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ImPROVEmENT OF DISPERSION ABILITY OF NANOmETER PARTICLES BY mEANS OF PLASmA POLYmERIZATION

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Acta metallurgica Sinica(English Letters) 2002年第1期15卷 73-76页

作者： G.Q. Zhang X.G. Guo Y.m. Liu Y.J. ge Beijing Inst. of Printing Beijing 102600 China

In order to find a new way to improve the dispersion ability of nanometer material, an investigation on preparation of thin film with low surface energy on the surface of nanometer material by means of plasma polymerization has been done. Some physical behaviors and chemical constitution of prepared film as well as the influence of polymerized film on nanometer material were tested. All the experimental results showed that this is a possible way to improve the dispersion ability of nanometer materials.

关键词： plasma polymerization nanometer material

A novel prognostic gene signature,nomogram and immune landscape based on tanshinone IIA drug targets for hepatocellular carcinoma:Comprehensive bioinformatics analysis and in vitro experiments

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BIOCELL 2023年第7期47卷 1519-1535页

作者： BOWEN PENG YUN ge GANG YIN School of Electronic Science and Engineering Nanjing UniversityNanjing210023China Department of Radiation Oncology Sichuan Cancer Hospital&InstituteChengdu610041China Radiation Oncology Key Laboratory of Sichuan Province Chengdu610041China

Tanshinone IIA,one of the main ingredients of Danshen,is used to treat hepatocellular carcinoma(HCC).However,potential targets of the molecule in the therapy of HCC are ***:In this study,we collected the tanshinone IIA targets from public databases for *** screened differentially expressed genes(DEGs)across HCC and normal tissues using mRNA expression profiles from The Cancer genome Atlas(TCGA).Univariate Cox regression analysis and least absolute shrinkage and selection operator(LASSO)Cox regression models were used to identify and construct the prognostic gene ***:Finally,we discovered common genes across tanshinone IIA targets and HCC *** reported Fatty acid binding protein-6(FABP6),Polo-like Kinase 1(PLK1),deoxythymidylate kinase(DTYmK),Uridine Cytidine Kinase 2(UCK2),Enhancer of Zeste Homolog 2(EZH2),and Cytochrome P4502C9(CYP2C9)as components of a gene *** six-gene signature’s prognostic ability was evaluated using the Kaplan-meier curve,time-dependent receiver operating characteristic(ROC),multivariate Cox regression analysis,and the *** mRNA level and protein expression of UCK2 were experimentally validated after treatment with different concentrations of tanshinone IIA in HEPG2 ***,TImER2.0,and gePIA2 tools were employed to explore the relationship between the prognostic signature and immune cell ***:We established a six-gene signature as a reliable model with significant therapeutic possibility for prognosis and overall survival estimation in HCC patients,which might also benefit medical decision-making for appropriate treatment.

关键词： Tanshinone IIA Hepatocellular carcinoma Immune cell infiltration Prognosis signatures

Characteristic analysis of clinical coronary heart disease and coronary artery disease concerning young and middle-aged male patients

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World Journal of Clinical Cases 2021年第25期9卷 7358-7364页

作者： Kai-ge Peng Hui-Lin Yu Department of Cardiovascular medicine Anqing Municipal HospitalAnqing 230032Anhui ProvinceChina

BACKGROUND Coronary heart disease(CHD)is a type of coronary atherosclerotic heart *** recent years,the incidence of CHD has been increasing annually,with an increasing number of young *** CHD may cause severe myocardial ischemia or myocardial necrosis,which in turn may cause myocardial infarction and related complications that seriously affect the life and health of the *** To examine the coronary arteries and clinical features of young and middle-aged male patients with *** From February 2019 to January 2020,110 male CHD patients admitted to our hospital were selected as research subjects and were divided into two groups by age:middle-aged group(n=55)and young group(n=55).The coronary arteries and clinical features of the patients were *** There were no significant differences in dyslipidemia,stroke history,high-density lipoprotein cholesterol,or triacylglycerol(P>0.05)between the two *** the young group,age,diabetes,hypertension,smoking history,body mass index,family history of CHD,drinking history,fibrinogen,low-density lipoprotein cholesterol,total cholesterol,and single-vessel disease were higher than those in the middle-aged ***,serum uric acid,hyperuricemia,myocardial infarction,gensini score>50,collateral circulation,multivessel disease,double vessel disease,involvement of the right coronary artery,and involvement of the left main coronary artery were lower in the young group than in the middle-aged *** middle-aged group mainly suffered from a high gensini score,implicating multiple arteries,whereas the young group was mainly affected by single-vessel *** between-group difference was significant(Pmultiple coronary arteries are implicated in middle-aged male patients and single-vessel disease in young male patients.

关键词： Coronary heart disease Coronary artery disease Coronary artery features myocardial ischemia Risk factors

Noncoding RNAs:Different roles in tumorigenesis

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Chinese Science Bulletin 2012年第9期57卷 959-965页

作者： LIN mei WU Jing SHAN ge School of Life Sciences University of Science and Technology of China Hefei 230026 China School of Life Science and Technology Huazhong University of Science and Technology Wuhan 430074 China

A major portion of the mammalian genome is transcribed to produce large numbers of noncoding RNAs(ncRNAs).During the past decade,the discovery of small RNAs,including the microRNAs(miRNA) and small interfering RNAs(siRNA),has led to important advances in *** breadth of the ncRNA field of study has substantially expanded and many recent results have revealed a range of functions that can be attributed to the miRNAs and other *** example,H19 RNA,HOTAIR RNA,transcribed ultraconserved regions(T-UCRs),natural antisense RNA,transfer RNA and mitochondrial noncoding RNA have been suggested to play important roles in cancers and other diseases as well as in diverse cellular *** this review,we focus on the current status of several classes of ncRNAs associated with cancer with the emphasis on those that are not microRNAs.

关键词：非编码RNA 小分子RNA miRNAs RNA干扰肿瘤反义RNA 哺乳动物核糖核酸

Large Deformation Beam/Cable Element with Implicit Kinematic model

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Journal of Harbin Institute of Technology(New Series) 2013年第6期20卷 1-8页

作者： Shi-Yi Liu Yao-Jun ge State Key Laboratory of Disaster Reduction in Civil Engineering Tongji University

This paper proposes a 3D 2-node element for beams and cables. main improvements of the element are two new interpolation functions for beam axis and cross-sectional rotation. New interpolation functions employ implicit functions to simulate large deformations. In the translational interpolation function, two parameters which affect lateral deflection geometry are defined implicitly through nonlinear equations. The proposed translational interpolation function is shown to be more accurate than Hermitian function at large deformations. In the rotational interpolation function, twist rate is defined implicitly through a torsional continuity equation. Cross-sectional rotation which is strictly consistent to beam axis is obtained through separate bending rotation interpolation and torsional rotation interpolation. The element model fully accounts for geometric nonlinearities and coupling effects,and thus,can simulate cables with zero bending stiffness. Stiffness matrix and load vector have been derived using symbolic computation. Source code has been generated *** examples show that the proposed element has significantly higher accuracy than conventional 2-node beam elements under the same meshes for geometrically nonlinear problems.

关键词： large deformation analysis 2-node interpolation functions consistent rotational interpolation implicit functions symbolic computationCLC number:TU323.3 Document code:AArticle ID:1005-9113(2013)06-0001-08

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激光散射告警中的被照射目标判断方法研究

电光与控制 2024年第10期31卷 106-110页

作者：张启鹏葛启东杨昱钱苏敏亓统帅中国人民解放军63893部队河南洛阳471000

对激光散射信号进行探测是一种常用的激光告警方式,但这种方式不能判断告警范围内不同的被照射目标。为了实现激光散射告警中对不同被照射目标的判断,研究了激光从各个方向对目标照射时,告警装置各个窗口的告警响应情况,分析了不同目标... 详细信息

对激光散射信号进行探测是一种常用的激光告警方式,但这种方式不能判断告警范围内不同的被照射目标。为了实现激光散射告警中对不同被照射目标的判断,研究了激光从各个方向对目标照射时,告警装置各个窗口的告警响应情况,分析了不同目标位置给告警结果带来的差异程度,提出通过告警装置各个窗口告警结果的告警编码和脉冲时序判断被照射目标的方法。研究结果表明,该方法可以区分相对告警装置夹角不小于72°、与告警装置均相距50 m的两个目标,在360°范围内可以对符合规定要求的5个目标实现判别。研究结果为增强散射探测型激光告警装置的告警能力、提高后续防护的针对性和效率提供了技术参考。

关键词：激光告警大气散射告警编码被照射目标判断

Dynamic evolution of vortex structures induced bytri-electrode plasma actuator

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Chinese Physics B 2020年第2期29卷 337-345页

作者： Bo-Rui Zheng ming Xue Chang ge School of Automation and Information Engineering Xi'an University of TechnologyXi'an 710048China Department of Aeronautics and Astronautics Northwestern Polytechnical UniversityXi'an 710072China

Plasma flow control is a new type of active flow control approach based on plasma pneumatic *** barrier discharge(DBD) actuators have become a focus of international aerodynamic ***,the practical applications of typical DBDs are largely restricted due to their limited discharge area and low relative-induced *** further improvement of performance will be beneficial for engineering *** this paper,high-speed schlieren and high-speed particle image velocimetry(PIV) are employed to study the flow field induced by three kinds of plasma actuations in a static atmosphere,and the differences in induced flow field structure among typical DBD,extended DBD(EX-DBD),and tri-electrode sliding discharge(TED) are *** analyzing of the dynamic evolution of the maximum horizontal velocity over time,the velocity profile at a fixed horizontal position,and the momentum and body force in a control volume reveals that the induced velocity peak value and profile velocity height of EX-DBD are higher than those of the other two types of actuation,suggesting that EX-DBD actuation has the strongest temporal aerodynamic effect among the three types of *** TED actuation not only can enlarge the plasma extension but also has the longest duration in the entire pulsed period and the greatest influence on the height and width of the airflow near the wall ***,the TED actuation has the ability to continuously influencing a larger three-dimensional space above the surface of the nlasma actuator.

关键词： plasma flow control dielectric barrier discharge vortex dynamics tri-electrode sliding discharge

Persuasive Technology for the Future of Smoking Cessation^*

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Advances in Internet of Things 2024年第2期14卷 36-52页

作者： Fatimah Dera m. Alshahrani College of Computer Science King Khalid University (KKU) Abha KSA

This paper explores the integration of persuasive technology into smoking cessation efforts through the development and evaluation of a mobile app, “No-Smoke.” Leveraging compelling features like social support, tracking, planning, and motivation, the app aims to augment user engagement and support the process of quitting smoking. The efficacy of these features has been substantiated through both automated testing and user feedback, highlighting their potential to enhance awareness, motivation, and behavior modification. Despite notable successes, limitations, including a limited user base and uncertainties regarding long-term efficacy, have been acknowledged, stemming from the inherent complexities of smoking cessation. Nevertheless, based on user experiences and feedback, “No-Smoke” represents a promising advancement in the use of technology for public health interventions, particularly in the realm of smoking cessation. To address existing challenges, future research is recommended to encompass a comprehensive, long-term study involving a larger and more diverse user base. Additionally, further investigation should focus on personalization enhancements and the integration of machine learning algorithms to better understand and respond to user behavior.

关键词： Persuasive Technology Smoking Cessation mobile App

Influence of span-to-depth ratio on dynamic response of vehicle-turnoutbridge system in high-speed railway

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High-Speed Railway 2024年第1期2卷 30-41页

作者： Chuanqing Dai Tao Xin Shenlu Qiao Yanan Zhang Pengsong Wang mahantesh m.Nadakatti School of Civil Engineering Beijing Jiaotong UniversityBeijing 100044China China Railway Engineering Design and Consulting Group Co. Ltd.Beijing 100070China Karnatak Law Society’s Gogte Institute of Technology Belagavi 590006India

For high-speed railways,the smoothness of the railway line significantly affects the operational speed of *** the train passes through the turnout on a long-span bridge,the wheel-rail impacts caused by the turnout structure irregularities,and the instability arising from the bridge's flexural deformation lead to a strong coupling effect in the vehicle-turnout-bridge *** significantly affects both ride comfort and operational *** addressing this issue,the present study considered a long-span continuous rigid-frame bridge as an example and established a train-turnout-bridge coupled dynamic model of high-speed *** a selfdeveloped dynamic simulation program,the study analysed the dynamic response characteristics when the train passes through the turnouts on the *** also investigated the influence of different span-to-depth ratios of the bridge on the vehicle dynamic response when the train passes through the main line and branch line of turnouts and then proposed a span-to-depth ratio limit value for a long-span continuous rigid-frame *** research findings suggest that the changes in the span-to-depth ratio have a relatively minor impact on the train’s operational performance but significantly affect the dynamic characteristics of the bridge *** on the findings and a comprehensive assessment of safety indicators,it is advisable to establish a span-to-depth ratio limit of 1/4500 for a long-span continuous rigid-frame bridge.

关键词： Turnout on bridge Span-to-depth ratio Dynamic response Vehicle-turnout-bridge system High-speed railway