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Transfusion transmitted virus: A review on its molecular characteristics and role in medicine

World Journal of Gastroenterology 2006年第32期12卷 5122-5134页

作者： m irshad YK Joshi Y Sharma I Dhar Clinical Biochemistry Division Department of Laboratory medicine All India Institute of Medical SciencesNew Delhi-110029India Department of Gastroenterology and Human Nutrition All India Institute of medical Sciences New Delhi-110029India

The present review gives an updated overview of transfusion transmitted virus （TTV）, a novel agent, in relation to its molecular characteristics, epidemiological features, modes of transmission, tissue tropism, pathogenesis, role in various diseases and its eradication from the body. TTV, a DNA virus, is a single stranded, non-enveloped, 3.8 kb long DNA virus with a small and covalently closed circular genome comprising 3852 bases. It was tentatively designated Cirdnoviridae *** genome sequence is heterogeneous and reveals the existence of six different genotypes and several subtypes. TTV has been reported to transmit not only via parenteral routes, but also via alternate routes. This virus has been detected in different non-human primates as well. At present, TTV is detected by polymerase chain reaction （PCR） with no other available diagnostic assays. It shows its presence globally and was detected in high percent populations of healthy persons as well as in various disease groups. Initially it was supposed to have strong association with liver disease; however, there is little evidence to show its liver tropism and contribution in causing liver diseases. It shows high prevalence in hemodialysis patients, pointing towards its significance in renal diseases. In addition,TTV is associated with several infectious and non-infectious diseases. Though, its exact pathogenesis is not yet clear, TTV virus possibly resides and multiplies in bone marrow cells and peripheral blood mononuclear cells （PBmCs）. Recently, attempts have been made to eradicate this virus with interferon treatment. more information is still needed to extricate various mysteries related to TTV.

关键词： Transfusion transmitted virus DNA Virus Hepatitis Transfusion

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Transfusion-transmitted virus in association with hepatitis A-E viral infections in various forms of liver diseases in India

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World Journal of Gastroenterology 2006年第15期12卷 2432-2436页

作者： m irshad Y Sharma I Dhar J Singh YK Joshi Clinical Biochemistry Division Department of Laboratory medicine All India Institute of Medical SciencesAnsari NagarNew Delhi 110029India Department of Gastroenterology & Human Nutrition Unit All India Institute of medical Sciences Ansari NagarNew Delhi-110029India

AIm： To describe the prevalence of transfusiontransmitted virus （TTV） infection in association with hepatitis A-E viral infections in different forms of liver diseases in North India. mETHODS： Sera from a total number of 137 patients, including 37 patients with acute viral hepatitis （AVH）, 37 patients with chronic viral hepatitis （CVH）, 31 patients with cirrhosis of liver and 32 patients with fulminant hepatic failure （FHF）, were analyzed both for TTV-DNA and hepatitis A-E viral markers. Presence of hepatitis B virus （HBV）, hepatitis C virus （HCV） and hepatitis E virus （HEV） infections was detected in different proportions in different groups. moreover, rrV-DNA was simultaneously tested in 100 healthy blood donors also. RESULTS： None of the patients had hepatitis A virus （HAV） and hepatitis D virus （HDV） infections. Overall prevalence of TTV-DNA was detected in 27.1% cases with AVH, 18.9% cases with CVH, 48.4% cases with cirrhosis and 9.4% cases with FHF. TTV-DNA simultaneously tested in 100 healthy blood donors showed 27% positivity. On establishing a relation between TTV infection with other hepatitis viral infections, TTV demonstrated co-infection with HBV, HCV and HEV in these disease groups. Correlation of TTV with ALT level in sera did not demonstrate high ALT level in TTV-infected patients, suggesting that TI-V does not cause severe liver damage. CONCLUSION： TTV infection is prevalent both in patients and healthy individuals in India. However, it does not have any significant correlation with other hepatitis viral infections, nor does it produce an evidence of severe liver damage in patients with liver diseases.

关键词： Transfusion-transmitted virus HCV hepatitis AVH

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弓形块隧道衬砌

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隧道译丛 1991年第4期 53-55页

作者： irshad,m 徐继源

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Yield and Quality of Forage Oat (<i>Avena sativa</i>L.) Cultivars as Affected by Seed Inoculation with Nitrogenous Strains

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American Journal of Plant Sciences 2015年第19期6卷 3251-3259页

作者： muhammad Saleem m. Shahid Ibni Zamir Ihtishamul Haq m. Zahid irshad m. Kamran Khan m. Asim Qamaruz Zaman Ihtisham Ali Aman Khan Saeedur Rehman Department of Agronomy University of Agriculture Faisalabad Pakistan

Nitrogen availability can be enhanced with the application of nitrogen fixing bacteria and it may be helpful in increasing forage yield and improving quality of oat. Therefore, a field trial to evaluate the effect of seed inoculation with nitrogen fixing bacteria on forage yield and quality of oat was carried out at Agronomic Research Area, University of Agriculture, Faisalabad during Rabi season 2013-14. The experiment was laid out in Randomized Complete Block Design (RCBD) with factorial arrangements using three replications. The experiment was comprised of two integrated approaches. The first approach was oat cultivars consisting of four treatments, V1 (AVON), V2 (S-2000), V3 (S-2011) and V4 (PD2LV65) and the second approach was seed inoculation consisting of three treatments, S0 (control), S1 (Azotobacter spp.), S2 (Azospirillum spp.). Fisher’s analysis of variance technique was used for statistically interpretation of data by using least significant difference (LSD) test at 5% level of probability. Nitrogen fixing bacteria significantly affect the germination count (m2), plant height (cm), number of tillers (m2), number of leaves per tiller, leaf area per tiller (cm2), green forage yield (t·ha-1) and dry matter yield (t ha-1). The maximum green forage yield (85.2 t·ha-1), dry matter yield (14.1 t ·ha-1) and crude protein (11.5%) were recorded where Azotobacter inoculation was applied. The interaction between cultivars and nitrogenous strains was significant for green forage yield (t·ha-1), dry matter yield (t·ha-1) and crude protein (%). Conclusion showed that cultivar Sargodha-2011 which was inoculated with Azotobacter spp. gave higher forage yield of good quality.

关键词： Oat Cultivars Nitrogenous Strains Quality and Forage Yield

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Toxicological and Life-Cycle Perspectives on Waste-Derived Nanoparticles

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Journal of materials Science and Chemical Engineering 2024年第8期12卷 43-68页

作者： irshad Ahmad md Fahimul Hassan Weqar Ahmad Siddiqui Department of Applied Science & Humanities Faculty of Engineering & Technology Jamia Millia Islamia University New Delhi India Department of Chemistry C.M. Science College Lalit Narayan Mithila University Darbhanga India

many nanoparticles have been created over the last few decades using a variety of techniques and used to develop environmental technology, including water treatment, the detection of persistent contaminants, and soil and water remediation. The studies of alternative inputs for nanoparticle production as well as the use of green synthesis techniques are driven by the field of materials science and engineering’s growing interest in increasing the sustainability of the processes involved in their production. In this paper, we begin by providing an overview of the fundamental principles of producing nanoparticles from different sources, such as plastic, electronic, metal, and industrial waste. We elaborate on key facts of waste identification as a workable input for the treatment and recovery of metal and carbon-based nanoparticles. We next go over several controlling factors that play a role in creating nanoparticles, pointing out probable conclusions as we go. Then, we show some instances of waste-derived nanoparticles used in a proof-of-concept experiment of technology for applications in water quality and safety. Before scaling up production and implementing waste-derived nanoparticles, there are several present problems from the toxicological and life-cycle perspectives that must be taken into account.

关键词： Industrial Waste Plastic Trash metal Waste Carbon Nanoparticles Nanoparticle-Enabled Technologies Electronic-Waste

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Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese Physics C 2024年第8期48卷 6-33页

作者： m.Ablikim m.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya K.Begzsuren N.Berger m.Berlowski m.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen m.L.Chen S.J.Chen S.L.Chen S.m.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.K.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko m.Destefanis F.De mori B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng K.Fischer m.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge Z.W.Ge C.Geng E.m.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong m.Y.Dong X.Dong m.C.Du S.X.Du Z.H.Duan P.Egorov Y.H.Fan J.Fang JA.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna m.Greco m.H.Gu Y.T.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo m.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez K.L.Han T.T.Han X.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold T.Holtmann P.C.Hong G.Y.Hou X.T.Hou Y.R.Hou Z.L.Hou B.Y.Hu H.m.Hu J.F.Hu T.Hu Y.Hu G.S.Huang K.X.Huang L.Q.Huang X.T.Huang Y.P.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche m.irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang H.B.Jiang P.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin m.Q.Jing X.m.Jing T.Johansson S.Kabana N.Kalantar-Nayestanaki X.L.Kang X.S.Kang m.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf m.Kuessner X.Kui A.Kupsc W.K\"uhn J.J.Lane P.Larin L.Lavezzi T.T.Lei Z.H.Lei H.Leithoff m.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.m.Li F.Li G.Li H.Li H.B.Li H.J.Li H.N.Li Hui Li J.R.Li J.S.Li K.Li L.J.Li L.K.Li Lei Li m.H.Li P.R.Li Q.m.Li Q.X.Li R.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Y.Li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner mongolia University Hohhot 010021China Institute of modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKm angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis CP-even fraction

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Energy Efficient Green Routing for UAVs Ad-Hoc Network

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Intelligent Automation & Soft Computing 2023年第7期37卷 1111-1127页

作者： m.muthukumar Rajasekar Rangasamy irshad Hussain Salman A.AlQahtani Department of Computer Science and Engineering Sree Sowdambika College of EngineeringTamil NaduIndia Department of Computer Science and Engineering-AI&mL School of EngineeringMalla Reddy UniversityHyderabadIndia Faculty of Electrical and Computer Engineering University of Engineering and Technology Peshawar25000PeshawarPakistan Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Kingdom of Saudi Arabia

The purpose of this article is to propose Stability-based Energy-Efficient Link-State Hybrid Routing(S-ELHR),a low latency routing proto-col that aims to provide a stable mechanism for routing in unmanned aerial vehicles(UAV).The S-ELHR protocol selects a number of network nodes to create a Connected Dominating Set(CDS)using a parameter known as the Stability metric(Sm).The Sm considers the node’s energy usage,connectivity time,and node’s *** the highest Sm nodes are chosen to form *** node declares a Willingness to indicate that it is prepared to serve as a relay for its neighbors,by employing its own energy state.S-ELHR is a hybrid protocol that stores only partial topological information and routing tables on CDS *** of relying on the routing information at each intermediary node,it uses source routing,in which a route is generated on-demand,and data packets contain the addresses of the nodes the packet will transit.A route recovery technique is additionally utilized,which first locates a new route to the destination before forwarding packets along *** simulation for various network sizes and mobility speeds,the efficiency of S-ELHR is *** findings demonstrate that S-ELHR performs better than Optimized Link State Routing(OLSR)and Energy Enhanced OLSR(EE-OLSR)in terms of packet delivery ratio,end-to-end delay,and energy consumption.

关键词： Connected dominatingset hybridrouting UAVAdhocnetworks link state stability

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Kaempferol and its derivatives:Biological activities and therapeutic potential

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Asian Pacific Journal of Tropical Biomedicine 2023年第10期13卷 411-420页

作者： Shazia Parveen irshad Ul Haq Bhat Rajeev Bhat Chemistry Department Faculty of ScienceTaibah UniversityYanbu BranchYanbu-46423Saudi Arabia Department of Chemistry College of ScienceUniversity of BahrainP.O.Box 32038Bahrain ERA-Chair for Food(By-)Products Valorisation Technologies Estonian University of Life SciencesTartu-510014EstoniaEU

Kaempferol,a natural plant-origin flavonoid,exhibits therapeutic anti-inflammatory,antioxidant,anticancer,antidiabetic,and neuroprotective *** acts within several distinct mechanisms like apoptotic induction in cancer cells,enzymatic inhibition,signalling pathway inhibition,and downregulation in cell viability during the G2/m phase of cell *** review summarizes the therapeutic effects of kaempferol against several health *** recent progress on kaempferol obtained from fruits and vegetables as an antioxidant,anti-inflammatory,anticancer,antidiabetic,and neuroprotective agent and its mechanisms of action are also *** addition,kaempferol has been reported to be present in wastes and byproducts from post-fruit and vegetable ***,a paradigm shift towards valorizing fruits and vegetable industrial wastes/byproducts to obtain bioactive kaempferol can support the circular economy pillar for generating wealth from waste and for finding a sustainable alternative source.

关键词： Kaempferol Therapeutic effects Bioactivities Fruits and vegetable wastes Sustainable alternative sources

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Data Reliability and Sensors Lifetime in Bridge Health monitoring using LoRaWAN-Zigbee

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Computers, materials & Continua 2022年第11期73卷 2663-2678页

作者： Awad Ali Reyazur Rashid irshad Ahmed Abdu Alattaab Aamir Fatahayab Department of Computer Science College of Science and Arts-SharourahNajran UniversityNajranKingdom of Saudi Arabia Department of Computer Science JJTUJhunjhunuRajasthanIndia

The Wireless Sensor Network(WSN)is regarded as the fastest expanding technological trend in recent years due its application in a variety of *** the monitoring region,several sensor nodes with various sensing capabilities are installed to gather appropriate data and communicate it to the *** proposed system of the heterogeneous WSN employing LoRaWAN-Zigbee based hybrid communication is explored in this research *** communicate in a network,two Long–Range Wide Area Network(LoRaWAN)sensor clusters and two Zigbee sensor clusters are employed,together with two Zigbee and LoRaWAN *** suggested Golden eagle shepherd optimization(GESO)method then forms Zigbee as well as LoRaWAN networking ***,depending on energy usage and data packet size,the fitness of each sensor node is assessed using the Dynamic Intelligent Reasoning Based Neural(DIRN)*** software is used to implement and execute this *** the Zigbee network’s transmission distance is 650 m and the LoRaWAN network’s transmission range is 3.5 km,the system can function with a packet loss rate of less than 0.04 *** study shows significant gains in the performance of the system when compared to traditional approaches based on digital findings obtained on software solutions.

关键词： Zigbee LoRaWAN wireless sensor network health monitoring routing protocol

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Data-Driven Approach for Condition monitoring and Improving Power Output of Photovoltaic Systems

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Computers, materials & Continua 2023年第3期74卷 5757-5776页

作者： Nebras m.Sobahi Ahteshamul Haque V S Bharath Kurukuru md.mottahir Alam Asif irshad Khan Department of Electrical and Computer Engineering(ECE) King Abdulaziz UniversityJeddah 21589Saudi Arabia Advance Power Electronics Research Lab Department of Electrical EngineeringJamia Millia IslamiaNew DelhiIndia Computer Science Department Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah 21589Saudi Arabia

Increasing renewable energy targets globally has raised the requirement for the efficient and profitable operation of solar photovoltaic(PV)*** light of this requirement,this paper provides a path for evaluating the operating condition and improving the power output of the PV system in a grid integrated *** achieve this,different types of faults in grid-connected PV systems(GCPVs)and their impact on the energy loss associated with the electrical network are analyzed.A data-driven approach using neural networks(NNs)is proposed to achieve root cause analysis and localize the fault to the component level in the *** localized fault condition is combined with a parallel operation of adaptive neurofuzzy inference units(ANFIUs)to develop a power mismatch-based control unit(PmCU)for improving the power output of the *** develop the proposed framework,a 10-kW single-phase GCPV is simulated for training the NN-based anomaly detection approach with 14 deviation ***,the developed algorithm is combined with the PmCU implemented with the experimental setup of *** results identified 98.2%training accuracy and 43000 observations/sec prediction speed for the trained classifier,and improved power output with reduced voltage and current harmonics for the grid-connected PV operation.

关键词： Condition monitoring anomaly detection performance evaluation fault classification optimization

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