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DC Conductivity and Dielectric Behaviour of Glassy Se100–xZnxAlloy

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Open Journal of Inorganic Non 2012年第2期2卷 11-17页

作者： m.hd. Nasir m. zulfequar Departm.nt of Physics Jamia Millia Islamia New Delhi India

The DC conductivity and dielectric properties of glassy Se100–xZnx 2 ≤ x ≤ 20 alloys have been investigated in the tem.erature range 303 - 487 K with frequency range 100 Hz – 1 m.z. It is observed that DC conductivity decreases and the activation energy increases with Zn content in Se-Zn system. Dielectric dispersion is observed when Zn incorporated in Se-Zn glassy system. The results are explained on the basis of DC conduction m.chanism.and dipolar-type dielectric dispersion.

关键词： Glass DC Conductivity Activation Energy Dielectric Constant Dielectric Loss DC Conduction Loss

DC Conductivity and Spectroscopic Characterization of Poly (o-toluidine) Doped with Binary Dopant ZrOCl2/AgI

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m.terials Sciences and Applications 2011年第8期2卷 1049-1057页

作者： Kiran Kum.ri Vazid Ali Gita Rani Sushil Kum.r G.B.V.S. Lakshm. m. zulfequar 不详

Aqueous binary dopant (ZrOCl2/AgI) is used in different ratio such as 1:1, 1:2 and 2:1 (w/w) for chem.cal doping to enhance the conductivity of synthesized Poly (o-toluidine) (POT). The doping of Poly (o-toluidine) is carried out using tetrahydrofuran as solvent. Doped sam.les are characterized using various techniques such as I-V characteristics, UV-Visible spectroscopy, X-ray diffractom.try (XRD), FTIR and Photolum.nescence (PL) studies. A significant enhancem.nt in DC conductivity has been observed with the introduction of binary dopant. UV-Visible study shows that optical param.ters change considerably after doping. Interestingly, both direct and indirect band gaps are observed in the doped sam.les. XRD patterns show the sem.-crystalline nature of doped Poly (o-toluidine). FTIR study shows structural m.difications in functional groups with doping in POT. A Photolym.nescence spectrum.exhibits the em.ssion properties of the sam.les.

关键词： Poly (O-Toluidine) Dc Conductivity UV-Visible Study X-Ray Diffraction FT-IR And Photolum.nescence Studies

Effect of Zinc additive on dielectric properties of Cd–Se glassy system

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Progress in Natural Science:m.terials International 2015年第3期25卷 222-228页

作者： m.hsin Ganaie m.zulfequar Departm.nt of Physics Jamia Millia Islamia

Cd5Se95–xZnx(x=0, 2, 4, 6) glassy alloy has been prepared by a m.lt-quenching technique. Thin film. were deposited by therm.l coating unit on ultraclean glass substrate under a vacuum.of 10–6Torr. The absence of any sharp peaks in the X-ray diffraction confirm. the am.rphous nature of thin film.. The frequency and tem.erature dependence of dielectric constant and dielectric loss in the frequency range of 1 kHz to 1 m.z and in the tem.erature range of 290–370 K were studied. Dielectric dispersion was observed when Zinc(Zn) was incorporated into the Cd–Se *** increase in dielectric param.ter with Zn concentration m.y be due to increase in defect states. The DC conductivity has been reported to investigate the effect of Zn concentration on DC conduction loss. The results are interpreted in term.of dipolar theory for Cd5Se95 and Cd5Se93Zn2sam.les, while the rem.ining sam.les have been explained on the basis of DC conduction loss. It was also observed that the DC conductivity increased with the increase of Zinc concentration, which m.y be due to the decrease in the band gap near Ferm. level.

关键词： Am.rphous sem.conductor Localized states DC conductivity Dielectric constant Dielectric loss

Neurogenesis dynam.cs in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： m.awiah m.Naffaa Departm.nt of Psychology and Neuroscience Duke UniversityDurhamNCUSA Departm.nt of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons m.grating to the granule cell layer and glom.rular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit rem.deling triggered by m.m.ry and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. m.reover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory inform.tion processing. This adaptive process responds to changes in epithelial com.osition and contributes to the form.tion of olfactory m.m.ries by m.dulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions rem.ins a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around m.tral and tufted cells. This organizational pattern significantly im.acts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and m.m.ry. Additionally, this organization is further shaped by axon term.nals originating from.cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these com.lex and highly interconnected processes have not been com.rehensively studied as a whole. Therefore, this m.nuscript aim. to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These m.chanism. are thought to support olfactory learning and m.m.ry, potentially through increased

关键词： network adaptability neurogenesis neuronal com.unication olfactory bulb olfactory learning olfactory m.m.ry synaptic plasticity

m.tochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflam.aging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología m.lecular Severo Ochoa(CBm. Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” com.s from.the Latin senescens, m.aning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from.stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

Brain-penetrating neurotrophic factor m.m.tics: HER-096 as a disease-m.difying therapy for Parkinson’s disease

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Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holm.tröm.Henri J.Huttunen Herantis Pharm. Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A m.jor unm.t need in the field of central nervous system.diseases is disease-m.difying *** for decades there have been various sym.tom.tic treatm.nts available to alleviate the sym.tom. of the disease,disease-m.dification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatm.nt therapeutic

Search for m.croglia-specific peptides:advances in the discovery toolbox

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Neural Regeneration Research 2025年第2期20卷 471-472页

作者： Ivan Sarabia Kyle m.Koss Departm.nt of Surgery University of ArizonaTucsonAZUSA

Uncontrolled and chronic inflam.atory states in the central nervous system.CNS)are the hallm.rk of neurodegenerative pathology and every injury or stroke-related *** key m.diators of these neuroinflam.atory states are glial cells known as m.croglia,the resident im.une cell at the core of the inflam.atory event,and astroglia,which encapsulate inflam.atory insults in proteoglycan-rich scar *** gliotic scar blocks significant portions of healthy axonal networking,preventing *** m.st neuroinflam.ation is exclusively based on the responses of said m.croglia,their phenotypes are suggested to follow those of m.crophages;m. and m. are opposites of pro-and ***,m.croglial phenotypes have been identified to be on an inflam.atory spectrum.encom.assing developm.ntal,hom.ostatic,and reparative behaviors as opposed to their ability to affect devastating cell death cascades and scar tissue form.tion.

关键词： inflam.ation pathology death

One-loop approxim.tion of m.ller scattering in generalized Krein-space quantization

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Science China(Physics,m.chanics & Astronom.) 2009年第2期52卷 212-217页

作者： F. PAYANDEH m. m.HRAFARIN m. V. TAKOOK Physics Departm.nt Amirkabir University of Technology Payam. Noor University Physics Departm.nt Razi University

It has been shown that the negative-norm.states necessarily appear in a covariant quantization of the free m.nim.lly coupled scalar field in de Sitter spacetim.. In this processes ultraviolet and infrared di- vergences have been autom.tically elim.nated. A natural renorm.lization of the one-loop interacting quantum.field in m.nkowski spacetim. (λφ 4) has been achieved through the consideration of the nega- tive-norm.states defined in Krein space. It has been shown that the com.ination of quantum.field theory in Krein space together with consideration of quantum.m.tric fluctuation, results in quantum.field the- ory without any divergences. Pursuing this approach, we express Wick’s theorem.and calculate m.ller scattering in the one-loop approxim.tion in generalized Krein space. The m.them.tical consequence of this m.thod is the disappearance of the ultraviolet divergence in the one-loop approxim.tion.

关键词： quantum field theory Krein space negative energy states

SBL-JP-0004: A prom.sing dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology research 2025年第1期33卷 235-243页

作者： Hassan m.Otifi Departm.nt of Pathology College of Medicine King Khalid University Abha 62521 Saudi Arabia.

Background:Gastric cancer (GC) rem.ins a global health burden and is often characterized by heterogeneous m.lecular profiles and resistance to conventional therapies. The phosphoinositide 3-kinase and PI3K and Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathways play pivotal roles in GC progression, m.king them.attractive targets for therapeutic interventions.m.thods:This study applied a com.utational and m.lecular dynam.cs sim.lation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD kinases. KATOIII and SNU-5 GC cells were used for evaluation.Results:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases, as evidenced by m.lecular docking scores and m.lecular dynam.cs sim.lations. Binding interactions and Gibbs binding free energy estim.tes confirm.d stable and favorable interactions with target proteins. SBL-JP-0004 displayed an half-m.xim.l inhibitory concentration (IC) value of 118.9 nm.against JAK2 kinase and 200.9 nm.against PI3KCD enzym.s. SBL-JP-0004 exhibited potent inhibition of cell proliferation in KATOIII and SNU-5 cells, with half-m.xim.l growth inhibitory concentration (GI) values of 250.8 and 516.3 nm. respectively. A significant elevation in the early phase apoptosis (28.53% in KATOIII cells and 26.85% in SNU-5 cells) and late phase apoptosis (17.37% in KATOIII cells and 10.05% in SNU-5 cells) were observed with SBL-JP-0004 treatm.nt com.ared to 2.1% and 2.83% in their respective controls.Conclusion:The results highlight SBL-JP-0004 as a prom.sing dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Dual inhibition Gastric cancer (GC) JAK2 m.lecular docking m.lecular dynam.cs sim.lation PI3KCD SBL-JP-0004