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The Crop Journal 2024年第3期12卷 880-887页

作者： Xiaoling Wang Jiawei Cao Runhong Sun Wei liu Lin Qi Peng Song Shenjiao Yang College of Agronomy Henan University of Science and TechnologyLuoyang 471003HenanChina Institute of Plant Protection Research Henan Academy of Agricultural SciencesZhengzhou 450099HenanChina Farmland Irrigation Research Institute Chinese Academy of Agricultural SciencesXinxiang 453000HenanChina

A two-year field experiment conducted under dryland conditions in semi-humid and drought-prone regions of China aimed to assess the effect of ammonia-oxidizing bacterial on maize water use efficiency and yield.A heterotrophic ammonia-oxidizing bacteria(HAOB)strain S2_8_1 was *** treatments were applied:(1)no irrigation+HAOB strain(DI),(2)no irrigation+blank culture medium(DM),(3)no irrigation control(DCK),(4)irrigation+HAOB(WI),(5)irrigation+blank culture medium(WM),and(6)irrigation control(WCK).Results revealed that HAOB treatment increased maize growth,yield,and water use efficiency over controls,regardless of whether the year was wet or *** improvement was attributed to the accelerated nitrification in the rhizosphere soil due to HAOB inoculation,which subsequently led to increased levels of leaf ***,these findings suggest that HAOB inoculation holds promise as a strategy to boost water use efficiency and maize productivity in dryland agriculture.

关键词： Heterotrophic ammonia-oxidizing bacteria Rhizosphere soil nitrification Cytokinin Maize Dryland agriculture

Metal–organic compounds as promising anode materials for potassium ion batteries: A mini review

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Energy Reviews 2024年第1期3卷 90-108页

作者： jinquan Wen Qian liu Ling Bai Zhen-Dong Huang Yanwen Ma State Key Laboratory for Organic Electronics and Information Displays&Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)Nanjing University of Posts and Telecommunications9 Wenyuan RoadNanjing 210023PR China

Potassium-ion batteries(PIBs)represent one of the most promising alternatives to lithium-ion batteries(LIBs),owing to their exceptional attributes such as high voltages,potent power capabilities,and ***,challenges arise from the sluggish kinetics and significant volume expansion observed during the insertion/extraction of large-radii potassium ions,leading to subpar rate performance and considerable capacity degradation in potassium-ion ***,it becomes imperative to explore advanced anode materials exhibiting high electrochemical activity and robust structural *** this regard,the present review focuses on recent progress in metal-organic compounds(MOCs)as anode materials for potassium-ion batteries,systematically discussing their outstanding merits from the perspective of metal ***,the principal mechanism of K ion storage within relevant MOCs is ***,a comprehensive summary of existing drawbacks that hinder the broader application of MOCs-based materials is provided,along with proposed guidelines and strategies for addressing the inferior performance *** review serves to illuminate the development of MOCs-based anode materials for potassium-ion batteries and offers a valuable reference for future research endeavors.

关键词： Potassium ion batteries Anode materials Metal organic compounds Metals organic frameworks

A Two-Layer Active Power Optimization and Coordinated Control for Regional Power Grid Partitioning to Promote Distributed Renewable Energy Consumption

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Energy Engineering 2024年第9期121卷 2479-2503页

作者： Wentao Li Jiantao liu Yudun Li GuoxinMing Kaifeng Zhang Kun Yuan Key Laboratory of Measurement and Control of CSE Southeast UniversityNanjing210096China China Electric Power Research Institute Nanjing210003China State Grid Shandong Electric Power Research Institute Jinan250003China

With the large-scale development and utilization of renewable energy,industrial flexible loads,as a kind of loadside resource with strong regulation ability,provide new opportunities for the research on renewable energy consumption problem in power *** paper proposes a two-layer active power optimization model based on industrial flexible loads for power grid partitioning,aiming at improving the line over-limit problem caused by renewable energy consumption in power grids with high proportion of renewable energy,and achieving the safe,stable and economical operation of power ***,according to the evaluation index of renewable energy consumption characteristics of line active power,the power grid is divided into several partitions,and the interzone tie lines are taken as the optimization ***,on the basis of partitioning,a two-layer active power optimization model considering the power constraints of industrial flexible loads is *** upper-layer model optimizes the planned power of the inter-zone tie lines under the constraint of the minimum peak-valley difference within a day;the lower-layer model optimizes the regional source-load dispatching plan of each resource in each partition under the constraint of theminimumoperation cost of the partition,so as to reduce the line overlimit phenomenon caused by renewable energy consumption and save the electricity cost of industrial flexible ***,through simulation experiments,it is verified that the proposed model can effectively mobilize industrial flexible loads to participate in power grid operation and improve the economic stability of power grid.

关键词： Renewable energy consumption active power optimization power grid partitioning industrial flexible loads line over-limit

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战斗机驾驶舱环境热舒适性仿真与优化

航空学报 2024年第7期45卷 122-133页

作者：刘钟琦胡旭阳罗海宁王晓明董素君北京航空航天大学航空科学与工程学院北京100191 航空工业成都飞机设计研究所成都610091

战斗机驾驶舱环境热舒适性是保障飞行员人机工效,确保战斗机发挥最佳作战性能的重要因素。但是,常用预期平均投票数-预期不满意百分数(PMV-PPD)人体热舒适性评价指标无法适用于驾驶舱内极度不均匀流场和温度场环境,驾驶舱环境热舒适性... 详细信息

战斗机驾驶舱环境热舒适性是保障飞行员人机工效,确保战斗机发挥最佳作战性能的重要因素。但是,常用预期平均投票数-预期不满意百分数(PMV-PPD)人体热舒适性评价指标无法适用于驾驶舱内极度不均匀流场和温度场环境,驾驶舱环境热舒适性缺乏有效优化设计手段。首先利用STAR-CCM+、TAITherm 2个软件,实现了驾驶舱内气流组织与Fiala人体生理模型和Berkeley热舒适评价指标的联合仿真功能;进一步以人体热舒适性和温度不均匀性系数为优化指标,采用遗传算法(GA)对驾驶舱多个送风口流量分配进行一定优化设计。与传统非耦合求解方法相比,联合仿真方法可有效提升驾驶舱内飞行员皮肤温度与热舒适性计算精度。与原始设计方案相比,优化后人体周围环境温度不均匀系数改善16%,整体热舒适性提升了0.285,占该档量化表阶梯的14%。同时,优化方案绝大部分局部热感受、热舒适性都有不同程度的改善。其中,头部和颈部改善最大,颈部热感受与热舒适性分别提高了0.55、0.781,分别占该档量化表阶梯的55%、39%。

关键词：驾驶舱热舒适性气流组织战斗机送风系统优化

Transient induction of actin cytoskeletal remodeling associated with dedifferentiation,proliferation,and redifferentiation stimulates cardiac regeneration

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2537-2553页

作者： Wenbin Fu Qiao Liao Yu Shi Wujian liu Hongmei Ren Chunmei Xu Chunyu Zeng Department of Cardiology Daping Hospitalthe Third Military Medical University(Army Medical University)Chongqing 400042China Key Laboratory of Geriatric Cardiovascular and Cerebrovascular Disease Research Ministry of Education of ChinaChongqing 400042China Chongqing Key Laboratory for Hypertension Research Chongqing Cardiovascular Clinical Research CenterChongqing Institute of CardiologyChongqing 400042China State Key Laboratory of Trauma Burns and Combined InjuryDaping Hospitalthe Third Military Medical UniversityChongqing 400042China Cardiovascular Research Center Chongqing CollegeUniversity of Chinese Academy of SciencesChongqing 400042China State Key Laboratory of Trauma and Chemical Poisoning Chongqing 400042China

The formation of new and functional cardiomyocytes requires a 3-step process:dedifferentiation,proliferation,and redifferentiation,but the critical genes required for efficient dedifferentiation,proliferation,and redifferentiation remain *** our study,a circular trajectory using single-nucleus RNA sequencing of the pericentriolar material 1 positive(PCM1^(+))cardiomyocyte nuclei from hearts 1 and 3 days after surgery-induced myocardial infarction(MI)on postnatal Day 1 was reconstructed and demonstrated that actin remodeling contributed to the dedifferentiation,proliferation,and redifferentiation of cardiomyocytes after *** identified four top actin-remodeling regulators,namely Tmsb4x,Tmsb10,Dmd,and Ctnna3,which we collectively referred to as *** expressed changes of 2D2P,using a polycistronic non-integrating lentivirus driven by Tnnt2(cardiac-specific troponin T)promoters(Tnnt2-2D2P-NIL),efficiently induced transiently proliferative activation and actin remodeling in postnatal Day 7 cardiomyocytes and adult ***,the intramyocardial delivery of Tnnt2-2D2P-NIL resulted in a sustained improvement in cardiac function without ventricular dilatation,thickened septum,or fatal arrhythmia for at least 4 *** conclusion,this study highlights the importance of actin remodeling in cardiac regeneration and provides a foundation for new gene-cocktail-therapy approaches to improve cardiac repair and treat heart failure using a novel transient and cardiomyocyte-specific viral construct.

关键词： Single cell analysis Actin remodeling Tmsb4x Tmsb10 Dmd Ctnna3 Myocardial infarction Cardiomyocytes proliferation Cardiac regeneration Genetic therapy

Text Difficulty Study:Do Machines Behave the Same as Humans Regarding Text Difficulty?

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Machine Intelligence Research 2024年第2期21卷 283-293页

作者： Bowen Chen Xiao Ding Yi Zhao Bo Fu Tingmao Lin Bing Qin Ting liu Research Center for Social Computing and Information Retrieval Harbin Institute of TechnologyHarbin 150001China Fundamental Technology Center China Construction Bank Financial Technology Co.Ltd.Beijing 100033China

With the emergence of pre-trained models,current neural networks are able to give task performance that is comparable to ***,we know little about the fundamental working mechanism of pre-trained models in which we do not know how they approach such performance and how the task is solved by the *** example,given a task,human learns from easy to hard,whereas the model learns ***,difficulty-insensitive learning leads to great success in natural language processing(NLP),but little attention has been paid to the effect of text difficulty in *** propose a human learning matching index(HLM Index)to investigate the effect of text *** results show:1)LSTM gives more human-like learning behavior than ***,UID-SuperLinear gives the best evaluation of text difficulty among four text difficulty *** nine tasks,some tasks’performance is related to text difficulty,whereas others are not.2)Model trained on easy data performs best in both easy and medium test data,whereas trained on hard data only performs well on hard test data.3)Train the model from easy to hard,leading to quicker convergence.

关键词： Cognition inspired natural language processing psycholinguistics explainability text difficulty curriculum learning

Tanshinone IIA ameliorates energy metabolism dysfunction of pulmonary fibrosis using 13C metabolic flux analysis

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Journal of Pharmaceutical Analysis 2024年第2期14卷 244-258页

作者： Baixi Shan Haoyan Zhou Congying Guo Xiaolu liu Mingyu Wu Rao Zhai Jun Chen State Key Laboratory of Natural Medicines China Pharmaceutical UniversityNanjing210009China Department of Pharmacognosy School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing210009China

Evidence indicates that metabolic reprogramming characterized by the changes in cellular metabolic patterns contributes to the pathogenesis of pulmonary fibrosis (PF). It is considered as a promising therapeutic target anti-PF. The well-documented against PF properties of Tanshinone IIA (Tan IIA) have been primarily attributed to its antioxidant and anti-inflammatory potency. Emerging evidence suggests that Tan IIA may target energy metabolism pathways, including glycolysis and tricarboxylic acid (TCA) cycle. However, the detailed and advanced mechanisms underlying the anti-PF activities remain obscure. In this study, we applied [U-13C]-glucose metabolic flux analysis (MFA) to examine metabolism flux disruption and modulation nodes of Tan IIA in PF. We identified that Tan IIA inhibited the glycolysis and TCA flux, thereby suppressing the production of transforming growth factor-β1 (TGF-β1)-dependent extracellular matrix and the differentiation and proliferation of myofibroblasts in vitro. We further revealed that Tan IIA inhibited the expression of key metabolic enzyme hexokinase 2 (HK2) by inhibiting phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR)/hypoxia-inducible factor 1α (HIF-1α) pathway activities, which decreased the accumulation of abnormal metabolites. Notably, we demonstrated that Tan IIA inhibited ATP citrate lyase (ACLY) activity, which reduced the collagen synthesis pathway caused by cytosol citrate consumption. Further, these results were validated in a mouse model of bleomycin-induced PF. This study was novel in exploring the mechanism of the occurrence and development of Tan IIA in treating PF using 13C-MFA technology. It provided a novel understanding of the mechanism of Tan IIA against PF from the perspective of metabolic reprogramming.

关键词： Pulmonary fibrosis Tanshinone IIA 13C-metabolic flux analysis Metabolic reprogramming

Impacts of Future Changes in Heavy Precipitation and Extreme Drought on the Economy over South China and Indochina

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Advances in Atmospheric Sciences 2024年第6期41卷 1184-1200,I0022-I0034页

作者： Bin TANG Wenting HU Anmin DUAN Yimin liu Wen BAO Yue XIN Xianyi YANG State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 101408China State Key Laboratory of Marine Environmental Science College of Ocean and Earth SciencesXiamen UniversityXiamen 361005China Chinese Academy of Sciences the CAS Institutes of Science and DevelopmentBeijing 101408China School of Public Policy and Management University of Chinese Academy of SciencesBeijing 101408China

Heavy precipitation and extreme drought have caused severe economic losses over South China and Indochina(INCSC)in recent *** the areas with large gross domestic product(GDP)in the INCSC region are distributed along the coastline and greatly affected by global warming,understanding the possible economic impacts induced by future changes in the maximum consecutive 5-day precipitation(RX5day)and the maximum consecutive dry days(CDD)is critical for adaptation planning in this *** on the latest data released by phase 6 of the Coupled Model Intercomparison Project(CMIP6),future projections of precipitation extremes with bias correction and their impacts on GDP over the INCSC region under the fossil-fueled development Shared Socioeconomic Pathway(SSP5-8.5)are *** indicate that RX5day will intensify robustly throughout the INCSC region,while CDD will lengthen in most regions under global *** changes in climate consistently dominate the effect on GDP over the INCSC region,rather than the change of *** only considering the effect of climate change on GDP,the changes in precipitation extremes bring a larger impact on the economy in the future to the provinces of Hunan,Jiangxi,Fujian,Guangdong,and Hainan in South China,as well as the Malay Peninsula and southern Cambodia in ***,timely regional adaptation strategies are urgent for these ***,from the sub-regional average viewpoint,over two thirds of CMIP6 models agree that maintaining a lower global warming level will reduce the economic impacts from heavy precipitation over the INCSC region.

关键词： CMIP6 heavy precipitation extreme drought South China Indochina economic impact

基于形貌全覆盖的岩石结构面抗剪强度尺寸效应试验研究

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岩石力学与工程学报 2024年第2期43卷 287-297页

作者：罗战友黄斌杜时贵黄曼吕原君刘广建绍兴文理学院土木工程学院浙江绍兴312000 宁波大学岩石力学研究所浙江宁波315211

岩石结构面抗剪强度具有尺寸效应已成为学术与工程界共识,但现有理论和数值研究表明岩石结构面抗剪强度可能具有正尺寸效应、负尺寸效应或无尺寸效应的变化规律,由于结构面抗剪强度尺寸效应试验的难度大、费用高、周期长,造成系列尺寸... 详细信息

岩石结构面抗剪强度具有尺寸效应已成为学术与工程界共识,但现有理论和数值研究表明岩石结构面抗剪强度可能具有正尺寸效应、负尺寸效应或无尺寸效应的变化规律,由于结构面抗剪强度尺寸效应试验的难度大、费用高、周期长,造成系列尺寸结构面直剪试验较少,特别是对于起伏形貌全覆盖的系列尺寸(100~600 mm)结构面直剪试验研究还未见报道。基于Barton典型形貌曲线,采用多尺寸结构面一体化模具制作16组系列多尺寸结构面试样,通过自主研发的岩体结构面抗剪强度尺寸效应试验系统开展起伏形貌全覆盖的系列多尺寸结构面直剪试验,并采用三维全场应变测量系统(DIC)开展试验全过程非接触动态变形测量。研究结果表明:(1)形貌全覆盖系列尺寸结构面峰值抗剪强度上渐近线呈现负尺寸效应规律,下渐近线呈现正尺寸效应规律,尺寸效应呈现的具体规律与取样位置及起伏形貌特征相关。(2)不同尺寸试样同一形貌特征结构面会产生剪断、爬坡、耦合等不同剪切破坏模式;相同尺寸试样不同形貌特征结构面的剪切破坏模式也有差异,且表面形貌起伏程度越大其应变增长越快。(3)尺寸越大,具有较大起伏形貌特征的结构面剪应力与剪位移曲线峰值特征越明显;尺寸越小,具有较大起伏形貌特征的结构面峰值抗剪强度离散性越大。(4)基于等权重系数法开展了大尺寸结构面峰值抗剪强度评价,Grasselli公式计算峰值抗剪强度加权评价值与实测值相比误差较大。

关键词：岩石力学岩石结构面抗剪强度尺寸效应直剪试验起伏形貌

Combined blasting for protection of gob-side roadway with thick and hard roof

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第8期16卷 3165-3180页

作者： Qiang Fu Jun Yang Yubing Gao Changjiang Li Hongxu Song Yuxuan liu Xing Wu State Key Laboratory for Tunnel Engineering China University of Mining and Technology(Beijing)Beijing100083China School of Mechanics and Civil Engineering China University of Mining and Technology(Beijing)Beijing100083China

The deformation control of surrounding rock in gobside roadway with thick and hard roof poses a significant challenge to the safety and efficiency of coal *** address this issue,a novel approach combining directional and non-directional blasting techniques,known as combined blasting,was *** study focuses on the experimental investigation of the proposed method in the 122108 working face in Caojiatan Coal Mine as the engineering *** initial phase of the study involves physical model experiments to reveal the underlying mechanisms of combined blasting for protecting gob-side roadway with thick and hard *** results demonstrate that this approach effectively accelerates the collapse of thick and hard roofs,enhances the fragmentation and expansion coefficient of gangue,facilitates the filling of the goaf with gangue,and provides support to the overlying strata,thus reducing the subsidence of the overlying strata above the ***,the method involves cutting the main roof into shorter beams to decrease the stress and disrupt stress transmission *** numerical simulations were conducted to corroborate the findings of the physical model experiments,thus validating the accuracy of the experimental ***,field engineering experiments were performed,affirming the efficacy of the combined blasting method in mitigating the deformation of surrounding rock and achieving the desired protection of the gob-side roadway.

关键词： Thick and hard roof Surrounding rock control Combined blasting Fragmentation and expansion support stress relief