检索结果-南通市图书馆

Com.ination tre.tm.nt of inflam.atory bowe. dise.se.Pre.e.t status and future.pe.spe.tive.

World Journal of Gastroe.te.ology 2024年第15期30卷 2068-2080页

作者： John K Triantafillidis Constantinos G Zografos m.nousos m.Konstadoulakis Apostolos e.Papalois Inflam.atory Bowe. Dise.se.Unit "Metropolitan General"HospitalHolargos 15562AtticaGreece He.le.ic Socie.y for Gastrointe.tinal Oncology 354 Iera OdosChaidari 12461AtticaGreece The.2^(nd)De.artm.nt of Surge.y University of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece Unit of Surgical Re.e.rch and Training The 2^(nd)Department of SurgeryUniversity of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece

The.tre.tm.nt of patie.ts with inflam.atory bowe. dise.se.IBD),e.pe.ially those.with se.e.e.or re.ractory dise.se.re.re.e.ts an im.ortant challe.ge.for the.clinical *** se.m. to be.no e.agge.ation to say that in the.e.patie.ts,not only the.scie.tific background of the.gastroe.te.ologist is te.te.,but also the.abundance.of“gifts”that he.should posse.s(insight,intuition,de.e.m.ination,ability to take.initiative.e.c.)for the.succe.sful outcom. of the.*** daily clinical practice.de.e.ding on the.se.e.ity of the.attack,IBD is tre.te. with one.or a com.ination of two or m.re.pharm.ce.tical *** com.in-ations include.not only the.first-line.drugs(e.g.,m.salazine.corticoste.oids,antibiotics,e.c)but also se.ond-and third-line.drugs(im.unosuppre.sants and biologic age.ts).It is a fact that de.pite.the.significant the.ape.tic advance. the.e.is still a significant pe.ce.tage.of patie.ts who do not satisfactorily re.pond to the.tre.tm.nt ***,a part of the.e.patie.ts are.going to *** re.e.t ye.rs,se.e.al sm.ll-size.clinical studie.,re.ie.s,and case.re.orts have.be.n publishe. com.ining not only biological age.ts with othe. drugs(e.g.,im.unosuppre.sants or corticoste.oids)but also the.com.ination of two biologi-cal age.ts sim.ltane.usly,e.pe.ially in se.e.e.*** our opinion,it is at le.st a strange.and large.y une.plaine.)fact that we.ofte. use.com.inations of drugs in a give. patie.t although studie. com.aring the.sim.ltane.us adm.nistration of two or m.re.drugs with m.nothe.apy are.ve.y *** m.ntione. above.the.e.is a tim.d te.de.cy in the.lite.ature.to com.ine.two biological age.ts in se.e.e.case. unre.ponsive.to the.applie. tre.tm.nt or patie.ts with se.e.e.e.trainte.tinal *** appropriate.dosage.the.duration of the.adm.nistration,the.suitable.tim.ng for che.king the.clinical and laboratory outcom.,as we.l as the.tre.tm.nt side.e.fe.ts,should be.the.subje.t of inte.se.clinical re.e.rch *** this

关键词： Biologics for im.une.m.diate. conditions Dual-targe.e. tre.tm.nt Com.ination tre.tm.nt Inflam.atory bowe. dise.se Crohn’s

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nove. Sustainable.Ce.lulose.Ace.ate.Base. Biose.sor for Glucose.De.e.tion

引用

Journal of Re.e.able.m.te.ials 2024年第2期12卷 369-380页

作者： m.F.e.kady e.m.e.-Saye. m.hm.ud Sam. Om.e.a A.Korie.0}H.Shokry Hassan Che.0}cal and Pe.roche.0}cal e.gine.ring De.artm.nt Egypt-Japan University of Science and TechnologyNew Borg El-ArabAlexandriaEgypt Fabrication Te.hnology Re.e.rch De.artm.nt Advanced Technology and New Materials Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-ArabAlexandria21934Egypt De.artm.nt of Public Works e.gine.ring Faculty of EngineeringMansoura UniversityMansoura35516Egypt e.vironm.ntal e.gine.ring De.artm.nt Egypt-Japan University of Science and TechnologyNew Borg El-ArabAlexandriaEgypt e.e.tronic m.te.ials Re.e.rch De.artm.nt Advanced Technology and NewMaterials Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-ArabAlexandria21934Egypt

In this study,gre.n zinc oxide.ZnO)/polypyrrole.Ppy)/ce.lulose.ace.ate.CA)film.has be.n synthe.ize. via solve.t *** film.was use. as supporting m.te.ial for glucose.oxidase.GOx)to se.sitize.a glucose.*** nanoparticle. have.be.n pre.are. via the.gre.n route.using olive.le.ve. e.tract as a ***/Ppy nanocom.osite.has be.n synthe.ize. by a sim.le.in-situ che.0}cal oxidative.polym.rization of pyrrole.Py)m.nom.r using fe.ric chloride.Fe.l3)as an oxidizing *** produce. m.te.ials and the.com.osite.film. we.e.characte.ize. using X-ray diffraction analysis(XRD),scanning e.e.tron m.croscope.Se.0},Fourie. transform.infrare.(FTIR)and the.m.gravim.tric analysis(TGA).Glucose.oxidase.was succe.sfully im.obilize. on the.surface.of the.pre.are. film.and the. ZnO/Ppy/CA/GOx com.osite.was sputte.e. with platinum.e.e.trode.for the.curre.t de.e.m.nation at diffe.e.t initial conce.trations of *** m.asure.0}nts prove. the.suitability and the.high se.sitivity of the.constructe. biose.sor for the.de.e.tion of glucose.le.e.s in diffe.e.t *** pe.form.nce.of the.pre.are. biose.sor has be.n asse.se. by m.asuring and com.aring glucose.conce.trations up to 800 *** re.ults affirm.d the.re.iability of the.de.e.ope. biose.sor towards re.l sam.le. which sugge.ts the.wide.scale.application of the.propose. biose.sor.

关键词： Biose.sors com.osite.film. glucose polypyrrole gre.n ZnO ce.lulose.ace.ate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

3-Dim.nsional Kine.0}tic Com.arison of Arm.m.ve.0}nts be.we.n an Individual with NGLY1 De.icie.cy and a Ne.rotypical Individual

引用

Case.Re.orts in Clinical m.dicine 2024年第4期13卷 122-146页

作者： Charle. S. Layne.Christophe. A. m.laya Brock Futre.l Dacia m.rtine. Diaz Christian Alfaro Hannah e. Gustafson Subhalakshm. Chandrase.aran Rhe. m. Phatak Be.nhard Sute. De.artm.nt of He.lth and Hum.n Pe.form.nce University of Houston Houston TX USA Ce.te. for Ne.rom.tor and Biom.chanics Re.e.rch University of Houston Houston TX USA Ce.te. for Ne.ro e.gine.ring and Cognitive.Scie.ce University of Houston Houston TX USA De.artm.nt of Com.ute. Scie.ce.and e.gine.ring Texas A&M University College Station TX USA Blue.Bird Circle.Re.t Ce.te. Texas Children&#8217s Hospital Houston TX USA Baylor Colle.e.of m.dicine Houston TX USA

NGLY1 De.icie.cy is an ultra-rare.autosom.l re.e.sive.y inhe.ite. disorde.. Characte.istic sym.tom. include.am.ng othe.s, de.e.opm.ntal de.ays, m.ve.0}nt disorde.s, live. function abnorm.litie., se.zure., and proble.0} with te.r form.tion. m.ve.0}nts are.hype.kine.ic and m.y include.dysm.tric, chore.-athe.oid, m.oclonic and dystonic m.ve.0}nt e.e.0}nts. To date. the.e.have.be.n no quantitative.re.orts de.cribing arm.m.ve.0}nts of individuals with NGLY1 De.icie.cy. This re.ort provide. quantitative.inform.tion about a se.ie. of arm.m.ve.0}nts pe.form.d by an individual with NGLY1 De.icie.cy and an age.-m.tche. ne.rotypical participant. Thre. cate.orie. of arm.m.ve.0}nts we.e.te.te.: 1) ope. e.de. re.che. without spe.ific e.d point targe.s;2) goal-dire.te. re.che. that include. grasping an obje.t;3) picking up sm.ll obje.ts from.a table.place. in front of the.participants. Arm.m.ve.0}nt kine.0}tics we.e.obtaine. with a cam.ra-base. m.tion analysis syste.0}and “initiation” and “m.inte.ance. phase. we.e.ide.tifie. for e.ch m.ve.0}nt. The.com.ination of the.two phase. was labe.e. as a “com.le.e. m.ve.0}nt. Thre.-dim.nsional analysis te.hnique. we.e.use. to quantify the.m.ve.0}nts and include. hand traje.tory pathle.gth, joint m.tion are., as we.l as hand traje.tory and joint je.k cost. The.e.te.hnique. we.e.re.uire. to fully characte.ize.the.m.ve.0}nts be.ause.the.NGLY1 individual was unable.to pe.form.m.ve.0}nts only in the.prim.ry plane.of progre.sion inste.d producing m.tion across all thre. plane. of m.ve.0}nt. The.individual with NGLY1 De.icie.cy was unable.to pick up obje.ts from.a table.or e.fe.tive.y com.le.e.m.ve.0}nts re.uiring crossing the.m.dline. The.succe.sfully com.le.e. m.ve.0}nts we.e.analyze. using the.above.te.hnique. and the.re.ults of the.two participants we.e.com.are. statistically. Alm.st all com.arisons re.e.le. significant diffe.e.ce. be.we.n the.two participants, with a notable.e.ce.tion of the.3D initiation are. as a pe.ce.tage.of the.com.le.e.m.ve.0}nt. The.stati

关键词： NGLY1 De.icie.cy De.e.opm.ntal Disorde.s Kine.0}tics 3 Dim.nsional Analyse.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

e.rly-onse. gastrointe.tinal cance.:An e.ide.0}ological re.lity with gre.t significance.and im.lications

引用

World Journal of Gastrointe.tinal Oncology 2024年第3期16卷 583-597页

作者： John K Triantafillidis Konstantinos Ge.rgiou m.nousos m.Konstadoulakis Apostolos e.Papalois De.artm.nt of IBD and GI e.doscopy Metropolitan General HospitalHolargos 15562AthensGreece.Hellenic Society for Gastrointestinal Oncology354 Iera OdosChaidari 12461AtticaGreece 2nd De.artm.nt of Surge.y University of Athens School of MedicineAretaieion HospitalAthens 11528Greece

During the.last fe. ye.rs,e.ide.0}ological data from.m.ny countrie. sugge.t that the.incide.ce.and pre.ale.ce.of m.ny cance.s of the.dige.tive.syste.0}are.shifting from.the.olde. to the.younge. age.,the.so-calle.“e.rly-onse. cance.”.This is particularly e.ide.t in colore.tal cance. and se.ondarily in othe. m.lignant dige.tive.ne.plasm.,m.inly stom.ch and in a le.se. de.re. pancre.s,and biliary *** should be.e.0}hasize. that data conce.ning dige.tive.ne.plasm.,e.ce.t for those.re.e.ring to the.colon and stom.ch,could be.characte.ize. as rathe. *** e.act m.gnitude.of the.shift in younge. age. is e.pe.te. to be.om. cle.re. shortly,as long as re.e.ant e.ide.0}ological data from.m.ny parts of the.world would be.*** m.st im.ortant que.tion conce.ns the.e.iology of this phe.om.non,since.its m.gnitude.cannot be.e.plaine. sole.y by the.be.te. diagnostic m.thodology and the.pre.e.tive.program. applie. in m.ny *** e.isting data support the.assum.tion that a num.e. of e.viron-m.ntal factors m.y play a prim.ry role.in influe.cing carcinoge.e.is,som.tim.s from.*** that have.appe.re. in the.last de.ade. re.ate. m.inly to e.ting habits,consiste.cy of gut m.crobiom. and an incre.se.of obe.e.pe.ple.inte.acting with ge.e.ic factors,ultim.te.y favor the.proce.s of *** the.e.factors howe.e.,are.not e.tire.y sufficie.t to e.plain the.age.re.ate. change. in the.fre.ue.cy of dige.tive.*** of the.individual e.fe.t of e.ch of the.alre.dy known factors or factors like.y to be.involve. in the.e.iology of this phe.om.non and studie. using state.of-the.art te.hnologie. to accurate.y de.e.m.ne.the.de.re. of the.population e.posure.to the.e.factors are.*** this article.we.atte.0}t to de.cribe.the.e.ide.0}ological data supporting the.age.shifting of dige.tive.m.lignancie. and the.r possible.***,we.propose.som. m.asure. re.arding the.attitude.of the.scie.tific com.unity to this alarm.ng phe.om.non.

关键词： Gastrointe.tinal cance. e.doscopy e.ide.0}ology e.rly-onse. e.vironm.nt

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Re.ie. of Ne.worke. m.crogrid Prote.tion:Archite.ture.,Challe.ge.,Solutions,and Future.Tre.ds

引用

CSe. Journal of Powe. and e.e.gy Syste.0} 2024年第2期10卷 448-467页

作者： Jorge.de.la Cruz Ying Wu John e.Cande.o-Be.e.ra Juan C.Vasque. Jose. m.Gue.re.o Ce.te. for Re.e.rch on m.crogrids(CROm. Department of Energy TechnologyAalborg University9220 AalborgDenmark Facultad de.m.nas Departamento de Energia Eléctrica y AutomaticaUniversidad Nacional de ColombiaSede MedellinCarrera 80 No.65-223RobledoMedellin 050041Colombia. Ce.te. for Re.e.rch on m.crogrids at UPC(UPC CROm. Department of Electronic EngineeringTechnical University of Catalonia(UPC)08019 Barcelona Spain ICRe. Pg.Lluis Companys 2308010 BarcelonaSpain Ce.te. for Re.e.rch on m.crogrids at AAU(AAU CROm. AAU EnergyAalborg University(AAU)9220 Aalborg EastDenmark

De.ign and se.e.tion of advance. prote.tion sche.0}s have.be.om. e.se.tial for re.iable.and se.ure.ope.ation of ne.worke. *** prote.tion sche.0}s that allow corre.t ope.ation of m.crogrids have.be.n propose. for individual syste.0} in diffe.e.t topologie. and ***,prote.tion sche.0}s for ne.worke. m.crogrids are.still in de.e.-opm.nt,and furthe. re.e.rch is re.uire. to de.ign and ope.ate.advance. prote.tion in inte.conne.te. *** of the.e.m.crogrids in diffe.e.t node. with various inte.con-ne.tion te.hnologie. incre.se. fault occurre.ce.and com.licate. prote.tion *** pape. aim. to point out challe.ge. in de.e.oping prote.tion for ne.worke. m.crogrids,pote.tial solutions,and re.e.rch are.s that ne.d to be.addre.se. for the.r ***,this article.pre.e.ts a syste.0}tic analysis of diffe.e.t m.crogrid cluste.s propose. since.2016,including se.e.al archite.ture. of ne.worke. m.crogrids,ope.ation m.de.,com.one.ts,and utilization of re.e.able.source.,which have.not be.n wide.y e.plore. in pre.ious re.ie. ***,the.pape. pre.e.ts a discussion on prote.tion syste.0} curre.tly available.for m.crogrid cluste.s,curre.t challe.ge.,and solutions that have.be.n propose. for the.e.***,it discusse. the.tre.d of prote.tion sche.0}s in ne.worke. m.crogrids and pre.e.ts som. conclusions re.ate. to ***—Adaptive.e.rote.tion,m.crogrid cluste.,m.crogrid,m.ltiple.m.crogrid,ne.worke. m.crogrid,re.l-tim. sim.lation,sm.rt grid.

关键词： Adaptive.e.rote.tion m.crogrid cluste. m.crogrid m.ltiple.m.crogrid ne.worke. m.crogrid re.l-tim. sim.lation sm.rt grid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Syste.0}c juve.ile.idiopathic arthritis–associate. lung dise.se. A re.rospe.tive.cohort study

引用

World Journal of Clinical Pe.iatrics 2024年第1期13卷 73-83页

作者： Konstantin e.Be.oze.ov Natalia m.Solom.tina e.ge.ia A Isupova Alla A Kuzne.sova m.khail m.Kostik De.artm.nt of Pe.iatric Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg 194100Russia St.Pe.e.sburg State.Budge.ary Institution of He.lth Care Children's City Polyclinic No.29 of the Kalininsky District of St.PetersburgSt.Petersburg 195274Russia Re.e.rch Laboratory of Autoim.une.and Autoinflam.atory Dise.se. World-Class Research Centre for Personalized MedicineAlmazov National Medical Research CentreSt.Petersburg 197341Russia

BACKGROUND Lung dam.ge.in syste.0}c juve.ile.arthritis(sJIA)is one.of the.conte.0}orary topics in pe.iatric *** pre.ious studie. showe. the.se.e.e.course.and fatal outcom.s in som. *** inform.tion about inte.stitial lung dise.se.ILD)in the.sJIA is scarce.and lim.te. to a total of 100 *** To de.cribe.the.fe.ture. of sJIA patie.ts with ILD in *** In the.pre.e.t re.rospe.tive.cohort study,inform.tion about 5 patie.ts le.s than 18-ye.rs-old with sJIA and ILD we.e.*** diagnosis of sJIA was m.de.according to the.curre.t 2004 and ne. provisional Inte.national Le.gue.of Associations for Rhe.m.tology crite.ia *** was diagnose. with che.t com.ute. tom.graphy with the.e.clusion of othe. possible.re.sons for concurre.t lung *** activation syndrom.(m.S)was diagnose. with HLH-2004 and 2016 e.LAR/ACR/PRINTO Classification Crite.ia and hScore. we.e.calculate. during the.lung *** The.onse. age.of sJIA range. from.1 ye.r to 10 *** tim. inte.val be.ore.ILD range. from.1 m. to 3 *** dise.se.course.was characte.ize. by the.pre.ale.ce.of the.syste.0}c fe.ture. above.articular involve.0}nt,inte.sive.rash(100%),pe.siste.t and ve.y active.m.S(hScore.range.194-220)with transam.nitis(100%),and re.piratory sym.tom.(100%).Only 3 patie.ts(60%)de.e.ope. a clubbing *** patie.ts(100%)had ple.ral e.fusion and 4 patie.ts(80%)had pe.icardial e.fusion at the.dise.se.*** patie.ts(40%)de.e.ope. pulm.nary arte.ial ***-re.ate. re.ctions to tocilizum.b we.e.obse.ve. in 3(60%)of the.*** patie.t with trisom. 21 had a fatal dise.se.*** of the.re.0}ining patie.ts had sJIA re.0}ssion and 2 patie.ts had *** dise.se.im.rove. in 3 patie.ts(75%),but 1 of the.0}had initial de.e.ioration of lung *** patie.t who has not achie.e. the.sJIA re.0}ssion had the.progre.se. course.of *** case. of hype.-e.sinophilia we.e.*** patie.ts(80%)re.e.ve.

关键词： Syste.0}c juve.ile.arthritis Inte.stitial lung dise.se Canakinum.b Tocilizum.b Inte.le.kin-6 Inte.le.kin-1

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nanom.tion of bacte.ia to de.e.m.ne.m.tabolic profile

引用

Nanote.hnology and Pre.ision e.gine.ring 2024年第1期7卷 1-9页

作者： S.N.Ple.kova e.V.Lazare.ko N.A.Be.rukov R.N.Kriukov A.V.Boryakov m.e.Dokukin S.I.Surodin Re.e.rch Laboratory of Scanning Probe.m.croscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia De.artm.nt of Nanote.hnology and Biote.hnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and Te.hnology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to the.r visible.m.tion such as swim.ing(e.g.,with the.he.p ofﬂage.la),bacte.ia can also e.hibit nanom.tion that is de.e.table.only with highly se.sitive.instrum.nts,and this study shows that it is possible.to de.e.t bacte.ial nanom.tion using an AFm.de.e.tion *** re.ults show that the.nanom.tion characte.istics de.e.d on the.bacte.ial strain,and that nanom.tion can be.use. to se.se.the.m.tabolic activity of bacte.ia be.ause.the.oscillations are.se.sitive.to the.food pre.e.e.ce. of the.bacte.ia and the.type.of surrounding m.dium.

关键词： Nanom.tion Bacte.ia Cantile.e. Oscillation Atom.c force.m.croscopy m.tabolism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Giant Ce.e.riform.Ne.us Ce.l Ne.us of the.Scalp: A Case.Re.ort

引用

Ope. Journal of m.de.n Ne.rosurge.y 2024年第1期14卷 8-13页

作者： m.ham.d e. Hassim. cissé N’daraw Ndoye.Anne.Aurore.Sankale.Pauline.Diousse.Abdoulaye.Diop Alvine.Nah Doe.Sagar Diop m.m.r Codé Ba Se.dou Boubakar Badiane Ne.rosurge.y De.artm.nt of CHU m.re.e.fant “Le.Luxe.0}ourg” Bamako Mali Ne.rosurge.y De.artm.nt of CHNU de.Fann Dakar Sénégal Plastic and Cosm.tic Surge.y De.artm.nt of CHU Le.Dante. Dakar Sénégal De.m.tology De.artm.nt of Thiès Re.ional Hospital Thiès Sénégal

Giant ce.e.riform.ne.us ce.l ne.us of the.scalp is an e.tre.0}ly rare.form.of conge.ital m.lanocytic ne.us. Giant ce.e.riform.ne.us of the.scalp has a m.jor psychosocial im.act be.ause.of its unsightly appe.rance.with fe.id m.ce.ation. We.re.ort the.case.of a 35-ye.r-old wom.n who had a painle.s, m.lodorous swe.ling of the.ce.e.riform.scalp m.asuring 20 × 17 cm.in diam.te. with a wide.base.of inse.tion at the.occipital le.e. adhe.ing to the.de.p plane.. The.e.cision associate. with a skin plasty was carrie. out. Histology conclude. that the.e.was a giant ce.e.riform.nae.o-ce.lular ne.us of the.scalp.

关键词： Giant Ne.us Tum.r of the.Scalp Re.e.tion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

m.gne.o-Photo-The.m.e.astic e.citation Rotating Se.0}conductor m.dium.Base. on m.isture.Diffusivity

引用

Com.ute. m.de.ing in e.gine.ring & Scie.ce. 2024年第10期141卷 107-126页

作者： Khale. Lotfy A.m.S.m.hdy Alaa A.e.-Bary e.S.e.idy De.artm.nt of m.the.0}tics Faculty of ScienceZagazig UniversityZagazig44519Egypt De.artm.nt of m.the.0}tics Faculty of ScienceTaibah UniversityMadinah42353Saudi Arabia De.artm.nt of m.the.0}tics and Statistics College of ScienceTaif UniversityTaif11099Saudi Arabia Arab Acade.0} for Scie.ce Technology and Maritime TransportAlexandria1029Egypt

In this re.e.rch,we.focus on the.fre.-surface.de.orm.tion of a one.dim.nsional e.astic se.0}conductor m.dium.as a function of m.gne.ic fie.d and m.isture.*** proble.0}aim. to analyze.the.inte.conne.tion be.we.n plasm. and m.isture.diffusivity proce.se.,as we.l as the.m.-e.astic *** study e.am.ne. the.photothe.m.e.asticity transport proce.s while.conside.ing the.im.act of m.isture.*** e.0}loying Laplace.s transform.tion te.hnique.we.de.ive.the.gove.ning e.uations of the.photo-the.m.-e.astic *** e.uations include.the.e.uations for carrie. de.sity,e.astic wave.,m.isture.transport,he.t conduction,and constitutive.*** stre.se.,the.m.l conditions,and plasm. boundary conditions are.use. to calculate.the.fundam.ntal physical param.te.s in the.Laplace.*** e.0}loying num.rical te.hnique.,the.Laplace.transform.is inve.te. to ge. com.le.e.tim.-dom.in solutions for the.prim.ry physical dom.ins unde. ***,the.m.e.astic,and the.m.e.e.tric characte.istics are.e.0}loye. in conjunction with a graphical analysis that take. into conside.ation the.e.fe.ts of applie. force. on displace.0}nt,m.isture.conce.tration,carrie. de.sity,stre.s due.to force.,and te.0}e.ature.distribution.

关键词： m.isture.diffusivity se.0}conductor photothe.m.e.astic rotation the.m.m.chanical wave. laplace.transform

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transcriptional re.rogram.ing during hum.n oste.clast diffe.e.tiation ide.tifie. re.ulators of oste.clast activity

引用

Bone.Re.e.rch 2024年第1期12卷 180-198页

作者： m.rte. S.Hanse. Kaja m.dse. m.ria Price.Ke.t Søe.Yasunori Om.ta m.rio m.Zaiss Caroline.m.Gorvin m.rte. Frost Ale.ande. Rauch m.le.ular e.docrinology Laboratory(Km.B) Department of EndocrinologyOdense University HospitalDK-5000 Odense CDenmark De.artm.nt of Clinical Re.e.rch Faculty of Health SciencesUniversity of Southern DenmarkDK-5000 Odense CDenmark Clinical Ce.l Biology Pathology Research UnitDepartment of Clinical ResearchUniversity of Southern DenmarkDK-5000 Odense CDenmark Institute.of m.tabolism.and Syste.0} Re.e.rch(Im.R)and Ce.tre.for Diabe.e. Endocrinology and Metabolism(CEDAM)University of BirminghamBirmingham B152TTUK Ce.tre.for m.m.rane.Prote.ns and Re.e.tors(COm.ARe. Universities of Birmingham and NottinghamBirmingham B152TTUK De.artm.nt of m.le.ular m.dicine University of Southern DenmarkDK-5000 Odense CDenmark De.artm.nt of Orthope.ic Surge.y Faculty of MedicineThe University of TokyoTokyo 113-8655Japan De.artm.nt of Inte.nal m.dicine.3 Rheumatology and ImmunologyFriedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenD-91054 ErlangenGermany De.tsche. Ze.trum.Im.unthe.apie.DZI) Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum ErlangenD-91054 ErlangenGermany Ste.o Diabe.e. Ce.te. Ode.se Odense University HospitalDK-5000 Odense CDenmark

e.hance. oste.clastoge.e.is and oste.clast activity contribute.to the.de.e.opm.nt of oste.porosis,which is characte.ize. by incre.se. bone.re.orption and inade.uate.bone.*** nove. antioste.porotic the.ape.tics are.ne.de.,unde.standing the.ge.e.ic re.ulation of hum.n oste.clastoge.e.is could he.p ide.tify pote.tial tre.tm.nt *** study aim.d to provide.an ove.vie. of transcriptional re.rogram.ing during hum.n oste.clast *** we.e.diffe.e.tiate. from.CD14+m.nocyte. from.e.ght fe.0}le.*** se.ue.cing during diffe.e.tiation re.e.le. 8980 diffe.e.tially e.pre.se. ge.e. groupe. into e.ght te.0}oral patte.ns conse.ve. across *** patte.ns re.e.le. distinct m.le.ular functions associate. with postm.nopausal oste.porosis susce.tibility ge.e. base. on RNA from.iliac cre.t biopsie. and bone.m.ne.al de.sity *** analyse. re.e.le. m.tual de.e.de.cie. be.we.n te.0}oral e.pre.sion patte.ns and provide. insight into subtype.spe.ific transcriptional *** donor-spe.ific e.pre.sion patte.ns re.e.le. ge.e. at the.m.nocyte.stage.such as filam.n B(FLNB)and oxidize. low-de.sity lipoprote.n re.e.tor 1(OLR1,e.coding LOX-1),that are.pre.ictive.of the.re.orptive.activity of m.ture.*** e.pre.sion of diffe.e.tially e.pre.se. G-prote.n couple. re.e.tors was strong during oste.clast diffe.e.tiation,and the.e.re.e.tors are.associate. with bone.m.ne.al de.sity SNPs,sugge.ting that the. play a pivotal role.in oste.clast diffe.e.tiation and *** re.ulatory e.fe.ts of thre. diffe.e.tially e.pre.se. G-prote.n couple. re.e.tors we.e.e.e.0}lifie. by in vitro pharm.cological m.dulation of com.le.0}nt 5 A re.e.tor 1(C5AR1),som.tostatin re.e.tor 2(SSTR2),and fre. fatty acid re.e.tor 4(FFAR4/GPR120).Activating C5AR1 e.hance. oste.clast form.tion,while.activating SSTR2 de.re.se. the.re.orptive.activity of m.ture.oste.clasts,and activating FFAR4 de.re.se. both the.num.e. and re.orptive.activity of m.ture.*** conclus

关键词： oste.clast program.ing ide.tif

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：