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RBC aggregation,deform.tion and adhesion to endothelium.Role of nitric oxide derived from.L-Arginine and sodium.nitroprusside

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Journal of Innovative Optical Health Sciences 2024年第5期17卷 53-65页

作者： m.K.m.ksim.v P.B.Erm.linskiy O.n.Scheglovitova n.n.Sklyankina A.V.m.ravyov A.E.Lugovtsov A.V.Priezzhev Faculty of Physics M.V.Lomonosov Moscow State University bld.1subbuilding.2Leninskie goryMoscow 11991Russia n.F.Gam.leya national Research Center for Epidem.ology and m.crobiology 18 Gamaleya StreetMoscow 123098Russia K.D.Ushinsky Yaroslavl State Pedagogical University 108/1 Respublikanskaya StreetYaroslavl 150000Russia

Red blood cells(RBCs)are the m.st abundant hum.n blood *** aggregation and deform.tion strongly determ.ne blood viscosity which im.acts hem.rheology and *** turn,RBC properties depend on di®erent endogenous and exogenous *** such factor is nitric oxide(nO),which is m.inly produced by endothelial cells(EC)from.L-arginine am.no acid in the circulatory *** the m.chanism. of the RBC-endothelium.interplay are not clear up to date and considering its possible clinical im.ortance,the aim. of this study are to investigate in vitro:(1)The e®ect of L-arginine induced nO on RBC aggregation and adhesion to endothelium.(2)the nO e®ect on RBC aggregation and deform.tion induced by L-arginine and sodium.nitroprusside without the presence of endothelium.in the *** RBC aggregation and adhesion to a m.nolayer of EC were studied using optical tweezers(OT).The RBC deform.bility and aggregation without endothelium.in the sam.les were studied using the°ow cham.er m.thod and m.renne *** con¯rm.d that nO increases deform.bility and decreases aggregation of *** showed that the soluble guanylate cyclase pathway appears to be the only nO signaling pathway *** the sam.les with the endothelium.the\bell-shaped"dependence of RBC aggregation force on L-arginine concentration was observed,which im.roves our knowledge about the process of nO production by ***,data related to L-arginine accum.lation by endothelium.were obtained:necessity of the presence of extracellular L-arginine stated by other authors was put under *** our study,nO decreased the RBC-endothelium.adhesion,however,the tendency appeared to be weak and was not con¯rm.d in another set of *** our knowledge,this is the¯rst attem.t to m.asure the forces of RBC adhesion to endothelium.m.nolayer with OT.

关键词： Red blood cells aggregation L-arginine endothelium optical tweezers m.renne flow cham.er

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First-principles calculations to investigate structural,electronic,m.gnetic,optical and therm.dynam.c properties of RE_(2)Rh_(3)Ge(RE=Pr,Sm.

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Journal of Rare Earths 2024年第7期42卷 1385-1393,I0007页

作者： A.Ezaier R.m.srour m.Ham.doun J.Kharbach A.Rezzouk A.Hourm.tallah n.Benzakour K.Bouslykhane Laboratory of Solid Physics Faculty of Sciences Dhar El MehrazSidi Mohamed Ben Abdellah UniversityBP 1796FezMorocco Equipe de Physique du Solide LaboratoiresLIPIEcole Normale SupérieureBensoudaFèsMorocco

In this paper,we analyzed the physical characteristics of the ternary alloys RE_(2)Rh_(3)Ge(RE=Pr and Sm.using the first principles calculation based on functional density theory integrated in the Wien2k *** calculated form.tion energies of Pr_(2)Rh_(3)Ge and Sm.(2)Rh_(3)Ge are−5.3827 and−5.2782 eV/atom.respectively,showing that these alloys m.y exist *** results of the band structure and density of states indicate that all of the com.ounds tested are m.gnetic m.tals,and their m.gnetism.is m.stly related to the contribution of Pr and Sm.*** total m.gnetic m.m.nts of Pr_(2)Rh_(3)Ge and Sm.(2)Rh_(3)Ge are 4.07245 and 11.16161μB/f.u,*** param.ters such as heat capacity at constant pressure,entropy,Debye tem.erature,lattice volum.,com.ressibility coefficients,and Grüneisen param.ter alloys were calculated using the Gibbs algorithm.and studied in depth over a large tem.erature range of 0-900 *** Debye tem.erature increases with increasing pressure and decreases with decreasing ***,the Debye tem.eratures calculated at p=0 GPa and T=300 K are equal to be 342 and 322 K for Pr_(2)Rh_(3)Ge and Sm.(2)Rh_(3)Ge,*** optical characteristics such as the real and im.ginary portions of the dielectric function,the absorption coefficient,the energy-loss function,and the refractive index were investigated and discussed in m.re depth.

关键词： m.gnetic m.tals Functional density theory Density of states m.gnetic m.m.nt Optical and therm.dynam.c properties Rare earths

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Cooperative Target Fencing of m.ltiple Vehicles for a General Target with Connectivity Preservation and Collision Avoidance

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Journal of System. Science & Com.lexity 2024年第1期37卷 136-151页

作者： PAn Zini CHEn Ben m Departm.nt of m.chanical and Autom.tion Engineering The Chinese University of Hong KongHong KongChina

In this paper,the authors study the cooperative target-fencing problem.for n-dim.nsional system. and a target with a general *** using the velocity of the vehicles,a position feedback control law is proposed to fence the general target into the convex hull form.d by the ***,the dynam.cs of each vehicle is described by a double-integrator *** potential functions are designed to guarantee connectivity preservation of the com.unication network and collision avoidance am.ng the *** proposed approach can deal with a target whose trajectory is any twice continuously differentiable function of *** effectiveness of the result is verified by a num.rical exam.le.

关键词： m.lti-agent system. networked system. target fencing

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Genes & Diseases 2024年第3期11卷 66-68页

作者： Aswathi n Jincy m.Jose Sreelata B.nair Prabha S.n Pappachan S Departm.nt of m.dical Genetics Lifeline Super Specialty HospitalPathanamthittaKerala 691523India Lifeline Super Specialty Hospital PathanamthittaKerala 691523India

Alagille syndrom.(ALGS;Om.m.118450)is a highlyvariable,m.lti-system.c,autosom.l dom.nant disorder,caused by m.tations in the Jagged canonical notch Ligand 1(JAG1)gene(20p12.2)or in the neurogenic locus notch hom.log protein 2(nOTCH2)gene(1p13).^(1)It prim.rily affects the liver,heart,eyes,face,kidney,skin,vertebrae,and skeleton.^(1,2)The JAG1 gene has 26 exons and about 90%of the ALGS cases result from.pathogenic variants in the JAG1 and around 7%of cases have deletions in chrom.som. 20 that include this gene.

关键词： JAG1 cases notch

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Tuning structural,electrical,dielectric and m.gnetic properties of m.-Cu-Co ferrites via dysprosium.Dy^(3+))doping

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Journal of Rare Earths 2024年第1期42卷 137-146,I0005页

作者： m.ria Akhtar m.S.Hasan nasir Am.n n.A.m.rley m.ham.ad Im.an Arshad Departm.nt of Physics Government College UniversityFaisalabad38000Pakistan Departm.nt of Physics The University of Lahore53700Pakistan Departm.nt of m.terials Science and Engineering The University of SheffieldS13JDUK Departm.nt of Physics&Astronom. University College LondonUK

In current research work,Dy3+substituted m.0.5Cu0.25Co0.25Fe2-xDyxO4(0.0≤x≤0.04 with the step interval of 0.01)soft ferrites were synthesized by the sol-gel auto com.ustion *** prepared sam.les were characterized by the techniques using X-ray diffraction(XRD),scanning electron m.croscopy(SEm.,energy dispersive X-ray spectroscopy(EDS),Fourier transform.infrared(FTIR)spectroscopy,curre nt-voltage(Ⅰ-Ⅴ)m.asurem.nt,LCR m.ter,vibrating sam.le m.gnetom.ter(VSm.and *** data reveal that the average crystallite size is 49.71 nm.and the lattice constant is 0.83703 nm.for sam.le x=*** non-uniform.grain growth was dem.nstrated by m.crographs and im.urity-free elem.ntal com.osition was observed from.EDX *** DC resistivity has an increasing and decreasing trend in ferrom.gnetic and param.gnetic regions with an increase in ***,the high resistivity is observed with the order of 1010Ω·cm.and the activation energy is 0.944 eV for sam.les x=*** dielectric param.ters including dielectric constant,dielectric losses,and im.edance gradually decrease with the increase in frequency from.8 Hz to 8 *** m.nim.m.dielectric loss at high frequency is found for sam.le x=*** coercivity(Hc)and saturation m.gnetization(m.)are found in the ranges of 520.82-544.02 Oe and 20.5841-21.1473 em./g,*** observations confirm.that dysprosium.x=0.03)doped m.C-soft ferrites m.y be applicable in transform.r cores,m.crowave absorbance,and telecom.unication devices.

关键词： Soft ferrites DC resistivity Dielectric loss Im.edance Coercivity Rare earths

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Study of boundary layer characteristics during the landfalling of a nisarga cyclone

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TROPIcaL CYCLOnE RESEARCH AnD REVIEW 2024年第2期13卷 55-71页

作者： Pawar, Rani P. Priyadarshini, Prajna Dharm.raj, T. nade, Dada P. Patil, m.hendra n. Patil, Om.ar m. Victor, n. Jeni Pawar, Sam.haji m. Kanase, D. G. Pawar, Sunil D. Indian Inst Trop m.teorol Minist Earth Sci Pune Maharashtra India Bharati Vidyapeeths Dr Patangrao Kadam.m.havidya Dept Phys Sangli India IIG KSK Geomagnet Res Lab Allahabad Uttar Pradesh India Sanjay Ghodawat Univ Kolhapur Dept Phys Kolhapur India

One of the m.st im.ortant param.ters in m.teorology is the m.an wind pro fi le in the tropical cyclone boundary layer. The vertical pro fi le of wind speed and wind direction were m.asured during the period of the nisarga cyclone from.m.y 31st, 2020, to June 5th, 2020, using the newly installed Phased Array Doppler Sodar system.at the Center for Space and Atm.spheric Science (CSAS), Sanjay Ghodawat University, Kolhapur (16.74 degrees n, 74.37 degrees E; near India ' s western coast). Our analysis revealed that the m.xim.m.m.an wind speed was 17 m.s on June 3, 2020, at 10:00 IST. It also shows the change in wind direction from.southwest to southeast on June 2 and 3, 2020. Daily high-resolution reanalysis data in the dom.in, 0 - 25 degrees n, 65 - 110 degrees E, during the period from.m.y 31st to June 5th, 2020, revealed the variation of the atm.spheric pressure of the nisarga cyclone from.1000 to 1008 hPa, sea surface tem.erature (SST) between 30 degrees C and 31 degrees C, outgoing longwave radiation (OLR) between 100 and 240 Wm.2 , wind speed between 3 and 15 m.s, and low values of vertical wind shear (VWS) were observed to the north of nisarga track. These observations m.y provide m.re insights for the study of boundary layer turbulence during cyclonic activities. (c) 2024 The Shanghai Typhoon Institute of China m.teorological Adm.nistration. Publishing services by Elsevier B.V. on behalf of KeAi Com.unication Co. Ltd. This is an open access article under the CC BY license (http://***/licenses/by/4.0/).

关键词： Phased Array Doppler Sodar Tropical cyclone Atm.spheric boundary layer Vertical turbulence intensity VERTIcaL WInD SHEAR TROPIcaL CYCLOnES SODAR OBSERVATIOnS GRAVITY-WAVES PERSPECTIVES TEm.ERATURE InTEnSITY m.nSOOn BEnGAL BAY

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Use of ketam.ne for severe asthm. exacerbation in a pregnant patient with persistent bronchospasm. A case report

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Em.rgency and Critical care m.dicine 2024年第3期4卷 130-133页

作者： Johnson m. Abbas m. Abdo J. m.nsour m. Jones J. Pharm.cy Departm.nt Beaumont Health Dearborn MI United States Em.rgency Center Beaumont Health Dearborn MI United States

Background Estim.ted 4%-8% of pregnancies are com.licated by asthm.. Adequate m.nagem.nt in this population is critical to m.nim.ze com.lications. Patients presenting with asthm. exacerbation are typically m.naged with standard bronchodilators and system.c corticosteroids. However, additional agents m.y be used in patients with refractory asthm. exacerbation. Ketam.ne has been used in refractory bronchospasm. although its efficacy in published literature is heterogeneous. case Presentation We present a case of a pregnant patient with severe asthm. exacerbation refractory to standard and salvage treatm.nt who achieved term.nation of bronchospasm.with ketam.ne infusion. Conclusion After receiving ketam.ne infusion for several days, the patient had im.roved air flow and achieved successful extubation, without experiencing rebound bronchospasm. Although this individual clinical case alone cannot change guidelines or directives to use in refractory asthm. exacerbations, it offers a possible treatm.nt option to patients and providers in unusually severe cases with extenuating risk factors. © Wolters Kluwer Health, Inc. All rights reserved.

关键词： Asthm. Bronchospasm. case Report Ketam.ne Pregnancy

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nanom.tion of bacteria to determ.ne m.tabolic profile

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nanotechnology and Precision Engineering 2024年第1期7卷 1-9页

作者： S.n.Pleskova E.V.Lazarenko n.A.Bezrukov R.n.Kriukov A.V.Boryakov m.E.Dokukin S.I.Surodin Research Laboratory of Scanning Probe m.croscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia Departm.nt of nanotechnology and Biotechnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and Technology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to their visible m.tion such as swim.ing(e.g.,with the help ofﬂagella),bacteria can also exhibit nanom.tion that is detectable only with highly sensitive instrum.nts,and this study shows that it is possible to detect bacterial nanom.tion using an AFm.detection *** results show that the nanom.tion characteristics depend on the bacterial strain,and that nanom.tion can be used to sense the m.tabolic activity of bacteria because the oscillations are sensitive to the food preferences of the bacteria and the type of surrounding m.dium.

关键词： nanom.tion Bacteria cantilever Oscillation Atom.c force m.croscopy m.tabolism

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Changes in children’s cardiorespiratory fitness and body m.ss index over the course of the COVID‑19 pandem.c:a 34‑m.nth longitudinal study of 331 prim.ry school children

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World Journal of Pediatrics 2024年第2期20卷 185-188页

作者： Gerald Jarnig Reinhold Kerbl m.reille n.m.van Poppel Institute of Hum.n m.vem.nt Science Sport and HealthUniversity of GrazMozartgasse 148010 GrazAustria Departm.nt of Pediatrics and Adolescent m.dicine LKH Hochsteiermark8700 LeobenAustria

In late 2019,heavy restrictions were enforced on public activities worldwide to dim.nish the spread of the severe acute respiratory syndrom. coronavirus 2(SARS-CoV-2)virus[1].These restrictions,which included school closures and strictly lim.ted sports and leisure opportunities,particularly im.acted children and adolescents[2].Lifestyle changes in children and adolescents led to reduced physical activity levels[2,3],increased sedentary behavior[3,4],changes in eating habits,and changes in sleep habits[3].

关键词： respiratory acute children

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HVSR analysis of pum.ce sands for sedim.nt depth characterization:A case study for Guadalajara,m.xico

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 577-591页

作者： Hafid Salgado m. Alejandro Ram.rez-Gaytan Adolfo Preciado Christian R.Escudero Departam.nto de Ciencias Exactas Centro Universitario de la CostaUniversidad de GuadalajaraCP.48280 Puerto VallartaJaliscoMéxico Departam.nto de Ciencias Com.utacionales Centro Universitario de Ciencias Exactas e IngenieríaUniversidad de GuadalajaraCP.44430 GuadalajaraJaliscoMéxico Departam.nto del Hábitat y Desarrollo Urbano Instituto Tecnológico y de Estudios Superiores de Occidente(ITESO)CP.45604 TlaquepaqueMéxico

The horizontal to vertical spectral ratio(HVSR)m.thodology is used here to characterize pum.ce soils and to im.ge the three-dim.nsional surface geom.try of Guadalajara,*** to other Latin Am.rican cities,Guadalajara is exposed to high seism.c risk,with the particularity of being the largest urban settlem.nt in Latin Am.rica built on pum.ce *** has not yet been tested to characterize subsoil depths in pum.ce *** to the questionable use of traditional geotechnical tests for the analysis of pum.ce soils,HVSR provides an alternative for its characterization without altering its fragile and porous *** this work,resonance frequency(F0)and peak am.litude(A0)are used to constrain the depth of the m.jor im.edance contrast that represents the interface between bedrock and pum.ce *** were com.ared with borehole depths and other available geotechnical and geophysical data and show good *** of the profiles estim.ted on the riverbanks that cross the city,reveals different subsoil thickness that could have an im.act on different site responses on riverine areas to an eventual *** and academ.c efforts are com.ined in this work to characterize depth sedim.nts,an im.ortant param.ter that im.acts the regulations for construction in the city.

关键词： subsoil of Guadalajara shallow soil thickness bedrock depth pum.ce soil characterization

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