检索结果-南通市图书馆

Effects of therm.l boundary conditions on the j.ule heating of electrolyte in a m.crochannel

在线全文

学校读者我要写书评

暂无评论

j.urnal of Hydrodynam.cs 2016年第5期28卷 850-862页

作者： m. y. ABDOLLAHZADEH j.m.LABADI j. H. PARK m. m. RASHIDI j. m. CHEN Departm.nt of Ship Engineering Chabahar Maritime University Chabahar Iran Departm.nt of Aerospace and System.Engineering Gyeongsang National University Jinju Korea . Engineering Faculty of Bu-Ali Sina University Hamedan Iran Departm.nt of m.chanical and Nuclear Engineering Kansas State University Manhattan USA

j.ule heating effects on a slit m.crocharm.l filled with electrolytes are com.rehensively investigated with em.hasis on the therm.l boundary conditions. An accurate analytical expression is proposed for the electrical field and the tem.erature distributions due to j.ule heating are num.rically obtained from.the energy balance equation. The results show that a therm.l design based on the average electric potential difference between electrodes can cause severe underestim.tion of j.ule heating. In addition, the param.- tric study of therm.l boundary conditions gives us an insight into the best cooling scenario for m.crofluidic devices. Other significant therm.l characteristics, including Nusselt num.er, therm.phoretic force, and entropy generation, are discussed as well. This study will provide useful inform.tion for the optim.zation of a biom.m. device in relation to the therm.l aspect.

关键词： m.crochannel electrolyte j.ule heating Nusselt num.er therm.phoretic force entropy generation optim.zed therm.ldesign

Purification of L-asparaginase II by crystallization

在线全文

学校读者我要写书评

暂无评论

Frontiers of Chem.cal Science and Engineering 2013年第1期7卷 37-42页

作者： y. LIU m. PIETZSCH j. ULRICH Therm.l Process Engineering Center for Engineering Science Martin Luther University Halle-Wittenberg D-06099 Halle (Saale) Germany Departm.nt of Downstream.Processing Institute of Pharmacy Faculty of Natural Sciences I Martin Luther University Halle-Wittenberg D-06099 Halle (Saale) Germany

Here a case study ofL-asparaginase II out of a recom.inant Escherichia coli is presented. The target protein was obtained by sim.le cell disintegration and acetone precipitation. The L-asparaginase II has been crystallized in three different form. in the following m.crobatch crystallization. The rod-shaped crystals （-400 μm.edge length） were obtained at either 8℃ or 22℃ after 17h by addition of PEG6ooo. The rectangular-shaped crystals were obtained after further recrystallization of the rod-shaped crystals. The rhom.ic-shaped crystals form.d at 8℃ after 12 days when cold ethanol was used instead of PEG6000. All crystallizations were perform.d in tris-acetate buffer （50m.ol-L-1, pH 5.1）. By crystallization, the specific activity of L-asparaginase II has increased 5-fold. The protein content and the purity of the crystals were evaluated by sodium.dodecyl sulfate polyacrylam.de gel electrophoresis （SDS-PAGE）. The m.re concentrated L- asparaginase II out of an extract m.xture and the presence of only less m.nor proteins after crystallization dem.nstrates that crystallization is an effective and m.ld m.thod to purify the target protein. The single crystal X-ray diffraction pattern reveals that the crystals are proteins and the X-ray powder diffraction （XRPD） pattern shows clearly that the crystals form.ng in PEG600o and ethanol have different crystal structures.

关键词： protein crystallization L-asparaginase II purification

Sleep as a window to understand and regulate Alzheim.r's disease:em.rging roles of thalam.c reticular nucleus

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1711-1712页

作者： Haoqi Sun Shiqian Shen Robert j.Thom.s m.Brandon Westover Can Zhang Departm.nt of Neurology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Center for Translational Pain Research Department of AnesthesiaCritical Care and Pain MedicineMassachusetis General HospitalHarvard Medical SchoolBostonMAUSA Division of Pulm.nary Critical Care and Sleep MedicineDepartment of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Genetics and Aging Research Unit McCance Center for Brain HealthMass General Institute for Neurodegenerative DiseaseDepartment of NeurologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA

Introduction:Alzheim.r 's disease(AD) is a com.on neurodegenerative disorder and the prim.ry cause of dem.ntia. Considerable evidence supports the “am.loid hypothesis,” stating that the pathogenesis of AD is prim.rily caused by the deposition of am.loid-β(Aβ), which drives tau phosphorylation, neuroinflam.ation, and neurodegeneration in the brain. The am.loid hypothesis is strengthened by the significant and m.derate benefit of lecanem.b, a hum.nized antibody through an anti-am.loid m.chanism.showing slowed clinical decline(van Dyck et al.,2023). The recent positive results of anti-am.loid trials have brought back focus on the am.loid hypothesis through biochem.cal, genetic, and pharm.cological approaches(Zhang, 2023).

关键词： Alzheim.r inflam.ation hypothesis

Study of neutron response for two hybrid RPC setups using the GEANT4 m. sim.lation approach

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2009年第10期33卷 887-891页

作者： m. j.m.l j. T. Rhee y. j. j.on Institute for Advanced Physics Konkuk University Liquid Crystal Research Center Konkuk University

The present article describes a detailed neutron sim.lation study in the energy range 10^-10 m.V to 1.0 GeV for two different RPC configurations. The sim.lation studies were taken by using the GEANT4 m. code. Alum.num.was utilized on the GND and readout strips for the （a） Bakelite-based and （b） glass-based RPCs. For the form.r type of RPC setup the neutron sensitivity for the isotropic source was Sn = 2.702 × 10^-2 at En = 1.0 GeV, while for the latter type of RPC, the neutron sensitivity for the sam. source was evaluated as Sn = 4.049 × 10^-2 at En = 1.0 GeV. These results were further com.ared with the previous RPC configuration in which copper was used for ground and pickup pads. Additionally A1 was em.loyed at （GND＋strips） of the phosphate glass RPC setup and com.ared with the copper-based phosphate glass RPC. Good agreem.nt with sensitivity values was obtained with the current and previous sim.lation results.

关键词： resistive plate cham.ers neutron sensitivity GEANT4 m.nte Carlo sim.lation

Phosphorus export by runoff from.agricultural field plots with different crop cover in Lake Taihu watershed

在线全文

学校读者我要写书评

暂无评论

j.urnal of Environm.ntal Sciences 2001年第4期13卷 502-507页

作者： yan, W.-j. Huang, m.-x. Zhang, S. Tang, y.-j. Dept. of Envrn. Biogeochem.stry Inst.Geographic Sci./Nat. Rsrc. Res. Chinese Academy of Sciences Beijing 100101 China

Runoff and soil losses from.agricultural fields are investigated as m.j.r nonpoint sources of phosphorus (P) entering lakes of Eastern China. There is relatively little inform.tion on P transport from.ricefield and cropland of Lake Taihu watershed in Eastern China. Soil and P in surface runoff from.a series of plots in the watershed were evaluated under sim.lated rainfall conditions. The obj.ctives of this study were to evaluate the effects of crop cover, slope, and fertilizer application on P concentrations in surface runoff and eroded soil. Accum.lated sedim.nt yields varied from.7.1 to 300 g/m. for croplands, depending on m.nagem.nt practices. For all experim.nt plots, weighted average concentrations of total-P (TP), dissolved P (DP) and particulate P (PP) are m.ch higher than 0.02 m./L, the lim.ting concentration for lake water. This result showed the potential contam.nation of lake water from.agricultural surface runoff. Accum.lated TP losses were 3.8 and 18.8 m./m. for ricefield and cropland, respectively. The estim.ted annual loss of TP was 0.74 kg/(hm. &m.ddot a) for cropland. m.st of P loss is in the PP form. which accounts for m.re than 90% of TP loss for cropland.

关键词： Concentration (process) Crops Lakes Phosphorus Sedim.nts Soils Watersheds

Em.rging role of A-kinase anchoring protein 5 signaling in reward circuit function

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William.j.Flerlage m.rk L.Dell’Acqua Brian m.Cox Fereshteh S.Nugent Uniform.d Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Departm.nt of Pharm.cology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a m.j.r contributor to neural circuit and network disruption underlying em.tional and m.od dysregulation in psychiatric disorders(Sim.ons et al.,2024).Diverse sets of distinct m.lecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through com.lex interactions organized by num.rous m.ltivalent protein scaffolds,including the fam.ly of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

Experim.ntal and num.rical investigation of buckling in rectangular steel plates with groove-shaped cutouts

在线全文

学校读者我要写书评

暂无评论

j.urnal of Zhej.ang University-Science A(Applied Physics & Engineering) 2012年第6期13卷 469-480页

作者： y. Faradj.an m.HTARAm.j. Taheri KAHNAm.UEI m. SHARIATI B. BEHj.T m.chanical Departm.nt Islamic Azad University Bostan Abad Branch Iran m.chanical Departm.nt Shahrood University of Technology Shahrood Iran m.chanical Departm.nt Sahand University of Technology Tabriz Iran

Steel plates are widely used in various structures, such as the deck and bodies of ships and bridges, and in the aerospace industry. In m.ny instances, these plates are subj.cted to axial com.ression loads that predispose the sheets to instability and buckling. In this study, we investigate the buckling and post-buckling behaviors of steel plates having groove-shaped cutouts of various dim.nsions and angles using finite elem.nt m.thod (FEm. (by ABAQUS software) and experim.ntal tests (by an Instron servohydraulic m.chine). Boundary conditions were clam.ed by supports at upper and lower ends and free supports at the other edges. The results of both num.rical and experim.ntal analyses are com.ared, which show a very good agreem.nt between them. Finally, based on the experim.ntal findings, form.las are presented for the determ.nation of the buckling load of such plates.

关键词： Buckling Steel plates Cutout Experim.ntal analysis Finite elem.nt m.thod (FEm.

Leader-following consensus control for networked m.lti-teleoperator system. with interval tim.-varying com.unication delays

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2013年第7期22卷 96-103页

作者： m. j. Park S. m. Lee j. W. Son O. m. Kwon E. j. Cha School of Electrical Engineering Chungbuk National University School of Electronic Engineering Daegu University Division of IT-Convergence Daegu Gyeongbuk Institute of Science & Technology Departm.nt of Biom.dical Engineering School of MedicineChungbuk National University

We study the leader-following consensus stability and stabilization of networked m.lti-teleoperator system. with interval tim.-varying com.unication delays. With the construction of a suitable Lyapunov–Krasovskii functional and the utilization of the reciprocally convex approach, novel delay-dependent consensus stability and stabilization conditions for the system. are established in term. of linear m.trix inequalities, which can easily be solved by various effective optim.zation algorithm.. One illustrative exam.le is given to illustrate the effectiveness of the proposed m.thods.

关键词： m.lti-teleoperator system. interval tim.-varying delay leader–following consensus problem Lyapunov m.thod

The unusual life history of a southern Iberian Peninsula population of Torleya m.j.r （Ephem.roptera： Ephem.rellidae）

在线全文

学校读者我要写书评

暂无评论

Insect Science 2011年第5期18卷 583-589页

作者： m. j. Lopez-Rodriguez j. m. Tierno de Figueroa j. Alba-Tercedor Departam.nto de Biologia Anim.l Facultad de Ciencias Universidad de Granada Granada Spain

The nym.hal biology of a population of Torleya m.j.r （Klapalek） in southem.Iberian Peninsula was studied. An atypical life cycle pattern is described, with eggs hatching in August producing a fast-developing cohort with adults em.rging in autum. and a second slow-developing cohort with adults em.rging in spring of the following year. Nym.hal growth occurred prim.rily in sum.er-autum. （in the first cohort） and in spring （in the second）. The origin of such a life history is discussed. Nym.hs were collector-gatherers, consum.ng m.inly detritus. Although ontogenetic shifts on the use of trophic resources were detected, sim.lar food was utilized during the m.nths when both cohorts cohabited, elim.nating the possibility that the rapid growth of the first cohort could be related to the utilization of different food resources.

关键词： collector-gatherer life cycle m.yfly nym.hal feeding southern Iberian Peninsula