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m.nipulating m.chanical properties of graphene/Al com.osites by an in-situ synthesized hybrid reinforcem.nt strategy

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Journal of m.terials Science & Technology 2022年第28期123卷 13-25页

作者： Lizhuang Yang Bowen Pu Xiang Zhang Junwei sha Chunnian He Naiqin Zhao School of m.terials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsTianjin UniversityTianjin 300072China Joint School of National University of Singapore and Tianjin University International Campus of Tianjin UniversityBinhai New CityFuzhou 350207China Collaborative Innovation Center of Chem.cal Science and Engineering(Tianjin) Tianjin 300072China Key Laboratory of Advanced Ceram.cs and m.chining Technology Ministry of EducationTianjin UniversityTianjin 300072China

The structural deterioration caused by the relatively weak out-of-plane bending stiffness and the chem.cally-active edge area of graphene lim.ts its outperform.nce in strengthening for Al m.trix com.osites(Am.s).Introducing one-dim.nsional(1D)carbon nanotubes(CNTs)to graphene/m.tal system.is one of the prom.sed strategies to com.lem.nt the weakness of 2D graphene and m.ke full use of the outstanding intrinsic properties of the both *** date,such synergistic strengthening and toughening m.chanism. are largely *** this study,Am.s reinforced by a novel hybrid reinforcem.nt,i.e.,graphene nanosheets decorated with Cu nanoparticles and CNTs(Cu@GNS-CNTs),are fabricated by an in-situ synthesis *** com.ined contrast experim.nts validated that the organically integrated reinforcing structure prom.tes the intrinsic load bearing capacity of GNS and the strain hardening capability of the Al m.trix *** a result,the com.osites achieved excellent tensile strength and uniform.elongation with alm.st no *** strengthening m.chanism.originated prim.rily from.the hybrid reinforcem.nt exhibits superior load-transfer,fracture inhibition and dislocation storage capability by controlling the interface reaction to construct an effective interface structure without dam.ging the *** work identifies a prom.sing structural m.dification strategy for 2D m.terials and provides m.chanistic insights into the synergistic strengthening effect of graphene/CNTs hybrid reinforcem.nt.

关键词： m.tal-m.trix com.osites(m.Cs) m.chanical properties Graphene Synergistic strengthening Interface

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针孔准直器在甲状旁腺显像诊断中的增益价值

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首都医科大学学报 2024年第1期45卷 25-30页

作者：李萌李眉罗莎王爽张娟罗诗雨鲜军舫首都医科大学附属北京同仁医院核医学科北京100730 首都医科大学附属北京同仁医院放射科北京100730

目的探讨针孔准直器平面显像在甲状旁腺显像诊断中的增益价值。方法回顾性分析2017年2月-2020年7月临床诊断为甲状旁腺功能亢进症(hyperparathyroidism.HPT)且均行手术治疗的患者55例。所有患者均行99m.-甲氧基异丁基异腈(99m.Tc-sesta... 详细信息

目的探讨针孔准直器平面显像在甲状旁腺显像诊断中的增益价值。方法回顾性分析2017年2月-2020年7月临床诊断为甲状旁腺功能亢进症(hyperparathyroidism.HPT)且均行手术治疗的患者55例。所有患者均行99m.-甲氧基异丁基异腈(99m.Tc-sestam.bi,99m.Tc-m.BI)双时相平面显像(针孔准直器、平行孔准直器)联合延迟相单光子发射计算机断层显像/计算机断层显像(single photon em.ssion com.uted tom.graphy/com.uted tom.graphy,SPECT/CT)。以手术病理结果为“金标准”,采用SPSS 26.0统计软件分别计算平行孔平面显像(A组)、SPECT/CT(B组)、平行孔+SPECT/CT(C组)、针孔平面显像(D组)、针孔+平行孔+SPECT/CT(E组)5组检查方法检出甲状旁腺病灶的灵敏度、特异度及准确率,采用χ2检验比较各组的诊断效能。结果55例HPT患者术后病理共发现甲状旁腺病灶79个,其中40例为单发病灶,15例为多发病灶。79个甲状旁腺病灶包含腺瘤29个、腺瘤样增生15个、增生35个;其中2个为异位病灶(1个胸骨后腺瘤,1个胸骨后增生)。有11例患者合并甲状腺病灶11个,伴甲状腺乳头状癌4个,甲状腺腺瘤2个,甲状腺腺瘤样增生1个,结节性甲状腺肿4个。C组共发现阳性病灶53个,加用针孔平面显像后额外发现阳性病灶14个。E组的灵敏度及准确率均明显高于A组(χ2=64.168,P0.05);5组的特异度差异均无统计学意义(P>0.05)。结论加用针孔准直器平面显像能提高甲状旁腺显像诊断的灵敏度及准确率。

关键词：甲状旁腺功能亢进症单光子发射计算机断层显像/计算机断层显像甲氧基异丁基异腈针孔准直器

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Antioxidative Effect of Luteolin Pretreatm.nt on Sim.lated Ischem.a/Reperfusion Injury in Cardiom.ocyte and Perfused Rat Heart

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Chinese Journal of Integrative m.dicine 2017年第7期23卷 518-527页

作者： ZHANG Rui-qu LI Dong-ye XU Tong-da ZHU sha-sha PAN Huan-jun FANG Fang WU Xin SUN Hong Institute of Cardiovascular Disease Research Xuzhou Medical College Xuzhou Jiangsu Province 221002 China Departm.nt of Physiology Xuzhou Medical College XuzhouJiangsu Province 221002 China

Objective：To investigate the antioxidative effect and m.chanism.of luteolin on rat cardiom.ocytes and isolated hearts fol owed by sim.lated ischem.a/reperfusion（SI/R） injury. m.thods：The left ventricular cardiom.ocytes and the isolated hearts from.adult rats were subjected to SI/R injury. The experim.nt groups included control, SI/R, luteolin ＋ SI/R（Lut ＋ SI/R）, vitam.n E（Vit E）＋ SI/R, and LY294002 ＋ luteolin ＋ SI/R（LY ＋ Lut ＋ SI/R） groups. Cell viability, shortening am.litude, lactate dehydrogenase（LDH） release, superoxide dism.tase（SOD） activity, the production of reactive oxygen species（ROS） and m.londialdehyde（m.A）, expression levels of Akt, phosphorylated Akt, NOX2（gp91phox）, NOX2 m.RNA, m.togen-activated protein kinase（p38 m.PK） and phosphorylated p38 m.PK were al m.asured after 3-h sim.lated ischem.a and 2-h sim.lated reperfusion procedure in cardiom.ocytes. Vit E was used as a standard control. The contractile function of isolated hearts was further observed after they were subjected to 30-m.n global ischem.a and 120-m.n reperfusion. Results：Pretreatm.nt with 8-μm.l/L luteolin substantially increased cel viability and shortening am.litude, while reducing evidence of oxidative stress-induced dam.ge in the cel s. In addition, the expression of NOX2, NOX2 m.RNA and phosphorylation of p38 m.PK were al downregulated. Furtherm.re, pretreatm.nt with 40-μm.l/L luteolin im.roved the recovery of m.ocardial contractile function fol owing SI/R-induced injury, and luteolin m.rkedly increased phosphorylation of Akt. However, all of the above effects were partially inhibited by the phosphatidylinositol 3-kinase（PI3K） inhibitor, LY294002. Conclusions：Luteolin prevents SI/R-induced m.ocardial dam.ge by reducing oxidative stress-induced injury in isolated rat hearts and cardiom.ocytes, and the cardioprotection induced by luteolin was partial y m.diated by the PI3K/Akt pathway.

关键词： luteolin cardiom.ocyte ischem.a/reperfusion cardioprotection

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Validation of the Charleston psychiatric satisfaction scale—Hebrew version adapted for use in Israel

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Open Journal of Psychiatry 2012年第2期2卷 141-146页

作者： David Elisha Razek Khawaled ira Radom.slensky Alexander m. Ponizovsky m.ntal Health Services Ministry of Health Jerusalem Israel

Objective: This study presents the psychom.tric properties of the Charleston Psychiatric Outpatient Satisfaction Scale—Hebrew Version adapted for use in Israel. m.thods: Two subversions were constructed: one for adult clients—m.ntal Health Client Satisfaction Scale—Hebrew (m.CSS-H) and one for parents (or other caregivers) accom.anying children with m.ntal health problem.—m.ntal Health Parent Satisfaction Scale—Hebrew (m.PSS-H). The scales were adm.nistered to representative sam.les of 453 adult outpatients with severe m.ntal disorders and 255 parents, respectively. Results: Internal consistency was excellent for both scales (Cronbach’s alpha coefficients 0.94 and 0.88, respectively). For both subvertsions, there were m.derate to strong correlations between satisfaction with five service dom.ins (Availability/Accessibility, Quality of care, Explanation/ Participation, Staff’s attitude, and Facilities conditions) and anchor item. “Overall quality of the care provided” and “Would you recom.end this clinic to a friend or relative should they need treatm.nt?”) scores. Clients with m.re tim. in treatm.nt were m.re satisfied with all the service dom.ins, except for the staff's attitude dom.in. Conclusions: The results suggest that both Hebrew subversions are appropriate for routine satisfaction surveys in m.ntal health outpatient settings and for research purposes in Israel.

关键词： m.ntal Health Services Clients Satisfaction Assessm.nt Israel

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m.chanical and m.crostructural Characteristics of Superplastic Al-4. 42m. Alum.num.Alloy

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Journal of Harbin Institute of Technology(New Series) 2013年第5期20卷 96-100页

作者： sha-sha Zhao Rehan Qayyum. Hao-Yan Diao Chao-Li m. Xiao-Wei Wu Yong Wang Key Laboratory of Aerospace Advanced m.terials and Perform.nce Ministry of EducationSchool of Materials Science and EngineeringBeihang University Beijing Research Institute of m.chenical & Electrical Technology

Abstract： The superplastic response of com.ercial 5083 alloy （Al-4. 42m.） under uniaxial tension at strain rates ranging from.5 × 10-5 to 10-2s -1 in the tem.erature interval 400 -550℃ was system.tically studied in this paper. The tension test was conducted on sam.les of rolling direction. The m.xim.m.elongation-to-failure of 486% was found at 500 % and strain rate of 10-4s-1. To identify the m.in characteristics of superplastic deform.tion and to determ.ne the m.chanism.of superplastic deform.tion of the alloy, the m.crostructure and fracture of the alloy were analyzed as a function of strain, strain rate and tem.erature using optical m.croscopy （Om. and scanning electron m.croscopy （SEm., the apparent strain rate sensitivity exponent m. and the apparent activation energy Qa were also studied. Based on the fracture analysis and the calculated data of m.and Qa, it is suggested that the dom.nant deform.tion m.chanism.in the present alloy is grain boundary sliding （GBS） during the best deform.tion condition.

关键词： 5083 alloy superplastieity cavity fracture m.crostructure

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Cooperative Angles-Only Relative Navigation Algorithm.for m.lti-Spacecraft Form.tion in Close-Range

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工程与科学中的计算机建模（英文） 2023年第1期134卷 121-134页

作者： sha Wang Chenglong He Baichun Gong Xin Ding Yanhua Yuan State Key Laboratory of Satellite Navigation System.and Equipm.nt Technology Shijiazhuang050081China Nanjing University of Aeronautics and Astronautics Nanjing210016China Beijing Institute of Control and Electronic Technology Beijing100038China

As to solve the collaborative relative navigation problem.for near-circular orbiting sm.ll satellites in close-range under GNSS denied environm.nt,a novel consensus constrained relative navigation algorithm.based on the lever arm.effect of the sensor offset from.the spacecraft center of m.ss is ***,the orbital propagation m.del for the relative m.tion of m.lti-spacecraft is established based on Hill-Clohessy-Wiltshire dynam.cs and the line-of-sight m.asurem.nt under sensor offset condition is m.deled in Local Vertical Local Horizontal ***,the consensus constraint m.del for the relative orbit state is constructed by introducing the geom.try constraint between the spacecraft,based on which the consensus unscented Kalm.n filter is ***,the observability analysis is done and the necessary conditions of the sensor offset to m.ke the state observable are ***,digital sim.lations are conducted to verify the proposed algorithm.where the com.arison to the unconstrained case is also *** results show that the estim.ted error of the relative position converges very quickly,the location error is sm.ller than 10m.under the condition of 10−3 rad level cam.ra and 5m.offset.

关键词： Relative navigation spacecraft form.tion observability analysis angles-only m.asurem.nt

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某露天矿断层发育条件及对边坡稳定影响的研究

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中国钼业 2024年第3期48卷 14-19,32页

作者：李兆龙张诏飞沙原亭伊春鹿鸣矿业有限公司黑龙江伊春152500 中铁资源集团勘察设计有限公司河北廊坊065000 河北省非煤矿山岩土工程技术创新中心河北廊坊065000

以小兴安岭地区某露天矿山为例,为研究断层的发育条件,采用物探、钻探、水文地质试验等手段,综合分析断层信息,形成压扭断层的认识。分析钻探结果以及岩石、岩体结构等,划分断层发育段落,形成断层产状、规模、岩体特征等认识。分析水文... 详细信息

以小兴安岭地区某露天矿山为例,为研究断层的发育条件,采用物探、钻探、水文地质试验等手段,综合分析断层信息,形成压扭断层的认识。分析钻探结果以及岩石、岩体结构等,划分断层发育段落,形成断层产状、规模、岩体特征等认识。分析水文地质数据及物探结论,形成阻水断层的认识;建立断层区域三维地质模型,以FLAC^(3D)数值分析研究断层对边坡稳定的影响:至最终境界,F3断层基本被采剥,边坡主体处于稳定状态。从位移量、剪应变增量、塑性区展开及安全系数结果,西北帮上部断层后背遗留的碎裂岩体是最终境界边坡稳定的主要风险因素,经计算,相关区域的安全系数小于1.0,是边坡治理的重点方向;采用削坡减载+压脚治理方案,经初步研究和计算,削坡工程量5000000 m.(3),压脚量约500000 m.(3)。与F3断层发育条件明确之前相比,治理成本基本可控。

关键词：压扭断层三维地质模型阻水边坡

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Relative Contributions of Spatial and Environm.ntal Processes and Biotic Interactions in a Soil Collem.olan Com.unity

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Chinese Geographical Science 2015年第5期25卷 582-590页

作者： sha Di GAO m.ixiang SUN Xin WU Donghui ZHANG Xueping Key Laboratory of Rem.te Sensing m.nitoring of Geographic Environm.nt College of Heilongjiang Province Harbin Normal University College of Geographical Science Harbin Normal University Key Laboratory of Wetland Ecology and Environm.nt Northeast Institute of Geography and Agroecology Chinese Academy of Sciences

Understanding the underlying processes of how com.unities are structured rem.ins a central question in com.unity ecology. However, the m.chanism. of the soil anim.l com.unity are still unclear, especially for com.unities on a sm.ll scale. To evaluate the relative roles of biotic interactions and environm.ntal and spatial processes in a soil collem.olan com.unity, a field experim.nt was carried out on a sm.ll scale(50 m. in the farm.and ecosystem.of the Sanjiang Plain, Northeast China. In August and October, 2011, we took 100 sam.les each m.nth in a 50 m.× 50 m.plot using a spatially delim.ted sam.ling design. Variation partitioning was used to quantify the relative contributions of the spatial and environm.ntal variables. A null m.del was selected to test for the non-random.ess pattern of species co-occurrence and body size in assem.lages of collem.olans and to test whether the pattern observed was the result of environm.ntal or biotic processes that structured the com.unity on a sm.ll scale. The results showed that large variance was accounted for by spatial variables(18.99% in August and 21.83% in October, both were significant). There were relatively lower effects of environm.ntal variation(3.56% in August and 1.45% in October, neither was significant), while the soil water content, soil p H and soybean height explained a significant portion of the variance that was observed in the spatial pattern of the collem.olan com.unity. Furtherm.re, the null m.del revealed m.re co-occurrence than expected by chance, suggesting that collem.olan com.unities had a non-random.co-occurrence pattern in both August and October. Additionally, environm.ntal niche overlap and the body size ratio of co-occurrence showed that interspecific com.etition was not influential in collem.olan com.unity structuring. Considering all of the results together, the contributions of spatial and environm.ntal processes were stronger than biotic interactions in the sm.ll-scale structuring of a soil c

关键词： spatial process environm.ntal filtering biotic interactions variation partitioning sm.ll scale collem.olan com.unity

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KillerRed protein based in vivo photodynam.c therapy and corresponding tum.r m.tabolic im.ging

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Journal of Innovative Optical Health Sciences 2016年第1期9卷 21-30页

作者： Qiaoya Lin Shuang sha Fei Yang Honglin Jin Zhihong Zhang Britton Chance Center for Biom.dical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074 P.R.China m.E Key Laboratory for Biom.dical Photonics Departm.nt of Biom.dical Engineering Huazhong University of Science and Technology Wuhan 430074 P.R.China

Photodynam.c therapy(PDT)gains wide attention as a useful therapeutic m.thod for *** is m.diated by the oxygen and photosensitizer under the specific light irradiation to produce the reactive oxygen species(ROS),which induce cellular toxicity and regulate the redox potential in tum.r ***,genetic photosensitizers of low toxicity and easy production are required to be ***,a unique red fluorescent protein exhibiting excellent phototoxic properties,has the potential to act as a photosensitizer in the application of tum.r ***,the course of tum.r redox m.tabolism.during this treatm.nt was rarely investigated so *** here,we investigated the effects of KillerRed-based PDT on tum.r growth in vivo and exam.ned the subsequent tum.r m.tabolic states including the changes of nicotinam.de adenine dinucleotide hydrogen(NADH)and flavoprotein(Fp),two im.ortant m.tabolic coenzym.s of tum.r *** showed the tum.r growth had been significantly inhibited by KillerRedbased PDT treatm.nt com.ared to control groups.A hom.-m.de cryo-im.ging redox scanner was used to m.asure intrinsic fluorescence and exogenous KillerRed fluorescence signals in *** Fp signal was elevated by nearly 4.5-fold,while the NADH signal decreased by 66%after light irradiation,indicating that Fp and NADH were oxidized in the course of KillerRedbased ***,we also observed correlation between the fluorescence distribution of KillerRed and *** suggests that the KillerRed protein based PDT m.ght provide a new approach for tum.r therapy accom.anied by altering tum.r m.tabolism.

关键词： Reactive oxygen species redox m.tabolism flavoprotein nicotinam.de adenine dinucleotide hydrogen

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Response of Artificial Grassland Carbon Stock to m.nagem.nt in m.untain Region of Southern Ningxia, China

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Chinese Geographical Science 2014年第4期24卷 436-443页

作者： TANG Long DANG Xiaohu LIU Guobin shaO Chuanke XUE sha School of Hum.n Settlem.nts and Civil Engineering Xi'an Jiaotong University College of Geology and Environm.nt Xi'an University of Science and Technology State Key Laboratory of Soil Erosion and Dryland Farm.ng on the Loess Plateau Institute of Soil and Water Conservation Chinese Academy of Sciences and Ministry of Water Resources

Grassland is a m.jor carbon sink in the terrestrial ecosystem. The dynam.cs of grassland carbon stock profoundly influence the global carbon cycle. In the published literatures so far, however, there are lim.ted studies on the long-term.dynam.cs and influential factors of grassland carbon stock, including soil organic carbon. In this study, spatial-tem.oral substitution m.thod was applied to explore the characteristics of m.dicago sativa L. （alfalfa） grassland biom.ss carbon and soil organic carbon density （SOCD） in a loess hilly region with different growing years and m.nagem.nt patterns. The results dem.nstrated that alfalfa was the m.no-dom.nant com.unity during the cutting period （viz. 0-10 year）. Com.unity succession began after the abandonm.nt of alfalfa grassland and then the im.ortant value of alfalfa in the com.unity declined. The artificial alfalfa com.unity abandoned for 30 years was replaced by the S. bungeana com.unity. Accordingly, the biom.ss carbon density of the clipped alfalfa showed a significant increase over the tim. during 0-10 year. During 0-30 year, the SOCD from.0-100 cm.of the soil layer of all 5 m.nagem.nt patterns increased over tim. with a range between 5.300 ± 0.981 kg/m. and 12.578 ± 0.863 kg/m.. The sloping croplands had the lowest SOCD at 5.300 ± 0.981 kg/m. which was quite different from.the abandoned grasslands growing for 30 years which exhibited the highest SOCD with 12.578 ± 0.863 kg/m.. The ecosystem.carbon density of the grassland clipped for 2 years increased 0.1 kg/m. com.ared with the sloping cropland, while that of the grassland clipped for 10 years substantially increased to 10.30 ± 1.26 kg/m.. m.reover, the ecosystem.carbon density for abandoned grassland becam. 12.62± 0.50 kg/m. at 30 years. The carbon density of the grassland undisturbed for l0 years was sim.lar to that of the sloping cropland and the grassland clipped for 2 years. Different m.nagem.nt patterns im.osed great different effects on the accum.lation of bio

关键词： artificial m.dicago sativa L. (alfalfa) grassland clipped grassland abandoned grassland carbon sink carbon density m.untain region southern Ningxia

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