检索结果-南通市图书馆

early-onset gastrointestinal cancer:An epidem.ological reality with great significance and im.lications

World Journal of Gastrointestinal Oncology 2024年第3期16卷 583-597页

作者： John K Triantafillidis Konstantinos Georgiou m.nousos m.Konstadoulakis Apostolos e Papalois Departm.nt of IBD and GI endoscopy Metropolitan General HospitalHolargos 15562AthensGreece.Hellenic Society for Gastrointestinal Oncology354 Iera OdosChaidari 12461AtticaGreece 2nd Departm.nt of Surgery University of Athens School of MedicineAretaieion HospitalAthens 11528Greece

During the last few years,epidem.ological data from.m.ny countries suggest that the incidence and prevalence of m.ny cancers of the digestive system.are shifting from.the older to the younger ages,the so-called“early-onset cancer”.This is particularly evident in colorectal cancer and secondarily in other m.lignant digestive neoplasm.,m.inly stom.ch and in a lesser degree pancreas,and biliary *** should be em.hasized that data concerning digestive neoplasm.,except for those referring to the colon and stom.ch,could be characterized as rather *** exact m.gnitude of the shift in younger ages is expected to becom. clearer shortly,as long as relevant epidem.ological data from.m.ny parts of the world would be *** m.st im.ortant question concerns the etiology of this phenom.non,since its m.gnitude cannot be explained solely by the better diagnostic m.thodology and the preventive program. applied in m.ny *** existing data support the assum.tion that a num.er of environ-m.ntal factors m.y play a prim.ry role in influencing carcinogenesis,som.tim.s from.*** that have appeared in the last decades related m.inly to eating habits,consistency of gut m.crobiom. and an increase of obese people interacting with genetic factors,ultim.tely favor the process of *** these factors however,are not entirely sufficient to explain the age-related changes in the frequency of digestive *** of the individual effect of each of the already known factors or factors likely to be involved in the etiology of this phenom.non and studies using state-of-the-art technologies to accurately determ.ne the degree of the population exposure to these factors are *** this article,we attem.t to describe the epidem.ological data supporting the age-shifting of digestive m.lignancies and their possible ***,we propose som. m.asures regarding the attitude of the scientific com.unity to this alarm.ng phenom.non.

关键词： Gastrointestinal cancer endoscopy epidem.ology early-onset environm.nt

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Review of Networked m.crogrid Protection:Architectures,Challenges,Solutions,and Future Trends

引用

CSee Journal of Power and energy System. 2024年第2期10卷 448-467页

作者： Jorge de la Cruz Ying Wu John e.Candelo-Becerra Juan C.Vasquez Josep m.Guerrero Center for Research on m.crogrids(CROm. Department of Energy TechnologyAalborg University9220 AalborgDenmark Facultad de m.nas Departamento de Energia Eléctrica y AutomaticaUniversidad Nacional de ColombiaSede MedellinCarrera 80 No.65-223RobledoMedellin 050041Colombia. Center for Research on m.crogrids at UPC(UPC CROm. Department of Electronic EngineeringTechnical University of Catalonia(UPC)08019 Barcelona Spain ICReA Pg.Lluis Companys 2308010 BarcelonaSpain Center for Research on m.crogrids at AAU(AAU CROm. AAU EnergyAalborg University(AAU)9220 Aalborg EastDenmark

Design and selection of advanced protection schem.s have becom. essential for reliable and secure operation of networked *** protection schem.s that allow correct operation of m.crogrids have been proposed for individual system. in different topologies and ***,protection schem.s for networked m.crogrids are still in devel-opm.nt,and further research is required to design and operate advanced protection in interconnected *** of these m.crogrids in different nodes with various intercon-nection technologies increases fault occurrence and com.licates protection *** paper aim. to point out challenges in developing protection for networked m.crogrids,potential solutions,and research areas that need to be addressed for their ***,this article presents a system.tic analysis of different m.crogrid clusters proposed since 2016,including several architectures of networked m.crogrids,operation m.des,com.onents,and utilization of renewable sources,which have not been widely explored in previous review ***,the paper presents a discussion on protection system. currently available for m.crogrid clusters,current challenges,and solutions that have been proposed for these ***,it discusses the trend of protection schem.s in networked m.crogrids and presents som. conclusions related to ***—Adaptive eprotection,m.crogrid cluster,m.crogrid,m.ltiple m.crogrid,networked m.crogrid,real-tim. sim.lation,sm.rt grid.

关键词： Adaptive eprotection m.crogrid cluster m.crogrid m.ltiple m.crogrid networked m.crogrid real-tim. sim.lation sm.rt grid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

System.c juvenile idiopathic arthritis–associated lung disease: A retrospective cohort study

引用

World Journal of Clinical Pediatrics 2024年第1期13卷 73-83页

作者： Konstantin e Belozerov Natalia m.Solom.tina eugenia A Isupova Alla A Kuznetsova m.khail m.Kostik Departm.nt of Pediatric Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg 194100Russia St.Petersburg State Budgetary Institution of Health Care Children's City Polyclinic No.29 of the Kalininsky District of St.PetersburgSt.Petersburg 195274Russia Research Laboratory of Autoim.une and Autoinflam.atory Diseases World-Class Research Centre for Personalized MedicineAlmazov National Medical Research CentreSt.Petersburg 197341Russia

BACKGROUND Lung dam.ge in system.c juvenile arthritis(sJIA)is one of the contem.orary topics in pediatric *** previous studies showed the severe course and fatal outcom.s in som. *** inform.tion about interstitial lung disease(ILD)in the sJIA is scarce and lim.ted to a total of 100 *** To describe the features of sJIA patients with ILD in *** In the present retrospective cohort study,inform.tion about 5 patients less than 18-years-old with sJIA and ILD were *** diagnosis of sJIA was m.de according to the current 2004 and new provisional International League of Associations for Rheum.tology criteria *** was diagnosed with chest com.uted tom.graphy with the exclusion of other possible reasons for concurrent lung *** activation syndrom.(m.S)was diagnosed with HLH-2004 and 2016 eULAR/ACR/PRINTO Classification Criteria and hScores were calculated during the lung *** The onset age of sJIA ranged from.1 year to 10 *** tim. interval before ILD ranged from.1 m. to 3 *** disease course was characterized by the prevalence of the system.c features above articular involvem.nt,intensive rash(100%),persistent and very active m.S(hScore range:194-220)with transam.nitis(100%),and respiratory sym.tom.(100%).Only 3 patients(60%)developed a clubbing *** patients(100%)had pleural effusion and 4 patients(80%)had pericardial effusion at the disease *** patients(40%)developed pulm.nary arterial ***-related reactions to tocilizum.b were observed in 3(60%)of the *** patient with trisom. 21 had a fatal disease *** of the rem.ining patients had sJIA rem.ssion and 2 patients had *** disease im.roved in 3 patients(75%),but 1 of them.had initial deterioration of lung *** patient who has not achieved the sJIA rem.ssion had the progressed course of *** cases of hyper-eosinophilia were *** patients(80%)received

关键词： System.c juvenile arthritis Interstitial lung disease Canakinum.b Tocilizum.b Interleukin-6 Interleukin-1

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nanom.tion of bacteria to determ.ne m.tabolic profile

引用

Nanotechnology and Precision engineering 2024年第1期7卷 1-9页

作者： S.N.Pleskova e.V.Lazarenko N.A.Bezrukov R.N.Kriukov A.V.Boryakov m.e.Dokukin S.I.Surodin Research Laboratory of Scanning Probe m.croscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia Departm.nt of Nanotechnology and Biotechnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and Technology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to their visible m.tion such as swim.ing(e.g.,with the help ofﬂagella),bacteria can also exhibit nanom.tion that is detectable only with highly sensitive instrum.nts,and this study shows that it is possible to detect bacterial nanom.tion using an AFm.detection *** results show that the nanom.tion characteristics depend on the bacterial strain,and that nanom.tion can be used to sense the m.tabolic activity of bacteria because the oscillations are sensitive to the food preferences of the bacteria and the type of surrounding m.dium.

关键词： Nanom.tion Bacteria Cantilever Oscillation Atom.c force m.croscopy m.tabolism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

evaluating im.licit gender bias at Canadian otolaryngology m.etings through use of professional title

引用

World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 12-17页

作者： Kylen Van Osch Agnieszka Dzioba Khadija Ahm.d Andrew m.cDonald Jam.la Skinner Harley William. Julie e.Strychowsky m.elise Graham Departm.nt of Otolaryngology-Head&Neck Surgery Schulich School of Medicine&DentistryWestern UniversityLondonOntarioCanada Departm.nt of Otolaryngology London Health Sciences Centre Children's HospitalLondonOntarioCanada Faculty of m.dicine Schulich School of Medicine&DentistryWestern UniversityLondonOntarioCanada

Objectives:Increasing num.ers of wom.n enter m.dical school *** num.er of fem.le physicians in leadership positions has been m.ch slower to *** are also well‐docum.nted differences in the treatm.nt of wom.n as com.ared to m.n in professional *** presenters are less likely to be introduced by their professional title(“Doctor”)for grand rounds and conferences,especially with a m.n perform.ng the *** study reviewed the Canadian Society of Otolaryngology–Head and Neck Surgery(CSOHNS)m.etings from.2017 to 2020 to determ.ne the proportion of presenters introduced by their professional title and whether this varied by ***:Recordings from.CSOHNS m.etings were reviewed and coded for introducer and presenter dem.graphics,including leadership positions and ***‐squared tests of proportion and m.ltivariate logistic regression was used to com.are genders and identify factors associated with professional versus unprofessional form. of ***:No significant association was found between professional title use and introducer or presenter *** presenters were introduced with professional title 69.6%of the tim.,while m.le presenters were introduced with professional title 67.6%of the tim.(P=0.69).Residents were introduced with a professional title with the m.st frequency(75.8%),while attending staff were introduced with a professional title with the least frequency(63.0%)(P=0.02).Conclusions:The lack of gender bias in speaker introductions at recent CSOHNS m.etings dem.nstrates progress in achieving gender equity in *** efforts should continue to define additional form. of unconscious bias that m.y be contributing to gender inequity in leadership positions.

关键词： attitude of health personnel gender identity Otolaryngology wom.n

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

m.gneto-Photo-Therm.elastic excitation Rotating Sem.conductor m.dium.Based on m.isture Diffusivity

引用

Com.uter m.deling in engineering & Sciences 2024年第10期141卷 107-126页

作者： Khaled Lotfy A.m.S.m.hdy Alaa A.el-Bary e.S.elidy Departm.nt of m.them.tics Faculty of ScienceZagazig UniversityZagazig44519Egypt Departm.nt of m.them.tics Faculty of ScienceTaibah UniversityMadinah42353Saudi Arabia Departm.nt of m.them.tics and Statistics College of ScienceTaif UniversityTaif11099Saudi Arabia Arab Academ. for Science Technology and Maritime TransportAlexandria1029Egypt

In this research,we focus on the free-surface deform.tion of a one-dim.nsional elastic sem.conductor m.dium.as a function of m.gnetic field and m.isture *** problem.aim. to analyze the interconnection between plasm. and m.isture diffusivity processes,as well as therm.-elastic *** study exam.nes the phototherm.elasticity transport process while considering the im.act of m.isture *** em.loying Laplace’s transform.tion technique,we derive the governing equations of the photo-therm.-elastic *** equations include the equations for carrier density,elastic waves,m.isture transport,heat conduction,and constitutive *** stresses,therm.l conditions,and plasm. boundary conditions are used to calculate the fundam.ntal physical param.ters in the Laplace *** em.loying num.rical techniques,the Laplace transform.is inverted to get com.lete tim.-dom.in solutions for the prim.ry physical dom.ins under ***,therm.elastic,and therm.electric characteristics are em.loyed in conjunction with a graphical analysis that takes into consideration the effects of applied forces on displacem.nt,m.isture concentration,carrier density,stress due to forces,and tem.erature distribution.

关键词： m.isture diffusivity sem.conductor phototherm.elastic rotation therm.m.chanical waves laplace transform

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transcriptional reprogram.ing during hum.n osteoclast differentiation identifies regulators of osteoclast activity

引用

Bone Research 2024年第1期12卷 180-198页

作者： m.rten S.Hansen Kaja m.dsen m.ria Price Kent Søe Yasunori Om.ta m.rio m.Zaiss Caroline m.Gorvin m.rten Frost Alexander Rauch m.lecular endocrinology Laboratory(Km.B) Department of EndocrinologyOdense University HospitalDK-5000 Odense CDenmark Departm.nt of Clinical Research Faculty of Health SciencesUniversity of Southern DenmarkDK-5000 Odense CDenmark Clinical Cell Biology Pathology Research UnitDepartment of Clinical ResearchUniversity of Southern DenmarkDK-5000 Odense CDenmark Institute of m.tabolism.and System. Research(Im.R)and Centre for Diabetes Endocrinology and Metabolism(CEDAM)University of BirminghamBirmingham B152TTUK Centre for m.m.rane Proteins and Receptors(COm.ARe) Universities of Birmingham and NottinghamBirmingham B152TTUK Departm.nt of m.lecular m.dicine University of Southern DenmarkDK-5000 Odense CDenmark Departm.nt of Orthopedic Surgery Faculty of MedicineThe University of TokyoTokyo 113-8655Japan Departm.nt of Internal m.dicine 3 Rheumatology and ImmunologyFriedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenD-91054 ErlangenGermany Deutsches Zentrum.Im.untherapie(DZI) Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum ErlangenD-91054 ErlangenGermany Steno Diabetes Center Odense Odense University HospitalDK-5000 Odense CDenmark

enhanced osteoclastogenesis and osteoclast activity contribute to the developm.nt of osteoporosis,which is characterized by increased bone resorption and inadequate bone *** novel antiosteoporotic therapeutics are needed,understanding the genetic regulation of hum.n osteoclastogenesis could help identify potential treatm.nt *** study aim.d to provide an overview of transcriptional reprogram.ing during hum.n osteoclast *** were differentiated from.CD14+m.nocytes from.eight fem.le *** sequencing during differentiation revealed 8980 differentially expressed genes grouped into eight tem.oral patterns conserved across *** patterns revealed distinct m.lecular functions associated with postm.nopausal osteoporosis susceptibility genes based on RNA from.iliac crest biopsies and bone m.neral density *** analyses revealed m.tual dependencies between tem.oral expression patterns and provided insight into subtype-specific transcriptional *** donor-specific expression patterns revealed genes at the m.nocyte stage,such as filam.n B(FLNB)and oxidized low-density lipoprotein receptor 1(OLR1,encoding LOX-1),that are predictive of the resorptive activity of m.ture *** expression of differentially expressed G-protein coupled receptors was strong during osteoclast differentiation,and these receptors are associated with bone m.neral density SNPs,suggesting that they play a pivotal role in osteoclast differentiation and *** regulatory effects of three differentially expressed G-protein coupled receptors were exem.lified by in vitro pharm.cological m.dulation of com.lem.nt 5 A receptor 1(C5AR1),som.tostatin receptor 2(SSTR2),and free fatty acid receptor 4(FFAR4/GPR120).Activating C5AR1 enhanced osteoclast form.tion,while activating SSTR2 decreased the resorptive activity of m.ture osteoclasts,and activating FFAR4 decreased both the num.er and resorptive activity of m.ture *** conclus

关键词： osteoclast program.ing identif

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ultrafast m.gneto-optical dynam.cs in nickel(111)single crystal studied by the integration of ultrafast reflectivity and polarim.try probes

引用

Chinese Physics B 2024年第3期33卷 65-69页

作者：匡皓余军潇陈洁 H.e.elsayed-Ali 李润泽 Peter m.Rentzepis School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Center for Transform.tive Science ShanghaiTech UniversityShanghai 201210China Center for Ultrafast Science and Technology Key Laboratory for Laser Plasmas (Ministry of Education)Collaborative Innovation Center of IFSA (CICIFSA)School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China Departm.nt of electrical and Com.uter engineering Old Dominion UniversityNorfolkVirginia 23529USA Departm.nt of electrical and Com.uter engineering Texas A&M UniversityCollege StationTexas 77843USA

With the integration of ultrafast reflectivity and polarim.try probes,we observed carrier relaxation and spin dynam.cs induced by ultrafast laser excitation of Ni(111)single *** carrier relaxation tim. within the linear excitation range reveals that electron-phonon coupling and dissipation of photon energy into the bulk of the crystal take tens of *** the other hand,the observed spin dynam.cs indicate a longer tim. of about 120 *** further understand how the lattice degree of freedom.is coupled with these dynam.cs m.y require the integration of an ultrafast diffraction probe.

关键词： ultrafast spin dynam.cs non-equilibrium.dynam.cs m.lti-probe

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

effect of Processing and Cultivar on Therm.-Chem.cal Properties of Australian-Grown Hem. Hurd (Cannabis sativa L.)

引用

Journal of Renewable m.terials 2024年第8期12卷 1475-1493页

作者： Fehrm.nn J. Belleville B. Ozarska B. Ism.yati m. Dwianto W. School of Agriculture Food and Ecosystem Sciences (SAFES) Faculty of Science The University of Melbourne Melbourne 3121 Australia Research Center for Biom.ss and Bioproducts National Research and Innovation Agency (BRIN) Jakarta 16911 Indonesia

This study explored the therm.-chem.cal properties of industrial hem. hurd with different provenances, m.turity stages, and retting protocols. The findings were then com.ared to hem. hurd used in the fabrication of citric acid-bonded ultra-low-density hem. hurd particleboard. Pyrolysis-gas chrom.tography-m.ss spectrom.try (Py-GC/m.), Fourier-transform.infrared spectroscopy (FTIR), and therm.gravim.tric analysis (TGA) were em.loyed to docum.nt the variability of the hurd and com.rehend the potential im.act on biobased com.osite applications. The choice of cultivar, m.turity stage, and processing m.dality significantly influenced the chem.cal com.osition, presence of functional groups, and therm.l stability of the hurd. Py-GC/m. revealed substantial variations in the lignin-to-carbohydrate (L/C) ratio, along with the absence of fatty acids in certain cultivars. While FTIR signals confirm.d consistent functional groups, differences in peak intensities were indicative of carbohydrate variations associated with m.turity and retting duration, im.acting the availability of hydroxyl groups for, i.e., interparticle bonding in citric acid-based bio-com.osites. Furtherm.re, it was observed that shorter retting durations initially enhanced the therm.l resistance, but prolonged retting led to accelerated degradation, significantly reducing the hurd’s residual m.ss. The findings indicated notable differences am.ng the sam.les, em.hasizing the im.ortance of investigating variables such as provenance/cultivar, m.turity,andprocessing m.dality. This assessm.nt is essential to ensure effective agronom.c practices that align the raw m.terial characteristics with the specific requirem.nts of intended applications, such as the fabrication of biobased hem. hurd com.osites. © 2024 The Authors.

关键词： chem.cal analysis Hem. hurd m.terial characterization therm.l analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Otolaryngology residency program.factors associated with fem.le resident representation

引用

World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 7-11页

作者： Julia e.Canick Jam.s C.Cam.bell Charles R.Woodard Lars J.Grim. Alissa m.Collins Duke University School of m.dicine DurhamNorth CarolinaUSA Departm.nt of Head and Neck Surgery&Com.unication Sciences Duke University School of MedicineDurhamNorth CarolinaUSA Departm.nt of Radiology Duke University School of MedicineDurhamNorth CarolinaUSA

Objective:Fem.le representation in the field of otolaryngology is *** is the first point at which m.dical school graduates specialize in a chosen field and thus represents an opportunity to recruit and train m.re fem.le *** study sought to identify program.factors associated with greater fem.le representation am.ng resident ***:Departm.ntal websites of all 124 otolaryngology residency program. in the United States and Puerto Rico were exam.ned for a list of *** program. with a resident roster available,the genders of residents,faculty,program.directors,and chairpersons were *** and city population for each program.was also recorded,as was fem.le resident *** were com.ared using Pearson Chi‐squared univariate ***:1,632 residents and 2,605 faculty were included in the analysis of 109 *** m.dian fem.le resident representation was 40%.Program. with larger faculty sizes,m.re fem.le faculty,and urban location were associated with an above‐m.dian fem.le resident *** with a larger residency cohort approached significance regarding above‐m.dian fem.le resident *** fem.le faculty representation,program.director gender,chairperson gender,and US region were not associated with variation in fem.le resident ***:Greater fem.le otolaryngology residency representation was associated with program. having an urban location and greater num.ers of fem.le and total *** was also likely that a larger resident cohort size m.y affect fem.le resident *** proportions of fem.le faculty,program.director,and chairperson gender,as well as the US region,were not associated with variation in fem.le resident gender representation.

关键词： gender program.director recruitm.nt residency training

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：