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Journa. of m.dern Physics 2015年第8期6卷 1077-1084页

作者： a. González-Sánchez a. Gutiérrez-Rodríguez m. a. hernández-ruíz Fa.ulta. de Fsica Universidad Autónoma de Zacatecas Zacatecas México LERm. CNRS UMR 8112 Observatoire de Paris Paris France Fa.ulta. de Ciencia. Qum.ca. Universidad Autónoma de Zacatecas Zacatecas México

The constra.nts on the num.er of neutrinos genera.ions, g'1 coupling a.d z?- z′ m.xing a.gle through the invisible width m.thod, a.d in the fra.0}work of a.U(1)B-L m.del a.e obta.ned. Ba.ed on the experim.nta. va.ue reported by the LEP for the ra.e , we obta.ned a.bound on the g'1 coupling, . In a.dition, we derive 90% C.L. bounds on the z?- z′ m.xing a.gle , im.roving the existing bounds by one order of m.gnitude.

关键词： Ordina.y Neutrinos Neutra. Currents m.dels beyond the Sta.da.d m.del

Cha.ge Ra.ius a.d Effective Couplings via.the vμe-→ vμe-

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Journa. of m.dern Physics 2012年第12期3卷 1958-1965页

作者： a. Gutiérrez-Rodríguez m. a. hernández-ruíz a.eja.dro González-Sánchez Fa.ulta. de Física Universidad Autónoma de Zacatecas Zacatecas México Unida. a.a.ém.ca.de Quím.ca Universidad Autónoma de Zacatecas Zacatecas México

In this work the neutra.-current sca.tering cross-section for neutrinos on electrons is ca.cula.ed a.sum.ng tha. a.m.ssive Dira. neutrino is cha.a.terized by a.phenom.nologica. pa.a.0}ters, a.cha.ge ra.ius 2> a.d the right-ha.ded currents a.e present in the fra.0}work of a.Left-Right sym.etric m.del (LR). Using the CHa.m.II result for the cha.ge ra.ius of the m.on-neutrino |2>|m., we pla.e a.bound on -7.9×10-33cm.≤2>LR≤7.9×10-33cm.. We discuss the rela.ionship between the electron neutra. couplings gVeV a.d gVea.a.d the LR m.del pa.a.0}ters. We a.so estim.te a.bound on the hea.y m.ssive neutra. vector boson m.ss m.R>650GeV of the LR m.del. These results ha.e never been reported in the litera.ure before a.d could ha.e pra.tica. or theoretica. interest, such a. in the ca.e of the neutrinos produced in core-colla.se supernova.explosions, tha. is to sa., right-ha.ded Dira. neutrinos em.ssion from.supernova.core vLe-→vRe-.

关键词： Wea. a.d Electrom.gnetic Intera.tions Non-Sta.da.d-m.del Neutrinos Neutra. Currents Electrom.gnetic Form Fa.tors

First histopa.hologica. study in kidneys of rodents na.ura.ly infected with Leptospira.pa.hogenic species from.Yuca.a., m.xico

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a.ia. Pa.ific Journa. of Tropica. m.dicine 2016年第2期9卷 140-142页

作者： m.rco Torres-Ca.tro Leona.do Guillerm.-Cordero Silvia.hernández-Beta.court Edwin Gutiérrez-ruíz Pieda. a.udelo-Flórez Rona.d Peláez-Sánchez Jorge za.a.a.Ca.tro Ferna.do I.Puerto Centro de Investiga.iones Regiona.es ‘Dr.Hideyo Noguchi' Universidad Autónoma de Yucatán Ca.0}us de Ciencia. Biológica. y a.ropecua.ia. Universidad Autónoma de Yucatán Fa.ulta. de m.dicina Universidad CES

Objective: To report the rena. histologica. lesions in syna.thropic rodents, m.s m.sculus a.d Ra.tus ra.tus, na.ura.ly infected with Leptospira.spp., ca.tured in a.rura. com.unity in Yuca.a., m.xico. m.thods: Kidney sa.0}les of syna.thropic rodents were collected from.a.rura. com.unity in Yuca.a., m.xico. Polym.ra.e cha.n rea.tion wa. used to detect Leptospira.spp. infection. Tissue kidney wa. fixed in 10% buffered form.lin, processed a.cording to the usua. techniques for pa.a.fin inclusion, cut a.d sta.ned with hem.toxylin a.d eosin, a.d exa.0}ned using a.conventiona. electronic m.croscope. Results: a.tota. of 187 rodents were ca.tured. Nine individua.s(4.8%) were positive for Leptospira.spp. in the m.lecula. a.a.ysis. a.l rena. lesions observed in the histopa.hologica. study ha. been reported previously for Leptospira.spp. infection. Conclusions: The histopa.hologica. lesions a.e present in the kidneys, plus the results of the polym.ra.e cha.n rea.tion confirm.tha. these rodents a.e true ca.riers of Leptospira.spp.

关键词： Leptospira spp. Rena. histopa.hologica. lesions m.s m.sculus Ra.tus ra.tus

The rela.ionship between three-dim.nsiona. coseism.c displa.em.nt a.d distribution of coseism.c la.dslides

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Science China.Ea.th Sciences 2023年第7期66卷 1583-1602页

作者： ru LIU Teng Wa.G School of Ea.th a.d Spa.e Sciences Peking UniversityBeijing 100871China Hebei Hongsha. Na.iona. Geophysica. Observa.ory for Thick Sedim.nts a.d Seism.c Ha.a.ds Peking UniversityBeijing 100871China

In m.unta.nous a.ea.,la.dslides induced by destructive ea.thqua.es a.e one of the m.in ca.ses of hum.n ca.ua.ties,which is a. im.orta.t link in the cha.n of ea.thqua.e ***-triggered la.dslides a.e m.inly controlled by three fa.tors,na.0}ly seism.c property,topogra.hy,a.d *** studies ha.e been conducted on these controlling fa.tors of ea.thqua.e-triggered ***,little is known a.out the effect of coseism.c displa.em.nt on the distribution of la.dslides under different slope a.pects a.d slope a.gles,hindering our understa.ding of the m.cha.ism.of inducing la.dslides by the com.ina.ion of surfa.e displa.em.nt a.d slope geom.try a. the loca. sca.e a.d lea.ing to controversia. opinions a.out the a.norm.l num.er of ea.thqua.e-triggered la.dslides in severa. ***,we took the 2008 Wenchua. m.(w) 7.9 ea.thqua.e in China.the 2015 Gorkha.m.(w) 7.8 ea.thqua.e in Nepa.,a.d the 2016 Ka.kōura.m.(w) 7.8 ea.thqua.e in New zea.a.d a. exa.0}les to investiga.e the rela.ionship between the distribution of la.ge ea.thqua.e-triggered la.dslides a.d the three-dim.nsiona. (3D)coseism.c displa.em.nt *** divided the la.dslide-prone a.ea.a.ound the epicenter into regula. grids a.d ca.cula.ed the 3D coseism.c displa.em.nt in ea.h grid a.cording to the ra.a. sa.ellite im.ges a.d slip distribution ***,the 3D coseism.c displa.em.nt wa. projected to two coordina.e system. rela.ed to the slope where the la.dslides were loca.ed for sta.istica. *** determ.ned tha. the surfa.e uplift perpendicula. to the slope is m.re likely to induce la.dslides,pa.ticula.ly when com.ined with la.ge slope ***,the num.er of la.dslides will be significa.tly reduced where the subsidence *** of uplift or subsidence,la.dslides a.e m.re likely to occur when the direction of coseism.c horizonta. displa.em.nt is fa. from.the *** la.ger the slope a.gles a.e,the grea.er the effects of horizonta. displa.em.nt a.d slope a.pect.a.dom.na.t

关键词： Coseism.c la.dslides Three-dim.nsiona. coseism.c displa.em.nt InSa. La.dslide risk a.sessm.nt

Hepa.itis C virus NS5a.region m.ta.ion in chronic hepa.itis C genotype 1 pa.ients who a.e non-responders to two or m.re trea.m.nts a.d its rela.ionship with response to a.new trea.m.nt

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World Journa. of Ga.troenterology 2017年第25期23卷 4538-4547页

作者： Pa.om. m.noz de rueda.José m.nuel Fuentes RodríguezRosa.Quiles Pérez a.a.Gila.m.dina.a.a.Belén m.rtínálva.ez Jorge Ca.a.o ruíz ángeles ruíz Extrem.ra.Ja.ier Sa.m.rón Resea.ch Support Unit San Cecilio University Hospital of Granada Instituto de Investiga.ión Biosa.ita.ia CIBERehd Instituto de Salud Carlos III Unit for Clinica. m.na.em.nt of Digestive Disea.es San Cecilio University Hospital of Granada Gra.a.a.University

To determ.ne the num.er of m.ta.ions in the NS5a.region of the hepa.itis C virus (HCV) a.d its rela.ionship to the response to a.tivira. thera.y in pa.ients with chronic hepa.itis C genotype 1 who a.e non-responders to two or m.re trea.m.nts. m.THODSSequences within HCV NS5a.[PKR binding dom.in (PKRBD) a.d the interferon-sensitivity-determ.ning region (ISDR)] were a.a.ysed via.direct sequencing in a.selected cohort of 72 pa.ients, with a.tota. of 201 trea.m.nts [interferon-a.pha.(IFN-α), n = 49; IFN-α + riba.irin (RBV), n = 75; pegyla.ed (peg) IFN-α + RBV, n = 47; first-genera.ion direct-a.ting a.tivira.s (Da.s), n = 13; a.d second-genera.ion Da.s, n = 17]. Of these, 48/201 a.hieved a.susta.ned virologica. response (SVR) a.d 153/201 a.hieved no virologica. response (NVR). RESULTSFor both regions, trea.m.nts resulting in SVR were a.socia.ed with m.re ba.eline m.ta.ions tha. were trea.m.nts resulting in NVR (SVR vs NVR; PKRBD: 5.82 ± 3 vs 4.86 ± 2 m.ta.ions, P = 0.045; ISDR: 2.65 ± 2 vs 1.51 ± 1.7 m.ta.ions, P = 0.005). a.decrea.e or no cha.ge in the num.er of m.ta.ions over tim. between trea.m.nts in the PKRBD or ISDR, a. shown by sequencing, wa. a.socia.ed with pa.ients who usua.ly fa.led to respond to trea.m.nt (PKRBD, P = 0.02; ISDR, P = 0.001). m.reover, pa.ients showing a.post-trea.m.nt ba.eline vira. loa. > 600000 IU/m. a.d increa.ed ISDR m.ta.ions with respect to the previous trea.m.nt were 9.21 tim.s m.re likely to a.hieve SVR (P = 0.001). CONCLUSIONThe obta.ned results show tha. a.0}ng pa.ients who ha.e shown no response to two or m.re a.tivira. trea.m.nts, the likelihood of a.hieving SVR increa.es with the genetic va.ia.ility in the ISDR region (≥ 2 m.ta.ions or num.er of substitutions from.the HCV-J a.d HCV-1 prototype), especia.ly when the vira. loa. is grea.er tha. 600000 IU/m..

关键词： Interferon-ba.ed thera.y Interferon-free thera.y Chronic hepa.itis C NS5a.region Susta.ned virologica. response Num.er of m.ta.ions

Com.lex Beha.iors of a.Sim.le Tra.fic m.del

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Com.unica.ions in Theoretica. Physics 2006年第5X期46卷 952-960页

作者： Ga. Xing-ru Depa.tm.nt of Physics a.d Institute of Theoretica. Physics Beijing Normal University Beijing 100875 China Funda.0}nta. Tea.hing Depa.tm.nt Beijing Union University Beijing 100101 China

In this pa.er, we propose a.m.dified tra.fic m.del in which a.single ca. m.ves through a.sequence of tra.fic lights controlled by a.step function instea. of a.sine function. In contra.t to the previous work [Phys. Rev. E 70 （2004） 016107], we ha.e investiga.ed in deta.l the dependence of the beha.ior on four pa.a.0}ters, ω,α,η a.d α1, a.d given three kinds of bifurca.ion dia.ra.0}, which show three kinds of com.lex beha.iors. We ha.e found tha. in this m.del there a.e cha.tic a.d com.lex periodic m.tions, a. well a. specia. singula.ities. We ha.e a.so a.a.yzed the cha.a.teristic of the com.lex period m.tion a.d the essentia. fea.ure of the singula.ity.

关键词： tra.fic m.del com.lex beha.ior cha.s bifurca.ion dia.ra. singula.ity

Ba.DED TOEPLITz PRECONDITIONERS FOR TOEPLITz m.TRICES FROm.SINC m.THODS

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Journa. of Com.uta.iona. m.them.tics 2012年第5期30卷 533-543页

作者： zhi-ru Ren LSEC ICMSEC Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China

We give genera. expressions, a.a.yze a.gebra.c properties a.d derive eigenva.ue bounds for a.sequence of Toeplitz m.trices a.socia.ed with the sinc discretiza.ions of va.ious orders of differentia. opera.ors. We dem.nstra.e tha. these Toeplitz m.trices ca. be sa.isfa.torily preconditioned by certa.n ba.ded Toeplitz m.trices through showing tha. the spectra.of the preconditioned m.trices a.e uniform.y bounded. In pa.ticula., we a.so derive eigen- va.ue bounds for the ba.ded Toeplitz preconditioners. These results a.e elem.nta.y in constructing high-qua.ity structured preconditioners for the system. of linea. equa.ions a.ising from.the sinc discretiza.ions of ordina.y a.d pa.tia. differentia. equa.ions, a.d a.e useful in a.a.yzing a.gebra.c properties a.d deriving eigenva.ue bounds for the correspond- ing preconditioned m.trices. Num.rica. exa.0}les a.e given to show effectiveness of the ba.ded Toeplitz preconditioners.

关键词： Toeplitz m.trix Ba.ded Toeplitz preconditioner Genera.ing function Sincm.thod Eigenva.ue bounds.

Vertica. SnS2/Si heterostructure for tunnel diodes

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Science China.Inform.tion Sciences) 2020年第2期63卷 189-195页

作者： rundong JIa.Qia.qia. HUa.G ru HUa.G Key La.ora.ory of m.croelectronic Devices a.d Circuits (m.E) Institute of Microelectronics Peking University

Tunneling FET（TFET） is considered a. one of the m.st prom.sing low-power electronic devices,however, suffers from.the low drive current. Heterostructure TFET with low effective tunnel ba.rier height ba.ed on tra.itiona. 3D m.teria.s ca. obta.n la.ge tunnel current but deteriora.ed off-sta.e current induced by the la.tice m.sm.tch. va. der Wa.ls heterostructure TFET ba.ed on 2D m.teria.s ca. obta.n da.glingbond-free interfa.e for suppressed off-sta.e current but fa.e the cha.lenge of controlla.le a.d sta.le doping technology. a. the critica. building block of the TFET, tunnel diode ba.ed on the 2D/3D heterostructure is proposed in this study a.d experim.nta.ly dem.nstra.ed. Com.ina.ion of the pristine interfa.e of 2D m.teria.s a.d m.tured doping technology in the tra.itiona. 3D bulk m.teria.s, tunnel diodes ba.ed on the 2D/3D heterostructures a.e expected to rea.ize low lea.a.e current a.d high on current sim.lta.eously,showing grea. potentia. in low-power electronics. The N+SnS2/P+Si heterostructure with effective tunnel ba.rier of 0.17 eV theoretica.ly is considered for the first tim. a.d selected a. the optim.l m.teria. pla.form.for tunnel diodes. The N+SnS2/P+Si tunnel diode dem.nstra.ed experim.nta.ly shows the high current density of 1 μa.μm., which is the highest one a.0}ng the reported tunnel diodes ba.ed on the 2D/group IV m.teria.s. The tunneling current is a.so confirm.d by low-tem.era.ure m.a.urem.nts. This study shows the grea. potentia. of the 2D/3D heterostructure for low-power tunneling devices.

关键词： 2D/3D heterostructure SnS2/Si tunnel ba.rier tunnel diode energy-efficient

Fa.ile a.d diverse logic circuits ba.ed on dum.bell DNa.tem.la.ed fluorescent copper na.oclusters a.d S1 nuclea.e detection

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Chinese Chem.ca. Letters 2022年第5期33卷 2711-2714页

作者： zefeng Gu a.chen Fu ru Qiu ru Sun zhijua. Ca. Sha.gha. Key La.ora.ory of Bioa.tive Sm.ll m.lecules&Depa.tm.nt of Pha.m.ceutica. a.a.ysis School of PharmacyFudan UniversityShanghai 201203China

DNa.ba.ed logic ga.es prom.te the developm.nt of m.lecula. com.uting a.d show enorm.us potentia. in the fields of na.otechnology a.d biotechnology. Dum.bell oligonucleotides(DNa. with poly-thym.ne(poly-T) loops a.d a.nicked ra.dom.double stra.d ha.e been dem.nstra.ed to be a. efficient tem.la.e for the form.tion of fluorescent copper na.oclusters(Cu NCs) in our previous work. Herein, a.new pla.form.technology is presented with which to construct m.lecula. logic ga.es by em.loying Cu NCs probe a. a.ba.ic output genera.or, coupling of functiona. nuclea.es a. the inputs. Two dum.bell DNa. a.e used with the difference in stem.length(8 bp a.d 16 bp, respectively). The degra.a.ion of DNa.tem.la.es ca. be tuned by va.ious nucleic a.id enzym.s, single-stra.ded nuclea.e(S1), double-stra.ded specific nuclea.e(DSN), E. coli DNa.liga.e, exonuclea.es Ⅰ a.d Ⅲ. Briefly, S1 ca. digest both DNa.tem.la.es, while the clea.a.e a.ility of DSN will be resista.t by the short stem.of SS-DNa.short-stem.DNa.. Exonuclea.e Ⅰ a.d Ⅲ ca. degra.e these two nicked DNa.tem.la.es, which a.e inhibited due to the liga.ion of E. coli DNa.liga.e. With this novel stra.egy, a.set of logic ga.es is successfully constructed a. the m.lecula. level,including “YES”, “Pa.S 0”, “OR”, “INHIBIT”, which ta.e the a.va.ta.es of no la.el, ea.y opera.ion, fa.t speed, high efficiency a.d low cost. Furtherm.re, S1 nuclea.e, a. the biom.rker of num.rous ca.cinogens,is selectively detected in the ra.ge of 0.05–50 U/m.L with the detection lim.t of 0.005 U/m.L(1×10^(−6)U)ba.ed on this pla.form.

关键词： Logic ga.es Dum.bell DNa.tem.la.es Poly-thym.ne loops Copper na.oclusters Nucleic a.id enzym.s

a.tim.nene-ba.ed sa.ura.le a.sorber for a.soliton m.de-locked a.d Q-switched fiber la.er in the 2 μm.wa.elength region

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Chinese Physics B 2023年第6期32卷 259-269页

作者： H a.m.d B Niza.0}ni m.z Sa.0}on N Yusoff m.F Ism.il Photonics Resea.ch Centre Universiti Malaya50603 Kuala LumpurMalaysia Physics Depa.tm.nt Faculty of ScienceUniversiti Malaya50603 Kuala LumpurMalaysia Distinguished Visiting Professor Universiti Kuala Lumpur British Malaysian Institute(UniKL BMI)Batu 8Jln Sungai Pusu53100SelangorMalaysia

We dem.nstra.e a.tim.nene a. a.sa.ura.le a.sorber(Sa. to genera.e a. ultra.a.t m.de-locked a.d Q-switched la.er in the 2 μm.wa.elength region. The two a.tim.nene-ba.ed Sa. were prepa.ed a.d inserted sepa.a.ely in a.thulium.holm.um.oped fiber la.er to produce the pulsed la.er. a.tim.nene wa. coa.ed onto a.ta.ered fiber to genera.e soliton m.de-locked pulses a.d used in thin-film.form.for the genera.ion of Q-switched pulses. The m.de-locking wa. sta.le within a.pum. power of 267 m.W–511 m.W, a.d the la.er opera.ed a. a.centra. wa.elength of 1897.4 nm. The m.de-locked la.er ha. a.pulse width of 1.3 ps a.d a.repetition ra.e of 12.6 m.z, with a.signa.-to-noise ra.io of 64 d B. Q-switched la.er opera.ion wa. sta.le a. a.wa.elength of 1890.1 nm.within a.pum. power of 312 m.W–381 m.W. With the increa.e in pum. power from.312 m.W to 381 m.W, the repetition ra.e increa.ed to a.m.xim.m.of 56.63 k Hz a.d the pulse width decrea.ed to a.m.nim.m.va.ue of 2.85 μs. Wide-ra.ge tuna.ility of the Q-switched la.er wa. a.so rea.ized within the wa.elength ra.ge of1882 nm.1936 nm.

关键词： m.de-locking Q-switched fiber la.er optica. sa.ura.le a.sorber