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curcumin-Loaded Electrospun Fibers: Fluorescence and Antibacterial Activity

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Advanced Fiber materials 2020年第5期2卷 256-264页

作者： mário césar Albuquerque de oliveira Fernando Antonio Gomes da Silva Jr. mateus matiuzzi da costa Nikifor Rakov Helinando Pequeno de oliveira Institute of materials Science Federal University of Sao Francisco ValleyJuazeiroBA 48920-310Brazil

The health benefits and sensing applications of curcumin-based systems depend on their prevailing photophysical and chemi-cal properties at a specific environment-the characteristic low solubility of curcumin in water hinders high-dosage based *** circumvent this drawback,curcumin has been incorporated in hydrophobic environments in ***,electrospun fibers of Eudragit L100 were loaded with curcumin and applied in fluorescence and antibacterial assays to evaluate prevailing physical and chemical properties in *** characteristic high loading degree of curcumin(250 mg/mL in Eudragit L100 solution)preserves not only the photophysical properties of molecules(such as the intrinsic fluorescence)but also the antibacterial activity of released molecules from electrospun fibers,characterizing an important strategy for improvement in the applicability potential of natural materials.

关键词： curcumin Fluorescence Electrospinning Hydrophobic core

Ecophysiology and multivariate analysis for production of Tachigali vulgaris in Brazil:Influence of rainfall seasonality and fertilization

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Journal of Forestry Research 2023年第5期34卷 1289-1305页

作者： Pedro Henrique oliveira Simoes candido Ferreira.de oliveira Neto manoel Tavares de Paula Dênmora Gomes de Araújo Rodrigo Silva do Vale Joao Olegário Pereira.de carvalho Universidade Federal de mato Grosso Campus Universitario de SinopSinop 78550728Mato GrossoBrazil Universidade Federal Rural da Amazonia Campus BelemBelem 66077830ParaBrazil Universidade do Estado do Para Centro de Ciencias Naturais e TecnologiaBelem 66095015ParaBrazil Universidade Federal Rural da Amazonia Campus Capitao-PocoCapitao Poco 68650000ParaBrazil

Studies on fertilization management of species native to the Amazon for energy plantations contribute to the diversity of species use and reduce biological risk due to the excessive use of clones or hybrids of *** study evaluates the effect of precipitation seasonality and phosphorus and potassium fertilization on gas exchange in a Tachigali vulgaris *** levels of P(zero,65.2,130.4 kg ha^(-1))and three of K(zero,100.0,200.0 kg ha^(-1))were applied in a 3×3 factorial randomized block *** exchange measurements were conducted in April and November *** low rainfall,high irradiance period,photo synthetic rates were up to four times higher than in the high rainfall period,reaching 20.3μmol m^(-2)s^(-1)in the treatment with 130.4 g kg^(-1)of P and 100.0 g kg^(-1)of *** analysis and principal component analysis reduced the initial eight gas exchange variables to two and three principal components in periods of high and low rainfall,*** multivariate method used in this study readily identified variations in the variables as a function of rainfall,with high reliability in explaining the data set.

关键词： Photosynthesis rate Stomatal conductance Principal component analysis Factor analysis Tachigali vulgaris

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Behavior of wood basic density according to environmental variables

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Journal of Forestry Research 2022年第2期33卷 497-505页

作者： Gabriel marcos Vieira oliveira Josémárcio de mello carlos Rogério de mello JoséRoberto Soares Scolforo Eder Pereira miguel Thiago campos monteiro Brazil Institute of Agricultural and Forestry defense of Espírito Santo(IDAF) Av.Lourival Lugon Moulinnº300CentroJerônimo MonteiroES CEP:29.550-000Brazil department of Forestry Sciences Universidade Federal de Lavras-UFLACaixa Postal 3037LavrasMG CEP:37.200-000Brazil Engineering department Universidade Federal de Lavras-UFLACaixa Postal 3037LavrasMG CEP:37.200-000Brazil Forestry Engineering department Faculdade de TecnologiaUniversity of Brasilia-UnBCampus Universitário Darcy RibeiroCaixa Postal 4357Asa Norte-BrasíliaDF CEP:70910-900Brazil department of Forestry Engineering and Technology Universidade Federal do Paraná-UFPRAv.Pref.Lothário Meissner632Jardim BotânicoCuritibaPR CEP:80.210-170Brazil

The relationships between climate conditions and wood density in tropical forests are still poorly *** quantify spatial dependence of wood density in the state of minas Gerais(mG,Brazil),map spatial distribution of density,and correlate density with climate variables,we extracted data from the Forest Inventory of minas Gerais for 1988 trees scaled throughout the territory and measured wood density of discs removed from the *** variables were extracted from the database of the Ecological-Economic Zoning of minas *** spatial analysis,tree densities were measured at 44 georeferenced sampling *** data were subjected to exploratory analysis,variography,cross-validation,model selection,and ordinary *** relationships between wood density and environmental variables were calculated using dispersion matrices,linear correlation,and *** density proved to be highly spatially dependent,reaching a correlation of 96%,and was highly continuous over a distance of 228 *** distribution of wood density followed a continuous gradient of 514-659 kg m^(−3),enabling corre-lation with environment *** was correlated with mean annual precipitation(−0.57),temperature(0.63),and evapotranspiration(0.83).Geostatistical methods proved useful in predicting wood density in native tropical forests with different climate *** results confirmed the sensitivity of wood density to climate change,which could affect future carbon stock in forests.

关键词： Biomass climate variables Geostatistics Hardwood Forest inventory minas Gerais

Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration

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World Journal of Gastroenterology 2007年第22期13卷 3112-3116页

作者： José celso a.dengh césar Vivian Lopes Luiz Felipe Pereira.de Lima Juliano Rodrigues de oliveira Filadélfi o Venco Giulio cesare Santo José Luiz Pimenta módena Echoendoscopy and Pathology Units from 9 de Julho Hospital and Ribeiro Preto medical School-USP So Paulo Brazil

AIm： To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration （EUS-FNA） for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions.mETHODS： From January/1997 to december/2006, 611 patients with pancreatic tumors were subjected to EUSFNA. The final diagnosis was obtained either by surgery （356 cases） or after a mean clinical follow-up of 11.8 mo in the remaining patients.RESULTS： There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 （97.4%） cases. There were 352 （57.6%） malignancies and 259 （42.4%） benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67% of the lesions. Overall, the sensitivity, specificity, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4%, 99.2%, 99.3%, 77.2% and 87.2%. Specifically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8% ys 82.4%, 100% ys 98.4%, 100% vs 99%, 54.8% vs 74.1% and 83.1% vs 87.8%. For cystic lesions, the values were, respectively, 72.2%, 99.3%, 97.5%, 91% and 92.2%.cONcLUSION： EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions can reveal the best negative predictive value and diagnostic accuracy, both higher than 90%.

关键词： Diagnosis Endoscopic ultrasound Fineneedle-aspiration biopsy Pancreas cancer Pancreatic disease Sampling

Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis

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World Journal of Gastroenterology 2014年第28期20卷 9458-9467页

作者： Bruno césar da Silva Andre castro Lyra Raquel Rocha Genoile oliveira Santana Post-graduate Program in medicine and Health Federal University of Bahia Gastroenterology department of the University Hospital Professor Edgard Santos Federal University of Bahia Gastro-Hepatology Service of Hospital S?o Rafael department of Sciences of Nutrition School of NutritionFederal University of Bahia

Ulcerative colitis(Uc)is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and *** hallmark clinical symptom of Uc is bloody *** clinical course is marked by exacerbations and remissions,which may occur spontaneously or in response to treatment changes or intercurrent *** is most commonly diagnosed in late adolescence or early adulthood,but it can occur at any *** incidence of Uc has increased worldwide over recent decades,especially in developing *** contrast,during this period,therapeutic advances have improved the life expectancy of patients,and there has been a.decrease in the mortality rate over *** is important to emphasize that there is considerable variability in the phenotypic presentation of *** this context,certain clinical and demographic characteristics are useful in identifying patients who tend to have more severe evolution of the disease and a poor *** this group of patients,better clinical surveillance and more intensive therapy may change the natural course of the *** aim of this article was to review the epidemiology and demographic characteristics of Uc and the factors that may be associated with its clinical prognosis.

关键词： Ulcerative colitis Incidence Prevalence Risk factors Predictive factors

On the cauchy Problem describing an Electron-Phonon Interaction

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数学年刊（A辑） 2011年第4期32卷 I0001-I0004页

作者： Dias, João-Paulo Figueira, mário oliveira, Filipe centro de matemática e Aplicações Fundamentais and Faculdade de ciências Universidade de Lisboa Lisboa Portugal centro de matemática e Aplicações Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa Monte da Caparica Portugal

In this paper, a model is derived to describe a quartic anharmonic interatomic interaction with an external potential involving a pair electron-phonon. The authors study the corresponding cauchy Problem in the semilin... 详细信息

关键词：英文摘要内容介绍编辑工作期刊

Gut-microbiome-brain axis:the crosstalk between the vagus nerve,alpha-synuclein and the brain in Parkinson's disease

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Neural Regeneration Research 2023年第12期18卷 2611-2614页

作者： Júlio césar claudino dos Santos Leandro Freitas oliveira Felipe micelli Noleto camilla Teixeira Pinheiro Gusmão Gerly Anne de castro Brito Glauce Socorro de Barros Viana christus University center-UNIcHRISTUS FortalezaCEBrazil Postgraduate Program in morphofunctional Sciences Federal University of Ceará-UFCFortalezaCEBrazil Universidade católica.de Brasília-UcB BrasíliaDFBrasil Postgraduate Program in Physiology and Pharmacology department of the Federal University of ceará-UFc FortalezaCEBrazil Physiology and Pharmacology department of the Federal University of ceará-UFc FortalezaCEBrazil

This critical review of the literature shows that there is a close link between the microbiome,the gut,and the brain in Parkinson's *** vagus nerve,the main component of the parasympathetic nervous system,is involved in the regulation of immune response,digestion,heart rate,and control of *** can detect microbiota metabolites through its afferents,transferring this gut information to the central nervous *** and clinical studies have shown the important role played by the gut microbiome and gut-related factors in disease development and progression,as well as treatment *** findings suggest that the gut microbiome may be a valuable target for new therapeutic strategies for Parkinson's *** studies are needed to better understand the underlying biology and how this axis can be modulated for the patient's benefit.

关键词： alpha-synuclein enteric microbiota gastrointestinal tract Parkinson's disease vagus nerve

Habitat specialization and phylogenetic structure of tree species in a coastal Brazilian white-sand forest

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Journal of Plant Ecology 2014年第2期7卷 134-144页

作者： Alexandre a.de oliveira Alberto Vicentini Jerome chave camila.de T.castanho Stuart J.Davies Adriana m.Z.martini Renato A.F.Lima Ricardo R.Ribeiro Amaia Iribar Vinicius c.Souza Instituto de Biociências Universidade de São PauloRua do Matão321Travessa 14São PauloSP 0550890Brazil Instituto Nacional de Pesquisas da Amazônia Av.AndréAraújo2936CP 478.ManausAM 69060001Brazil Evolution et DiversitéBiologique Bâtiment 4R1 UniversitéPaul Sabatier118 route de Narbonne31062 ToulouseFrance Smithsonian Tropical Research Institute PO Box 37012WashingtonDC 20013-7012USA ESALQ Universidade de São Paulo.Avenida Pádua Dias11PiracicabaSP 13418900Brazil

Aims The coastal Brazilian rainforest on white-sand(restinga)ranks among the most fragmented forest types in the tropics,owing to both the patchy distribution of sandy soils and widespread coastal development *** we study the environmental and evolutionary determinants of a forest tree assemblage at a single restinga forest in Southeastern *** also explore the ability of competing hypotheses to explain the maintenance of species diversity in this forest type,which includes contrasting extremes of edaphic conditions associated with flooding *** The study was conducted in a white-sand forest permanent plot of 10.24 ha on the coastal plain of Southeastern *** plot was divided into 256 quadrats of 20×20 m,which were classified into two main edaphic habitats(flooded and drained).Trees with a diameter≥1 cm at breast height were *** assembled DNA sequence data for each of the 116 morphospecies recognized using two chloroplast markers(rbcL and matK).A phylogenetic tree was obtained using the maximum likelihood method,and a phylogenetic distance matrix was produced from an ultrametric *** analyzed similarity in floristic composition and structure between habitats and related them to cross-plot distances using permutation *** model torus shift simulations were performed to obtain a statistical significance level for habitat association for each *** phylogenetic structure for the two habitats and for each 20×20 m quadrat was calculated using the mean phylogenetic distance weighted by species abundance and checked for significance using the standardized effect size generated by 5000 randomizations of phylogenetic tip *** Findings Our results indicate that partitioning among edaphic habitats is important for explaining species distributions and coexistence in restinga *** distributions within the plot were found to be non-random:there was greater floristic similarity within than betwe

关键词： habitat association torus-translation test phylogenetic community structure niche partitioning edaphic condition

In vivo study of conductive 3D printed PcL/mWcNTs scaffolds with electrical stimulation for bone tissue engineering

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Bio-design and manufacturing 2021年第2期4卷 190-202页

作者： Edney P.e Silva Boyang Huang Júlia V.Helaehil Paulo R.L.Nalesso Leonardo Bagne maraiara a.de oliveira Gabriela c.c.Albiazetti Ali Aldalbahi mohamed El-Newehy milton Santamaria-Jr Fernanda A.S.mendonça Paulo Bártolo Guilherme F.caetano Postgraduate Program in Biomedical Sciences University Center of Hermínio Ometto Foundation-FHOArarasSao PauloBrazil department of mechanical Aerospace and Civil EngineeringSchool of EngineeringUniversity of ManchesterManchester M139PLUK King Abdullah Institute for Nanotechnology King Saud UniversityRiyadh 11451Saudi Arabia

critical bone defects are considered one of the major clinical challenges in reconstructive bone *** combination of 3D printed conductive scaffolds and exogenous electrical stimulation(ES)is a potential favorable approach for bone tissue *** this study,3D conductive scaffolds made with biocompatible and biodegradable polycaprolactone(PcL)and multi-walled carbon nanotubes(mWcNTs)were produced using the extrusion-based additive manufacturing to treat large calvary bone defects in *** results show that the use of PcL/mWcNTs scaffolds and ES contributes to thicker and increased bone tissue formation within the bone *** and mineralization are also significantly promoted using high concentration of mWcNTs(3 wt%)and ***,scaffolds favor the tartrate-resistant acid phosphatase(TRAP)positive cell formation,while the addition of mWcNTs seems to inhibit the osteoclastogenesis but present limited effects on the osteoclast functionalities(receptor activator of nuclear factor κβ ligand(RANKL)and osteoprotegerin(OPG)expressions).The use of ES promotes the osteoclastogenesis and RANKL expressions,showing a dominant effect in the bone remodeling *** results indicate that the combination of 3D printed conductive PcL/mWcNTs scaffold and ES is a promising strategy to treat critical bone defects and provide a cue to establish an optimal protocol to use conductive scaffolds and ES for bone tissue engineering.

关键词： Additive manufacturing Bone regeneration Bone remodeling carbon nanotube conductive scaffolds Electrical stimulation