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recent advances on phylogenomics of gymnosperms and a new classification

Plant Diversity 2022年第4期44卷 340-350页

作者： Yong Yang David Kay ferguson Bing Liu Kang-Shan Mao Lian-Ming Gao Shou-Zhou Zhang Tao Wan Keith rushforth Zhi-Xiang Zhang Co-Innovation Center for Sustainable Forestry in Southern China College of Biology and the Environment159 Longpan RoadNanjing Forestry UniversityNanjing 210037China Department of Paleontology University of Vienna1090 ViennaAustria State Key Laboratory of Systematic and Evolutionary Botany Institute of BotanyChinese Academy of Sciences20 NanxincunXiangshanBeijing 100093China Sino-Africa Joint research Center Chinese Academy of SciencesWuhan 430074China Key Laboratory of Bio-resource and Eco-Environment of Ministry of Education College of Life SciencesState Key Laboratory of Hydraulics and Mountain River EngineeringSichuan UniversityChengdu 610065China CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Lijiang Forest Biodiversity National Observation and research Station Kunming Institute of BotanyChinese Academy of SciencesLijiang 674100China Key Laboratory of Southern Subtropical Plant Diversity FairyLake Botanical GardenShenzhen&Chinese Academy of SciencesShenzhenChina The Shippen AshillCullomptonDevonEN153NLUK School of Ecology and Nature Conservation Beijing Forestry UniversityBeijingChina

Living gymnosperms comprise four major groups:cycads,Ginkgo,conifers,and *** among/within these lineages have not been fully *** generation sequencing has made available a large number of sequences,including both plastomes and single-copy nuclear genes,for reconstruction of solid phylogenetic *** advances in gymnosperm phylogenomic studies have updated our knowledge of gymnosperm ***,we review major advances of gymnosperm phylogeny over the past 10 years and propose an updated classification of extant *** new classification includes three classes(Cycadopsida,Ginkgoopsida,and Pinopsida),five subclasses(Cycadidae,Ginkgoidae,Cupressidae,Pinidae,and Gnetidae),eight orders(Cycadales,Ginkgoales,Araucariales,Cupressales,Pinales,Ephedrales,Gnetales,and Welwitschiales),13 families,and 86 *** also described six new tribes including Acmopyleae ***,Austrocedreae ***,Chamaecyparideae ***,Microcachrydeae ***,Papuacedreae ***,and Prumnopityeae ***,and made 27 new combinations in the genus Sabina.

关键词： Classification Gymnosperms Morphology New tribe Phylogenomics Taxonomy

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Augmented efficacy of exogenous extracellular vesicles targeted to injured kidneys

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Signal Transduction and Targeted Therapy 2020年第1期5卷 817-819页

作者： Xiao-Jun Chen Kai Jiang Christopher M.ferguson Hui Tang Xiangyang Zhu Amir Lerman Lilach O.Lerman Division of Nephrology and Hypertension Mayo ClinicRochesterMNUSA Department of Nephrology The Second Xiangya Hospital of Central South UniversityChangshaHunanChina Department of Cardiovascular Diseases Mayo ClinicRochesterMNUSA

Dear Editor,Extracellular vesicles(EVs)derived from mesenchymal stem/stromal cells(MSCs)contain genetic and protein material that stimulate tissue repair and ameliorate injury in recipient *** of particulate MSC-EVs over MSCs in treating kidney disease include better penetration of injured glomerular filtration barrier to access podocytes or tubular ***,systemic EV delivery yields low kidney retention efficiency,limiting their regenerative benefits.1 Previously,we coated adipose tissue-derived(AD)-MSC with antibodies against kidney injury molecule(KIM)‐1(ab-KIM1),a protein upregulated in damaged kidneys.2 Conjugating ab-KIM1 did not impair MSC function but increased their retention and reparative potency in murine renal artery stenosis(rAS).2 We hypothesized that ab-KIM1 conjugation would similarly enhance retention of exogenously delivered EVs in ischemic kidneys and confer superior therapeutic benefits.

关键词： kidney retention sized

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State and Status of rTCM SC-104 Standards as related to the BeiDou Constellation

State and Status of RTCM SC-104 Standards as Related to the ...

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第五届中国卫星导航学术年会

作者： Kendall ferguson Hemisphere GNSS Inc.

The radio Technical Commission for Maritime Services （rTCM）, founded in 1947 as a U. S. State Department advisory committee, has been producing standards and recommendations related to all aspects of maritime radio navigation. Today rTCM is an independent non-profit organization which produces standards and recommendations that are used internationally and many of which are incorporated as either a basis of requirements by other international standards organizations and many of which are incorporated into government policy and law. The main work of standards development within rTCM occurs within their Special Committees （SC）. One such Special Committee （i.e., SC-104） focuses on Differential Global Navigation Satellite Systems （DGNSS）, which includes GPS, BeiDou, GLONASS, Galileo, QZSS, and others. In its early days, the main emphasis of SC-104 was on the now famed code based Differential GPS （DGPS） standard which is still in use throughout the world for Safety Of Life At Sea （SOLAS） applications. The standards produced by SC-104 were so successful that the committee was asked to address more non-maritime and non-SOLAS related applications and to include other constellations. Today, standards and recommendations produced by rTCM include not only SOLAS maritime, but many applications ranging from codephase based differential corrections through the high-accuracy multi-constellation/multi-frequency carrier based services （such as real-Time Kinematic （rTK）, Network rTK, Transformations, Precise Point Positioning （PPP）, and the Network Transport of rTCM via Internet （Ntrip））. recently, SC-104 has been actively adding to its standards the new constellations, such as BeiDou, and new signals, including many that are planned. This paper will discuss the plans and challenges to introduce BeiDou into rTCM DGNSS standards. This paper will also provide a brief history of rTCM SC-104, its current activities, and its work in progress.

关键词： DGNSS rTCM SC-104 Ntrip rTK BeiDou GPS Galileo GLONASS QZSS Standards Correction.

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INSTrUCTION IN THE FUNDAMENTAL SCIENCES A BrIEF rEVIEW OF THE PrESENT SITUATION IN CHINA

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Chinese Medical Journal 1935年第9期49卷 955-956页

作者： MArY E. ferguson registrar Peiping Union Medical College

Those connected with the Committee on Admissions of any medical school are primarily interested, when examining the credentials of candidates for admission, in the amount of instruction the individual student has already received in the fundamental sciences, chemistry, physics and biology, and in the quality of that instruction. Fifteen years ago the number of institutions of college grade in China with staff and equipment for adequate science teaching was so small as to be negligible, and

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The Future of Phytohormone Societies

The Future of Phytohormone Societies

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2005年全国植物生长物质研讨会

作者： Louise ferguson Department of Pomology University of California at Davis1 Shields AveDavis CA 95616USA

＜正＞There have been five great revolutions in *** are, the use of draft animals, Mendelian genetics, the industrial revolution, agricultural chemicals and molecular techniques. Phytohormones played a large role in the fourth revolution and will play an even larger role in the *** the fourth revolution, when phytohormones were first discovered scientists focused on delineating their function in *** results were only as good as the techniques available and dictated the current production *** example, the effect of gibberellins on cell growth led to Dr. Charles Coggins’s work determining the use of gibberellin to maintain citrus peel

关键词： Phytohormone Gibberellins revolution

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Epidemiology of pelvic and acetabular fractures across 12-mo at a level-1 trauma centre

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World Journal of Orthopedics 2022年第8期13卷 744-752页

作者： rory Cuthbert Samuel Walters David ferguson Edward Karam Jonathan Ward Homa Arshad Paul Culpan Peter Bates Department of Trauma and Orthopaedic Surgery Royal London HospitalBarts HealthLondon E11BBUnited Kingdom

BACKGrOUND Despite motor-vehicle safety advancements and increasingly rigorous workplace safety regulations,trauma/suicide remains the leading cause of death under the age of 45 in the United *** promote centralisation of care and optimisation of major trauma outcomes,in 2012 the National Health Service introduced the Trauma Network *** our knowledge,this is the first study to analyse the epidemiology of pelvic and acetabular trauma over a one-year period at a level-1 trauma centre in the United Kingdom,since nationwide introduction of the Trauma Network *** To characterize the epidemiology of high-energy pelvic and acetabular fractures over a one-year period at a level-1 trauma centre,and explore both resources required to care for these patients and opportunities for future research and injury prevention *** 227 consecutive patients at a level-1 trauma centre with pelvic and acetabular fractures were analysed between December 2017-December *** patients(rs)and fragility fractures were excluded,leaving 175 patients for inclusion in the *** analysis was performed using Fisher’s exact test for categorical *** 72%of pelvic and acetabular fractures occurred in male patients at a median age of 45 years.15%were the result of a suicide attempt.48%of patients required pelvic or acetabular surgery,with 38%undergoing further surgery for additional orthopaedic injuries.43%of patients were admitted to intensive *** median inpatient stay was 13 days,and the 30-day mortality was 5%.Pelvic ring trauma was more commonly associated with abdominal injury(P=0.01)and spine fractures(Pr *** shear pelvic ring fractures were associated with falls(P=0.03)while lateral compression fractures were associated with road traffic accidents(P=0.01).CONCLUSION High energy pelvic and acetabular fractures are associated with concomitant orthopaedic fractures(most commonly spine

关键词： Pelvis Acetabulum Orthopedics Multiple trauma Trauma centers

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Disrupted Maturation of Prefrontal Layer 5 Neuronal Circuits in an Alzheimer’s Mouse Model of Amyloid Deposition

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Neuroscience Bulletin 2023年第6期39卷 881-892页

作者： Chang Chen Jing Wei Xiaokuang Ma Baomei Xia Neha Shakir Jessica K.Zhang Le Zhang Yuehua Cui Deveroux ferguson Shenfeng Qiu Feng Bai Department of Neurology Affiliated Drum Tower HospitalMedical School of Nanjing UniversityNanjing210008China Basic Medical Sciences University of Arizona College of Medicine-PhoenixPhoenixAZ85004USA

Mutations in genes encoding amyloid precursor protein(APP)and presenilins(PSs)cause familial forms of Alzheimer’s disease(AD),a neurodegenerative disorder strongly associated with *** is currently unknown whether and how AD risks affect early brain development,and to what extent subtle synaptic pathology may occur prior to overt hallmark AD *** mutant APP/PS1 over-expression mouse lines are key tools for studying the molecular mechanisms of AD *** these lines,the 5XFAD mice rapidly develop key features of AD pathology and have proven utility in studying amyloid plaque formation and amyloidβ(Aβ)-induced *** reasoned that transgenic mutant APP/PS1 over-expression in 5XFAD mice may lead to neurodevelopmental defects in early cortical neurons,and performed detailed synaptic physiological characterization of layer 5(L5)neurons from the prefrontal cortex(PFC)of 5XFAD and wild-type littermate controls.L5 PFC neurons from 5XFAD mice show early APP/Aβ***-cell patch-clamp recording at an early post-weaning age(P22–30)revealed functional impairments;although 5XFAD PFC-L5 neurons exhibited similar membrane properties,they were intrinsically less *** addition,these neurons received smaller amplitude and frequency of miniature excitatory synaptic *** functional disturbances were further corroborated by decreased dendritic spine density and spine head volumes that indicated impaired synapse *** biotinylation followed by Western blot analysis of PFC-L5 tissue revealed that 5XFAD mice showed reduced synaptic AMPA receptor subunit GluA1 and decreased synaptic NMDA receptor subunit *** with this,patch-clamp recording of the evoked L23>L5 synaptic responses revealed a reduced AMPA/NMDA receptor current ratio,and an increased level of AMPAr-lacking silent *** results suggest that transgenic mutant forms of APP/PS1 overexpression in 5XFAD mice leads to early deve

关键词： Alzheimer’s disease Mouse model Synaptic plasticity Long-term potentiation Cortical circuit Electrophysiology Learning and memory

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洋地黄与心衰时神经激素的异常及其治疗的联系

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国外医学（心血管疾病分册） 1993年第1期20卷 16-18页

作者： ferguson DW 王健

心衰的主要病理生理特征是神经激素的激活,主要是交感神经系统兴奋。经实验研究证实:临床心衰的特征是交感神经对心肌的作用增强,其程度与心肌功能相平行,当给心衰患者应用洋地黄时,除有正性肌力作用外,还有很强的自主神经系统作用。

关键词：洋地黄心力衰竭神经激素

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挥手

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疯狂英语（初中天地） 2006年第1期 30-31页

作者： Sarah ferguson 芥子

上次在法国南部期间、我习惯在一条安静的路上骑自行车。在转角处我会经过一座不大的老房子,院子里有一位胖胖的、脸色红润的妇人,她总是穿着花围裙和绒毛拖鞋。不知为何,她身上有一些东西引起了我的兴趣,她让我有伸出手的冲动。... 详细信息

上次在法国南部期间、我习惯在一条安静的路上骑自行车。在转角处我会经过一座不大的老房子,院子里有一位胖胖的、脸色红润的妇人,她总是穿着花围裙和绒毛拖鞋。不知为何,她身上有一些东西引起了我的兴趣,她让我有伸出手的冲动。当我经过的时候,我向她挥手。她一定认为我只是一个无聊的旅行者,因为她没有向我挥手。

关键词：早上好外科手术

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Driving the slurry TBMs for Shanghai Yangtze river Tunnel

Driving the slurry TBMs for Shanghai Yangtze River Tunnel

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作者： G.ferguson Maunsell Geotechnical Services Ltd. Maunsell Aecom Group

The twin 15.43 diameter slurry TBMs provided for boring the two 7.5 kilometre road tunnels,for the underground section of the river crossing link from Pudong,Shanghai to Chongming Island,were designed to deal with very soft ground conditions including clay,silts and sand under high hydrostatic pressures and relatively low *** paper will concentrate on the TBM's performance in dealing with the following:(1) launching the TBMs from the Launch Shaft;(2) the initial driving with shallow cover;(3) the steering of the TBM and guidance system;(4) the grouting system during the TBM advance;(5) the ring building operation and the ring type;(6) the separation plant for re-cycling the slurry and maintaining its required *** paper will also include a short description about the development of the slurry TBM to its present set up and describe the advantages of the TBM's grouting *** type of rings used on this project is compared to other types on other projects.

关键词： red Driving the slurry TBMs for Shanghai Yangtze river Tunnel

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