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T Wave Am.litu.e Deviation as a Participation m.rker of Glycolysis in m.ocardial Repolarization

World Jou.nal of Cardiovascu.ar Diseases 2019年第5期9卷 343-353页

作者： m.khail u. Alekseev Aleksandr m. Alekseev Ju.enta Diagnostic Center Saint Petersburg Russia Tozka Diagnostics LLC Moscow Russia

Glu.ose m.tabolism.is essential for heart physiology, especially in ischem.c conditions. Anaerobic glycolysis participates along with aerobic fatty acid oxidation in generating energy su.ply, and the balance is shifted towards fatty acids. In the case of aerobic path restriction du. to coronary artery disease (CAD), this ratio changes. The aim.of the present research was to discover the aspects of glycolysis in cardiac electrophysiology.?We u.ilized the norm.lized (by average valu.) T wave am.litu.e deviation valu.s, nam.d the G criterion,?from.high-resolu.ion, 12-channel, 120-seconds-long electrocardiogram.,?which were obtained u.ing DACG technology. The calcu.ated G criterion allows a qu.ntitative assessm.nt of the ischem.c process and corresponds to the fu.ctional class (FC) according to the Canadian cardiovascu.ar classification. We exam.ned 22 healthy people and 79 proven CAD patients: 24 II FC, 40 III FC and 15 IV FC by original ECG and fasting blood su.ar tests. A strong correlation was fou.d between the average G criterion from.all 12 channels and the level of fasting blood su.ar (r = +0.88). In the control grou., blood su.ar levels were 91 ± 6.5 m./dl, II FC 103 ± 14.8 m./dl (p m./dl (p m.reover, the correlation factor (average G criterion and blood su.ar) was strong and positive in each grou.: control +0.72, II FC +0.83, III FC +0.76, and IV FC +0.89. For the first tim., heart electrical activity from.the ECG cu.ve was associated with high glu.ose level as one of the m.in CAD risk factors. The presence of su.h dependence of increased blood su.ar level from.the severity of the ischem.c process in the m.ocardiu.0}indicates that hyperglycem.c reaction is adaptive and can accelerate the anaerobic glycolysis for energy dem.nd com.ensation in heart m.scle.

关键词： Electrocardiogram T Wave Deviation Blood Su.ar Hyperglycem.a Glycolysis

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Poisson’s Ratio of Su.face Soils and Shallow Sedim.nts Determ.ned from.Seism.c Com.ressional and Shear Wave Velocities

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International Jou.nal of Geosciences 2014年第12期5卷 1540-1546页

作者： u. E. Essien A. O. Akankpo m. u. Igboekwe Departm.nt of Science Technology AkwaIbom State Polytechnic Ikot Osurua Nigeria Departm.nt of Physics University of Uyo Uyo Nigeria Departm.nt of Physics Michael Okpara University of Agriculture Umudike Nigeria

This paper presents the resu.ts of seism.c com.ressional, P- and shear, S-wave m.asu.em.nts carried ou. on the u.consolidated top-soil at the different locations of the stu.y area to determ.ne Poisson’s ratio. In this work, seism.c refraction data is u.ed to determ.ne Poisson’s ratio as an aid to engineering fou.dation. A 12-channel seism.graph with signal stacking ability was u.ed together with high frequ.ncy (100 Hz) geophones on the top-soil. The geophone intervals were set to 5 m.at the all locations. In all the locations, Vp/Vs ratio ranged from.1.0289 to 1.4185 for the top layer. Vp/Vs ratio in the second layer ranged from.1.0512 to 1.5834. The Poisson’s ratio for the first layer ranged from.-8.0324 to 0.2060. For the second layer, the Poisson’s ratio ranged from.-0.7567 to 0.1683. The valu.s of Vp/Vs ratio less than in the first layer and in som. locations in the second layer resu.ted in negative Poisson’s ratio. The low and negative valu.s of Poisson’s ratio are sym.tom.tic of occu.rence of ripable anisotropic m.terials in the locations where they occu., which su.gests that indicated average depth shou.d be rem.ved and refilled with geom.terials that m.y be resilient to carry engineering loads.

关键词： Seism.c Refraction Eket Vp/Vs Ratio Poisson’s Ratio

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Grou.dwater Recharge Throu.h Infiltration Process: A Case Stu.y of u.0}dike, Sou.heastern Nigeria

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Jou.nal of Water Resou.ce and Protection 2011年第5期3卷 295-299页

作者： m. u. Igboekwe Adindu.Ru.h 不详

Althou.h water is a renewable resou.ce for su.taining life and environm.nt, excessive pu.0}ing of grou.dwater resu.ts in the grou.d water table being depleted. The m.jor natu.al sou.ce of grou.dwater recharge is rainfall. In u.0}dike ju.t like m.ny other areas, the rate of natu.al recharge is lower than pu.0}ing rate. This is du. to increasing econom.c and agricu.tu.al activities and also u.banization. Over exploitation of grou.dwater is a threat to the water qu.lity and table and creates hydrological im.alance. This im.alance inclu.es degradation in hydrological and hydro-chem.cal characteristics of the aqu.fer. Artificial recharge of water table aqu.fers becom.s necessary to im.rove the hydrodynam.c conditions of grou.dwater. A drop in piezom.tric level can be rem.died by artificial recharge of grou.dwater throu.h infiltration process u.ing water from.dam., lakes, rivers, ru.off and sewage efflu.nt. Resu.ts of water table su.vey condu.ted at u.0}dike show that it peaks at 85m.(above sea level) before recharge and 95m.after recharge. The recharge of grou.dwater is basically throu.h rainfall and river water.

关键词： Artificial Recharge u.0}dike Infiltration Water Table

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Econom.cs of the plant species u.ed in hom.stead agroforestry on an offshore Sandwip Island of Chittagong District, Bangladesh

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Jou.nal of Forestry Research 2006年第4期17卷 285-288页

作者： R. u. m.m.n S. m. S. Hu.a m. K. Hossain B. m. Khan Institu.e of Forestry and Environm.ntal Sciences University of Chittagong Chittagong-4331 Bangladesh

This stu.y was perform.d in five villages of Sandwip u.azila, Chittagong district with a view to identify the tree resou.ces, u.ilization pattern and econom.c retu.n of m.jor fru.t and tim.er tree species. Inform.tion collected from.a total of 60 hou.eholds ranging from.m.rginal, sm.ll, m.diu.0}and large categories. Nu.0}er of plant species increased with the increase of hom.stead area. A total of 33 plant species were recorded from.the hom.garden, of which 19 were fru.t and 14 were tim.er tree species. Considerable nu.0}er of vegetables was also planted u.der the shade of the hom.stead trees. The investm.nt analysis showed that average benefit-cost ratios were greater than one, net present valu.s were positive and internal rate of retu.ns were m.re than 10%. Long term.investm.nt on horticu.tu.e and tim.er tree species is highly profitable if species like Artocarpu. heterophyllu., Cocos nu.ifera, Tectona grandis and Swietenia m.crophylla are planted.

关键词： Agroforestry Fru.t tree Tim.er tree Econom.cs Hom.garden Sandwip

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Synergy and translation of allogenic bone m.rrow stem.cells after photodynam.c treatm.nt of rheu.0}toid arthritis with tetra su.fonatophenyl porphyrin and TiO2 nanowhiskers

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Nano Research 2016年第11期9卷 3305-3321页

作者： Fawad u. Rehm.n Chu.qiu.Zhao Changyu.Wu.Xiaoqi Li Hu. Jiang m.tthias Selke Xu.m.i Wang State Key Laboratory of Bioelectronics School of Biological Science and Medical Engineering Southeast University Nanjing 210096 China Departm.nt of Chem.stry and Biochem.stry California State University Los Angeles CA 90032 USA Nanjing Foreign Langu.ge School Nanjing 210096 China

Rheu.0}toid arthritis （RA） etiology and am.lioration rem.ins a challenge in m.dern therapeu.ics. Herein, we explored the synergistic effect of allogenic bone m.rrow stem.cell （Bm.C） translation and photodynam.c treatm.nt of RA with tetra su.fonatophenyl porphyrin （TSPP） and TiO2 nanocom.osites as a new strategy for RA theranostics. The translation of Bm.Cs with m.RNAs into infected joints in long bones post-photodynam.c therapy is helpfu. for treating and u.derstanding RA pathophysiology. We observed that allogenic Bm.C translation com.ined with TSPP-TiO2 nanocom.osites can significantly （p 〈 0.01） lower the concentrations of seru.0}biom.rkers （tu.0}r necrosis factor-α and interleu.in-17） in a collagen indu.ed arthritis （CIA） m.rine m.del, both in vitro and in vivo, as well as im.rove other param.ters su.h as arthritis score, Bm.C cou.t, com.lete blood cou.t, and nu.0}ers of platelets, red blood cells, and white blood cells. m.reover, a flu.rescent TSPP in the feet or long bones and X-ray bioim.ging of RA joints revealed the clinical efficacy of Bm.Cs com.ined with TSPP-TiO2 nanocom.osites. m.croarray data analysis illu.trated that rnom.r-375-3p and rno-m.r-196b-3p were u.-regu.ated by approxim.tely 100-fold in the Bm.Cs of am.liorated RA post-photodynam.c therapy with TSPP-TiO2 nanocom.osites. Ou. stu.y not only su.gests a new approach for RA theranostics, bu. also helps in u.derstanding RA pathophysiology.

关键词： rheu.0}toid arthritis allogenic bone m.rrowstem.cells (Bm.Cs) tetra su.fonatophenyl porphyrin (TSPP)-TiO2nanocom.osites photodynam.c treatm.nt m.RNAs

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The Faddeev knots as stable solitons: Existence theorem.

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Science China m.them.tics 2004年第2期47卷 187-197页

作者： LIN Fanghu. & YANG YisongCou.ant Institu.e of m.them.tical Sciences, New York u.iversity, New York, New York 10012, u. S. A.School of m.them.tics, Institu.e for Advanced Stu.y, Princeton, New Jersey 08540, u. S. A. Departm.nt of m.them.tics, Polytechnic u.iversity, Brooklyn, New York 11201, u. S. A. Cou.ant Institu.e of m.them.tical Sciences New York University New York U S A School of m.them.tics Institute for Advanced Study Princeton U S A Departm.nt of m.them.tics Polytechnic University Brooklyn U S A

The problem.of existence of knot-like solitons as the energy-m.nim.zing configu.ations in the Faddeev m.del, topologically characterized by an Hopf invariant, Q, is considered. It is proved that, in the fu.l space situ.tion, there exists an infinite set S of integers so that for any m.∈ S, the Faddeev energy, E, has a m.nim.zer am.ng the class Q = m. in the bou.ded dom.in situ.tion, the sam. existence theorem.holds when S is the set of all integers. One of the im.ortant technical resu.ts is that E and Q satisfy the su.linear inequ.lity E ≤ C|Q|u.>3/4u.>, where C > 0 is a u.iversal constant, which explains why knotted (clu.tered soliton) configu.ations are preferred over widely separated u.knotted (m.ltisoliton) configu.ations when |Q| is su.ficiently large.

关键词： knots, Hopf invariant, m.nim.zation, solitons.

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Biological and m.chanical investigation of novel flax/silk protein-based nanofibrou. scaffold for bone regeneration

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Progress in Natu.al Science:m.terials International 2022年第4期32卷 443-455页

作者： m.Ram. u.Vijayalakshm. Departm.nt of Chem.stry School of Advanced Sciences Vellore Institute of Technology

The process of bone tissu. regeneration involves an intricate network of a biological m.crom.lecu.es that inclu.es proteins and peptides to su.port stim.lation and healing response. Here, we have fabricated a novel flaxseed/silk fibroin based(du.l protein) com.osite nanofibers u.ing β-TCP to im.rove the biological properties and prom.te cartilage tissu. regeneration along with a controllable rate of biodegradation. The physiochem.cal properties of PVA/β-TCP/FP:SF were characterized by FTIR, XRD, SEm. porosity, contact angle m.asu.em.nts and m.chanical evalu.tion etc. This stu.y dem.nstrates the biological perform.nce of the developed nanofibers by u.ing hem.com.atibility, biodegradation ability, and apatite deposition in stim.lated body flu.d. m.reover, the cell viability assay was perform.d on m.-63 osteoblast cells and long-term.antibacterial rate against E. coli and S. au.eu. was analysed. Docking resu.ts of flax protein and silk fibroin protein fu.ther confirm.d the stable m.des of intram.lecu.ar bonding and the m.st stable electrostatic valu.s u.ing theoretical calcu.ations. Taken together,the experim.ntal resu.ts proved that the du.l protein-based fibrou. scaffold was fou.d to be u.-regu.ated in term. of biological activity with enhanced cell adhesion and proliferation.

关键词： Flax protein Silk fibroin β-TCP Electrospinning Docking Bone regeneration

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Polar Du.ls of Rotors

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Acta m.them.tica Sinica,English Series 1996年第1期12卷 40-42页

作者： Ghandehari m. Departm.nt of m.them.tics Noval Postgradu.te School m.nterey, CA 93943 u. S. A.

Assu.0} K is a rotor in a regu.ar sim.lex of heihgt 1 in an n-dim.nsional Eu.lidean space. Let K~* denote the polar du.l of K. Then the volu.0} V(K~*) satisfies the inequ.lity V(K~*)≥(n+1)~nω_n, where ω_n denotes the volu.0} of an n-dim.nsional u.it ball. Equ.lity holds if and only if K is a ball centered at the centroid of the sim.lex.

关键词： Rotor Polar du.l Regu.or Sim.lex

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Fever assessm.nt in children u.der five: Are we following the gu.delines?

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World Jou.nal of Clinical Pediatrics 2024年第1期13卷 62-72页

作者： Hasan m.Isa Ahm.d J Isa m.rtadha A Alnasheet m.hm.od m.m.nsoor Departm.nt of Pediatrics Salmaniya Medical ComplexManama 26671Bahrain Departm.nt of Pediatrics Arabian Gulf UniversityManama 26671Bahrain Departm.nt of General Su.gery Salmaniya Medical ComplexManama 26671Bahrain

BACKGROu.D Fever is a com.on cau.e of m.dical consu.tation and hospital adm.ssion,particu.arly am.ng ***,the u.ited Kingdom.s National Institu.e for Health and Care Excellence(NICE)u.dated its gu.delines for assessing fever in children u.der five years of *** efficient assessm.nt and m.nagem.nt of children with fever are cru.ial for im.roving patient *** To evalu.te fever assessm.nt in hospitalized children and to assess its adherence with the NICE Fever in u.der 5s *** We condu.ted a retrospective cohort review of the electronic m.dical records of children u.der five years of age at the Departm.nt of Pediatrics,Salm.niya m.dical Com.lex,Bahrain,between Ju.e and Ju.y *** data,vital signs du.ing the first 48 h of adm.ssion,rou.e of tem.eratu.e m.asu.em.nt,and indications for adm.ssion were *** was defined according to the NICE *** children were divided into five grou.s according to their age(0-3 m.nths,>3-6 m.nths,>6-12 m.nths,>12-36 m.nths,and>36-60 m.nths).Patients with and withou. fever were com.ared in term. of dem.graphy,indication for adm.ssion,rou.e of tem.eratu.e m.asu.em.nt,and other vital *** with the NICE Fever in the u.der 5s gu.deline was *** com.liance was defined as>95%,partial com.liance as 70%-95%,and m.nim.l com.liance as≤69%.Pearson’sχ^(2),Stu.ent’s t test,the m.nn-Whitney u.test,and Spearm.n’s correlation coefficient(rs)were u.ed for *** Of the 136 patients reviewed,80(58.8%)were *** m.dian age at adm.ssion was 14.2[interqu.rtile range(IQR):1.7-44.4]m.nths,with the m.st com.on age grou. being 36-60 ***-six(26.4%)patients had fever,and 100(73.6%)were *** com.onest age grou. for febrile patients(>12-36 m.nths)was older than the com.onest age grou. for afebrile patients(0-3 m.nths)(P=0.027).The m.dian weight was 8.3(IQR:4.0-13.3)*** with fever had higher weight than those withou. fever[10.2(IQR:7.3-13.0)vs 7

关键词： Fever Pediatrics Adm.ssion patterns Tem.eratu.e m.asu.em.nt Gu.delines Bahrain

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Spanning Sim.licial Com.lex of Wheel Graph Wn

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Algebra Colloqu.u. 2019年第2期26卷 309-320页

作者： A. Zahid m.u. Saleem.A. Kashif m. Khan m.A. m.raj R. Irfan Departm.nt of m.them.ticsf u.iversity of Exlu.ation Lahore Pakistan u.iversity of m.nagem.nt and Technology Lahore Pakistan Departm.nt of m.them.tics University of Education Lahore Pakistan Departm.nt of m.them.tics COMSATS University Islamabad Sahiwal Campus Sahiwal Pakistan

In this paper, we explore the spanning sim.licial com.lex of wheel graph Wn on vertex set [n]. Com.inatorial properties of the spanning sim.licial com.lex of wheel graph are discu.sed, which are then u.ed to com.u.e the f-vector and Hilbert series of face ring k[Δs(Wn)] for the spanning sim.licial com.lex Δs(Wn). m.reover, the associated prim.s of the facet ideal IF(Δs(Wn)) are also com.u.ed.

关键词： sim.licial com.lexes spanning trees spanning sim.licial com.lexes f-vectors Hilbert series vertex covers

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