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Ultrafast laser state active controlling based on anisotropic quasi-1D material

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Light(Science & Applications) 2024年第4期13卷 717-726页

作者： Zixin Yang Qiang Yu Jian Wu Haiqin Deng Yan Zhang Wenchao Wang Tianhao Xian luyi huang Junrong Zhang Shuai Yuan Jinyong Leng Li Zhan Zongfu Jiang Junyong Wang Kai Zhang Pu Zhou College of Advanced Interdisciplinary Studies National University of Defense TechnologyChangsha 410073China. Nanhu Laser Laboratory National University of Defense TechnologyChangsha 410073China. i-Lab&Key Laboratory of Nanodevices and Applications&Key Laboratory of Nanophotonic Materials and Devices Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China. School of Applied and Engineering Physics Cornell UniversityIthacaNY 14853USA. State Key Laboratory of Advanced Optical Communication Systems and Networks School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China. Shanghai Key Lab of Modern Optical System University of Shanghai for Science and TechnologyShanghai 200093China

Laser state active controlling is challenging under the influence of inherent loss and other nonlinear effects in ultrafast *** an extension of degree of freedom in optical devices based on low-dimensional materials may be a way ***,the anisotropic quasi-one-dimensional layered material Ta2PdS6 was utilized as a saturable absorber to modulate the nonlinear parameters effectively in an ultrafast system by polarization-dependent *** polarization-sensitive nonlinear optical response facilitates the Ta2PdS6-based mode-lock laser to sustain two types of laser states,i.e.,conventional soliton and noise-like *** laser state was switchable in the single fiber laser with a mechanism revealed by numerical *** coding was further demonstrated in this platform by employing the laser as a codable light *** work proposed an approach for ultrafast laser state active controlling with low-dimensional material,which offers a new avenue for constructing tunable on-fiber devices.

关键词： polarization fiber controlling

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银杏内酯B对肥胖小鼠的改善作用研究

食品工业科技 2024年第6期45卷 337-342页

作者：尹忞强罗来庆汤海莲陈金女李琴黄露怡焦宇知江苏食品药品职业技术学院江苏淮安223001 江苏联合职业技术学院苏州旅游与财经分院江苏苏州215000

为探究银杏内酯B(ginkgolide B,GB)对肥胖小鼠的干预作用,首先采用高脂膳食诱导构建C57BL/6J小鼠肥胖模型,随后将肥胖小鼠按体重随机分为4组,模型组(PG)、GB低剂量组(GBL)、GB中剂量组(GBM)和GB高剂量组(GBH),进行为期8周的干预实验,测... 详细信息

为探究银杏内酯B(ginkgolide B,GB)对肥胖小鼠的干预作用,首先采用高脂膳食诱导构建C57BL/6J小鼠肥胖模型,随后将肥胖小鼠按体重随机分为4组,模型组(PG)、GB低剂量组(GBL)、GB中剂量组(GBM)和GB高剂量组(GBH),进行为期8周的干预实验,测定各组小鼠肥胖相关指标,如体重变化、脏器脂肪系数、血脂指标等。GB干预后,GBM和GBH组小鼠的体重增长明显小于PG组(P<0.05),同时,GBH组的小鼠脏器脂肪系数均显著降低(P<0.05)。另外,GBM和GBH组小鼠的血脂指标总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HLD-C)均得到显著(P<0.05)改善,尤其是GBH组小鼠;最后,组织病理学结果显示,GBM和GBH组小鼠肝脏脂肪沉积明显减轻。进一步实时荧光定量聚合酶链式反应(Quantitative Real-time Polymerase Chain Reaction,qRT-PCR)结果显示,和PG组相比,GBM和GBH组小鼠肝脏中过氧化物酶体增殖物激活受体γ(peroxisome proliferator-activated receptorγ,PPARγ)的mRNA表达水平显著降低(P<0.05),而解偶联蛋白2(Uncoupling protein 2,UCP-2)的mRNA水平显著增加(P<0.05)。本研究发现中高剂量的GB可以有效改善小鼠的肥胖,并且这种改善作用可能和PPARγ-UCP-2信号途径相关。

关键词：银杏内酯B 肥胖小鼠银杏改善作用

O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N^(6)-methyladenosine-dependent manner

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1208-1223页

作者： Yang Yang Yu Yan Jiaxin Yin Ni Tang Kai Wang luyi huang Jie Hu Zhongqi Feng Qingzhu Gao Ailong huang Institute for Viral Hepatitis Key Laboratory of Molecular Biology for Infectious Diseases(Ministry of Education)Department of Infectious DiseasesThe Second Affiliated HospitalChongqing Medical UniversityChongqingChina

Hepatitis B virus(HBV)infection is a major risk factor for hepatocellular carcinoma(HCC),but its pathogenic mechanism remains to be *** RNA N^(6)-methyladenosine(m^(6)A)reader,YTH(YT521-B homology)domain 2(YTHDF2),plays a critical role in the HCC ***,the function and regulatory mechanisms of YTHDF2 in HBV-related HCC remain largely ***,we discovered that YTHDF2 O-GlcNAcylation was markedly increased upon HBV infection.O-GlcNAc transferase(OGT)-mediated O-GlcNAcylation of YTHDF2 on serine 263 enhanced its protein stability and oncogenic activity by inhibiting its ***,YTHDF2 stabilized minichromosome maintenance protein 2(MCM2)and MCM5 transcripts in an m^(6)A-dependent manner,thus promoting cell cycle progression and HBV-related HCC ***,targeting YTHDF2 O-GlcNAcylation by the OGT inhibitor OSMI-1 significantly suppressed HCC *** together,our findings reveal a new regulatory mechanism for YTHDF2 and highlight an essential role of YTHDF2 O-GlcNAcylation in RNA m^(6)A methylation and HCC *** description of the molecular pathway has the potential to yield therapeutic targets for suppression of HCC progression due to HBV infection.

关键词： hepatocellular markedly DF2

Wafer-scale patterned growth of type-II Dirac semimetal platinum ditelluride for sensitive room-temperature terahertz photodetection

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InfoMat 2023年第5期5卷 17-27页

作者： Zhuo Dong Wenzhi Yu Libo Zhang Liu Yang luyi huang Yan Zhang Zeqian Ren Haoran Mu Cheng Chen Junrong Zhang Jie Li Lin Wang Kai Zhang CAS Key Laboratory of Nanophotonic Materials and Devices&Key Laboratory of Nanodevices and Applications i-LabSuzhou Institute of Nano-Tech and Nano-Bionics(SINANO)Chinese Academy of SciencesSuzhouJiangsuthe People's Republic of China School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefeiAnhuithe People's Republic of China Songshan Lake Materials Laboratory DongguanGuangdongthe People's Republic of China State Key Laboratory for Infrared Physics Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghaithe People's Republic of China

As the lastly unexplored electromagnetic wave,terahertz(THz)radiation has been exploited in a plenty of contexts such as fundamental research,military and civil *** recently,representative two-dimensional(2D)topological semimetal,platinum ditelluride(PtTe_(2))has attracted considerable research interest in THz detection due to its unique physical ***,to achieve practical applications,the low-cost,large-scale,controllable synthesis and efficient patterning of 2D materials are key requirements,which remain a challenge for PtTe_(2)and its photodetectors(PDs).Herein,a facile approach is developed to obtain waferscale(2-inches)patterned PtTe_(2)arrays using one-step tellurium-vapor transformation method and micro-Nano ***_(2)PD arrays are fabricated with the as-grown PtTe_(2)arrays evenly distributed on a 2-inch wafer,exhibiting high conductivity(~2.7×105 S m^(-1))and good electrical *** by the Dirac fermions,PtTe_(2)PDs achieve a broadband(0.02-0.3 THz)response with a fast response speed(~4.7μs),a high sensitivity(~47 pW Hz^(-1/2))and high-resolution transmission THz-imaging capability,which displays the potential of large-area THz array *** results are one step towards the practical applications of integrated PD arrays based on 2D materials.

关键词： patterned growth photodetection platinum ditelluride terahertz wafer-scale

Low-loss and polarization insensitive 32×4 optical switch for ROADM applications

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Light(Science & Applications) 2024年第5期13卷 875-884页

作者： Xiaotian Zhu Xiang Wang Yanlu huang Liyan Wu Chunfei Zhao Mingzhu Xiao luyi Wang Roy Davidson Yanni Ou Brent E.Little Sai T.Chu Department of Physics City University of Hong KongTat Chee AvenueHong KongChina. QXP Technologies Inc. NO.15th Shanglinyuan 1st RoadXi’anShaanxi 710119China. State Key Laboratory of Information of Photonics and Optical Communications School of Electronic EngineeringBeijing University of Posts and TelecommunicationsBeijing 100876China

Integrated switches play a crucial role in the development of reconfigurable optical add-drop multiplexers(ROADMs)that have greater flexibility and compactness,ultimately leading to robust single-chip *** decades of research on switches with various structures and platforms,achieving a balance between dense integration,low insertion loss(IL),and polarization-dependent loss(PDL)remains a significant *** this paper,we propose and demonstrate a 32×4 optical switch using high-index doped silica glass(HDSG)for ROADM *** switch is designed to route any of the 32 inputs to the express ports or drop any channels from 32 inputs to the target 4 drop ports or add any of the 4 ports to any of the 32 express *** switch comprises 188 MachZehnder Interferometer(MZI)type switch elements,88 optical vias for the 44 optical bridges,and 618 waveguidewaveguide crossings with three-dimensional(3D)*** 1550 nm,the fiber-to-fiber loss for each express channel is below 2 dB,and across the C and L bands,below 3 *** each input channel to all 4 drop/add channels at 1550 nm,the loss is less than 3.5 dB and less than 5 dB across the C and L *** PDLs for all express and input channels to the 4 drop/add channels are below 0.3 dB over the C band,and the crosstalk is under−50 dB for both the C and L bands.

关键词： polarization ROADM optical

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一种光控电压泵的特性与仿真

复旦学报（自然科学版） 2019年第1期58卷 64-71页

作者：严利民黄璐益上海大学微电子研究与开发中心上海200444

光金属氧化物半导体(MOS)固态继电器出厂后,存在无法调整带负载能力的缺点.本文研究了一种光控电压泵,用户可以根据需求自己选配外接的金属氧化物半导体场效应晶体管(MOSFET),从而使光控电压泵应用范围更加广泛,还有利于性价比的优化.... 详细信息

光金属氧化物半导体(MOS)固态继电器出厂后,存在无法调整带负载能力的缺点.本文研究了一种光控电压泵,用户可以根据需求自己选配外接的金属氧化物半导体场效应晶体管(MOSFET),从而使光控电压泵应用范围更加广泛,还有利于性价比的优化.为了研究这款光控电压泵的特性,本文分别在稳态以及瞬态两种工况下,对它进行性能指标的测试.并且建立了相应的仿真模型,再应用OrCAD软件进行仿真,其仿真的结果与测试数据对比,显示二者之间的稳态误差约为1.0%,瞬态误差约为0.69%.

关键词：光控电压泵建模 OrCAD

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亚/超临界乙醇液化玉米秸秆反应路径与机理

农业工程学报 2010年第6期26卷 277-282页

作者：刘华敏解新安丁年平刘焕彬黄璐怡华南农业大学食品学院广州510641 华南农业大学生物质能研究所广州510641 华南理工大学制浆造纸工程国家重点实验室广州510641

为了建立玉米秸秆在亚/超临界乙醇中进行液化各集总组分之间的主要反应路径图,考查反应过程中乙醇对产物的影响机理。该文利用集总的方法,根据产物和原料的性质将产物与原料分为气体、易挥发物、轻油、重油、固体物5个集总,考查了液化过... 详细信息

为了建立玉米秸秆在亚/超临界乙醇中进行液化各集总组分之间的主要反应路径图,考查反应过程中乙醇对产物的影响机理。该文利用集总的方法,根据产物和原料的性质将产物与原料分为气体、易挥发物、轻油、重油、固体物5个集总,考查了液化过程(升温过程和反应过程)和乙醇量对各集总产物的分布规律的影响,建立了5集总组分之间的主要液化反应路径图。结果表明,玉米秸秆在反应温度到达180℃之前主要是水溶性有机物参加反应,主要生成了挥发物、气体与少量的重油;当反应温度达到180℃之后玉米秸秆3种主要成分(纤维素、半纤维素、木质素)开始液化,主要产物是挥发物、轻油、重油和气体;液化过程中挥发物与重油之间存在着可逆反应,轻油在液化过程中发生二次反应主要生成气体。乙醇在液化过程中除了起到了传热作用和充当反应溶剂外还为反应过程提供自由基,对产物起到了重整作用。

关键词：乙醇液化集总参数网络机理玉米秸秆

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罗陆一望前额辨治肺系疾病经验介绍

新中医 2024年第14期56卷 217-221页

作者：黄慧春毕尚青罗陆一(指导) 广州中医药大学第七临床医学院广东深圳518133 深圳市宝安中医院(集团) 广东深圳518133 深圳市中医院广东深圳518033

介绍罗陆一教授望前额辨治肺系疾病的临床经验。罗陆一教授认为,前额可反映肺脏气血充盈与否,甚至可反映全身气血阴阳之变化。正常前额表现为饱满红润。望前额可大体分为望前额之形态、望前额之色,临证将前额形态与色二者相结合进行综... 详细信息

介绍罗陆一教授望前额辨治肺系疾病的临床经验。罗陆一教授认为,前额可反映肺脏气血充盈与否,甚至可反映全身气血阴阳之变化。正常前额表现为饱满红润。望前额可大体分为望前额之形态、望前额之色,临证将前额形态与色二者相结合进行综合判断,若连续多次比较,还可预知疾病的发展趋势。

关键词：肺系疾病望诊望前额罗陆一

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高强度风电灌浆料的配制及其性能研究

新型建筑材料 2024年第4期51卷 68-71页

作者：黄有强陈露一蔡昱周毅郑丽李信桥梁智能与绿色建造全国重点实验室湖北武汉430034 中铁桥研科技有限公司湖北武汉430034 中铁大桥科学研究院有限公司湖北武汉430034

分别设计了抗压强度达120、130、140 MPa级的高强度风电灌浆料配比A、B、C,并对其性能进行了研究。结果表明,配比A、B、C流动度、抗压强度、竖向膨胀率等关键指标均能满足设计要求。为保证灌浆料良好的施工性能和微膨胀性能,粉体减水剂... 详细信息

分别设计了抗压强度达120、130、140 MPa级的高强度风电灌浆料配比A、B、C,并对其性能进行了研究。结果表明,配比A、B、C流动度、抗压强度、竖向膨胀率等关键指标均能满足设计要求。为保证灌浆料良好的施工性能和微膨胀性能,粉体减水剂掺量不宜低于0.5%,同时塑性膨胀剂掺量不宜低于0.024%。对配比B不同温度下工作性能和力学性能的研究显示,随着环境温度的升高,风电灌浆料初始流动度降低,流动度经时损失变大。风电灌浆料在10℃环境中养护,对各龄期抗压强度均有影响,在30、40、50℃环境中养护,各龄期抗压强度均有一定幅度提高,低温或高温对1 d龄期影响最大。为保证灌浆料的施工性能,适宜施工环境温度为10~40℃,否则需采取降温或保温措施。

关键词：风电灌浆料流动度力学性能环境温度