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Role of intravenously administered hyoscine butyl bromide in retrograde terminal ileoscopy: A randomized, double-blinded, placebo-controlled trial

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World Journal of Gastroenterology 2007年第12期13卷 1820-1823页

作者： SP misra m dwivedi Department of Gastroenterology MotiLal Nehru Medical College University of Allahabad Allahabad211001 India

AIm： To evaluated the role of hyoscine butyl bromide in facilitating retrograde ileoscopy. mETHODS： Retrograde terminal ileoscopy was attempted in 200 consecutive patients undergoing colonoscopy. After intubation of the cecum and visualization of the ileocecal valve, butyl bromide injection or normal saline was given intravenously to the patients in a double blind random fashion. The pulse rate and oxygen saturation were measured continuously. After completion of the procedure, endoscopists were then asked to score the ease of intubation and the ease of visualization of the terminal ileum on a visual scale of 1 to 10. The patients were also asked to score the pain after receiving hyoscine butyl bromide injection on a score of 1 to 10. RESULTS： Terminal ileoscopy could be performed in 188 patients. The mean （SD） visual analogue score for the ease of intubation of the cecum was 7.4 （0.65） in the injection group and 5.9 （0.8） in the placebo group （P 〈 0.001）. The mean （SD） length of ileum visualized in the injection group was 14.4 （3.3） cm and 10.4 （2.7） cm in the placebo group （P 〈 0.001）. The mean （SD） visual analogue score for ease of visualization of the terminal ileum was 7.5 （0.69） in the injection group and 5.9 （0.7） in the placebo group （P 〈 0.001）. The pain score experienced by the patients was 6.5 （0.7） in the injection group and 6.7 （0.69） in the placebo group （P 〈 0.008）. Although the pulse rate increased significantly in patients receiving the drug, no statistically significant difference was noted in the oxygen saturation between the two groups either before or after administration of the drug. No complications were observed in either of the groups. CONCLUSION： Hyoscine butyl bromide injection is a useful adjunct in helping the intubation and visualization of terminal ileum during colonoscopy.

关键词： Ileoscopy Colonoscopy Colon Ileum Hyoscine Tuberculosis Inflammatory bowel disease Cancer

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Ileoscopy in 39 hematochezia patients with normal colonoscopy

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World Journal of Gastroenterology 2006年第19期12卷 3101-3104页

作者： SP misra m dwivedi V misra Department of Gastroenterology and Pathology moti Lal Nehru medical College Allahabad 211001India

AIm： To assess the role of retrograde terminal ileoscopy in hematochezia patients with normal colonoscopy. mETHODS： Between January 1997 and march 2005, 39 hematochezia patients （males 36, females 3, mean age 44.7 years） with a reported normal colonoscopy underwent a repeat colonoscopy. After reaching the cecum, attempt was made to localize the ileocecal valve and intubate the terminal ileum. Any abnormality in the mucosa of the terminal ileum was carefully recorded and biopsies were obtained from suspiciouslooking lesions. RESULTS： During the study period there were 39 patients admitted for hematochezia in whom colonoscopy till cecum did not reveal any abnormality. Fulllength colonoscopy till the cecum could be performed in all the patients. The terminal ileum could be intubated in 36 patients. No abnormality was noted in 31 patients. Ileal ulcers were noted in two patients. Noclularity along with ulceration of the ileal mucosa, a Dieulafoy＇s lesion, and an angiomatous malformation were noted in one patient each. Histological examination of the biopsies obtained from the ulcers revealed typical tuberculous lesion in the patient with nodularity and ulceration. One of the patients had typhoid ulcers and another had non-specific ulcers. CONCLUSION： Retrograde terminal ileoscopy gives limited but valuable information, in patients with hematochezia and should be attempted in all such patients.

关键词： Endoscopy Ileum Colon Diagnosis Tuberculosis Ulcer GI bleeding

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Assessing temporal variation of coloured dissolved organic matter in the coastal waters of South Eastern Arabian Sea

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Acta Oceanologica Sinica 2020年第1期39卷 102-109页

作者： P minu V P Souda S K Baliarsingh R m dwivedi Y Ali P m Ashraf ICAR-Central Institute of Fisheries Technology Matsyapuri P.O.Cochin 682029India Indian National Centre for Ocean Information Services(INCOIS) Hyderabad 500090India Department of Geology Aligarh Muslim UniversityAligarh 202001India

Coloured dissolved organic matter(CDOm) plays a major role in marine photochemical and biological processes and its optical properties are known to affect the underwater light penetration. This paper highlights in situ optical estimation and satellite retrieval of CDOm in deciphering its temporal variations in coastal waters of the South Eastern Arabian Sea. The study accentuated the source of CDOm as terrigenous origin during monsoon, of in situ productions during pre-monsoon and during post-monsoon of autochthonous-allocthonous origin. The matchup analysis for in situ and mODIS Aqua retrieved Adg443 exhibited bias which decreased by incorporating the seasonal component. The study also identified degrading bloom of Noctiluca scintillans as the source for exceptionally high CDOm in the area during January and February. The study demands to incorporate seasonal components and phytoplankton abundance while assessing the performance of CDOm algorithms in optically complex coastal waters.

关键词： CDOm absorption chlorophyll mODIS Arabian Sea

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Study of Intermolecular Interactions in Liquid Crystals: Para-butyl-p’-cyano-biphenyl

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Journal of Crystallization Process and Technology 2014年第1期4卷 31-38页

作者： K. K. dwivedi m. K. dwivedi S. N. Tiwari Department of Physics D.D.U. Gorakhpur University Gorakhpur India.

Various characteristics of mesomorphism can be explained using intermolecular interactions between a pair of liquid crystalline molecules. The intermolecular interactions have been calculated considering multipole-multicentere expansion method and modified by second order perturbation treatments. For calculation of multipole i.e. charge, dipole, etc. at each atomic center of molecules, para-butyl-p’-cyano-biphenyl, GAmESS, an ab initio program, with 6-31G* basis set has been used. The stacking, in-plane and terminal interaction energies explain the liquid crystalline behaviour of the system.

关键词： Liquid Crystals Phase Transition Intermolecular Interactions GAmESS multicentred-multipole Expansion

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Frequency of Cyclonic Disturbances and Changing Productivity Patterns in the North Indian Ocean Region: A Study Using Sea Surface Temperature and Ocean Colour Data

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International Journal of Geosciences 2012年第3期3卷 490-506页

作者： madhumita Tripathy mini Raman R. m. dwivedi Ajai Ajai marine Planetary Earth Science Group Space Applications Centre (ISRO) Ahmedabad-15 India

In recent years we are observing devastating cyclones like Nargis, Gonu, Sidr, Liala, Phet etc in the North Indian Ocean associated with heavy rains, thunderstorm, high tide and intense winds that caused shocking destructions in the coastal areas. As these are originating over the Ocean and propagating towards land, they also change physical property as well as biological structure of the Ocean. In recent years, several attempts were made to associate tropical cyclone trends with climate change resulting from green house warming. The studies have indicated an increase in intense cyclones in the Arabian Sea. Time series analysis of ocean colour data have revealed rapid and profound change in the productivity pattern over the last few years in the Arabian Sea that appears to be related to the warming trends being experienced over the Asian subcontinent. In view of the above, a study was carried out to examine the frequency of cyclonic disturbances in the Arabian Sea and the Bay of Bengal and its effect in modulating the productivity patterns. Data on the monthly and annual occurrences of tropical cyclones in the Bay of Bengal and the Arabian Sea were collected from 1908 to 2007 from SAARC meteorological Research Centre and Indian meteorological Department. Sea surface temperature (SST) from NOAA-AVHRR and phytoplankton biomass indexed as chlorophyll-a concentration from Sea WiFs for ten years (1998-2007) were used to study the physical and biological effects of cyclonic events in the Arabian Sea (AS) and the Bay of Bengal (BOB). Analysis of the monthly and annual occurrences of tropical cyclone reveals an increasing trend of cyclonic disturbances in the AS whereas there is a decreasing trend in the BOB in the last decade (1998-2007). SST analysis indicates decrease in monthly average SST by 1.5℃ to 1.75℃ in the AS and 1.5℃ to 1.25℃ in the BOB in the pre-monsoon season. Phytoplankton biomass was observed to increase by a factor of two after the passage of cyclone. Resu

关键词： Cyclonic Events Arabian Sea Bay of Bengal SST Chlorophyll-a Ecological Structure

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Synthesis and enhanced photoluminescence properties of red emitting divalent ion(Ca^(2+))doped Eu:Y_(2)O_(3)nanophosphors for optoelectronic applications

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Journal of Rare Earths 2022年第8期40卷 1187-1198页

作者： Arpita dwivedi monika Srivastava Ankur dwivedi Amit Srivastava Anurag mishra S.K.Srivastava Department of Physics Institute of ScienceBanaras Hindu University(BHU)Varanasi221005India School of materials Science and Technology Indian Institute of Technology(BHU)Varanasi221005India Department of mining Engineering Indian Institute of Technology(BHU)Varanasi221005India Department of Physics TDPG College VBS Purvanchal UniversityJaunpur222001India

This work presents the synthesis of Y_(2)O_(3):Eu^(3+),χCa^(2+)(χ=0 mol%,1 mol%,3 mol%,5 mol%,7 mol%,9 mol%,11 mol%)nanophosphors with enhanced photoluminescence properties through a facile solution combustion method for optoelectronic,display,and lighting *** X-ray diffraction(XRD)patterns of the proposed nanophosphor reveal its structural properties and crystalline *** transmission electron microscope(TEm)results confirm the change in the shape of the particle and aggregation of particles after co-doping with Ca^(2+).Fourier transform infrared spectroscopy(FTIR)and Raman vibrations also confirm the presence of Y-O vibration and subsequently explain the crystalline nature,structural properties,and purity of the *** the synthesized nanophosphors samples emit intense red emission at 613 nm(~5D_(0)→~7 F_(2))under excitation with 235,394 and 466 nm wavelengths of Eu^(3+)*** photoluminescence(PL)emission spectra excited with 235 nm illustrate the highest emission peak with two other emission peaks excited with 466 and 394 nm that is 1.4 times higher than 466 nm and 1.9 times enhanced by 394 nm wavelength,*** emission intensity of Y_(2)O_(3):Eu^(3+),χCa^(2+)(5 mol%)is increased 8-fold as compared to Eu:Y_(2)O_(3).Doping with Ca^(2+)ions enhances the emission intensity of Eu:Y_(2)O_(3)nanopho sphors due to an increase in energy transfer in Ca^(2+)→Eu^(3+)through asymmetry in the crystal field and by introduction of radiative defect centers through oxygen vacancies in the yttria *** is also observed that the optical band gap and the lifetime of the~5D_(0)level of Eu^(3+)ions in Y_(2)O_(3):Eu^(3+),xCa^(2+)nanophosphor sample gets changed with a doping conce ntration of Ca^(2+)*** also reveals high thermal stability and quantum yield as estimating activation energy of 0.25 eV and 81%,***,CCT,and color purity values(>98%)show an improved red-emitting nanophosphor in the warm region of light,which m

关键词： Red emission Photoluminescence(PL) Y_(2)O_(3):Eu^(3+),xCa^(2+) Rare earths Nanophosphors LEDs

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Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

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Upper ocean high resolution regional modeling of the Arabian Sea and Bay of Bengal

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Acta Oceanologica Sinica 2019年第5期38卷 32-50页

作者： dwivedi Suneet mishra Alok Kumar Srivastava Atul K Banerjee Centre of Atmospheric and Ocean Studies and m N Saha Centre of Space Studies University of Allahabad

In this paper, effort is made to demonstrate the quality of high-resolution regional ocean circulation model in realistically simulating the circulation and variability properties of the northern Indian Ocean(10°S–25°N,45°–100°E) covering the Arabian Sea(AS) and Bay of Bengal(BoB). The model run using the open boundary conditions is carried out at 10 km horizontal resolution and highest vertical resolution of 2 m in the upper *** surface and sub-surface structure of hydrographic variables(temperature and salinity) and currents is compared against the observations during 1998–2014(17 years). In particular, the seasonal variability of the sea surface temperature, sea surface salinity, and surface currents over the model domain is studied. The highresolution model's ability in correct estimation of the spatio-temporal mixed layer depth(mLD) variability of the AS and BoB is also shown. The lowest mLD values are observed during spring(march-April-may) and highest during winter(December-January-February) seasons. The maximum mLD in the AS(BoB) during December to February reaches 150 m (67 m). On the other hand, the minimum mLD in these regions during march-April-may becomes as low as 11–12 m. The influence of wind stress, net heat flux and freshwater flux on the seasonal variability of the mLD is discussed. The physical processes controlling the seasonal cycle of sea surface temperature are investigated by carrying out mixed layer heat budget analysis. It is found that air-sea fluxes play a dominant role in the seasonal evolution of sea surface temperature of the northern Indian Ocean and the contribution of horizontal advection, vertical entrainment and diffusion processes is small. The upper ocean zonal and meridional volume transport across different sections in the AS and BoB is also computed. The seasonal variability of the transports is studied in the context of monsoonal currents.

关键词： Indian Ocean modeling Arabian Sea and Bay of Bengal mixed layer depth transport

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Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

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mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

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