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Im.unosuppressive Trea.m.nt of Connective Tissue Disea.e a.d Occurrence of Tuberculosis

Open Journa. of Rheum.tology a.d a.toim.une Disea.es 2020年第2期10卷 57-63页

作者： m. Dieng B. Djiba.B. S. Ka.e B. C. Fa.l m. a. ndour m. Sow N. Dia.ne a. C. Nda. a. Fa.e S. Ndongo a. Pouye Service de m.decine Interne hôpital Aristide Le Dantec Dakar-étoile Sénégal Service de m.decine interne hôpital Dalal Jam Dakar Sénégal

Introduction: The occurrence of tuberculosis (TB) during the follow-up of Connective tissue disea.es (CTD) is a.pa.ticula. situa.ion often posing rea. dia.nostic problem.. This is a. a.socia.ion described in the litera.ure. Pa.ients a.d m.thods: We conducted a.retrospective a.d descriptive study a. the interna. m.dicine depa.tm.nt of a.istide Le Da.tec Hospita.. The purpose of this study wa. to determ.ne the trea.m.nt tha. pa.ients followed for CTD a.d suffering from.TB took before the occurrence of this one. Results: During a.study period of 11 yea.s a.d 6 m.nths, 21 ca.es of TB were dia.nosed in 602 ca.es of CTD (0.03%). The predom.na.ce wa. fem.le with a.sex ra.io (H/F) of 0.6. The m.dia. a.e wa. 42 yea.s old. The m.jority of ca.es origina.ed from.the Da.a. region (13 pa.ients or 61.9%) a.d 85.7% ha. previous follow-up exclusively in m.dern m.dicine a.d 21 ca.es (95%) received the CTD’s trea.m.nt. This consisted of prednisone (90.5%) com.ined with m.thotrexa.e (52.4%), a.a.hioprine (23.8%) or cyclophospha.0}de (19.4%). The respective m.dia.s doses of these drugs were 12.5 m. per da. for prednisone, 13.5 m. per week for m.thotrexa.e a.d 100 m. per da. for a.a.hioprine. The m.dia. dura.ion of pa.ient follow-up wa. 36 m.nths. The cum.la.ive dose of prednisone during this period wa. 23.6 g a.d tha. of m.thotrexa.e 2.25 g. CTD were dom.na.ed by rheum.toid a.thritis (Ra. (57.1%), a.d system.c lupus (19%). Isola.ed ca.es of system.c scleroderm., prim.ry Sjôgren, SHa.P syndrom. m.xed connective tissue disea.e, a.d m.ltiple a.toim.une syndrom.were noted. TB wa. loca.ized in 95% of ca.es, rea.ily bila.era. a.d poorly dissem.na.ed. The respective m.dia.s dia.nostic dela.s for system.c disea.e a.d TB were 21 m.nths a.d 5 m.nths. Tuberculin intra.erm.l rea.tion wa. perform.d in 16 ca.es a.d wa. positive in 9 ca.es, sputum.ba.illi wa. perform.d in 19 ca.es a.d wa. positive in 15 ca.es. Conclusion: The a.socia.ion of TB a.d CTD wa. cha.a.terized by its ra.ity, its poorly di

关键词： Tuberculosis Connective Tissue Disea.e Corticosteroid Im.unosuppressive Thera.y

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Effectivity of Throm.oprophylxie in Da.a.’s m.dica. a.ea.

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Open Journa. of Interna. m.dicine 2020年第1期10卷 35-43页

作者： B. Djiba.m. Dieng C. m. a. Ha.im.m. Sow B. S. Ka.e m. a. ndour B. C. Fa.l N. Dia.ne a. C. Nda. a. Fa.e S. Ndongo a. Pouye Depa.tm.nt of Interna. m.dicine Aristide Le Dantec Hospital Dakar-Étoile Senegal Depa.tm.nt of Interna. m.dicine Dalal Jam Hospital Dakar Senegal

Introduction: Venous throm.oem.olic disea.e (VTE) is a.rea. public hea.th problem.worldwide. The pra.tice guide produced periodica.ly by the a.0}rica. College of Chest Physicia.s (a.CP) ha. becom. the interna.iona. sta.da.d. However, throm.oprophyla.is rem.ins underused. m.thodology: We ca.ried out a.descriptive cross-sectiona. study. The goa.s of tha. study were to eva.ua.e the effectiveness of the pra.tice of throm.oprophyla.is in the va.ious m.dica. services of the Da.a. Public Hospita.s. Our investiga.ion wa. conducted for two weeks in Septem.er 2017. Results: 160 pa.ients were included (81 m.n a.d 79 wom.n) in our series, with m.le predom.na.ce: sex ra.io of 1.02. The a.era.e a.e wa. 48. Infectious pa.hologies were the predom.na.t clinica. pictures (35% of ca.es). The throm.oem.olic risk fa.tors (RF) m.inly found were represented by prolonged bed rest, followed by ca.diova.cula. (RF): a.e grea.er tha. 60 yea.s (31.2%), hypertension (8.8%), obesity (4.4%) a.d dia.etes (3.8%). The throm.oem.olic RF of pa.ients hospita.ized in these m.dica. services ha. been eva.ua.ed em.irica.ly. We noted a.la.k of use of the VTE risk a.sessm.nt scores. 40.9% (n = 56) of pa.ients received overa.l VTE prophyla.is, a.ra.e corresponding to a.m.st ha.f of those a. risk (51.4%). This result reflects a. under-use of throm.oprophyla.is in the Da.a. m.dica. environm.nt a.d a.low level of a.herence by pra.ticia.s to the guidelines on VTE prophyla.is. Conclusion: It is therefore recom.ended to develop a.na.iona. stra.egy to a.sess pa.ients a. risk for VTE, a. well a. m.a.ures to educa.e a.d inform.doctors a.out the a.propria.e form. of throm.oprophyla.is.

关键词： Throm.oprophyla.is a.ticoa.ula.t Throm.oem.olic Disea.e

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Long-Term.Ora. Corticosteroid-Thera.y: Description of the Pra.tice of a.juva.t m.a.ures by Da.a. m.dica. Specia.ists

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Open Journa. of Rheum.tology a.d a.toim.une Disea.es 2020年第2期10卷 70-78页

作者： m. Dieng B. Djiba.m. Sow B. S. Ka.e J. T. a.oua.dogbo m. Ba.m. a. ndour B. C. Fa.l m. Nia.se N. Dia.ne a. C. Nda. a. Fa.e S. Ndongo a. Pouye Depa.tm.nt of Interna. m.dicine Aristide Le Dantec Hospital Dakar-Etoile Senegal Depa.tm.nt of Interna. m.dicine Dalal Jam Hospital Dakar Senegal Depa.tm.nt of Rheum.tology Aristide Le Dantec Hospital Dakar-Etoile Senegal

Introduction: The extended a.m.nistra.ion of corticoids by ora. wa. for a.length of m.re tha. 3 m.nths defines the long-term.corticosteroid-thera.y. This one, used in num.rous indica.ions, displa.s m.st often a. the risk of undesira.le effects linked som.tim.s to the ha.its of prescription of the doctors. Pa.ients a.d m.thods: In order to study the prescription m.da.ities of this trea.m.nt, we conducted a.cross-sectiona., m.lticentric a.d descriptive study from.June 1st, 2017 to a.gust 1st, 2017, over a.period of 2 m.nths. It involved a.questionna.re given to m.dica. specia.ists of a.l m.dica. specia.ties a.d pra.ticing in the University Hospita. of Da.a.. Results: 170 doctors were interviewed. Derm.tologists a.d internists were m.stly found 19.4% a.d 18.8% or 33% a.d 34% doctors. System.c a.toim.une disea.es a.one a.counted for 48% of prescription rea.ons. Prednisone wa. prescribed in 88% of ca.es. The im.unosuppressive dose of 1 m./kg wa. m.st often prescribed. Pra.titioners very heterogeneously prescribe m.st a.juva.t m.a.ures to prolonged system.c corticosteroid thera.y. Thus, the recom.enda.ion of a.low-sodium.diet (38% of physicia.s), a.d the system.tic prescriptions of proton pum. inhibitors (44.7% of physicia.s) a.d vita.0}n-ca.cium.supplem.nta.ion were frequently perform.d by physicia.s (34% of physicia.s). While the low ca.bohydra.e diet wa. a.voca.ed by less tha. a.qua.ter of doctors a.d the prevention of pneum.cystosis a.d osteoporosis were ra.e (respectively 61% a.d 52% of prescribers did not). Conclusion: The globa. a.a.ysis of the ha.its of our m.dica. specia.ists concerning the use of long-term.glucocorticoids reflected a.diversity of indica.ions, heterogeneity of pra.tices, with certa.n ha.its not in a.corda.ce with the usua. recom.enda.ions.

关键词： Corticosteroid Long-Term Ora. Corticosteroid System.c Disea.e a.juva.t m.a.ures

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System.c Disea.es in Da.a. (Senega.): Spectrum. Epidem.ologica. a.pect a.d Dia.nostic Tim.-Lim.t

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Open Journa. of Interna. m.dicine 2018年第3期8卷 196-206页

作者： B. S. Ka.e m. Nia.se a. a. Ndia.e a. C. Nda. B. Djiba.N. D. Dia.k B. C. Fa.l m. a. ndour m. Dieng D. Dia.N. Dia.ne a. Fa.e a. Leye S. B. Gning S. Ndongo a. Pouye Depa.tm.nt of Interna. m.dicine Le Dantec Hospital/Cheikh Anta DIOP University Dakar Senegal Depa.tm.nt of Rheum.tology Le Dantec Hospital/Cheikh Anta DIOP University Dakar Senegal Epidem.ology Unit/University of Ba.0}ey Bambey Senegal Depa.tm.nt of Interna. m.dicine Pikine Hospital/Cheikh Anta DIOP University Dakar Senegal Depa.tm.nt of Interna. m.dicine Grand Yoff Hospital/Cheikh Anta DIOP University Dakar Senegal Depa.tm.nt of Interna. m.dicine Principal Hospital Dakar Senegal

Introduction: System.c disea.es ha.e been the subject of few studies in the a.rica. litera.ure a.d ha.e proba.ly been under-estim.ted. The objective of our study wa. to specify their spectrum. their epidem.ologica. a.pects a.d dia.nostic dela. in Interna. m.dicine Depa.tm.nts of Da.a. (Senega.). m.teria. a.d m.thod: It wa. a.m.lticentric retrospective a.d descriptive study rega.ding a.l system.c disea.es during 119 m.nths from.1st Ja.ua.y 2005 to 30 Novem.er 2014 in 5 hospita. centers down Da.a.. System.c disea.es were reta.ned a.cording to their interna.iona. consensus criteria. Results: During the studying period, 726 pa.ients were included with 632 wom.n a.d 94 m.n (sex ra.io of 0.14). The a.era.e a.e wa. 43.76 yea.s. Infla.0}a.ory rheum.toid fa.0}ly history wa. noted in 10.06% of ca.es. Rheum.toid a.thritis (Ra. wa. the predom.na.t a.fection, recorded on 564 pa.ients, isola.ed or a.socia.ed with other system.c disea.es. It wa. followed in a.decrea.ing order, in the system.c a.to-im.une disea.es sub-groupe, by system.c lupus (56 ca.es), Sj?gren’s syndrom. (32 ca.es), System.c Sclerosis (26 ca.es), Idiopa.hic infla.0}a.ory m.opa.hies (21 ca.es), Undifferentia.ed connective tissue disea.es (20 ca.es), a.ti Phospholipid’s syndrom. (6 ca.es) a.d m.xed connective tissue disea.e (6 ca.es). a.dia.nosis of system.c va.culitis wa. recorded in 19 pa.ients. The other system.c a.fections were represented by system.c sa.coidosis (8 ca.es), a.ult-onset Still’s disea.e (03 ca.es), a.0}loidosis (02 ca.es) a.d 02 ca.es of system.c syndrom. a.socia.ed to im.unodeficiency. The m.a. dia.nostic dela. dura.ion before the dia.nostic wa. 3.46 yea.s. Conclusion: System.c disea.es in interna. m.dicine a.e cha.a.terized by their diversity, the clea. predom.na.ce of Ra. a.d significa.t dia.nostic dela..

关键词： Connective Tissue Disea.e Rheum.toid a.thritis System.c Va.culitis Sa.coidosis a.ult-Onset Still’s Disea.e a.rica South of the Sa.a.a

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Survey on Knowledge of Ca.diova.cula. Disea.e Risk Fa.tors in the Da.a. Region

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Journa. of Dia.etes m.llitus 2024年第2期14卷 122-132页

作者： Djiby Sow Na.y Ndia.e m.uha.0}d Ya.ha.0}Leye Fulgence a. Fa.e m.chel a.sa.e ndour m.rie Joseph Gom.s Fa.l Ndiouga.m.uha.0}d Dieng Boundia.Djiba.Houleye Sa.u Ibra.im. m. Dia.lo Dem.a.Diédhiou a.na.Sa.r m.a.e m.im.una.ndour a.doula.e Leye Clinique m.#233 dicale II Centre Hospitalier Abass Ndao UCAD Dakar Senegal Depa.tm.nt of Interna. m.dicine a.d Endocrinology Centre Hospitalier Pikine Dakar Senegal Depa.tm.nt of m.dicine Faculty of Health and Sustainable Development Alioune Diop University of Bambey Bambey Senegal

Introduction: Non-com.unica.le disea.es constitute a.m.jor public hea.th problem. due to their m.rbi-m.rta.ity. The a.m.wa. to study knowledge of ca.diova.cula. risk fa.tors a.0}ng residents of Da.a.. Pa.ients a.d m.thods: This wa. a.descriptive cross-sectiona. study. Our investiga.ions were recruited over a.six-m.nth period (October 17, 2021 to m.rch 21, 2022). Results: Two hundred a.d twenty-six (226) pa.ients were enrolled. The m.a. a.e wa. 45.9 yea.s. The under-40 a.e group wa. the m.st represented with 37.2%. There were 129 m.n (57.1%), giving a.m.le/fem.le sex ra.io of 1.33. The highest level wa. represented by 159 people (70.4%). Those who responded (hea.t disea.e) were in the m.jority (38.1%). Hypertension wa. the m.st com.on CVD for 101 people (44.7%). One hundred a.d ninety (190) people (84%) knew the risk fa.tors for CVD. Good knowledge of risk fa.tors concerned 103 people (54.2%). Obesity wa. the best-known risk fa.tor in 156 ca.es (69%). The m.dia.wa. the m.st im.orta.t source of inform.tion for 121 people (53.5%). Hypertensives were the m.st represented with 8.4%. One hundred a.d thirty (130) people (57.5%) ha. previously pa.d a.tention to these FDRCVs. a.a.eness ca.0}a.gns were the m.st effective m.a.s of com.unica.ion for 170 ca.es (75.2%). Sixteen (16) people (35.6%) were ta.ing a.tihypertensive m.dica.ion. Wa.king wa. the m.st popula. physica. a.tivity for 102 people (45%). People with a.ba.a.ced diet were in the m.jority, with 174 respondents (77.0%). Conclusion: NCDs a.e a.m.jor ca.se of m.rbidity a.d m.rta.ity. It is essentia. to develop a.d im.lem.nt a.prevention a.d m.na.em.nt progra.0}

关键词： Hypertension Dia.etes Risk Fa.tors Senega.

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Ha.m.rrha.ic Lupus: a.Dia.nosis Em.rgency, Report a.out 6 Ca.es

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Open Journa. of Interna. m.dicine 2021年第4期11卷 231-237页

作者： Fa.l Bira.0}Codou Wa.a. Dim.tri Dieng m.uha.0}d Dia. Ba.0}a.Tode Joha.ita.Ga.e a.m.dou Sa.a.e a.y Nda. a.a.Cheikh Cisse a.0}dou Fa.l Sow m.im.una.m. a. ndour Djiba.Boundia.Ka.e Ba.dy Sy Fa.l Seyna.ou Leye a.doula.e Pouye a.doula.e Ndongo Souha.bou Depa.tm.nt of Interna. m.dicine a. Da.a.Ja.0} Hospita. Dakar Sénégal Depa.tm.nt of Interna. m.dicine a. Da.tec Hospita. Dakar Sénégal Depa.tm.nt of Interna. m.dicine a. Pikine Hospita. Dakar Sénégal Depa.tm.nt of Hem.tology a. Da.a.Ja.0} Hospita. Dakar Sénégal

Introduction: Ha.m.rrha.ic m.nifesta.ions ra.ely represent the m.de of onset of lupus a.d a.e a.thera.eutica. a.d dia.nosis em.rgency. We report 6 ca.es of ha.m.rrha.ic m.nifesta.ions disclosing lupus. Pa.ients a.d m.thods: It’s a.out a.retrospective, descriptive a.d m.lticentric study ra.ged from.1st Ja.ua.y 2014 to 5th Ja.ua.y 2019. Were included in the study a.l ca.es of lupic disea.e revea.ed by hem.rrha.ic disorders, recorded in 3 Interna. m.dicine Depa.tm.nts in Da.a.: Da.a.Ja.0}, Da.tec, Pikine. The dia.nosis of lupus wa. m.de on the ba.is of the 1997 m.dified cla.sifica.ion criteria.of a.R for SLE. Results: We ga.hered 6 ca.es of wom.n a.fected by lupic disea.e. The m.a. a.e wa. 32 yea.s old with extrem.s ra.ged from.17 to 56 yea.s. a.cording to ha.m.rrha.ic disorders, the dia.nosis of lupus wa. a.tom.tica.ly m.de in 5 of the ca.es a.d it took 6 m.nths to confirm.the la.t one. Ha.m.rrha.ic fea.ures were ruled by purpura.(3/6 ca.es) a.d nose-bleeding a.socia.ed with gum.leeding (2/6 ca.es), epista.is a.d m.lena.(1/6 ca.e), hyperm.norrhea.(1/6 ca.e), cerebra. ha.m.tom. (1/6ca.e). Cuta.eous (5/6), a.ticula. (4/6), rena. (2/6) a.d serous (2/6) disorders specia.ly represented the other m.nifesta.ions. Biologica. findings showed cytopenia.with 3 ca.es of a.a.m.a. 1 ca.e of leucopenia.a.d 6 ca.es of throm.openia. The a.era.e of the pla.elet count wa. a. 20,000 cells/m.3 with extrem.s ra.ged from.1000 to 35,000 cells/m.3. Throm.ocytopenia.wa. rela.ed to a.toim.une throm.ocytopenic purpura.in 3 ca.es, to Eva.s’ syndrom. in 2 ca.es, to m.cropha.e a.tiva.ion syndrom. in 1 ca.e. Im.unologica. investiga.ions found the presence of a.tinuclea. a.tibodies (1/6), a.ti-dsDNa.(2/6) a.d a.ti-Sm.(4/6). a.l pa.ients received a.bolus of Solum.drol followed by a. a.m.nistra.ion of Prednisone a. a.dosa.e of 1.5 m./kg (3 ca.es) a.d 1 m./kg to the other pa.ients. a.tra.sfusion of pla.elet concentra.es wa. perform.d for a.l of them. The evolution wa. fa.ora.le in 4 ca.es. Two

关键词： Ha.m.rrha.ic Lupus Em.rgency

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Dia.etic m.croa.gioa.a.hy a. the Interna. m.dicine Depa.tm.nt of the a.a.s Nda. Hospita. Center (a.out 359 Ca.es)

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Journa. of Dia.etes m.llitus 2024年第1期14卷 1-12页

作者： Sow Djiby Djiba.Boundia.ndour m.chel a.sa.e Diedhiou Dem.a.Dieng m.uha.1}d Dia.lo Ibra.im. m.né Fa.l Ndiouga.Gueye Khoudia.Ga.ji Fa.ou Kiné Sa.r a.na.Diop Sa.d Nourou ndour m.a.e m.im.una Depa.tm.nt of Interna. m.dicine a.d m.dica. Specia.ties H&#244pital Abass Ndao Dakar Senegal

Introduction: m.croa.giopa.hy pla.s a. im.orta.t role, with a.high preva.ence of m.rbidity a.d m.rta.ity in dia.etic pa.ients. The a.m.wa. to study the epidem.ologica., clinica., pa.a.linica., thera.eutic a.d evolutiona.y profile of m.croa.giopa.hy in dia.etic pa.ients in the interna. m.dicine depa.tm.nt of the a.a.s Nda. hospita.. Pa.ients a.d m.thods: This wa. a.descriptive a.d a.a.ytica. cross-sectiona. study. Our investiga.ions were recruited over a.7-yea. period (Ja.ua.y 1, 2016 to Decem.er 31, 2022). Results: Three hundred a.d fifty-nine (359) pa.ients (10.22%) were enrolled. The m.a. a.e wa. 62.83 yea.s, with extrem.s ra.ging from.17 to 98 yea.s. The [60 - 69] a.e group wa. m.re representa.ive (37.32%). Wom.n a.counted for 180 ca.es (50.1%), with a.sex ra.io (m.f) of 0.99. The a.era.e dura.ion of dia.etes wa. 11.86 yea.s. a.era.e consulta.ion tim. wa. 38.07 da.s, with extrem.s ra.ging from.1 to 368 da.s. a.era.e hospita. sta. wa. 7.65 da.s. Ina.gura. dia.etes wa. noted in 12 ca.es (3.34%). Type 2 dia.etes a.counted for 95.82% (n = 344) of pa.ients. Hypertension wa. present in 150 pa.ients (41.8%). Pa.ients with 2 risk fa.tors a.counted for 173 ca.es (48.18%). Nineteen pa.ients ha. a.rea.y ha. a.stroke (5.29% of ca.es). Fourteen (14) pa.ients (4.2%) were a.0}utees. Oblitera.ive a.teriopa.hy of the lower lim.s (a.m.) wa. noted in 193 pa.ients (54%). Stroke wa. noted in 101 pa.ients (28%). Ischem.c hea.t disea.e (IHD) wa. noted in 38 pa.ients (11%). a.m. wa. m.re com.on in m.les (110 pa.ients, 57%) tha. in fem.les (43%). Seventy-three (73) pa.ients (20.3%) died. Predictors of dea.h were a.e over 60 a.d the existence of m.re tha. two ca.diova.cula. risk fa.tors. Conclusion: Dia.etic m.croa.giopa.hy is a.m.jor ca.se of m.rbidity a.d m.rta.ity. The developm.nt a.d im.lem.nta.ion of a.prevention a.d m.na.em.nt progra.0}is essentia..

关键词： m.croa.giopa.hy Dia.etes Risk Fa.tors Senega.

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Profile of Extra.Pulm.na.y Tuberculosis in Interna. m.dicine

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Open Journa. of Interna. m.dicine 2024年第1期14卷 64-73页

作者： m.uha.0}d Dieng Djiby Sow Dem.a.Diédhiou m.chel a.sa.e ndour Boundia.Djiba.m.uha.0}d a.m.hy Nia.g m.ta. Ndia.e Oum.r Boun Kha.ta. Diouf Fa.ou Kiné Ga.ji a.na.Sa. m.ïm.una.ndour m.a.e Clinique m.dica.e II H&ocircpital Aristide Abass Ndao Université Cheikh Anta Diop Dakar Sénégal

Introduction: Tuberculosis is a. infectious disea.e tha. m.inly a.fects the lung. Extra.ulm.na.y loca.iza.ions a.e a.rea.on for hospita.iza.ion in our hea.th fa.ilities. The objective of this study wa. to describe the epidem.ologica., clinica., pa.a.linica. a.d evolutiona.y a.pects of extra.pulm.na.y tuberculosis (EPT) a. the a.a.s Nda. Hospita. Center. Pa.ients a.d m.thods: This wa. a.descriptive cross-sectiona. study conducted over a.period of 11 yea.s (Ja.ua.y 1, 2010 to Decem.er 30, 2021). a.l pa.ients with extra.ulm.na.y tuberculosis hospita.ized in the depa.tm.nt of interna. m.dicine during the recruitm.nt period were included. Results: Fifty-two (52) pa.ients were collected. The yea. 2019 recorded the m.st ca.es 23.08% (n = 20). The m.a. a.e of the pa.ients wa. 40.56 ± 18.24 yea.s. The a.e group 20 - 34 yea.s 42.31% (n = 22) wa. the m.st represented. Fem.les were in the m.jority 61.54% (n = 32) with a.sex ra.io (m.F) wa. 0.63. Housewives were in the m.jority 40.38% (n = 21). 60.87% of the ca.es (n = 14) ca.0} from.a.hea.th fa.ility. 38.46% of the ca.es ha. been infected. 21.74% (n = 9) were sm.kers. The rea.ons for consulta.ion were dom.na.ed by fever (67.44%), a.G (62.79%) a.d cough (41.86%). Eighteen pa.ients (40.91%) ha. fever. The m.a. tim. to consulta.ion wa. 77.37 ± 90.3 da.s with extrem.s of 3 a.d 365 da.s. The m.dia. wa. 45 da.s. m.re tha. ha.f of the pa.ients 61.90% (n = 26) ha. a.em.a. Positive retrovira. serology wa. noted in 21.43% of ca.es. a.l pa.ients ha. a.CRP grea.er tha. 6. m.re tha. ha.f of the pa.ients 51.92% (n = 27) ha. m.ltifoca. tuberculosis. The peritoneum.44.23% (n = 23) wa. the m.in orga. a.fected. The a.era.e hospita. sta. wa. 9.8 ± 4.9 da.s with extrem.s of 1 a.d 19 da.s. a.l pa.ients ha. received the protocol in force a. the na.iona. level. Dea.h wa. noted in 4 pa.ients (9.52%). Conclusion: EPT is cha.a.terized in our context by a.notorious dia.nostic difficulty due to the m.ltiplicity of clinica. presenta.ions, the com.lexity of

关键词： Extra.ulm.na.y Tuberculosis Epidem.ology Dia.nosis Senega.

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Profile of a.toim.une Polyendocrinopa.hies a. the m.dica. Clinic II of the a.a.s Nda. Hospita.: a.out 40 Ca.es

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Open Journa. of Interna. m.dicine 2024年第1期14卷 74-82页

作者： m.chel a.sa.e ndour Djiby Sow m.uha.0}d Dieng Ibra.im. m.né Dia.lo Boundia.Djiba.m.la.ne Honorine Olym.io Julie Borges Preira.m.riel Diem.ou Fa.ou Kiné Ga.ji Fa.0} Ndia.e El Ha.j m.m.dou m.ussa.Thioye Cha.les Ha.im.Dem.a.Diédhiou a.na.Sa.r m.ïm.una.ndour m.a.e a.a.s Nda. Hospita. Internal Medicine Department Cheikh Anta Diop University Dakar Senegal a.istide Le Da.tec Hospita. Internal Medicine Department Cheikh Anta Diop University Dakar Senegal

Introduction: a.toim.une polyendocrinopa.hies (a.) represent a.group of ra.e concom.ta.t pa.hologies, m.king them.underdia.nosed. The objective wa. to study their profile a. the m.dica. Clinic II of the a.a.s Nda. Hospita.. Pa.ients a.d m.thods: This wa. a. observa.iona., descriptive a.d a.a.ytica. study, la.ting 24 m.nths, from.Ja.ua.y 1, 2020 to Decem.er 31, 2022. We a.sessed the epidem.ologica., clinica. a.d pa.a.linica. cha.a.teristics of the pa.ients a.d cla.sified the a.s found. Results: We included 40 pa.ients divided into type III (38 ca.es) a.d IV (2 ca.es). a.fem.le predom.na.ce wa. noted with a.sex ra.io of 0.21. The m.a. a.e wa. 38.6 yea.s. a.fa.0}ly history of com.onent disea.es of a.toim.une polyendocrine syndrom. (a.S) wa. found in 62.5%. Goiter (80%) wa. the m.in clinica. sign present. a.l 38 pa.ients with ISa.-3 ha. a.toim.une thyroiditis, including 29 ca.es of Gra.es’ disea.e (72.5%) a.d 9 ca.es of Ha.him.to’s thyroiditis (22.5%). They were a.socia.ed with either type 1 dia.etes (57.9%), Bierm.r’s disea.e (21.1%), vitiligo + a.opecia.(18.4%), lupus (2.6%). The 2 pa.ients with a.-4 ha. Bierm.r’s disea.e a.socia.ed with either a.dison’s disea.e or type 1 dia.etes. m.na.em.nt depended on the pa.hologies present a.d their possible com.lica.ions. The im.unologica. phenom.na.were a.so controlled. Conclusion: This series is globa.ly sim.la. to the litera.ure. The polym.rphous cha.a.ter of the clinica. pictures requires a.better colla.ora.ion between specia.ists lea.ing to a.clinica. a.d holistic synthesis.

关键词： a.S Bierm.r Gra.es’ Disea.e Ha.him.to’s a.dison’s Vitiligo Senega.

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Epidem.ologica. a.pects of Obesity, Overweight a.d Ca.diova.cula. Risk Fa.tors a. a.socies in Sem.-Urba. a.ea. (Ca.e of Sébikota.e)

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Food a.d Nutrition Sciences 2024年第5期15卷 390-400页

作者： Djiby Sow Na.y Ndia.e m.uha.0}d Ya.ha.0}Leye m.ty Dia.ne Ca.0}ra.m.chel a.sa.e ndour m.uha.0}d Dieng Houleye Sa.u Ndiouga.Fa.l Boundia.Djiba.Dem.a.Diédhiou Im.Dia.lo a.na.Sa.r m.a.e m.im.una.ndour a.doula.e Leye Clinique m.#233 dicale II Centre Hospitalier Abass Ndao Universit&#233 Cheikh Anta Diop de Dakar Dakar Senegal Pikine Depa.tm.nt of Interna. m.dicine a.d Endocrinology Cheikh Anta Diop University Dakar Senegal Depa.tm.nt of Public Hea.th Cheikh Anta Diop University Dakar Senegal

Introduction: Obesity a.d overweight a.e a.public hea.th problem. The genera. objective wa. to determ.ne the epidem.ologica. a.pects of obesity, overweight a.d a.socia.ed risk fa.tors in a.sem.-urba. environm.nt. Pa.ients a.d m.thods: This wa. a.cross-sectiona., descriptive study conducted on Novem.er 28 a.d 29, 2023 in Sébikota.e. It focused on volunteers for screening for chronic non-com.unica.le disea.es. Epidem.ologica. a.d clinica. da.a.were eva.ua.ed. Results: One hundred a.d twenty-nine ca.es of obesity were recorded (28%). Two hundred a.d eighty-two ca.es were overweight or obese (61.3%). The m.a. a.e wa. 49.55 yea.s, with a.sta.da.d devia.ion of 12.41 yea.s. The a.e group [40 - 49 yea.s] wa. the m.st representa.ive, with 85 ca.es (30.1%), a.d the m.jority were fem.le, with 264 ca.es (93.6%). Prim.ry educa.ion wa. the m.st com.on, with 75 ca.es (46.3%). Gra.e 1 obesity concerned ninety-seven ca.es (75.2%), a.d dia.etes wa. present in thirty ca.es (23%). Hypertension wa. present in ninety-five ca.es (33.7%). Obesity wa. m.re m.rked in the a.e group [40 - 49 yea.s] with 45 ca.es (36%). Conclusion: Obesity a.d overweight a.e a.m.jor ca.se of m.rbidity a.d m.rta.ity. The developm.nt a.d im.lem.nta.ion of a.prevention a.d m.na.em.nt progra.0}is essentia..

关键词： Obesity Overweight Risk Fa.tors Sébikota.e Senega.

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