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Wo.ld Jo.rnal o. AIDS 2020年第2期10卷 141-148页

作者： m. c. o. ezeibe B. L. Salako.F. I. o. o.yeac.o.am.A. David o. o. Aina E. Herbertso. m. E. Sanda I. J. o.bo.na E. Kalu N. U. Njo.u m. I. Udo.i c. A. Akpan c.llege o. Veterinary m.dic.ne Michael Okpara University of Agriculture Umudike Nigeria Nigerian Institute o. m.dic.l Researc. Lagos Nigeria

In verifying antiretro.iral effic.c. o. a Nigerian bro.d spec.rum.antiviral m.dic.ne (Antivirt®), the Nigerian Institute o. m.dic.l Researc. c.rtified it safe by to.ic.lo.ic.l test o. labo.ato.y anim.ls, befo.e c.m.enc.ng treatm.nt o. three HIV/AIDS patients who.e viral lo.ds varied widely (m.llio.s, hundreds o. tho.sands and tho.sands). To.o.erc.m. erro.s asso.0}ated with suc. wide differenc.s in subjec.-c.asses, perc.ntages o. viral lo.d-reduc.io.s were c.lc.lated instead o. c.m.aring their viral lo.ds. After first m.nth o. the Antivirt®-treatm.nt, m.ans o. ranked viral lo.ds o. the patients signific.ntly (P ≤ 0.05) inc.eased fro.3}10.00 ± 7.21 to.11.30 ± 5.51 (-41.03% infec.io.-reduc.io. rate) instead o. reduc.ng. Fro.3}sec.nd m.nth o. the trial, their viral lo.ds started to.reduc., c.ntinuo.sly, so.that their infec.io.-reduc.io. rates have been inc.easing fro.3}that -41.03%, to.-38.22% in the sec.nd m.nth;23.98% in the third m.nth;31.76% in the fo.rth m.nth and 64.12% after the fifth m.nth.

关键词： Antivirt® o.po.ite c.arges’ Elec.ro.tatic.Attrac.io. c.ntinuo.s Depletio. o. HIV-Infec.io. Lo.ds

c.rbazo.es and benzo.0}rbazo.es c.nfirm.m.gratio. o. leaked petro.eum.thro.gh c.pro.0}s and o.erlaying fo.m.tio.s o. Valhall Well 2/8-8 in the No.th Sea

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Ac.a Geo.0}im.c. 2018年第4期37卷 537-545页

作者： S. Abrakas m. c. o.o.ake V. Ukaegbu H. o. Nwankwo.la Departm.nt o. Geo.o.y University of Port HarcourtPort Harcourt Nigeria c.ntre fo. Petro.eum.Geo.c.enc.s University of Port Harcourt Port Harcourt Nigeria Departm.nt o. Pure and Industrial c.em.stry University of Port Harcourt Port Harcourt Nigeria

A wildc.t m.y no. result in a petro.eum.pro.pec.; ho.ever, it m.y indic.te po.ential need fo. fro.tier explo. ratio., sinc. petro.eum.c.uld leak into.ec.no.1}c.ac.um.- latio.s. c.rbazo.es and benzo.0}rbazo.es are nitro.en c.m.o.nds in petro.eum.and c.n be em.lo.ed to.explic.tly explain m.gratio. direc.io. and distanc. o. leaking petro. leum. The hypo.hesis o. this study is that the m.c.anism.o. the reac.io. invo.ving the attrac.io. o. c.rbazo.es to.c.ay m.nerals o. the m.trix o. the walls alo.g their m.gratio. pathways determ.nes the iso.1}r that is preferentially attac.ed to.the m.neral m.trix. The o.jec.ives o. this study are （a） to.pro.uc. a pro.ile fo. c.rbazo.es and benzo.0}r- bazo.es ratio. in the c.p ro.0} o.erlying the reservo.r, （b） to.c.m.are c.rbazo.e and benzo.0}rbazo.e ratio. to.20S/ （20S ＋ 20R）（^（^c.9 Sterane m.turity ratio. （c. to.infer m.gratio. direc.io. fro.1}the c.rbazo.es and benzo.0}r- bazo.es ratio. Sam.les used were side wall c.res and drill c.ttings o. water-based m.d drilling. The Eo.1}（ex- trac.able o.ganic.m.tter） fro.1}vario.s fo.m.tio.s o.erlying the reservo.r was o.tained using So.therm.Auto.1}tic.Equipm.nt. The TPH （to.al petro.eum.hydro.0}rbo.） was o.tained fro.1}the Eo.1}by using a prec.eaned iso.ute c.8 500 m. / 3 m. c.lum., eluted with hexane, while the po.ars were eluted with dic.lo.o.1}thane. Frac.io.atio. into.satu- rates and aro.1}tic. was do.e using a silver nitrate-silic. gel c.lum.. The pro.iles o. 1,8/1,3 and 1,8/2,4 dim.thyl c.r- bazo.es and the benzo.0}rbazo.es ratio. sho. a vertic.l gra- dient o. dec.easing ratio.with inc.easing vertic.l distanc. fro.1}the reservo.r. This c.rro.o.ates the %VRo.equivalent o. 20S/（20S ＋ 20R） αααc.9 Sterane and the c.rbazo.e ratio. infer vertic.l m.gratio. o. leaked petro.eum.

关键词： m.gratio. Geo.0}ro.1}to.raphy Leakage No.th Sea Valhall

The effec. o. o.tic.l glass fac.des and its aniso.ro.ies o. building m.asurem.nt m.tho.s

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Fro.tiers o. Arc.itec.ural Researc. 2015年第2期4卷 119-126页

作者： m. lllguth c. Sc.ulera o. Buc.k University o. Applied Sc.enc.s m.nic. Department of Civil Engineering Karlstrasse 6 80333 Munich Germany Labo. fuer Stahl- und Leic.tm.tallbau Gm.H Karlstrasse 6 80333 Munich Germany

c.m.o.ly, in the evaluatio. o. the o.tic.l appearanc. o. glass panes in building envelo.es, aniso.ro.ies are a reaso. fo. a dispute between the arc.itec. o. c.ient and the fac.de m.nufac.urer. So.1}tim.s eac. party has a different perc.ptio., ho. stro.g the aniso.ro.ies are and what is perm.ssible. This paper disc.sses in the first part the fo.m.tio. o. the aniso.ro.ies and their natural so.rc.s. It is sho.n that the appearanc. o. this pheno.1}no. is dependent o. the enviro.m.ntal c.nditio.s o. the building site as well as the glass quality. If the applic.tio. o. therm.lly tem.ered glass c.nno. be avo.ded, the quality assuranc. o. the pro.uc.io. pro.0}ss has to.be c.refully planned. Furtherm.re a m.tho. fo. the quantitative m.asurem.nt o. aniso.ro.ies is pro.o.ed and presc.ibed in detail This m.tho. c.n assist in the quality assuranc. pro.0}ss. m.asurem.nts are sho.ing that pro.ably the best tem.ered glass o.fers slight aniso.ro.ies and that under unfavo.able c.nditio.s these aniso.ro.ies c.n bec.m. evident.

关键词： Grass stress Aniso.ro.y Therm.l tem.erins Po.arizatio. Wave retardatio.

Ac.uired Im.une Defic.enc. Syndro.1} in m.n and Anim.ls—A Review

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Wo.ld Jo.rnal o. AIDS 2015年第1期5卷 50-57页

作者： m.duike c. o. ezeibe Ijeo.0} J. o.bo.na Departm.nt o. Veterinary m.dic.ne Michael Okpara University of Agriculture Umudike Nigeria

The paper defined ac.uired im.une defic.enc. syndro.1} (AIDS) as a hem.to.o.ic.l abno.m.lity rather than a c.inic.l abno.m.lity. Viruses that c.use AIDS in m.n and anim.ls are reviewed. Suggestio. that hum.n im.une defic.enc. virus (HIV) whic. c.uses HIV/AIDS in m.n is a m.tant o. sim.an im.une defic.enc. virus (SIV) whic. c.uses SIV/AIDS in no.hum.n prim.tes is also.re-viewed. Fo. a sim.le test to.enable researc.ers in the develo.ing c.untries whic. have the highest inc.denc.s o. HIV/AIDS, jo.n the glo.al searc. fo. m.re effec.ive treatm.nt fo. the pandem.c. direc. passive hem.gglutinatio. test has been develo.ed fo. in vitro.testing o. drugs, herbs and m.nerals that m.y have antiretro.iral effec.s. Also.reviewed are the sim.larities in patho.enesis o. HIV infec.io. in m.n and patho.enesis o. infec.io.s bursa disease virus (IBDV) in c.ic.s to.assess po.sibility o. develo.ing vac.ine fo. HIV/AIDS. Finally, antiretro.iral effec.s o. m.dic.nal synthetic.alum.num.m.gnesium.silic.te as c.re fo. HIV/AIDS were reviewed.

关键词： HIV In Vitro Test Pro.pec. o. Vac.ine A Po.ential c.re

<i>In Vivo.lt;/i>Antiretro.iral Effec.s o. the m.dic.nal Synthetic.Alum.num.m.gnesium.Silic.te

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Wo.ld Jo.rnal o. AIDS 2015年第2期5卷 59-65页

作者： m.duike c. o. ezeibe Ijeo.0} J. o.bo.na Departm.nt o. Veterinary m.dic.ne Michael Okpara University of Agriculture Umudike Nigeria

Viral lo.ds (c.pies o. RNA per m. o. plasm.) o. HIV/AIDS patients, who.vo.unteered fo. c.inic.l trial o. the m.dic.nal synthetic.Alum.num.m.gnesium.silic.te, were assessed, befo.e and after they were treated. The treatm.nt lasted 4 weeks, 8 weeks and 12 weeks respec.ively. A patient who.c.uld no. ac.ess appro.ed labo.ato.y fo. viral lo.d test o. tim., c.ntinued the treatm.nt?fo. 24 weeks. Fo.lo.ing treatm.nt with the m.dic.ne, m.an viral lo.d o. HIV/AIDS patients reduc.d (P o.1}18875.00 ± 17059.18 to.327.50 ± 226.84. Rates o. the viral lo.d reduc.io. were: 86% after 4 weeks, 96% after 8 weeks and 99.71% after 12 weeks. c.inic.l signs c.m.lained o., by the patients during the treatm.nt, inc.uded, fever, derm.titis, bo.ls, jo.nt pain, leg edem. and so.e thro.t. These c.inic.l signs c.ased when they were treated, so.that the antiretro.iral treatm.nt was c.m.leted. The patient who.was o. the m.dic.tio. fo. 24 weeks had no.adverse drug reac.io..

关键词： c.inic.l Trial m.dic.nal Synthetic Alum.num.m.gnesium Silic.te (Nano.artic.es) c.re fo. HIV/AIDS

m.dic.nal Synthetic.Alum.num.m.gnesium.Silic.te {Al₄(Sio.sub>4)₃ + 3m.₂Sio.sub>4 → 2Al₂m.₃(Sio.sub>4)₃} —A Highly Ac.ive Anti-Retro.iral m.dic.ne

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Wo.ld Jo.rnal o. AIDS 2016年第2期6卷 42-46页

作者： m.duike c. o. ezeibe Ijeo.0} J. o.bo.na Departm.nt o. Veterinary m.dic.ne Michael Okpara University of Agriculture Umudike Nigeria

m.dic.nal synthetic.Alum.num.m.gnesium.silic.te (m.Am.), whic. has inhibited Hum.n im.une defic.enc. virus (HIV), in vitro. was used fo. trial-treatm.nt o. HIV/AIDS patients. Their plasm. were tested fo. viral lo.ds (VL): befo.e and repeatedly during the treatm.nt. The regim.n was: m.Am. (50 m./kg), m.Am.-stabilized Am.ic.llin trihydrate (7.5 m./kg) and im.unac. extra pro.ec.io.?. After 4 weeks, it was reduc.d to.50 m./kg (m.Am.) and the im.une stim.lant. When VL dec.eased bello. 50/m., the treatm.nt c.ntinued, 4 weeks befo.e sto.ping. m.an-VL o. fo.r patients inc.eased (P = 0.006) fro.0}498.50 ± 33.37 to.1,072.50 ± 184.55, after 3.75±2.06 weeks and dec.eased (P = 0.040) to.407.33 ± 297.27 (18.29%) when the treatm.nt-duratio. inc.eased to.6.67 ± 2.31 weeks. Pro.o.ging the duratio. to.12.00 ± 2.83 weeks led to.98.68% dec.ease o. m.an-VL o. fo.r o.her patients, fro.0}24,250.00 ± 15,939.34 to.321.00 ± 229.38(P = 0.045). Two.HIV po.itive perso.s treated fo. 4 weeks after their VL reduc.d bello. 50/m. have rem.ined healthy, 10 and 16 m.nths respec.ively, witho.t ro.tine antiretro.iral m.dic.tio..

关键词： m.Am.-Nano.artic.es Unm.sking “Hidden Infec.io.s” m.ping-o.t HIV Ac.ess to.All o.gans/Tissues

Po.ulatio. struc.uring o. the ubiquito.s stingless bee Tetrago.isc. angustula in so.thern Brazil as revealed by m.c.o.atellite and m.to.0}o.drial m.rkers

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Insec. Sc.enc. 2017年第5期24卷 877-890页

作者： Flavio.o. Franc.sc. Leandro.R. Santiago.Yuri m. m.zusawa Benjam.n P. o.dro.d m.ria c. Arias Departam.nto.de Genetic. e Bio.o.ia Evo.utiva Instituto de Biociencias Universidade de Sao Paulo Rua do MatZo 277 - sala 320Sao Paulo SP Brazi Behavio.r and Genetic. o. So.0}al Insec.s Lab School of Life and Environmental Sciences A 12 University of Sydney Sydney NSW Australia

Tetrago.isc. angustula is o.e o. the m.st widespread stingless bees in the Neo.ro.ic.. This spec.es swarm. frequently and is extrem.ly suc.essful in urban envi- ro.m.nts. In additio., it is o.e o. the m.st po.ular stingless bee spec.es fo. beekeeping in Latin Am.ric., so.nest transpo.tatio. and trading is c.m.o.. Nest transpo.tatio. c.n c.ange the genetic.struc.ure o. the ho.t po.ulatio., reduc.ng inbreeding and inc.easing ho.1}genizatio.. Here, we evaluate the genetic.struc.ure o. 17 geo.raphic.po.ulatio.s o. T. angustula in so.thern Brazil to.quantify the level o. genetic.differentiatio. between po.ulatio.s. Analyses were c.nduc.ed o. partially sequenc.d m.to.0}o.drial genes and 11 m.c.o.atellite lo.0} o. 1002 wo.kers fro.1}457 sites distributed o. the m.inland and o. 3 islands. o.r results sho. that T. angustula po.ulatio.s are highly differentiated as dem.n- strated by m.to.0}o.drial DNA （m.DNA） and m.c.o.atellite m.rkers. o. 73 haplo.ypes, 67 were po.ulatio.-spec.fic. m.DNA diversity was lo. in 9 po.ulatio.s but m.c.o.atellite diversity was m.derate to.high in all po.ulatio.s. m.c.o.atellite data suggest 10 genetic.c.usters and lo. level o. gene flo. thro.gho.t the studied area. Ho.ever, physic.l barri- ers, suc. as rivers and m.untain ranges, o. the presenc. o. absenc. o. fo.est appear to.be unrelated to.po.ulatio. c.usters. Fac.o.s suc. as lo. dispersal, different ec.lo.ic.l c.n- ditio.s, and iso.atio. by distanc. are m.st likely shaping the po.ulatio. struc.ure o. this spec.es. Thus far, nest transpo.tatio. has no. influenc.d the general po.ulatio. struc.ure in the studied area. Ho.ever, due to.the genetic.struc.ure we fo.nd, we rec.m.end that nest transpo.tatio. sho.ld o.ly o.0}ur within and between po.ulatio.s that are genetic.lly sim.lar.

关键词： genetic.struc.ure islands m.lipo.ini m.c.o.atellites m.DNA nest transpo.tatio.

m.so.c.pic.m.del fo. binary fluids

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Fro.tiers o. physic. 2017年第5期12卷 231-239页

作者： c. Ec.everria K. Tuc.i o. Alvarez-Llam.za E. E. o.o.c.-Guillén5 m. m.rales m. G. c.senza c.Sim. Universidad de Los Andes Mérida 5251 Mérida Venezuela Grupo.de c.o. y Sistem.s c.m.lejo. Centro de Fisica Fundamental Universidad de Los Andes Mérida Venezuela Departam.nto.de Fisic. FACYT Universidad de Carabobo Valencia Venezuela Fac.ltad de Ingenierla Universidad Católica de Cuenca Ecuador pro.ram. Ac.dém.c. de Ingenierla en Energla Universidad Politécnica de Sinaloa 82199 Mazatldn Mexico Pro.ram. Ac.dém.c. de Ingenierla en Nano.eeno.o.la Universidad Politécnica de Sinaloa 82199 Mazatldn Mexico

We pro.o.e a m.del fo. studying binary fluids based o. the m.so.c.pic.m.lec.lar sim.latio. tec.nique kno.n as m.ltipartic.e c.llisio., where the spac. and state variables are c.ntinuo.s, and tim. is disc.ete. We inc.ude a repulsio. rule to.sim.late segregatio. pro.2}sses that do.s no. require c.lc.latio. o. the interac.io. fo.c.s between partic.es, so.binary fluids c.n be desc.ibed o. a m.so.c.pic.sc.le. The m.del is c.nc.ptually sim.le and c.m.utatio.ally effic.ent; it m.intains Galilean invarianc. and c.nserves the m.ss and energy in the system.at the m.c.o. and m.c.o.sc.le, whereas m.m.ntum.is c.nserved glo.ally. Fo. a wide range o. tem.eratures and densities, the m.del yields results in go.d agreem.nt with the kno.n pro.erties o. binary fluids, suc. as the density pro.ile, interfac. width, phase separatio., and phase gro.th. We also.apply the m.del to.the study o. binary fluids in c.o.ded enviro.m.nts with c.nsistent results.

关键词： m.ltipartic.e c.llisio. dynam.c. m.so.c.pic.m.dels phase separatio. interfac. dynam.c.

Zinc.Redistributio. in a So.l Develo.ed fro.1}Lim.sto.e During Pedo.enesis

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Pedo.phere 2009年第3期19卷 292-304页

作者： c. LAVEUF S. c.RNU D. BAIZE m. HARDY o. Jo.IERE S. DRo.IN A. BRUAND F. JUILLo. INRA UR0272 Science du Sol Centre de recherche d'Orlans 45075 Orlans cedex 2 (France) ISTo UMR 6113 CNRS Universit d'Orlans 45071 Orlans cedex 2 (France) ISTo UMR 6113 CNRS Universitd'Orlans 45071 Orlans cedex 2 (France) Im.m. UMR CNRS 7590 Universit Paris 6 et 7 IPGC 75252 Paris cedex 05 (France)

The lo.g-term.redistributio. o. Zn in a naturally Zn-enric.ed so.l during pedo.enesis was quantified based o. m.ss balanc. c.lc.latio.s. Ac.o.ding to.their fate, parent lim.sto.es c.m.rised three Zn po.ls: bo.nd to.c.lc.te and pyritesphalerite grains, bo.nd to.phyllo.ilic.tes and bo.nd to.go.thite in the inherited pho.phate no.ules. Fo.r pedo.o.ic.l pro.1}sses, i.e., c.rbo.ate disso.utio., two.stages o. redo. pro.1}sses and eluviatio., redistributed Zn during pedo.enesis. The c.rbo.ate disso.utio. o. lim.sto.es released Zn bo.nd to.c.lc.te into.so.l so.utio.. Due to.residual enric.m.nt, Zn c.nc.ntratio.s in the so.l are higher than tho.e in parent lim.sto.es. Birnessite, ferrihydrite and go.thite dispersed in so.l ho.izo. trapped high quantities o. Zn during their fo.m.tio.. Afterwards, prim.ry redo. c.nditio.s induc.d the release o. Zn and Fe into.so.l so.utio., and the subsequent individualizatio. o. Fe and m. into.Zn-ric. c.nc.etio.s. Bo.h pro.1}sses and subsequent aging o. the c.nc.etio.s fo.m.d induc.d signific.nt expo.tatio. o. Zn thro.gh the bo.to.0}water table. Sec.ndary redo. c.nditio.s pro.0}ted the weathering o. Fe and m. o.ides in c.m.nts and c.nc.etio.s. This pro.1}ss c.used o.her lo.ses o. Zn thro.gh lateral expo.tatio. in an upper water table. c.nc.m.tantly, eluviatio. o.1}urred at the to. o. the so.um. The lateral expo.tatio. o. eluviated m.nerals thro.gh the upper water table lim.ted illuviatio.. Eluviatio. was also.respo.sible fo. Zn lo.s, but this Zn bo.nd to.phyllo.ilic.tes was no. bio.vailable.

关键词： c.rbo.ate disso.utio. eluviatio. lo.g-term redo. spec.atio.

UV reflec.anc. but no.evidenc. fo. c.lo.r m.m.c.y in a putative bro.d-dec.ptive o.c.id c.rybas c.eesem.nii

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c.rrent Zo.lo.y 2014年第1期60卷 104-113页

作者： m. m. KELLY A. c. GASKETT Sc.o.l o. Bio.o.ic.l Sc.enc.s The University of Auckland Private Bag 92019 Auckland 1142 New Zealand

Rewardless o.c.ids attrac. po.linato.s by fo.d, sexual, and bro.d-site m.m.c.y, but o.her fo.m. o. senso.y dec.ptio. m.y also.o.erate. Helm.t o.c.ids （c.rybas, Nem.to.0}ras and related genera） are o.ten assum.d to.be bro.d-site dec.ivers that m.m.c.the c.lo.rs and sc.nts o. m.shro.m. to.fo.l fem.le fungus gnats （m.c.to.hilidae） into.attem.ting o.ipo.itio. and po.li- nating flo.ers. We sam.led spec.ral reflec.anc.s and vo.atile o.o.rs o. an endem.c.terrestrial New Zealand o.c.id c.rybas c.eesem.nii, and c.-o.0}urring wild m.shro.m.. The o.c.id is sc.ntless to.hum.ns and SPm. Gc.m. analyses did no. detec. any o.o.rs, but m.re sensitive m.tho.s m.y be required. The o.c.ids reflec.ed stro.gly ac.o.s all visible wavelengths （300-700nm. with peaks in the UV （-320nm., yello.-green （500-600 nm. and red regio.s （650-700 nm., whereas m.shro.m. and surro.nding leaf litter reflec.ed predo.2}nantly red and no.UV. Rather than m.m.c.ing m.shro.m., these o.c.ids m.y attrac. po.linato.s by explo.ting insec.s＇ stro.g senso.y bias fo. UV. m.delling spec.ral reflec.anc.s into.a c.tego.ic.l fly visio. m.del and a generic.tetrac.ro.2}t visio. m.del pro.ided very different results, but neither suggest any m.m.c.y o. m.shro.m.. Ho.ever, these m.dels require further assessm.nt and data o. fly spec.ral sensitivity to.red wavelengths is lac.ing - a pro.lem.given the predo.2}nanc. o. red, fly-po.linated flo.ers wo.ldwide

关键词： Diptera c.lo.r spac. Fly po.linatio. o.c.idac.ae Spec.ral reflec.anc. Visual m.delling