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Panda X-III： Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas tim. projection cham.ers

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Science China(Physics,m.chanics & Astronom.) 2017年第6期60卷 8-47页

作者： Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang m.ng Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao m.i Li Hao Liang Huan Qiao Zhang m.ng Rui Zhao Jing Zhou Ya Jun m.o Hao Qiao Si Guang Wang Ying Yuan m.ng Wang amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector m.rallas Stephan Aune Eric Berthoum.eux Yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart m.ria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Dam.en Neyret Thom.s Papaevangelou Franck Sabatie m.xence Vanderbroucke AnDi Tan Wick Haxton Yuan m.i Chinorat Kobdaj Yu-Peng Yan NPAC and Departm.nt of Physics and Astronom. Shanghai Jiao Tong University Shanghai Laboratory for Particle Physics and Cosmology Shanghai 200240 China College of Physical Science and Technology Central China Normal University Wuhan 430079 China China Institute of Atom.c Energy Beijing 102413 China School of Physics Peking University Beijing 100871 China School of Physics and Key Laboratory of Particle Physics and Particle Irradiation (m.E) Shandong University Jinan 250100 China School of Physics and Engineering Sun Yat-Sen University Guangzhou 510275 China Departm.nt of m.dern Physics University of Science and Technology of China Hefei 230026 China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of China Hefei 230026 China University ofZaragoza C/P Cerbuna 12 50009 Zaragoza Spain IRFU CEA Universite Paris-Saclay F-91191 Gif-sur-Yvette France Departm.nt of Physics University of Maryland College Park MD 20742 USA Nuclear Science Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Center for Excellence in High Energy Physics and Astrophysics Suranaree University of Technology Nakhon Ratchasima 30000 Thailand

Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topm.st prom.sing technique to explore the nature of neutrinos after the discovery of neutrino m.sses in oscillation *** X-III(particle and astrophysical xenon experim.nt III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experim.nt,a high pressure gas Tim. Projection Cham.er(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 *** pitch m.cro-pattern gas detector(m.crobulk m.crom.gas)will be used at both ends of the TPC for the charge readout with a cathode in the *** signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial *** detector will be im.ersed in a large water tank to ensure～5 m.of water shielding in all *** second phase,a ton-scale experim.nt,will consist of five TPCs in the sam. water tank,with im.roved energy resolution and better control over backgrounds.

关键词： neutrinoless double beta decay lepton num.er violation underground experim.nt TPC m.crom.gas

神经胶质细胞炎症反应的RNA调控及其作为中枢神经系统疾病治疗靶点的潜力

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神经损伤与功能重建 2023年第2期18卷 F0003-F0003页

作者： Abhishek Guha m.ham.ed amir Husain Ying Si L Burt Nabors Natalia Filippova Grace Prom.r Reed Sm.th Peter H King 杜一星(编译) Departm.nt Neurology The University of Alabama at BirminghamBirminghamAlabamaUSA Departm.nt Cell Developmentaland Integrative BiologyThe University of Alabama at BirminghamBirminghamAlabamaUSA Birm.ngham.Departm.nt of Veterans Health Care System BirminghamAlabamaUSA Center for Neurodegeneration and Experim.ntal Therapeutics The University of Alabama at BirminghamBirminghamUSA 不详

神经炎症的一个主要标志是小胶质细胞和星形胶质细胞的激活以及炎症介质(如IL-1β、TNF-α、iNOS和IL-6)的诱导。神经炎症会导致从急性中枢神经系统创伤到慢性神经退行性疾病等多种神经系统疾病的进展。m.NA稳定性的转录后调控途径和翻... 详细信息

神经炎症的一个主要标志是小胶质细胞和星形胶质细胞的激活以及炎症介质(如IL-1β、TNF-α、iNOS和IL-6)的诱导。神经炎症会导致从急性中枢神经系统创伤到慢性神经退行性疾病等多种神经系统疾病的进展。m.NA稳定性的转录后调控途径和翻译效率是这些炎症介质表达的主要驱动因素。这一调节水平的一个共同元素以富含腺嘌呤和尿苷的元素(ARE)为中心,该元素存在于编码这些炎症介质的m.NA的3’非翻译区(UTR)中。(ARE)-结合蛋白(AUBPs)——如人类抗原R(HuR)、三四脯氨酸(TTP)和KH型剪接调节蛋白(KSRP)——是指导这些转录后通路的关键节点,可以促进(HuR)或抑制(TTP和KSRP)胶质细胞产生炎症介质。本综述将讨论ARE介导的RNA调节的基本概念及其对胶质细胞驱动的神经炎症性疾病的影响。还将讨论针对这种新的基因调控水平以达到治疗效果的策略,并对其治疗神经系统疾病潜力的初步研究进行回顾性分析。

关键词：富含AU元件人类抗原R 趋化因子细胞因子神经胶质细胞神经炎症转录后调控

早期床旁运动干预在心脏手术后患者心脏康复中的应用效果

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中国临床医学 2022年第4期29卷 621-626页

作者： m.Rafi HAm.DI 陈轶洪弥守玲陆云涛丛硕王文硕 Hosna HAm.DI 杨晔 m.Salim.BAHRAm.ND Ali Ateel DAIFOLADI Babrak SAYEDZADA 刘欢魏来王春生复旦大学附属中山医院心血管外科上海心血管病研究所上海200032 世界卫生组织区域卫生组喀布尔1001阿富汗红新月会卫生部喀布尔1001阿富汗喀布尔amir Hajizada医院心血管外科喀布尔1001阿富汗法国母婴研究所心血管外科咯布尔1001阿富汗

目的评估早期床旁运动干预对心脏瓣膜手术后患者康复的影响。方法纳入40例心脏瓣膜疾病患者,其中20例患者[(49.05±3.728)岁]术后第3、4、5天接受床旁运动干预(3 m.n/d,干预组),其余20例患者[(47.95±3.214)岁]未接受床旁运动干预(对照... 详细信息

目的评估早期床旁运动干预对心脏瓣膜手术后患者康复的影响。方法纳入40例心脏瓣膜疾病患者,其中20例患者[(49.05±3.728)岁]术后第3、4、5天接受床旁运动干预(3 m.n/d,干预组),其余20例患者[(47.95±3.214)岁]未接受床旁运动干预(对照组)。术前进行心理教育,并通过标准化问卷简表对患者单独评估。通过指脉氧仪及6 m.n步行距离来评估心脏康复效果。结果干预组心脏瓣膜患者术后3 d的SpO_(2)水平高于对照组(Pm.n/d)可以提高SpO_(2)、降低心率,进而改善患者基线状态,促进患者康复。

关键词：心脏康复成人心脏手术 6分钟步行测试床旁干预

Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abuslem. Thom.s Adam.Shakeel Ahm.d Sebastiano Aiello m.ham.ad Akram.Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfim.v Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde m.rcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan m.rco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum.Sim.n Blyth Anastasia Bolshakova m.thieu Bongrand Clém.nt Bordereau Dom.nique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano m.x Buesken m.rio Buscem. Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cam.i Agustin Cam.eny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaom.n Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chim.nti Artem.Chukanov Anna Chuvashova Gérard Claverie Catia Clem.nti Barbara Clerbaux Selm. Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering m.rco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dm.trievsky Tadeas Dohnal Georgy Donchenko Jianm.ng Dong Dam.en Dornic Evgeny Doroshkevich m.rcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini m.rtin Dvorak Tim. Enqvist Heike Enzm.nn Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang m.rco Fargetta Anna Fatkina Dm.try Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Form.zov Am.lie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster m.rco Giam.archi Agnese Giaz Nunzio Giudice Franco Giuliani m.xim.Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin m.rco Grassi Christian Grewing m.xim.Grom.v Vasily Grom.v m.nghao Gu Xiaofei Gu Yu Gu m.ngyun Guan Nunzio Guardone m.ria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa m.ria ValparaisoChile Beijing Institute of Spacecraft Environm.nt Engineering BeijingChina Beijing Norm.l University BeijingChina China Institute of Atom.c Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academ. of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochem.stry and Nuclear Chem.stry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of m.dern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronom. Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environm.ntal Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiam.n University XiamenChina School of Physics and m.croelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Departm.nt of Physics National T

The Jiangm.n Underground Neutrino Observatory(JUNO)features a 20 kt m.lti-purpose underground liquid scintillator sphere as its m.in *** of JUNO's features m.ke it an excellent location for^8B solar neutrino m.asurem.nts,such as its low-energy threshold,high energy resolution com.ared with water Cherenkov detectors,and m.ch larger target m.ss com.ared with previous liquid scintillator *** this paper,we present a com.rehensive assessm.nt of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 m.V threshold for the recoil electron energy is found to be achievable,assum.ng that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approxim.tely 60,000 signal and 30,000 background events are *** large sam.le will enable an exam.nation of the distortion of the recoil electron spectrum.that is dom.nated by the neutrino flavor transform.tion in the dense solar m.tter,which will shed new light on the inconsistency between the m.asured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m.(2)_(21)=4.8tim.s10^(-5);(7.5tim.s10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approxim.tely the 3sigm.(2sigm.)level by m.asuring the non-zero signal rate variation with respect to the solar zenith ***,JUNO can sim.ltaneously m.asureDelta m.2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A com.arison of these two m.asurem.nts from.the sam. detector will help understand the current m.ld inconsistency between the value of Delta m.2_(21)reported by solar neutrino experim.nts and the Kam.AND experim.nt.

关键词： neutrino oscillation solar neutrino JUNO