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The im.act of Age and Gender on Severity and Types of Periodontal Diseases am.ng Patients from.Two Regions in Saudi Arabia

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Open Journal of Stom.tology 2019年第3期9卷 39-50页

作者： m.ham.ed m. A. Abdullah Al-Abdaly Hussain Saad Hussain AlQahtani Sultan Saeed Hadi Al-Qahtani Periodontics and Com.unity Dental Sciences Departm.nt College of Dentistry King Khalid University Abha Saudi Arabia m.nistry of Health Al-Wajh Saudi Arabia College of Dentistry King Khalid University Abha Saudi Arabia

Background: Periodontitis is the predom.nant disease in the oral cavity and there are alterations in the periodontal tissues associated with the aging and gender of the patient. Objective: The present study was designed to assess the im.act of age and gender of the patient on severity and types of periodontal diseases am.ng patients from.two regions in Saudi Arabia. m.terials and m.thods: The current study was done on 600 Saudi patients from.Aseer and Tabuk regions in Saudi Arabia (50% m.les and 50% fem.les) and divided into three equal groups (n = 200) according to the patients age: children and young patients (1 - 24 years old), adults patients (25 - 64 years old) and seniors patients (m.re than 65 years old). Plaque index (PLi), gingival index (Gi), periodontal pocket depth (PPD) and clinical attachm.nt loss (cal) were recorded from.all participants. The data were collected and analyzed with SPSS to determ.ne the m.an and standard deviation (±SD) and the values of significance (P ≤ 0.005). Results: The results of the present study revealed that 340 patients (56.7%) were affected with gingivitis dental biofilm.induced and 260 patients were affected by periodontitis. Gingivitis dental biofilm.induced is especially detected in children and young patients (33.3%), adult patients (16.7%) and seniors patients (6.7%) whereas periodontitis cases were seen am.ng the adult and seniors patients (16.7%) and (26.6%) respectively. Furtherm.re, the present study displayed the higher severity and prevalence of gingivitis dental biofilm.induced and periodontitis am.ng fem.les m.re than m.les in group ii and group iii m.ybe due to horm.nal changes. The present study saw that there are statistically significant differences in clinical findings in the com.arison between groups of this study (P ≤ 0.005). Conclusion: We conclude that there is a relation between severity and types of periodontal diseases and the ages and genders of Saudi patients in Aseer and Tabuk regions, Saudi Arabi

关键词： Aseer Periodontal Diseases Tabuk Saudi Arabia

A Finite Difference m.thod for Space Fractional Differential Equations with Variable Diffusivity Coefficient

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Com.unications on Applied m.them.tics and Com.utation 2020年第4期2卷 671-688页

作者： K.A.m.stapha K.m.Furati O.m.Knio O.P.Le m.ître Departm.nt of m.them.tics and Statistics King Fahd University of Petroleum and MineralsDhahran 31261Kingdom of Saudi Arabia Com.uter ElectricalMathermatical Sciences and Engineering DivisionKing Abdullah University of Science and TechnologyThuwal 23955Kingdom of Saudi Arabia CNRS LIMSIUniversitéParis-SaclayCampus Universitaire-BP 13391403 OrsayFrance

Anom.lous diffusion is a phenom.non that cannot be m.deled accurately by second-order diffusion equations,but is better described by fractional diffusion *** nonlocal nature of the fractional diffusion operators m.kes substantially m.re difficult the m.them.ti-cal analysis of these m.dels and the establishm.nt of suitable num.rical *** paper proposes and analyzes the first finite difference m.thod for solving variable-coefficient one-dim.nsional(steady state)fractional differential equations(DEs)with two-sided fractional derivatives(FDs).The proposed schem. com.ines first-order forward and backward Euler m.thods for approxim.ting the left-sided FD when the right-sided FD is approxim.ted by two consecutive applications of the first-order backward Euler *** schem. reduces to the standard second-order central difference in the absence of *** existence and uniqueness of the num.rical solution are proved,and truncation errors of order h are dem.nstrated(h denotes the m.xim.m.space step size).The num.rical tests illustrate the global 0(h)accu-racy,except for nonsm.oth cases which,as expected,have deteriorated convergence rates.

关键词： Two-sided fractional derivatives Variable coefcients Finite diferences

俄罗斯远东地区近4000年以来植被变化和火灾记录

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俄罗斯远东地区近4000年以来植被变化和火灾记录

从调控T淋巴细胞亚群失衡探讨健脾益气法改善支气管哮喘缓解期气道炎症的免疫学机制

中国古生物学会孢粉学分会八届二次学术年会

作者：余少华郑卓 m.i.Skrypnikova 中山大学地球科学系

俄罗斯远东地区作为高纬度的湿地沼泽,其自然环境的变化对整个地球碳循环具有重要影响。本文通过选择俄罗斯阿穆尔河流域的Am.r 23钻孔的64个样品进行花粉研究,并且对整个区域进行植被调查,通过与40个表土花粉样点进行对比研究,来恢复... 详细信息

俄罗斯远东地区作为高纬度的湿地沼泽,其自然环境的变化对整个地球碳循环具有重要影响。本文通过选择俄罗斯阿穆尔河流域的Am.r 23钻孔的64个样品进行花粉研究,并且对整个区域进行植被调查,通过与40个表土花粉样点进行对比研究,来恢复俄罗斯远东地区近4000年以来的植被和气候变化;同时,通过定量分析碳屑数据,并与孢粉数据进行对比,来探究碳屑物质来源,以及火灾频率和程度大小,以此更加深入的了解人类活动对整个自然环境的影响。结果分析表明,俄罗斯远东地区的植被和气候变化可以分为四个时期:距今4000-3000 cal a B.P.,主要表现为温暖湿润气候,植被主要以温带阔叶林为主,碳屑分析表明此段时间内碳屑物质来源主要为草本植物,且多为区域火,火灾频率较低,为370年/次,此时沼泽已经开始发育,植被环境受到人类活动影响不大。距今3000-1500 cal a B.P.,此时期气候温和湿润,植被以温带阔叶林、湿生草甸为主,此时为沼泽大发展时期,其中从2000 cal a B.P.开始,人类活动影响加剧;此段时期内火灾多为当地火,且频率显著增高,火灾有5次高峰期,其火灾频率为182年/次,表明此时沼泽发育与古环境演变受到自然因素和人类活动的双重影响。距今1500-500 cal a B.P.,此段时期内气候寒冷潮湿,针叶林生长广泛,其火灾频率也有所增高,达到165年/次;此时沼泽发育开始进入衰退期,并且受到人类活动剧烈影响。距今500 cal a B.P.以来,气候寒冷干燥,沼泽发育进入衰退期。此时碳屑总浓度有显著增长,且火灾频率在此带内最高,达到125年/次。说明人类活动影响强烈,此时气候变得干冷,沼泽发育进入晚期,阿穆尔平原上的草甸开始向旱生草地退化。

关键词：俄罗斯远东花粉碳屑古环境人类活动

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中医杂志 2021年第10期62卷 856-860,880页

作者：金华良周燕王利民叶健厉蓓蔡萃浙江大学医学院附属杭州市第一人民医院浙江省杭州市310006 南京医科大学附属杭州医院浙江省杭州市红十字会医院

支气管哮喘(简称"哮喘")是临床常见的气道炎症性疾病,T淋巴细胞亚群在哮喘气道炎症机制中发挥重要作用,其中效应性T细胞与调节性T细胞免疫失衡是主要机制。中医学认为,"伏痰"是哮喘缠绵难愈的宿根,正气亏虚是伏痰产生的根本原因,脾虚失... 详细信息

支气管哮喘(简称"哮喘")是临床常见的气道炎症性疾病,T淋巴细胞亚群在哮喘气道炎症机制中发挥重要作用,其中效应性T细胞与调节性T细胞免疫失衡是主要机制。中医学认为,"伏痰"是哮喘缠绵难愈的宿根,正气亏虚是伏痰产生的根本原因,脾虚失运是伏痰产生的关键所在,因此健脾益气、扶正祛伏痰应是哮喘重要治法。伏痰与现代医学所谓的哮喘气道炎症有相通之处,因此可从调控T淋巴细胞亚群失衡来探讨健脾益气法改善哮喘气道炎症的免疫学机制,其中通过改善调节性T细胞功能来恢复其与效应性T细胞之间的平衡,可能是健脾益气法的作用机制之一。

关键词：支气管哮喘健脾益气法伏痰气道炎症 T淋巴细胞

The influence of Kidney Stones and Salivary Uric Acid on Dental calculus Form.tion and Periodontal Status am.ng Som. Saudi Patients Aged 25 - 70 Years

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international Journal of Clinical m.dicine 2020年第10期11卷 565-578页

作者： m.ham.ed m. A. Abdullah Al-Abdaly Fayez Saud Thlaab Alharbi Ali m.ham.ed Alm.alem.Nasser Ahm.d Taib Awaji Periodontics and Com.unity Dental Sciences Departm.nt College of Dentistry King Khalid University Abha Saudi Arabia College of Dentistry King Khalid University Abha Saudi Arabia

Background: The form.tion of kidney stones is considered a com.licated process. Consequently, there are m.ny questions about the link between kidney stones form.tion and level of salivary uric acid and calculus form.tion on the teeth surfaces. Objectives: To evaluate the correlation between the level of salivary uric acid and kidney stones form.tion and their influence on dental calculus and periodontal status am.ng Saudi patients aged 25 - 70 years. m.terials and m.thods: 120 Saudi m.le patients were exam.ned (60 of Kidney stones patients and 60 patients of non-kidney stones patients) for clinical evaluation of plaque index (PLi), gingival index (Gi), calculus index of oral hygiene (Ci) and clinical attachm.nt loss (cal). m.reover, lab assessm.nt of uric acid level in the collected salivary sam.les was done. The findings were analyzed using of ANOVA test and Tukey’s test. Results: There were statistically significant differences in clinical param.ters am.ng kidney stones patients and non-kidney stones patients (p ifferences were highly statistically significant in the correlation between calculus index (Ci), plaque index (PLi) and gingival index (Gi) am.ng kidney stone patients in group ii, m.reover, PLi and clinical attachm.nt loss (cal) am.ng kidney stone patients in group iii (p istical analyses revealed statistically significant differences in the level of salivary uric acid (m./dl) in the com.arison between kidney stones patients and non-kidney stones patients in group i and group iii, whereas there were highly statistically significant in the com.arison between kidney stones patients and non-kidney stones patients in group iii. Conclusion: At the end of this study, we concluded that there was a relationship between dental calculus form.tion, kidney stones form.tion, and an increase in the level of salivary uric acid.

关键词： Dental calculus Kidney Stones Uric Acid Periodontal Status

Regulatory T cells in inflam.atory bowel diseases and colorectal cancer

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World Journal of Gastroenterology 2012年第40期18卷 5688-5694页

作者： Gyrgyi m.zes Béla m.lnár Ferenc Sipos 2nd Departm.nt of internal m.dicine Semmelweis University m.lecular m.dicine Research Unit Hungarian Academy of Sciences

Regulatory T cells(T regs) are key elem.nts in im.unological *** num.er of T regs m.y alter in both peripheral blood and in colonic m.cosa during pathological *** local cellular,m.crobiological and cytokine m.lieu affect im.unophenotype and function of T *** box P3+ T regs function shows altered properties in inflam.atory bowel diseases(iBDs).This alteration of T regs function can furtherm.re be observed between Crohn's disease and ulcerative colitis,which m.y have both clinical and therapeutical *** m.cosal inflam.ation m.y also influence T regs function,which together with the intestinal bacterial flora seem.to have a supporting role in colitis-associated colorectal carcinogenesis.T regs have a crucial role in the im.unoevasion of cancer cells in sporadic colorectal ***,their num.er and phenotype correlate closely with the clinical outcom. of the disease,even if their contribution to carcinogenesis has previously been *** knowledge of the clinical relationship between iBD and colitis-associated colon cancer,and the growing num.er of im.unological aspects encom.assing sporadic colorectal carcinogenesis,the m.lecular and cellular links am.ngst T regs,regulation of the inflam.ation,and cancer developm.nt are still not well *** this paper,we aim.d to review the current data surrounding the role of T regs in the pathogenesis of iBD,colitis-associated colon cancer and sporadic colorectal cancer.

关键词： Regulatory T cells Forkhead box P3 inflam.m.tory bowel diseases Colitis-associated colon cancer Colorectal cancer

Oral Health Status and Gingival Response to Three Different Restorative m.terials am.ng Saudi Patients: A Clinical &am.;Histopathological Study

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international Journal of Clinical m.dicine 2019年第2期10卷 78-90页

作者： m.ham.ed m. A. Abdullah Al-Abdaly Hassan m.ham.ed Al-Harthi Salem.m.ham.ed Al-Harthi Redwan Abdullah Ali Alm.lki Periodontics and Com.unity Dental Sciences Departm.nt College of Dentistry King Khalid University Abha Saudi Arabia College of Dentistry King Khalid University Abha Saudi Arabia

Background: The correlation between oral health and dental restoration is fundam.ntal. For the gingival and periodontal tissues to stay healthy, dental restoration should be in regularity with the surrounding tissues. This study aim. to assess the oral health status and histopathological gingival response to three different restorative m.terials am.ng Saudi patients. m.thods: The study groups consist of 240 patients (50% m.les and 50% fem.les), aged 18 - 45, with inclusion and exclusion criteria in the study. Participants are divided into three equal groups: those with com.osite resin restorations, those with am.lgam.restorations and those with glass ionom.r restorations. Biopsies were taken from.adjacent gingival tissues. Clinical param.ters were determ.ned by: plaque index (PLi), gingival index (Gi) and clinical attachm.nt loss (cal). All data were collected and evaluated by through statistical analysis. Results: The clinical findings of the current study revealed that am.lgam.restorations produce a higher m.ans of PLi, Gi and cal com.ared with com.osite resin restorations and glass ionom.r restorations, but not insignificant levels, except cal (p = 0.004*). As for histopathological findings, there were significant differences in gingival tissue response to am.lgam.restorations, com.osite resin restorations and glass ionom.r cem.nt fillings, where there were statistically significant differences in num.ers of chronic inflam.atory cells (p Conclusion: At the end of the present study, we concluded that the am.lgam.restorations are less biocom.atible com.ared to com.osite resin restorations and glass ionom.r restorations.

关键词： Gingival Response Histopathological Study Oral Health Status

Periodontal Tissue Status am.ng m.ntal Retardation Patients with Fixed Prosthodontic Appliances

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international Journal of Clinical m.dicine 2018年第1期9卷 49-58页

作者： m.ham.ed m. A. Abdullah Al-Abdaly Abdulaziz m.shabbab Abu Qahas Abdullah m.shabbab Ali Honbos Abdulrahm.n Ahm.d Abdullah Alshehri College of Dentistry King Khalid University Abha Saudi Arabia m.nistry of Health Bisha Saudi Arabia

Background: The m.ntal, physical and social im.edim.nts cause lim.tation of chances in norm.l life as an equal level with others of the com.unity;particularly in relation to m.intain good oral hygiene and periodontal health am.ng the disabled patients who were receiving fixed partial denture. So the present study was perform.d to evaluate the periodontal tissue status am.ng m.ntal retardation patients with fixed prosthodontic appliances. Subjects and m.thods: A total of 400 patients between the ages 18 and 50 years were clinically selected from.outpatient clinics, college of dentistry, King Khalid University and rehabilitation center in Abha city, Saudi Arabia. They were divided into two equal groups as the following: group i: Two hundred m.ntal retardation patients without fixed prosthodontic appliances (control group) and, group ii: Two hundred m.ntal retardation patients had fixed prosthodontic appliances for at least a year ago. A com.lete periodontal clinical exam.nation was perform.d and the following indices were recorded: plaque index (PLi), gingival index (Gi), and clinical attachm.nt loss (cal). All data was recorded and analyzed by ANOVA test. Results: The clinical results of the present study confirm.d the relationship am.ng the m.ntal retardation, fixed prosthodontic appliances and destruction of periodontal tissues. it has been found that the severity of periodontal disease increases am.ng the study group com.ared to the control group. Statistically significant differences were found in PLi, Gi and cal.in the com.arison between group i and ii (p Conclusion: There was a negative relationship between m.ntal retardation with a status of periodontal tissues and oral hygiene am.ng the patients under fixed prosthodontic m.nagem.nt.

关键词： Fixed Prosthodontic Appliances m.ntal Retardation Periodontal Tissue Status

DAYLiGHT iN A CiSTERCiAN HERiTAGE CHURCH iN LiSBON,FROm.RURAL TO URBAN CONTEXT

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Journal of Green Building 2014年第3期9卷 116-130页

作者： Jorge S.Carlos Ana m.T.m.rtins Centre of m.terials and Building Technologies University of Beira InteriorCalçada Fonte do Lameiro6201-001 CovilhãPortugal Departm.nt of Civil Engineering and Architecture University of Beira Interior/CITADResearch Centre in TerritoryArchitecture and DesignLisbonPortugalCalçada Fonte do Lameiro6201-001 CovilhãPortugal.

Light levels in the churches of the Cistercian Order are m.stly related to the fulfilm.nt of liturgical *** com.ound building of Bernardas’Convent includes a church at the utm.st southern corner that dates back to the 17th *** only has one façade facing due *** paper analyses the relationship between daylight conditions within the building before and after the urbanisation of the surrounding area;taking into account the relationship between the church,its m.in activities,and solar trajectory.A com.arative analysis of the relationship between the actual surrounding context and the initial period after it was built(open field)is *** highest reflectance of the street canyon has augm.nted the levels of available daylight.

关键词： Sun-path Daylight factor Vertical daylight factor Urban canyon Cistercians Heritage