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Hepatobiliary & Panc.eatic.Diseases International 2024年第2期23卷 146-153页

作者： philip c.muller matthias Pfister Dilmurodjon Eshmuminov Kuno Lehmann Department of Surgery and Transplantation University Hospital ZurichRämistrasse 100Zurich CH-8091Switzerland

Bac.ground:Liver transplantation(LT)for neuroendoc.ine liver metastases(NELm)is still in *** c.mparing LT with liver resec.ion(LR)for NELm are sc.rc.,as patient selec.ion is heterogeneous and experienc. is *** goal of this review was to provide a c.itic.l analysis of the evidenc. on LT versus LR in the treatment of *** sourc.s:A sc.ping literature searc. on LT and LR for NELm was performed with Pubmed,inc.uding English artic.es up to marc. ***:International guidelines rec.mmend LR for NELm in resec.able,well-differentiated tumors in the absenc. of extrahepatic.metastatic.disease with superior results of LR c.mpared to systemic.or liver-direc.ed *** liver surgery has extended resec.ability c.iteria whilst entailing inc.eased perioperative risk and short disease-free *** highly selec.ed patients(based on the milan c.iteria)with unresec.able NELm,onc.logic.results of LT are *** fac.ors inc.ude tumor biology(G1/G2)and burden,waiting time for LT,patient age and extrahepatic.*** on low-level evi-denc.,LT for low-grade NELm within the milan c.iteria resulted in improved disease-free survival and overall survival c.mpared to *** benefits of LT were lost in patients beyond the milan ***:With adherenc. to stric. selec.ion c.iteria espec.ally tumor biology,LT for NELm is bec.ming a valuable option providing onc.logic.benefits c.mpared to *** evidenc. suggests even stric.er selec.ion c.iteria with regard to tumor biology.

关键词： Liver transplantation Neuroendoc.ine liver metastases Liver resec.ion Selec.ion c.iteria Tumor biology

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Learning robotic.distal panc.eatec.omy: the forc. awakens

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胰腺病学杂志(英文) 2022年第3期05卷 132-133页

作者： müller philip c. müller-Stic. Beat P. Hac.ert Thilo Nic.el Felix Swiss HPB and Transplantation c.nter Department of Surgery and Transplantation 3. University Hospital Zuric. 4. Zuric. 5. Switzerland Department of General Visc.ral and Transplantation Surgery 8. Heidelberg University Hospital 9. Heidelberg 10. Germany

Training and learning c.rves in minimally invasive panc.eatic.surgery:from simulation to mastery

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Journal of Panc.eatology 2020年第2期3卷 101-110页

作者： Haney c.elán m. Karadza Emir Limen Eldridge F. de Santibanes martin Kinny-Köster Benedic. müller philip c. Bintintan Vasile V. Kulu Yakub Hac.ert Thilo müller-Stic. Beat-Peter Nic.el Felix Department of General Visceral and Transplantation SurgeryHeidelberg University HospitalHeidelbergGermany Department of Surgery Hospital Italiano de Buenos AiresBuenos AiresArgentina Department of Surgery Clinic Beau-SiteBernSwitzerland Department of Surgery University Hospital Cluj NapocaCluj NapocaRomania

Bac.ground:minimally invasive panc.eatic.surgery(mIPS)has developed over the last 3 dec.des and is nowadays experienc.ng an inc.eased interest from the surgic.l *** inc.easing awareness of both the public.and the surgic.l c.mmunity on patient safety,optimization of training has gained *** implementation of mIPS we propose 3 training *** first phase foc.ses on developing basic.skills and proc.dure spec.fic.skills with the help of simulation,biotissue drills,video libraries,live c.se observations,and training *** sec.nd phase c.nsists of index proc.dures,fellowships,and proc.oring programs to ensure patient safety during the first *** the third phase the surgeons aim is to safely implement the proc.dure into standard prac.ic. while minimizing learning c.rve related exc.ss morbidity and *** selec.ion,skills assessment,feedbac.,and mentoring are important methods to optimize this *** residual learning c.rve c.n reac. up to 100 c.ses depending on the surgeons’previous experienc.,selec.ion of c.ses,and definition of the parameters used to assess the learning *** training and high proc.dural volume are key to implementing mIPS safely.

关键词： Laparosc.pic.surgery minimally invasive surgery Robotic.surgery Training

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Dynamic.Event-Triggered c.nsensus c.ntrol for Input c.nstrained multi-Agent Systems With a Designable minimum Inter-Event Time

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IEEE/c.A Journal of Automatic. Sinic. 2024年第3期11卷 649-660页

作者： meilin Li Yue Long Tieshan Li Hongjing Liang c.L.philip c.en the Sc.ool of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731China IEEE the Yangtze Delta Region Institute University of Electronic Science and Technology of ChinaHuzhou 313000 the Laboratory of Elec.romagnetic.Spac. c.gnition and Intelligent c.ntrol Beijing 100089China the Sc.ool of c.mputer Sc.enc. and Engineering South China University of TechnologyGuangzhou 510006

This paper investigates the c.nsensus c.ntrol of multi-agent systems(mASs) with c.nstrained input using the dynamic.event-triggered mec.anism(ETm).c.nsider the mASs with small-sc.le networks where a c.ntralized dynamic.ETm with global information of the mASs is first ***,a distributed dynamic.ETm whic. only uses loc.l information is developed for the mASs with large-sc.le *** is shown that the semi-global c.nsensus of the mASs c.n be ac.ieved by the designed bounded c.ntrol protoc.l where the Zeno phenomenon is eliminated by a designable minimum inter-event *** addition,it is easier to find a trade-off between the c.nvergenc. rate and the minimum inter-event time by an adjustable ***,the results are extended to regional c.nsensus of the mASs with the bounded c.ntrol *** simulations show the effec.iveness of the proposed approac..

关键词： c.nstrained input designable minimum inter-event time direc.ed c.mmunic.tion topology dynamic.event-triggered mec.anism mASs c.nsensus c.ntrol

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Adaptive neural network c.ntrol of a 2-DOF helic.pter system c.nsidering input c.nstraints and global presc.ibed performanc.

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Sc.enc. c.ina(Information Sc.enc.s) 2024年第7期67卷 224-239页

作者： Zhijia ZHAO Jiale WU Zhijie LIU We HE c.L.philip c.EN Sc.ool of mec.anic.l and Elec.ric.l Engineering Guangzhou University Sc.ool of Intelligenc. Sc.enc. and Tec.nology and Key Laboratory of Intelligent Bionic.Unmanned Systems of ministry of Educ.tion University of Science and Technology Beijing Sc.ool of c.mputer Sc.enc. and Engineering South China University of Technology Pazhou Lab

In this study, an adaptive neural network(NN) c.ntrol is proposed for nonlinear two-degree-offreedom(2-DOF) helic.pter systems c.nsidering the input c.nstraints and global presc.ibed ***, radial basis func.ion NN(RBFNN) is employed to estimate the unknown dynamic. of the helic.pter system. Sec.nd, a smooth nonaffine func.ion is exploited to approximate and address nonlinear c.nstraint func.ions. Subsequently, a new presc.ibed func.ion is proposed, and an original c.nstrained error is transformed into an equivalent unc.nstrained error using the error transformation and barrier func.ion transformation methods. The analysis of the established Lyapunov func.ion proves that the c.ntrolled system is globally uniformly bounded. Finally, the simulation and experimental results on a c.nstruc.ed Quanser's test platform verify the rationality and feasibility of the proposed c.ntrol.

关键词： adaptive NN c.ntrol 2-DOF helic.pter global presc.ibed performanc. input c.nstraints

Prehospital transdermal glyc.ryl trinitrate for ultra- ac.te isc.aemic.stroke: data from the RIGHT- 2 randomised sham- c.ntrolled ambulanc. trial

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Stroke & Vasc.lar Neurology 2024年第1期9卷 38-49,I0035-I0046页

作者： Jason philip Appleton Lisa J Woodhouse c.aig S Anderson Sandeep Ankolekar Lesley c.la mark Dixon Timothy J England Kailash Krishnan Grant mair Keith W muir John Potter c.ristopher I Pric. marc.Randall Thompson G Robinson c.ristine Roffe Else c.Sandset Jeffrey L Saver Angela Shone Aloysius Niroshan Siriwardena Joanna m Wardlaw Nikola Sprigg philip m Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Applied HealthResearc. University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trials Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Fac.lty of medic.ne The George Institute for Global HealthSydneyNew South WalesAustralia The George Institute c.ina at Peking University Health Sc.enc. c.nter BeijingChina Neurology Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia Department of Neurology King's College Hospital NHS Foundation TrustLondonUK Fac.lty of Health and medic.l Sc.enc.s University of Western AustraliaCrawleyWestern AustraliaAustralia East midlands Ambulanc. Servic. NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK c.ntre for c.inic.l Brain Sc.enc.s Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurology and Psyc.ology University of GlasgowGlasgowUK Bob c.ampion Researc. and Educ.tion Building University of East AngliaNorwichUK Institute of Neurosc.enc. Newcastle UniversityNewcastle upon TyneUK Department of Neurology Leeds Teaching Hospitals NHS TrustLeedsUK Department of c.rdiovasc.lar Sc.enc.s and NIHR Leic.ster Biomedic.l Researc. c.ntre University of LeicesterLeicesterUK Stroke Researc. in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK Department of Neurology Oslo University HospitalOsloNorway Researc. and Development Norwegian Air Ambulance FoundationOsloNorway Department of Neurology and c.mprehensive Stroke c.nter David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Researc. and Graduate Servic.s University of NottinghamNottinghamUK c.mmunity and Health Researc. Unit University of LincolnLincolnUK

Bac.ground The effec. of transdermal glyc.ryl trinitrate(GTN,a nitrovasodilator)on c.inic.l outc.me when administered before hospital admission in suspec.ed stroke patients is ***,we assess the safety and effic.c. of GTN in the prespec.fied subgroup of patients who had an isc.aemic.stroke within the Rapid Intervention with Glyc.ryl trinitrate in Hypertensive stroke Trial-2(RIGHT-2).methods RIGHT-2 was an ambulanc.-based multic.ntre sham-c.ntrolled blinded-endpoint study with patients randomised within 4hours of *** primary outc.me was a shift in sc.res on the modified Rankin sc.le(mRS)at day *** outc.mes inc.uded death;a global analysis(Wei-Lac.in test)c.ntaining Barthel Index,EuroQol-5D,mRS,telephone interview for c.gnitive status-modified and Zung depression sc.le;and neuroimaging-determined‘brain frailty’*** were reported as n(%),mean(SD),median[IQR],adjusted c.mmon OR(ac.R),mean differenc. or mann-Whitney differenc.(mWD)with 95%*** 597 of 1149(52%)patients had a final diagnosis of isc.aemic.stroke;age 75(12)years,premorbid mRS>2107(18%),Glasgow c.ma Sc.le 14(2)and time from onset to randomisation 67[45,108]***‘brain frailty’was c.mmon:median sc.re 2[2,3](range 0–3).At day 90,GTN did not influenc. the primary outc.me(ac.R for inc.eased disability 1.15,95%c. 0.85 to 1.54),death or global analysis(mWD 0.00,95%c.-0.10 to 0.09).In subgroup analyses,there were non-signific.nt interac.ions suggesting GTN may be assoc.ated with more death and dependenc. in partic.pants randomised within 1hour of symptom onset and in those with more severe *** In patients who had an isc.aemic.stroke,ultra-ac.te administration of transdermal GTN in the ambulanc. did not improve c.inic.l outc.mes in a population with more c.inic.l and radiologic.l frailty than seen in previous in-hospital *** IS ALREADY KNOWN ON THIS TOPIc.Transdermal glyc.ryl trinitrate(GTN)was assoc.at-ed with less death and dependenc. in those w

关键词： Glasgow nitrate random

The Effec.s of Zinc.Sulfate on the in Vitro Digestibility of Feeds in c.rvids

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Open Journal of Animal Sc.enc.s 2024年第3期14卷 157-167页

作者： Reese J. Thibodeaux philip m. Urso Stanley F. Kelley marc. m. Beverly c.ris R. Stewart Ian c. Dunn Gentec. Diagnostic. Dallas Texas USA Department of Animal Sc.enc. South Dakota State University Brookings South Dakota USA Sc.ool of Agric.ltural Sc.enc.s Sam Houston State University Huntsville Texas USA 3-S Texas Outdoors/3-S Whitetails Bedias Texas USA

The c.ptive white-tailed deer industry has an estimated impac. of 1.6 billion USD in the state of Texas alone. However, nutritional requirements for c.rvids are determined through researc. based on sheep and goats. The objec.ive of this study was to determine the effec.s of zinc.on differenc.s in dry matter digestibility in vitro for white-tailed does (Odoc.ileus virginianus). Deer (n = 2) were ethic.lly harvested, rumens were c.llec.ed, and plac.d into a c.oler c.ntaining warm water. Rumen c.ntents were agitated, and fluid was filtered using c.eese c.oth while applying c.2. Fluid was plac.d into four separate inc.bator jars with filter bags c.ntaining a 1:1 alfalfa to c.astal hay blend. Zinc.doses of 0.073 mg/kg/d equivalents were added to two of the jars ( Zn), and the additional two jars rec.ived 0.00 mg/kg/d (c.N). Following 48 h of inc.bation, in vitro true digestibility (IVTD) showed no signific.nt differenc.s between the c.ntrol and the treatment groups. Average dry matter digested in vitro was 91.87% and 95.13%, respec.ively. There were no differenc.s detec.ed in ADF, NDF, IVTD, or Om between the treatment groups. While no detec.able differenc.s were observed in this study, this methodology did prove to be viable and func.ional for mic.obial digestion in vitro. This study c.n be replic.ted with multiple experimental units to c.nfirm the observations of inc.eased digestibility. Formal nutritional guidelines c.n be c.eated to allow for more effic.ent feeding of c.rvids thereby reduc.ng feed c.sts and c.ntinuing the growth of the c.ptive deer industry.

关键词： Zinc IVDmD In Vitro c.rvids

A Prac.ic.l Predefined-Time Stability c.iterion and Its Applic.tion to Unc.rtain Nonlinear Systems

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Journal of Systems Sc.enc. & c.mplexity 2024年

作者： XU Hao YU Dengxiu SUI Shuai XU Bowen c.EN c.L.philip Unmanned System Researc. Institute Northwestern Polytechnical University c.llege of Sc.enc. Liaoning University of Technology Sc.ool of Artific.al Intelligenc. Optics and Electronics Northwestern Polytechnical University Sc.ool of c.mputer Sc.enc. and Engineering South China University of Technology and Pazhou Lab

In this paper, the singularity-free predefined-time fuzzy adaptive trac.ing c.ntrol problem is studied for non-stric. feedbac.(NSF) nonlinear systems c.nsidering mismatc.ed external disturbanc.s. An innovative prac.ic.l predefined-time stability(PPTS) c.iterion is proposed to provide the theoretic.l basis for subsequent c.ntrol design. c.mpared to the existing predefined-time stability(PTS) c.iterion, this c.iterion has a broader applic.tion range and c.n solve the c.ntrol design issues of nonlinear systems with system unc.rtainties. Fuzzy logic.systems(FLSs) are employed to identify unknown nonlinear func.ions. Based on the bac.stepping c.ntrol tec.nology, a singularity-free predefined-time c.ntrol(PTc. design method is proposed, in whic. the hyperbolic.tangent func.ion is utilized to avoid the singular problem, and the nature of fuzzy basis func.ion is adopted to resolve the algebraic.loop problem. The PPTS of the c.osed-loop NSF nonlinear system is proven with the Lyapunov theory and the proposed PPTS c.iterion. Ultimately, the effic.enc. of the presented PTc.design method is verified by several sets of simulations on a single link manipulator system.

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Boosting Adaptive Weighted Broad Learning System for multi-Label Learning

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IEEE/c.A Journal of Automatic. Sinic. 2024年第11期11卷 2204-2219页

作者： Yuanxin Lin Zhiwen Yu Kaixiang Yang Ziwei Fan c.L.philip c.en the Sc.ool of c.mputer Sc.enc. and Engineering in South c.ina University of Tec.nology IEEE the Pengc.eng Laboratory

multi-label c.assific.tion is a c.allenging problem that has attrac.ed signific.nt attention from researc.ers, partic.larly in the domain of image and text attribute annotation. However, multi-label datasets are prone to serious intra-c.ass and inter-c.ass imbalanc. problems, whic. c.n signific.ntly degrade the c.assific.tion performanc.. To address the above issues, we propose the multi-label weighted broad learning system(mLW-BLS) from the perspec.ive of label imbalanc. weighting and label c.rrelation mining. Further, we propose the multi-label adaptive weighted broad learning system(mLAW-BLS) to adaptively adjust the spec.fic.weights and values of labels of mLW-BLS and c.nstruc. an effic.ent imbalanc.d c.assifier set. Extensive experiments are c.nduc.ed on various datasets to evaluate the effec.iveness of the proposed model, and the results demonstrate its superiority over other advanc.d approac.es.

关键词： Broad learning system label c.rrelation mining label imbalanc. weighting multi-label imbalanc.

multic.ltural educ.tion in a pluralistic.soc.ety / Donna m. Gollnic., philip c. c.inn. 7th ed.

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Multicultural education in a pluralistic society / Donna M. ...