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Gravitational Space-Tim. Quantization for Charged Worm.oles and the Diophantine Uncertainty Relation

Journal of m.dern Physics 2020年第11期11卷 1761-1778页

作者： yu. A. Khlestkov A. yu. Khlestkov P. yu. lukashin m. yu. lukashin N. yu. lukashina National Research Nuclear University (m.PhI) Moscow Russia

This research work proceeds from.the assum.tion, which was still considered by Einstein, that the quantization of gravity does not require additional external procedures: quantum.phenom.na can be a consequence of the properties of the universal gravitational interaction, which m.ps any physical field upon the space-tim. geom.try. Therefore, an attem.t is m.de in this research work to reduce the quantization of physical fields in GRT to the space-tim. quantization. Three reasons for quantum.phenom.na are considered: Partition of space-tim. into a set of unconnected Novikov’s R- and T-dom.ins im.enetrable for light paths;the set is generated by the invariance of Einstein’s equations with respect to dual m.ppings;The existence of electric charge quanta of worm.oles, which geom.trically describe elem.ntary particles in GRT. This gives rise to a discrete spectrum.of their physical and geom.tric param.ters governed by Diophantine equations. It is shown that the fundam.ntal constants (electric charge, rest m.sses of an electron and a proton) are interconnected arithm.tically;The existence of the so-called Diophantine catastrophe, when fluctuations in the values of physical constants tending to zero lead to fluctuations in the num.er of electric charges and the num.er of nucleons at the worm.ole throats, which tend to infinity, so that the product of the increm.nts of these num.ers by the increm.nt of physical constants form. a relation equivalent to the uncertainty relation in quantum.m.chanics. This suggests that space-tim. cannot but fluctuate, and, m.reover, its fluctuations are bounded from.below, so that all processes becom. chaotic, and the observables becom. averaged over this chaos.

关键词： Quantization of Gravitation Novikov’s R- and T-Dom.ins Diophantine Uncertainty Relations Discretization of Space-Tim.

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Entropy Production in a Non-Isolated Therm.dynam.c System.Taking into Account Regular Factors of Nonrandom.Nature

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Journal of m.dern Physics 2020年第3期11卷 343-354页

作者： A. yu. Khlestkov yu. A. Khlestkov N. yu. lukashina m. yu. lukashin P. yu. lukashin National Research Nuclear University m.PhI Moscow Russia

The work illustrates the im.ossibility of decreasing entropy in a strictly random.therm.dynam.c process in a non-isolated system.using the exam.le of heating a planet by solar radiation flux without and taking into account its rotation around its own axis. That is, the second law of therm.dynam.cs form.lated for isolated system. continues to govern such system.. We have shown that in order to achieve a stationary state at lower values of tem.erature and entropy far from.therm.dynam.c equilibrium.at a m.xim.m.of tem.erature and entropy, it is necessary to have regular factors of nonrandom.nature, one of which in this exam.le is the rotation of the planet around its own axis. This m.ans that the reason for the appearance of ordered structured objects in non-isolated therm.dynam.c system. is not the random.process itself, but the action of dynam.c control m.chanism., such as periodic external influences, nonlinear elem.nts with positive feedback, catalysts for chem.cal reactions, etc. We present the plots with dependences of tem.erature and entropy versus tim. in non-isolated system. with purely random.processes and in the presence of a control factor of non-random.nature-rotation.

关键词： Random Process Non-Isolated System. Entropy Ordered Structures Regular Factors of Non-Random Nature

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Gravitational Description and Graphics of a Worm.ole Structure—A Galactic m.gam.xim.n

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Journal of m.dern Physics 2019年第11期10卷 1299-1309页

作者： yu. A. Khlestkov N. yu. lukashina m. yu. lukashin P. yu. lukashin N. S. Trushkin National Research Nuclear University m.PhI Moscow Russia

Using the new exact solution of Einstein and m.xwell equations in the general relativity theory, they studied the internal structure of a geom.tric object with a nontrivial topology, the worm.ole. They showed that the galactic black hole recently discovered by astronom.rs and astrophysicists as the part of the Event Horizon Telescope project with the radius about 1016 cm.and the m.ss of about 1043 g can be a worm.ole alm.st neutralized in charge with param.ters close to critical—m.gam.xim.n, the radius of its neck curvature is equal to the so-called critical radius coinciding with half of the gravitational radius.

关键词： Gravitation Worm.ole Exact Solution m.gam.xim.n

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^(4)He m.nolayer on graphene:a quantum.m.nte Carlo study

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Com.unications in Theoretical Physics 2024年第9期76卷 149-157页

作者： S yu.m.Boninsegni Departm.nt of Physics University of AlbertaEdmontonAlbertaT6G 2H5Canada

We revisit the problem.of adsorption of a single^(4)He layer on graphene,focusing on the com.ensurate(C_(1/3))crystalline phase,specifically on whether it m.y possess a nonzero superfluid response,and on the existence of superfluid phases,either(m.tastable)liquid or vacancy-doped *** m.ke use of canonical quantum.m.nte Carlo sim.lations at zero and finite tem.erature,based on a realistic m.croscopic m.del of the *** results confirm.the absence of any superfluid response in the com.ensurate crystal,and that no therm.dynam.cally stable uniform.phase exists at lower *** evidence of a possibly long-lived,m.tastable superfluid phase at C_(1/3)coverage is ***,the results of ground-state projection m.thods and finite-tem.erature sim.lations are entirely consistent.

关键词： superfluidity low-dim.nsional system. quantum.m.nte Carlo helium supersolids

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The role of N-glycosylation in cancer

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Acta Pharm.ceutica Sinica B 2024年第3期14卷 1098-1110页

作者： yu.Lin David m.Lubm.n Departm.nt of Surgery University of Michigan Medical CenterAnn ArborMI 48109USA

Despite advances in understanding the developm.nt and progression of cancer in recent years,there rem.ins a lack of com.rehensive characterization of the cancer *** play an im.ortant role in m.dicine and are involved in various hum.n disease conditions including ***-m.ieties participate in fundam.ntal cancer processes like cell signaling,invasion,angiogenesis,and *** N-glycosylation significantly im.acts cancer processes and targeted therapies in ***,understanding N-glycosylation in a tum.r is essential for com.rehending disease progression and discovering anti-cancer targets and biom.rkers for therapy m.nitoring and *** review presents the fundam.ntal process of protein N-glycosylation and sum.arizes glycosylation changes in tum.r cells,including increased term.nal sialylation,N-glycan branching,and ***,the role of N-glycosylation in tum.r signaling pathways,m.gration,and m.tabolism.are *** and glycopeptides as potential biom.rkers for early detection of cancer based on site specificity have been ***,understanding and exploring the cancer glycoproteom.,along with its role in m.dicine,im.lication in cancer and other hum.n diseases,highlights the significance of N-glycosylation in tum.r processes,necessitating further research for potential anticancer targets and biom.rkers.

关键词： N-Glycosylated proteins Cancer signaling Cancer angiogenesis Cancer m.tabolism Cancer biom.rkers

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Identification of Proteins and Genes Associated with Hedgehog Signaling Pathway Involved in Neoplasm.Form.tion Using Text-m.ning Approach

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Big Data m.ning and Analytics 2024年第1期7卷 107-130页

作者： Nadezhda yu.Biziukova Sergey m.Ivanov Oga A.Tarasova Departm.nt of Bioinform.tics Institute of Biomedical ChemistryMoscow 119121Russia Departm.nt of Bioinform.tics Pirogov Russian National Research Medical UniversityMoscow 117997Russia

Analysis of m.lecular m.chanism. that lead to the developm.nt of various types of tum.rs is essential for biology and m.dicine,because it m.y help to find new therapeutic opportunities for cancer treatm.nt and cure including personalized treatm.nt *** of the pathways known to be im.ortant for the developm.nt of neoplastic diseases and pathological processes is the Hedgehog signaling pathway that norm.lly controls hum.n em.ryonic *** accum.lation of various types of biological data,including interactions between proteins,regulation of genes transcription,proteom.cs,and m.tabolom.cs experim.nts results,allows the application of com.utational analysis of these big data for identification of key m.lecular m.chanism. of certain diseases and pathologies and prom.sing therapeutic *** aim.of this study is to develop a com.utational approach for revealing associations between hum.n proteins and genes interacting with the Hedgehog pathway com.onents,as well as for identifying their roles in the developm.nt of various types of *** autom.tically collect sets of abstract texts from.the NCBI Pubm.d bibliographic *** recognition of the Hedgehog pathway proteins and genes and neoplastic diseases we use a dictionary-based nam.d entity recognition approach,while for all other proteins and genes m.chine learning m.thod is *** association extraction,we develop a set of sem.ntic *** com.lete the results of the text analysis with the gene set enrichm.nt *** identified key pathways that m.y influence the Hedgehog pathway and their roles in tum.r developm.nt are then verified using the inform.tion in the literature.

关键词： text-m.ning data m.ning Hedgehog pathway neoplastic processes enrichm.nt analysis pathology m.lecularm.chanism.

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Im.roved Quantile Convolutional and Recurrent Neural Networks for Electric Vehicle Battery Tem.erature Prediction

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Big Data m.ning and Analytics 2024年第2期7卷 512-530页

作者： Andreas m.Billert Runyao yu.Stefan Erschen m.chael Frey Frank Gauterin Karlsruhe Institute of Technology(KIT) Institute of Vehicle System TechnologyKarlsruhe 76131Germanyand also with Bayerische Motoren Werke(BMW)AGMunich 80788Germany Technical University of m.nich(TUm. Munich 80333Germany Bm. AG Munich 80788Germany KIT Institute of Vehicle System TechnologyKarlsruhe 76131Germany

The battery therm.l m.nagem.nt of electric vehicles can be im.roved using neural networks predicting quantile sequences of the battery *** work extends a m.thod for the developm.nt of Quantile Convolutional and Quantile Recurrent Neural Networks(nam.ly Q*NN).Fleet data of 225629 drives are clustered and balanced,sim.lation data from.971 sim.lations are augm.nted before they are com.ined for training and *** Q*NN hyperparam.ters are optim.zed using an efficient Bayesian optim.zation,before the Q*NN m.dels are com.ared with regression and quantile regression m.dels for four *** analysis of point-forecast and quantile-related m.trics shows the superior perform.nce of the novel Q*NN *** m.dian predictions of the best perform.ng m.del achieve an average Rm.E of 0.66°C and R^(2) of *** predicted 0.99 quantile covers 98.87%of the true values in the test *** conclusion,this work proposes an extended developm.nt and com.arison of Q*NN m.dels for accurate battery tem.erature prediction.

关键词： deep learning battery tem.erature convolutional and recurrent neural network quantile forecasting

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Interview with light-wave architect Jelena Vuckovic

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ADVANCED PHOTONICS 2024年第4期6卷 9-13页

作者： yu. m.ngjie Univ Southern Calif Viterbi Sch Engn Dept Elect & Comp Engn Los Angeles CA 90007 USA

m.ngjie yu.Hello,*** interview is organized by the journal Advanced *** today we're really honored and privileged to have Professor Jelena Vuckovic from.Stanford University here with us.I'm.from.University of Southern... 详细信息

关键词： wave interview light

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Oxygen uptake response to switching stairs exercise by non-param.tric m.deling

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Control Theory and Technology 2024年第2期22卷 315-325页

作者： Hairong yu.Chenyu.Zhang Kai Cao Ham.ah m.Alqudah Steven Weidong Su Key Laboratory of Child Developm.nt and Learning Science of m.nistry of Education and the School of Biological Science and m.dical Engineering Southeast UniversityNanjing210096JiangsuChina College of Artificial Intelligence and Big Data for m.dical Science Shandong First Medical University and Shandong Academy of Medical SciencesJinan250117ShandongChina Faculty of Engineering and Inform.tion Technology University of Technology SydneyUltimoNSW2007Australia

Oxygen uptake plays a crucial role in the evaluation of endurance perform.nce during exercise and is extensively utilized for m.tabolic assessm.nt. This study records the oxygen uptake during the exercise phase (i.e., ascending or descending) of the stair exercise, utilizing an experim.ntal dataset that includes ten participants and covers various exercise periods. Based on the designed experim.nt protocol, a non-param.tric m.deling m.thod with kernel-based regularization is generally applied to estim.te the oxygen uptake changes during the switching stairs exercise, which closely resem.les daily life activities. The m.deling results indicate the effectiveness of the non-param.tric m.deling approach when com.ared to fixed-order m.dels in term. of accuracy, stability, and com.atibility. The influence of exercise duration on estim.ted fitness reveals that the m.del of the phase-oxygen uptake system.is not tim.-invariant related to respiratory m.tabolism.regulation and m.scle fatigue. Consequently, it allows us to study the hum.ns’ conversion m.chanism.at different m.tabolic rates and facilitates the standardization and developm.nt of exercise prescriptions.

关键词： Non-param.tric m.deling Interval stair training exercise Kernel m.thod.Cardiorespiratory response Oxygen uptake

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Quantum.Spin Exchange Interactions to Accelerate the Redox Kinetics in Li–S Batteries

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Nano-m.cro Letters 2024年第5期16卷 370-383页

作者： yu.Du Weijie Chen yu.Wang yu. yu.Kai Guo Gan Qu Jianan Zhang Key Laboratory of Advanced Energy Catalytic and Functional m.terials Preparation of Zhengzhou City College of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001People’s Republic of China

Spin-engineering with electrocatalysts have been exploited to suppress the“shuttle effect”in Li–S *** selec-tion,spin-dependent electron m.bility and spin potentials in activation barriers can be optim.zed as quantum.spin exchange interactions lead-ing to a significant reduction of the electronic repulsions in the orbitals of ***,we anchor the m.Pc m.lecules on fluorinated carbon nanotubes(m.Pc@FCNT),which exhibits the single active m. sites with axial *** to the density functional theory calculations,the electronic spin polarization in m.Pc@FCNT not only increases the adsorption energy toward LiPSs interm.diates but also facilitates the tunneling process of electron in Li–S *** a result,the m.Pc@FCNT provides an initial capacity of 6.1 m.h cm.(-2) even when the high sulfur loading is 4.5 m. cm.(-2),and still m.intains 5.1 m.h cm.(-2) after 100 *** work provides a new perspective to extend the m.in group single-atom.catalysts enabling high-perform.nce Li–S batteries.

关键词： m.tal phthalocyanines Spin polarization Electrocatalysis Li–S batteries

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