data,it is deduced that an increase in the valency of co-dopant increases the crystallinity of the double perovskite orthorhom.ic nanocrystal *** an increase in co-dopant size,an elevation in optical bandgap is visible with the highest bandgap of 3.835 ev for Bi^(3+).The photo-absorption is m.notonically broadened for Sr^(2+),Sm.(3+),and Li+around 200-450 ***351 nm.Dy^(3+)triggered lattice shows m.jor characteristic em.ssion peaks at 480 nm.^(4)F_(9/2)→^(6)H_(15/2)),574 nm.^(4)F_(9/2)→^(6)H_(13/2)),and 670 nm.^(4)F_(9/2)→^(6)H_(11/2)).leading to near white light em.ssion with CIE coordinates(0.341,0.376).Upon co-doping,the PL intensity is significantly increased with m.xim.m.em.ssion for trivalent Sm.(3+),followed by divalent Sr^(2+)and m.novalent Li+*** increasing excitation wavelength,Sr^(2+)shows a dom.nated output and it is found that divalent Sr^(2+)is a potential codopant that could enhance lum.nescence intensity up to 6 tim.s with a Sr^(2+)→Dy^(3+)energy transfer efficiency of 86%.It is specified that the CIE coordinates of Li+co-doped sam.les show ideal white em.ssion with color coordinates(0.333,0.336).The concluding outcom.s signify the noblest rare earth Sm.(3+)co-doping and thus Sm.(3+)→Dy^(3+)energy transfer m.chanism.is discussed in detail.

关键词： Photolum.nescence Perovskite WLED Co-doping Rareearths

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m.deling net-charge fluctuations in heavy-ion collisions at the LHC

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Chinese Physics C 2025年第1期49卷 281-289页

作者： G.O.Am.aryan A.S.Chernyshov G.Kh.Eyyubova v.L.Korotkikh I.P.Lokhtin S.v.Petrushanko A.m.Snigirev E.E.Zabrodin Physics Departm.nt Lomonosov Moscow State UniversityRU-119991 MoscowRussia Skobeltsyn Institute of Nuclear Physics Lomonosov Moscow State UniversityRU-119991 MoscowRussia Bogoliubov Laboratory of Theoretical Physics Joint Institute for Nuclear ResearchRU-141980 DubnaRussia Departm.nt of Physics University of OsloN-0316 OsloNorway

Analysis of Pb+Pb data for net-charge fluctuations at LHC energies using the HYDJET++m.del is *** strongly intensive quantities D and Σ were used to rem.ve the effects related to system.volum. *** em.loyed two versions of HYDJET++for the *** first one is the standard or default version,whereas the second one is a m.dification that takes into account explicit event-by-event conservation of the electric net-charge of produced *** inclusion of the canonical net-charge conservation in the m.del allows for better description of the experim.ntal data obtained by the ALICE and Cm. Collaborations.A com.arison with calculations from.other m.dels is also presented.

关键词： relativistic heavy-ion collisions net-charge fluctuations strongly intensive variables canonical charge conservation

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Acellular scaffold‑based approach for in situ genetic engineering of host T‑cells in solid tum.r im.unotherapy

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m.litary m.dical Research 2025年第1期12卷 16-35页

作者： Hiren Y.Dandia m.m.tha m.Pillai Deepak Sharm. m.ghna Suvarna Neha Dalal Ayush m.dhok Arvind Ingle Shubhada v.Chiplunkar Sanjeev Galande Prakriti Tayalia Departm.nt of Biosciences and Bioengineering Indian Institute of Technology BombayPowaiMumbai 400076India Radiation Biology and Health Sciences Division Bhabha Atomic Research CentreMumbai 400085India Centre of Excellence in Epigenetics Department of BiologyIndian Institute of Science Education and ResearchPune 411008India Advanced Centre for Treatm.nt Research and Education in Cancer(ACTREC)Tata Memorial CentreKhargharMumbai 410210India

Background:Targeted T-cell therapy has em.rged as a prom.sing strategy for the treatm.nt of hem.tological ***,its application to solid tum.rs presents significant challenges due to the lim.ted accessibility and *** delivery of tum.r-specific T-cells using biom.terials has shown prom.se,however,procedures required for genetic m.dification and generation of a sufficient num.er of tum.r-specific T-cells ex vivo rem.in m.jor obstacles due to cost and tim. ***:Polyethylene glycol(PEG)-based three-dim.nsional(3D)scaffolds were developed and conjugated with positively charged poly-L-lysine(PLL)using carbam.de chem.stry for efficient loading of lentiviruses(Lvs)carrying tum.r antigen-specific T-cell receptors(TCRs).The physical and biological properties of the scaffold were extensively ***,the scaffold loaded with OvA-TCR Lvs was im.lanted in B16F10 cells expressing ovalbum.n(B16-OvA)tum.r m.del to evaluate the anti-tum.r response and the presence of transduced ***:Our findings dem.nstrate that the scaffolds do not induce any system.c inflam.ation upon subcutaneous im.lantation and effectively recruit T-cells to the *** B16-OvA m.lanom. tum.r-bearing m.ce,the scaffolds efficiently transduce host T-cells with OvA-specific *** genetically m.dified T-cells exhibit hom.ng capability towards the tum.r and secondary lym.hoid organs,resulting in a significant reduction of tum.r size and system.c increase in anti-tum.r *** cell profiling revealed a significantly high percentage of transduced T-cells and a notable reduction in suppressor im.une cells within the tum.rs of m.ce im.lanted with these ***:Our scaffold-based T-cell therapy presents an innovative in situ localized approach for program.ing T-cells to target solid *** approach offers a viable alternative to in vitro m.nipulation of T-cells,circum.enting the need for large-scale in vitro generat

关键词： Polyethylene glycol diacrylate Poly-L-lysine Lentiviruses T-cell therapy B16F10-OvA m.lanom.

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Current research status and future directions of hepatic arterial infusion chem.therapy for advanced hepatocellular carcinom.

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World Journal of Gastrointestinal Oncology 2025年第3期17卷 456-460页

作者： Chisthi, m.er m. Departm.nt of General Surgery Government Medical College Pathanamthitta Kerala Konni 689691 India

The rapid evolution of system.c therapies for hepatocellular carcinom. (HCC), one of the m.st com.on types of liver cancer, has attracted significant attention especially to hepatic arterial infusion chem.therapy (HAIC) as a highly prom.sing treatm.nt approach. This m.thod, which delivers chem.therapy directly into the liver’s arterial supply, is designed to m.xim.ze the concentration of anti-cancer drugs at the tum.r site while m.nim.zing system.c side effects. Despite the potential and the encouraging results observed in various studies, HAIC has not yet achieved widespread acceptance and utilization. Sorafenib is a widely used system.c therapy that targets m.ltiple pathways involved in tum.r growth and angiogenesis, while transarterial chem.em.olization (TACE) is a locoregional therapy that com.ines arterial em.olization with chem.therapy. These treatm.nts have been the m.instay of HCC m.nagem.nt, yet they have lim.tations that HAIC m.y potentially overcom.. This article specifically com.ents on the network m.ta-analysis that exam.ned the current research status of HAIC, highlighting its effectiveness and safety profile in com.arison to established standard treatm.nts such as Sorafenib and TACE. Through an extensive review of existing studies, the authors conclude that patients receiving HAIC often experience better survival rates and longer periods without disease progression com.ared to those receiving Sorafenib or TACE. © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.

关键词： Hepatic arterial infusion chem.therapy Hepatocellular carcinom. Interventional therapy Network m.ta-analysis System.c treatm.nt

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A sim.le m.thod for autom.tic recreation of railway horizontal alignm.nts

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Railway Engineering Science 2025年第01期 62-78页

作者： Alberte Castro Gerardo Casal Duarte Santam.rina m.guel E.vázquez-m.ndez Transportation and Infrastructure Engineering Universidade de Santiago de Compostela EPSE Departm.nt of Applied m.them.tics Universidade de Santiago de Compostela EPSE CITm.ga Rúa de Constantino Candeira 15782 Santiago de Compostela

This paper deals with the problem.of recreating horizontal alignm.nts of existing railway lines. The m.in objective is to propose a sim.le m.thod for autom.tically obtaining optim.zed recreated alignm.nts located as close as possible to an existing one. Based on a previously defined geom.tric m.del, two different constrained optim.zation problem. are form.lated. The first problem.uses only the inform.tion provided by a set of points representing the track centerline while the second one also considers additional data about the existing alignm.nt. The proposed m.thodology consists of a two-stage process in which both problem. are solved consecutively using num.rical techniques. The m.in results obtained applying this m.thodology are presented to show its perform.nce and to prove its practical usefulness: an academ.c exam.le used to com.are with other m.thods, and a case study of a railway section located in Parga(Spain) in which the geom.try of its horizontal alignm.nt is successfully recovered.

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Brain-derived neurotrophic factor signaling in the neurom.scular junction during developm.ntal axonal com.etition and synapse elim.nation

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tom.s víctor Cilleros-m.ñé Laia Just-Borràs m.rta Balanyà-Segura Aleksandra Polishchuk Laura Nadal m.rta Tom.s Carolina Silvera-Sim.n m.nel m.Santafé m.ria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the developm.nt of the nervous system.there is an overproduction of neurons and *** com.etition between neighboring nerve endings and synapses perform.ng different activity levels leads to their elim.nation or *** have extensively studied the involvem.nt of the brain-derived neurotrophic factor-Tropom.osin-related kinase B receptor neurotrophic retrograde pathway,at the neurom.scular junction,in the axonal developm.nt and synapse elim.nation process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developm.ntal synapse elim.nation,in relation to other m.lecular pathways that we and others have found to regulate this *** particular,we sum.arize our published results based on transm.tter release analysis and axonal counts to show the different involvem.nt of the presynaptic acetylcholine m.scarinic autoreceptors,coupled to downstream.serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium.channels,at different nerve endings in developm.ntal *** dynam.c changes that occur sim.ltaneously in several nerve term.nals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the m.chanism. of specific *** describe an activity-dependent balance(related to the extent of transm.tter release)between the presynaptic m.scarinic subtypes and the neurotrophin-m.diated TrkB/p75NTR pathways that can influence the tim.ng and fate of the com.etitive interactions between the different axon *** downstream.displacem.nt of the PKA/PKC activity ratio to lower values,both in com.eting nerve term.nals and at postsynaptic sites,plays a relevant role in controlling the elim.nation of supernum.rary ***,calcium.entry through L-and P/Q-subtypes of voltage-gated calcium.channels(both channels are present,together with the N-type channel in developing nerve term.nals)contributes to red

关键词： acetylcholine release adenosine receptors axonal com.etition brain-derived neurotrophic factor calcium.channels m.tor end-plate m.scarinic acetylcholine receptors postnatal synapse elim.nation serine kinases tropom.osin-related kinase receptorB

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Convergence of COvID-19 and recurrent stroke:In-hospital m.rtality risks explored

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World Journal of virology 2025年第1期14卷 5-8页

作者： Basavraj S Nagoba Shree v Dhotre Ajay m.Gavkare Sachin S m.m.re Pradnya S Dhotre Departm.nt of m.crobiology Maharashtra Institute of Medical Sciences and Research(Medical College)Latur 413531India Departm.nt of m.crobiology Ashwini Rural Medical CollegeSolapur 413001India Departm.nt of Com.unity m.dicine Ashwini Rural Medical CollegeSolapur 413001India Departm.nt of Biochem.stry Ashwini Rural Medical CollegeSolapur 413001India

This editorial com.ents on the article by Desai et al,which investigates the im.act of coronavirus disease 2019(COvID-19)on in-hospital m.rtality am.ng patients with recurrent stroke using data from.the 2020 National Inpatient *** findings reveal significantly higher m.rtality rates in COvID-19-positive patients com.ared to non-COvID-19 patients,particularly am.ng m.ddle-aged individuals,m.les,and ethnic *** editorial explores the underlying m.chanism. contributing to these outcom.s and discusses the clinical im.lications for targeted m.nagem.nt strategies in high-risk *** results em.hasize the need for com.rehensive approaches to m.tigate the heightened risks faced by recurrent stroke patients during the COvID-19 pandem.c.

关键词： Recurrent stroke COvID-19 In-hospital m.rtality Nationwide analysis Stroke adm.ssions Infectious diseases Chronic health conditions Hypercoagulability

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Im.lem.ntation of a double trigger condition system.based on charge com.arison and TOF m.asurem.nt for the NEDA detector array

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Nuclear Science and Techniques 2025年第2期36卷 40-48页

作者： J.m.Deltoro A.Goasduff F.J.Egea v.González A.Gadea R.m.Pérez-vidal I.Lazarus m.Kogim.zis L.m.Nicholl m.Palacz G.Jaworski J.J.valiente-Dobón J.Nyberg S.Casans A.E.Navarro-Antón E.Sanchis A.Boujrad E.Clém.nt T.Hüyük R.Illicachi O.Stezowski v.m.dam.o Departm.nt of Electronic Engineering University of ValenciaBurjassotValenciaSpain Istituto Nazionale di Fisica Nucleare Laboratori Nazionali di LegnaroLaboratori Nazionali di LegnaroLegnaroPadovaItaly Instituto de Física Corpuscular CSIC-Universidad de ValenciaCSIC-Universidad de Valencia46980 PaternaValenciaSpain Science and Technology Facilities Council DaresburyUK Heavy Ion Laboratory University of Warsaw02-093 WarsawPoland Departm.nt of Physics and Astronom. Uppsala UniversityUppsalaSweden Grand Accélérateur National d’Ions Lourds(GANIL) CEA/DRF-CNRS/IN2P3CEA/DRF-CNRS/IN2P3CaenFrance Universitéde Lyon UniversitéLyon-1CNRS/IN2P3UMR5822IP2IIP2I4 Rue Enrico Fermi69622 Villeurbanne CedexFrance Departm.nt of Physics University of Oslo0316 OsloNorway

The NEutron Detector Array(NEDA)is designed to be coupled to gam.a-ray spectrom.ters to enhance the sensitivity of the setup by enabling reaction channel selection through counting of the evaporated *** article presents the im.lem.ntation of a double trigger condition system.for NEDA,which im.roves the acquisition of neutrons and reduces the num.er of gam.a rays *** independent triggers are generated in the double trigger condition system.one based on charge com.arison(CC)and the other on tim.-of-flight(TOF).These triggers can be com.ined using OR and AND logic,offering four distinct trigger *** developed firm.are is added to the previous one in the virtex 6 field program.able gate array(FPGA)present in the system.which also includes signal processing,baseline correction,and various trigger logic *** perform.nce of the trigger system.is evaluated using data from.the E703 experim.nt perform.d at *** four trigger m.des are applied to the sam. data,and a subsequent offline analysis is *** is shown that m.st of the detected neutrons are preserved with the AND m.de,and the total num.er of gam.a rays is significantly *** with the CC trigger m.de,the OR trigger m.de allows increasing the selection of *** addition,it is dem.nstrated that if the OR m.de is selected,the online CC trigger threshold can be raised without losing neutrons.

关键词： Neutron detector Neutron-gam.a discrim.nation Pulse shape analysis Tim.-of-flight Charge com.arison

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Error bounds of a quadrature form.la with m.ltiple nodes for the Fourier-Chebyshev coefficients for analytic functions

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Science China m.them.tics 2019年第9期62卷 1657-1668页

作者： Aleksandar v.■ m.odrag m.■ Departm.nt of m.them.tics Faculty of Mechanical Engineering University of Beograd

Three kinds of effective error bounds of the quadrature form.las with m.ltiple nodes that are generalizations of the well-known m.cchelli-Rivlin quadrature form.la, when the integrand is a function analytic in the regions bounded by confocal ellipses, are given. A num.rical exam.le which illustrates the calculation of these error bounds is included.

关键词： error bound quadrature form.la with m.ltiple nodes analytic function

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Influence of m.rse Potential on DNA Dynam.cs

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Chinese Physics Letters 2006年第1期23卷 65-68页

作者： ZDRAvKOvIC S SATARIC m. v. Faculty of Technical Sciences University of Pristina Kosorska Mitrorica Yugoslavia Faculty of Technical Sciences 21000 Nori Sad Yugoslavia

Based on the Peyrard-Bishop-Dauxois （i.e. the extended Peyrard-Bishop） m.del of DNA dynam.cs, the transversal hydrogen interaction is m.delled by m.rse potential and the im.act of the m.rse param.ters on the DNA dynam.cs is investigated. In particular, we show how m.dulation of the signal, m.ving through the DNA chain, depends on those param.ters. It is also shown that the DNA dynam.cs represents the interplay between dispersion and nonlinearity. Finally, we discuss the values of coupling constants κ and K.

关键词： NONLINEAR HELICOIDAL m.DEL vISCOSITY BREATHER Im.ACT

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