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Assessment of cO_(2)storage prospect based on physical properties of Rio Bonito Formation rock units

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Energy Geoscience 2024年第1期5卷 321-330页

作者： Richardson m.Abraham-A Stephanie San martín cañas Isabella F.S.miranda colombo c.G.Tassinari Institute of Energy and Environment(IEE) University of São Paulo(USP)Brazil Research centre for Greenhouse Gas Innovation(RcGI) University of Sãao Paulo(USP)Brazil

The physical properties of the rock units associated with the Rio Bonito Formation are presented in this study with the focus on modelling reservoir quality based on petrophysics-derived parameters to evaluate cO_(2)storage *** involves the modelling of the reservoir depths,thicknesses,flow zone indicators(FZI),and effective permeability(Keff)and presenting the cO_(2)storage efficiency factors peculiar to the rock units of the study *** results presented by this study for the stated objectives are not quite common in the *** values range from 200 mD to higher than 2000 mD,and FZI values are generally above 1.0 mm and up to 13.0 mm within the portions covered by the drilled *** sandstone units recorded are up to 20 m thick in some *** Keff and FZI models indicate the sandstone reservoirs as permeable units to support the injection and circulation of cO_(2)within the potential reservoir units of the Rio Bonio Formation across São Paulo *** from some points in the southeastern part of the study location,where the Rio Bonito are delineated at depths less than 800 m(minimum cO_(2)storage depth based on best practices),other portions are deeper,ranging from 950 m to 3500 ***-bedded layers will affect the integrity of the rocks as cO_(2)storage tanks or reservoir seals/traps/overburden within the *** bed thicknesses are up to 20 m in some ***,hybrid cO_(2)reservoir units are feasible,especially in portions where thin siltstone layers are sandwiched between sandstone units to provide considerable thicknesses based on cO_(2)storage *** current study shows that useable areas considering reservoir thickness,depth,and other physical qualities will significantly control the cO_(2)storage efficiency of the study *** studies featuring a detailed geophysical exploration of the site to confirm the availability and saturations of preexisting fluid(hydrocarbon and water)are encouraged

关键词： Rio Bonito Effective permeability Fluid transmissibility cO_(2)storage prospect Reservoir quality Overburden integrity Flow zones

Biofabrication of nanocomposite-based scaffolds containing human bone extracellularmatrix for the differentiation of skeletal stem and progenitor cells

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Bio-Design and manufacturing 2024年第2期7卷 121-136页

作者： Yang-Hee Kim Janos m.Kanczler Stuart Lanham Andrew Rawlings marta Roldo Gianluca Tozzi Jonathan I.Dawson Gianluca cidonio Richard O.c.Oreffo Faculty of medicine Bone and Joint Research GroupCentre for Human DevelopmentStem Cells and RegenerationInstitute of Developmental SciencesUniversity of SouthamptonSouthampton SO166YDUK School of Pharmacy and Biomedical Science University of PortsmouthPortsmouth PO12DTUK School of Engineering Faculty of Engineering and ScienceUniversity of GreenwichGreenwich ME44TBUK center for Life Nano-and Neuro-Science(cLN2S) Italian Institute of Technology00161 RomeItaly

Autograft or metal implants are routinely used in skeletal ***,they fail to provide long-term clinic.l resolution,necessitating a functional biomimetic tissue engineering *** use of native human bone tissue for synthesizing a biomimeticmaterial inkfor three-dimensional(3D)bioprintingof skeletal tissueis anattractivestrategyfor ***,human bone extracellular matrix(bone-Ecm)offers an exciting potential for the development of an appropriate microenvironment for human bone marrow stromal cells(HBmScs)to proliferate and differentiate along the osteogenic.*** this study,we engineered a novel material ink(LAB)by blending human bone-Ecm(B)with nanoclay(L,Laponite®)and alginate(A)polymers using extrusion-based *** inclusion of the nanoﬁller and polymeric material increased the rheology,printability,and drug retention properties and,critically,the preservation of HBmScs viability upon *** composite of human bone-Ecm-based 3D constructs containing vascular endothelial growth factor(VEGF)enhanced vascularization after implantation in an ex vivo chick chorioallantoic membrane(cAm)*** inclusion of bone morphogenetic protein-2(BmP-2)with the HBmScs further enhanced vascularization and mineralization after only seven *** study demonstrates the synergistic combination of nanoclay with biomimetic materials(alginate and bone-Ecm)to support the formation of osteogenic.tissue both in vitro and ex vivo and offers a promising novel 3D bioprinting approach to personalized skeletal tissue repair.

关键词： Extracellular matrix Nanoclay Bone 3D bioprinting

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A toast to a zebrafish germ cell induction cocktail

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Science china(Life Sciences) 2024年第6期67卷 1314-1315页

作者： mary c.mullins Department of cell and Developmental Biology University of Pennsylvania Perelman School of MedicinePhiladelphia 19104USA

The zebrafish field is ringing in the new year with a publication from Yonghua Sun's laboratory(Wang et al.,2023)of a cocktail of germline factors that can induce all cells of the zebrafish embryo into primordial germ cells(PGcs)at phenomenal *** major advance is not only of great interest to germ cell biologists,but it has important applications to the entire zebrafish field,as shown in Wang et al.(2023).

关键词： fish zebra field

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Treatment of Vulvovaginal candidiasis with A Strategy Based on Phototherapy (m.A.c.^® Scar Acceleration method)

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modern Research in Inflammation 2024年第1期13卷 1-7页

作者： marcus Vinic.us de mello Pinto Karin Yuri Fernández Iturra Aline Ronis Sampaio maría Elena Silva Álvarez Esteban Fortuny celulare Institute Petrópolis Brazil Bienus clinic Santiago Chile Fisiocare Curicó Chile Universidad Finis Terrae Santiago Chile

candidiasis, also known as candidiasis vulvovaginitis, is an infection caused by different types of candida fungi, the most frequent being candida albicans. The present study reports an effective strategy, which opens new avenues for the treatment of this public health problem. The mAc® methodology, conventional laser light-emitting (LLLT)/LED) methods are based on the biphasic response demonstrated many times in LLLT research and as with other forms of drugs, a “drug” (irradiation parameters) and a “dose” (irradiation times) and the “Arndt-Schulz Law” is often cited as a suitable model to describe the dose-dependent effects of LLLT. This method uses photopharmaceuticals, cell markers and the use of correct parameters for each case to induce the acceleration of tissue repair. The present study shows a case of a 32-year-old patient diagnosed with recurrent candidiasis 4 years ago. Eighteen sessions were performed (every other day) using a photoactivated component (methylene blue 1% + clotrimazole 1%) and LED phototherapy (red, blue and violet) with emission times of 60 - 260 seconds for each applicator, according to the dose recommendations of the scar acceleration method (mAc®). At the sixth treatment session there was a noticeable decrease in the itching sensation reported by the patient. In session 11 she reported feeling a great improvement, indicating that she no longer felt itching in any area after 18 sessions. The present case demonstrates new methodologies to treat common problems in the population that have a positive impact on the quality of life. This methodology has a promising future because it is non-invasive and requires a great biological transformation for inflammatory, fungal and viral control.

关键词： Treatment of vulvovaginal candidiasis candidiasis candida m.A.c. mAc®

Frequency-dependent viscoelasticity effects on the wave attenuation performance of multi-layered periodic foundations

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Applied mathematics and mechanic.(English Edition) 2024年第3期45卷 407-424页

作者： m.SAFI m.VAKILIFARD m.J.mAHmOODI Faculty of civil Water&Environmental EngineeringShahid Beheshti UniversityTehran ***Iran Faculty of mechanic.l and Energy Engineering Shahid Beheshti UniversityTehran ***Iran

In this paper,layered periodic foundations(LPFs)are numerically examined for their responses to longitudinal and transverse modes in the time and frequency *** different unit-cells,i.e.,2-layer,4-layer,and 6-layer unit-cells,comprising concrete/rubber,concrete/rubber/steel/rubber,and concrete/rubber/steel/rubber/lead/rubber materials,respectively,are taken into ***,the viscoelasticity behavior of the rubber is modeled with two factors,i.e.,a frequency-independent(FI)loss factor and a linear frequency-dependent(FD)loss *** the extraction of the complex dispersion curves and the identification of the band gaps(BGs),the simulations of wave transmission in the time and frequency domains are performed using the cOmSOL *** parametric studies evaluate the effects of the rubber viscoelasticity models on the dispersion curves and the wave transmission for the longitudinal and transverse *** results show that considering the rubber viscoelasticity enhances the wave attenuation ***,the transverse-mode damping is more sensitive to the viscoelasticity model than its longitudinal *** 6-layer unit-cell LPF exhibits the lowest BG,ranging from 4.8 Hz to 6.5 Hz.

关键词： layered metamaterial periodic foundation complex dispersion curve wave transmission diagram

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The Iberian Roma Population Variant Server(IRPVS)

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Journal of Genetics and Genomics 2024年第7期51卷 769-773页

作者： Fabiola mavillard Javier Perez-Florido Francisco m.Ortuño Amador Valladares miren L.Álvarez-Villegas Gema Roldán Rosario carmona manuel Soriano Santiago Susarte Pilar Fuentes Daniel López-López Ana maría Nuñez-Negrillo Alejandra carvajal Yolanda morgado Daniel Arteaga Rosa Ufano Pablo mir Juan F.Gamella Joaquín Dopazo carmen Paradas macarena cabrera-Serrano Instituto de Biomedicina de Sevilla(IBiS) Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain centro Investigación Biomédica en Red Enfermedades Neurodegenerativas(cIBERNED) Instituto de Salud CarlosⅢSevillaSpain Plataforma Andaluza de medicina computacional Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevillaSpain Grupo de medicina computacional de sistemas Instituto de Biomedicina de Sevilla(IBiS)Hospital Virgen del RocíoSevillaSpain Nodo de Genómica Funcional (INB-ELIXIR-es)Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevilla 41013Spain Bioinformática en Enfermedades raras(BiER) Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)Instituto de salud CarlosⅢSevillaSpain Departamento de Ingeniería de computadores Automática y RobóticaUniversidad de GranadaGranadaSpain Servicio de Urgencias de Atención Primaria Distrito SevillaSevillaSpain centro de Servicios Sociales Negociado de Servicios EspecializadosAyuntamiento de SevillaSevillaSpain Departamento de Enfermería Facultad de Ciencias de la SaludUniversidad de GranadaGranadaSpain Departamento de Neurología Hospital Virgen de las NievesGranadaSpain Departamento de Neurología Hospital Virgen de ValmeSevillaSpain centro de Salud Utrera Sur SevillaSpain centro de Salud Polígono Sur SevillaSpain Unidad de Trastornos del movimiento Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain Departamento de medicina Facultad de MedicinaUniversidad de SevillaSevilleSpain Departamento de Antropología Social Universidad de GranadaSpain Unidad Enfermedades Neuromusculares Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain

In recent years,the number of known disease genes has exponentially grown due to the widespread adoption of cost-effective massive parallel *** identify new disease variants,especially in monogenic.disorders,a frequen... 详细信息

关键词： Server filtering massive

Advancements in Fixed Point Theorems for α-Geraghty contractions in complete metric Space

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Journal of mathematical Research with Applications 2024年第5期 697-710页

作者： V.c.BORKAR mohammed m.A.TALEB Saeed A.A.AL-SALEHI School of mathematical at Yeshwant mahavidyalaya Swami Ramanand Teerth Marathwada University School of mathematical at Science college Swami Ramanand Teerth Marathwada University Department of mathematics Hodeidah University Department of mathematics Aden University

This article improves and advances the results achieved by Vishal and Naveen, leveraging the use of Lebesgue integrable functions. Going beyond, we investigate fixed point theorems associated with a concept introduced by Ovidiu Popescu. Our research not only bolsters the theoretical framework but also unveils practical applications in the domain of Lebesgue integrals as in Example 3.6. Furthermore, our contribution enhances the understanding of fixed point theorems in metric spaces and introduces novel perspectives in the study of generalized α-Geraghty contractive mappings on Lebesgue integrals.

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Refractory Ventricular Fibrillation with Underlying coronary Artery Disease after cOVID-19 Vaccine-Kounis Syndrome or coincidence

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case Reports in clinic.l medicine 2024年第8期13卷 309-314页

作者： Elaine m. c. chau cardiology centre Hong Kong Sanatorium & Hospital Hong Kong SAR China

A 63-year-old man with diabetes and asymptomatic coronary artery disease developed refractory ventricular arrhythmia at 20 hours at rest after his second cOVID-19 vaccine. Despite significant stenosis in the coronary arteries, there was no evidence of acute or old myocardial infarction, heart failure, myocarditis or structural abnormalities on post-mortem to account for the substrate for the fatal arrhythmia. The refractory and incessant nature of the ventricular fibrillation and post-mortem finding of a grossly elevated unexplained IgE level (in the absence of acute myocardial infarction) suggested the possibility of Kounis Syndrome or allergic acute coronary syndrome.

关键词： Refractory Ventricular Fibrillation cOVID-19 Vaccine Kounis Syndrome

Adaptive marine Predator Optimization Algorithm(AOmA)-Deep Supervised Learning classification(DSLc)based IDS framework for mANET security

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Intelligent and converged Networks 2024年第1期5卷 1-18页

作者： m.Sahaya Sheela A.Gnana Soundari Aditya mudigonda c.Kalpana K.Suresh K.Somasundaram Yousef Farhaoui Department of Electronic. and communic.tion Engineering Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and TechnologyChennai 600069India Department of computer Science and Engineering Saveetha School of EngineeringSIMATSChennai 602105India JNIAS School of Planning and Architecture Hyderabad 500034India Department of computer Science and Engineering NPR College of Engineering and TechnologyNatham Dindigul 624401India Department of computer Science and Engineering PSNA College of Engineering and TechnologyPoolangulathupatti 620009India Department of computer Science and Engineering Sri Muthukumaran Institute of TechnologyChennai 600069India Department of computer Science Moulay Ismail UniversityMeknes 5003Morocco

Due to the dynamic nature and node mobility,assuring the security of mobile Ad-hoc Networks(mANET)is one of the difficult and challenging tasks *** mANET,the Intrusion Detection System(IDS)is crucial because it aids in the identification and detection of malicious attacks that impair the network’s regular *** machine learning and deep learning methodologies are used for this purpose in the conventional works to ensure increased security of ***,it still has significant flaws,including increased algorithmic complexity,lower system performance,and a higher rate of ***,the goal of this paper is to create an intelligent IDS framework for significantly enhancing mANET security through the use of deep learning ***,the min-max normalization model is applied to preprocess the given cyber-attack datasets for normalizing the attributes or fields,which increases the overall intrusion detection performance of ***,a novel Adaptive marine Predator Optimization Algorithm(AOmA)is implemented to choose the optimal features for improving the speed and intrusion detection performance of ***,the Deep Supervise Learning classification(DSLc)mechanism is utilized to predict and categorize the type of intrusion based on proper learning and training *** evaluation,the performance and results of the proposed AOmA-DSLc based IDS methodology is validated and compared using various performance measures and benchmarking datasets.

关键词： Intrusion Detection System(IDS) Security mobile Ad-hoc Network(mANET) min-max normalization Adaptive marine Predator Optimization Algorithm(AOmA) Deep Supervise Learning classification(DSLc)