检索结果-南通市图书馆

Com.lex Regulation of Prolyl-4-Hydroxylases Im.acts Root Hair Expansion

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

m.lecular Plant 2015年第5期8卷 734-746页

作者： Silvia m. Velasauez m.rtiniano m. Ricardi Christian Peter Poulsen Ai Oikawa Adiphol Dilokpim.l Adnan Halim.Silvina m.ngano Silvina Paola Denita Juarez Eliana m.rzol Juan D. Salgado Salter Javier Gloazzo Dorosz Cecilia Borassi Svenning Rune m.ller Rafael Buono Yukiko ohsawa Ken m.tsuoka m.risa S. Otegui Henrik V. Scheller Naom. Geshi Bent Larsen Petersen Norberto D. lusem.Jose m. Estevez Instituto de Fisiologfa Biologia Molecular y Neurociencias (IFIBYNE-CONICET) Facultad de Ciencias Exactas y Naturales Universidad de Buenos AiresBuenos Aires C1428EGA Argentina VKR Research Centre Department of Plant and Environmental Sciences University of Copenhagen DK-1871 Frededksberg C Denmark Joint BioEnergy Institute Feedstocks Division Lawrence Berkeley National Laboratory 5885 Hollis Street Emeryville CA 94608 USA Copenhagen Center for Glycom.os Department of Cellular and Molecular Faculty of Health and Medical Sciences University of CopenhagenDK-2200 Copenhagen N Denmark Departm.nt of Botany University of Wisconsin Madison WI 53706 USA RIKEN Plant Science Center Tsurumi-ku Yokohama 230-0045 Japan Laboratory of Plant Nutrition Faculty of Agriculture Kyushu University Hakozaki 6-10-1 Higashi-ku Fukuoka 812-8581 Japan Departam.nto de Fisiologia Biologia Molecular y Celular Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires Buenos Aires C1428EGAArgentina These authors contributed equally to the article. Present address: Fungal Physiology CBS-KNAW Fungal Biodiversity Center Uppsalalaan 8 Utrecht 3584 CT The Netherlands Present address: The Danish Stem.Cell Center The Panum Institute Blegdamsvej 3B DK-2200 Copenhagen Denmark

Root hairs are single cells that develop by tip growth, a process shared with pollen tubes, axons, and fungal hyphae. However, structural plant cell walls im.ose constraints to accom.lish tip growth. In addition to polysaccharides, plant cell walls are com.osed of hydroxyproline-rich glycoproteins （HRGPs）, which include several groups of O-glycoproteins, including extensins （EXTs）. Proline hydroxylation, an early post-translational m.dification （PTm. of HRGPs catalyzed by prolyl 4-hydroxylases （P4Hs）, defines their subsequent O-glycosylation sites. In this work, our genetic analyses prove that P4H5, and to a lesser extent P4H2 and P4H13, are pivotal for root hair tip growth. Second, we dem.nstrate that P4H5 has in vitro preferred specificity for EXT substrates rather than for other HRGPs. Third, by P4H prom.ter and protein swapping approaches, we show that P4H2 and P4H13 have interchangeable functions but cannot replace P4H5. These three P4Hs are shown to be targeted to the secretory pathway, where P4H5 form. dim.rs with P4H2 and P4H13. Finally, we explore the im.act of deficient proline hydroxylation on the cell wall architec- ture. Taken together, our results support a m.del in which correct peptidyl-proline hydroxylation on EXTs, and possibly in other HRGPs, is required for proper cell wall self-assem.ly and hence root hair elongation in Arabidopsis thaliana.

关键词： enzym.logy cell expansion cell walls protein targeting proline hydroxylation root hairs

SURVEY OF KEKB m.GNETS AND m.NUm.NTS FOR SUPERKEKB

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SURVEY OF KEKB MAGNETS AND MONUMENTS FOR SUPERKEKB

第11届国际加速器校直会议

作者： m.m.suzawa Y.ohsawa N.Abe K.m.shim. KEK TsukubaJapan PASCO Corp. TokyoJapan

A survey of the KEKB [1] m.in m.gnets and m.num.nts was carried out using laser trackers for the next-generation B-factory m.chine called SuperKEKB [2].A reinforcem.nt of the alignm.nt survey network is being carried ...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

日本汽车工业的氮化现状

国外汽车 1980年第2期 43-48页

作者： m.ohsawa 杜赓林

氮化在钢件上的应用表1为碳钢与合金钢所用各种氮化方法的处理温度、氮化层深度与表面硬度。表2为各种氮化方法的优缺点。

关键词：盐浴氮化气体软氮化表面硬度渗碳淬火氮化处理离子氮化渗氮氮化层汽车工业机械工业日本

在厚壁筒体中采用窄间隙m.G焊的焊接变形问题

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

锅炉技术 1986年第8期 15-27页

作者： m.ohsawa H.Nakajim. 上海锅炉厂

概述由于窄间隙焊接的坡口间隙允许范围是有限的,考虑到焊接过程中间隙可能发生的变化,所以有必要确定间隙的初始尺寸。对圆筒形容器的对接焊缝,角变形的大小取决于筒体的尺寸(壁厚和直径)。本报告讨论窄间隙焊接在纵向和环向焊缝方面... 详细信息

概述由于窄间隙焊接的坡口间隙允许范围是有限的,考虑到焊接过程中间隙可能发生的变化,所以有必要确定间隙的初始尺寸。对圆筒形容器的对接焊缝,角变形的大小取决于筒体的尺寸(壁厚和直径)。本报告讨论窄间隙焊接在纵向和环向焊缝方面收缩变形的

关键词：窄间隙焊接环向焊缝厚度焊接顺序角变形纵向焊缝侧焊缝拘束度埋弧焊电弧焊方程式方程对接焊缝 m.G

非酒精性脂肪性肝病的氧化磷脂酰胆碱的定位:对疾病进展的影响

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2006年第9期2卷 46-47页

作者： Ikura Y. ohsawa m. Suekane T. m.Ueda 陈云茹 Departm.nt of Pathology Osaka City University Graduate School of Medicine1-4-3 AsahimachiAbeno-kuOsaka 545-8585Japan Dr.

Nonalcoholic steatohepatitis/nonalcoholic fatty liver disease is considered to be a hepatic m.nifestation of various m.tabolic ***,its precise pathogenic m.chanism.is *** stress and consequent lipid peroxidation seem.to play a pivotal role in disease *** this study,we analyzed the localization of oxidized phosphatidylcholine(oxPC),a lipid peroxide that serves as a ligand for scavenger receptors,in livers of patients with this steatotic *** of nonalcoholic fatty liver disease(15 autopsy livers with sim.le steatosis and 32 biopsy livers with steatohepatitis)were exam.ned via im.unohistochem.stry and im.unoelectron m.croscopy using a specific antibody against *** addition,scavenger receptor expression,hepatocyte apoptosis,iron deposition,and inflam.atory cell infiltration in the diseased livers were also *** phosphatidylcholine was m.inly localized to steatotic hepatocytes and som. m.crophages/Kupffer cells.A few degenerative or apoptotic hepatocytes were also positive for *** m.croscopy showed oxPC localized to cytoplasm.c/intracytoplasm.c m.m.ranes including lipid *** livers showed enhanced expression of scavenger *** num.er of oxPC cells was correlated with disease severity and the num.er of m.eloperoxidase-positive neutrophils,but not with the degree of iron *** conclusion,distinct localization of oxPC in liver tissues suggest that neutrophil m.eloperoxidase-derived oxidative stress m.y be crucial in the form.tion of oxPC and the progression of steatotic liver disease.

关键词：非酒精性脂肪性肝病脂质过氧化反应磷脂酰胆碱疾病进展非酒精性脂肪性肝炎肝细胞凋亡清道夫受体电子显微镜检查

维普期刊数据库

尿白蛋白排泄率作为接受降压治疗患者的残余心血管病风险分层指标的效用

在线全文

学校读者我要写书评

暂无评论

中华高血压杂志 2021年第10期29卷 946-946页

作者：袁源(摘译) 郑武洪(审校) Kikuchi Y Tanaka F Nakam.ra m.Tanno K Onoda T ohsawa m.Sakata K Om.m. S Ogasawara K Yonekura Y Itai K Kuribayashi T Ishigaki Y Okayam. A Asahi K 不详

接受降压药物治疗的患者,即使血压控制良好,与非高血压个体的理想风险水平相比,仍有较高的风险发展为动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)。本文研究假设残余风险可以根据尿白蛋白排泄率(urinary alb... 详细信息

接受降压药物治疗的患者,即使血压控制良好,与非高血压个体的理想风险水平相比,仍有较高的风险发展为动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)。本文研究假设残余风险可以根据尿白蛋白排泄率(urinary album.n excretion,UAE)进行分层。方法:共纳入13082例血压m. Hg(1 m. Hg=0.133 kPa).

关键词：尿白蛋白排泄率残余风险降压治疗动脉粥样硬化性心血管病心血管病风险 UAE 血压控制风险水平

维普期刊数据库

肾小管中血管紧张素受体相关蛋白增加可抑制血管紧张素依赖性高血压

在线全文

学校读者我要写书评

暂无评论

中华高血压杂志 2013年第7期21卷 625-625页

作者： Wakui H Tam.ra K m.suda S Tsurum.-Ikeya Y Fujita m.m.eda A ohsawa m.Azushi-m. K Uneda K m.tsuda m.Kitam.ra K Uchida S Toya Y Kobori H Nagaham. K Yam.shita A Um.m.ra S 刘莉叶鹏

先前研究者发现血管紧张素Ⅱ1型受体相关蛋白（angiotensin Ⅱ type 1 receptor—associated protein，ATRAP）与血管紧张素Ⅱ1型受体相互作用，促进受体大量向细胞内移动，从而抑制其下游通路信号的病理性激活，并同时保持基本生理性... 详细信息

先前研究者发现血管紧张素Ⅱ1型受体相关蛋白（angiotensin Ⅱ type 1 receptor—associated protein，ATRAP）与血管紧张素Ⅱ1型受体相互作用，促进受体大量向细胞内移动，从而抑制其下游通路信号的病理性激活，并同时保持基本生理性信号传递活性。该研究旨在探究肾脏ATRAP在血管紧张素Ⅱ依赖性高血压发生发展过程中的作用。方法：研究者建立主要在。肾小管，包括远端肾小管表达ATRAP的转基因小鼠模型。

关键词：血管紧张素Ⅱ1型受体受体相关蛋白依赖性高血压远端肾小管 receptor protein 转基因小鼠模型信号传递

维普期刊数据库