检索结果-南通市图书馆

Discrimination of intra/extracellular sidedness segments of transmembrane proteins

在线全文

学校读者我要写书评

暂无评论

生物物理学报 2009年第S1期25卷 193-194页

作者： Wei Chen, Liao-fu luo School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China

Topology of the transmembrane protein is closely related to its functions. So, it is desiderated to depict the topology of transmembrane proteins. In this work, an effective approach

关键词： transmembrane protein topology increment of diversity quadratic discriminant analysis

Method for identifying effective carbonate source rocks:a case study from Middle-Upper Ordovician in Tarim Basin,China

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2020年第6期17卷 1491-1511页

作者： Jun-Qing Chen Xiong-Qi Pang Song Wu Zhuo-Heng Chen Mei-Ling Hu luo-fu Liu Kui-You Ma Bo Pang Zhi-Peng Huo State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing 102249China Beijing Key Laboratory of Optical Detection Technology for Oil and Gas China University of PetroleumBeijing 102249China College of Geoscience China University of PetroleumBeijing 102249China Geological Survey of Canada CalgaryAB T2L 2A7Canada Research Institute of Petroleum Exploration and Development PetroChina Huabei Oilfi eld CompanyRenqiu 062550HebeiChina China University of Geosciences Beijing 100083China

Hydrocarbon expulsion occurs only when pore fluid pressure due to hydrocarbon generation in source rock exceeds the force against migration in the adjacent carrier *** the Middle-Upper Ordovician carbonate source rock of Tarim Basin in China as an example,this paper proposes a method that identifies effective carbonate source rock based on the principles of mass *** from the Well YW2 indicate that the Middle Ordovician Yijianfang Formation contains effective carbonate source rocks with low present-day *** and geochemical analysis suggests that the hydrocarbons in the carbonate interval are likely self-generated and *** steranes from GC-MS analysis of oil extracts in this interval display similar features to those of the crude oil samples in Tabei area,indicating that the crude oil probably was migrated from the effective source *** applying to other wells in the basin,the identified effective carbonate source rocks and non-source rock carbonates can be effectively identified and consistent with the actual exploration results,validating the *** the contribution from the identified effective source rocks with low present-day TOC(TOC_(pd))is considered,the long-standing puzzle between the proved 3 P oil reserves and estimated resources in the basin can be reasonably explained.

关键词： Effective carbonate source rock Mass balance approach Low present-day TOC Ordovician Tarim Basin

Circadian disturbance induces erectile dysfunction by impairing endothelial function

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2024年第2期26卷 205-211页

作者： Tao Li Yi-Ting Jiang Xin-Zhu Qi Peng Chen Jun-Hao Zhang fu luo Jun Qiao Jiang Gu Guang-Shi Du Qiang Wang Department of Urology Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China Department of Urology Guizhou Provincial People's HospitalGuiyang 550002China Department of Otorhinolaryngology Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China Guizhou Institute for Food and Drug Control Guiyang 550004China Department of Reproductive Center Guizhou Provincial People's HospitalGuiyang 550002China Translational Medicine Research Center of Guizhou Medical University Guiyang 550025China

In order to explore the impact of circadian disturbance on erectile function,we randomly divided 24 adult male rats into groups of control(light on at 8:00 *** off at 8:00 p.m.),dark/dark(DD;constant dark),light/light(LL;constant light),and shift dark/light(DL;light off at 8:00 *** on at 8:0o p.m.).Four weeks later,erectile function was measured and corpora cavernosa were harvested for *** maximum intracavernous pressure(mlcP)and mCP/mean arterial pressure(MAP)ratio in the DD,LL,and DL groups were significantly lower than that in the control *** LL and DL groups showed significantly attenuated endothelial nitric oxide synthase(eNOS),while DD,LL,and DL showed reduced neuronal nitric oxide synthase(nNOS)at both mRNA and protein *** production of nitric oxide(NO)and cyclic guanosinemonophosphate(cGMP)was inhibited by altered light/dark cycles to varying *** disturbance impaired endothelial function and contributed to erectile *** the core circadian elements,mRNA expression of circadian locomotor output cycles kaput(Clock)and brain/muscle aryl-hydrocarbon receptor nuclear translocator-like protein 1(Bmal1)was elevated in the DL group,but their protein expression was not significantly ***,LL,and DL increased period 1(Per1)and Per3 levels,while LL and DL increased PER1 *** significant difference was found for Per2levels,and PER2 and PER3 concentrations were not significantly ***,LL and DL significantly increased cryptochrome-1(CRY1)and CRY2 at both mRNA and protein *** altered light/dark rat model showed that circadian disturbance contributed to erectile dysfunction probably by impairing endothelial ***,the core circadian elements were detected in the corpora cavernosa,but these were ***,which circadian element regulates erectile function and how it works need further analysis.

关键词： circadian disturbance endothelial function erectile function light/dark cycle NO/cGMP

3, 4-seco-Labdane diterpenoids from the leaves of Callicarpa nudiflora with anti-inflammatory effects

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2019年第9期17卷 707-712页

作者： WANG Hong-Gang luo fu-Kang LEI Xiang YAO Yun-Da LIAO Guo-Chao LIU Zhong-Qiu JIANG Zhi-Hong ZHOU Hua WU Peng Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of China International Institute for Translational Chinese MedicineGuangzhou University of Chinese MedicineGuangzhou 510006China School of Translational Chinese Medicine Guangdong Pharmaceutical UniversityGuangzhou 510006China State Key Laboratory of Quality Research in Chinese Medicine Macao University of Science and TechnologyMacao 999078China

Four new 3,4-seco-labdane diterpenoids,nudiflopenes J-M,were isolated from the leaves of Callicarpa nudiflora along with six known *** structures of these diterpenoids were determined by comprehensive spectroscopic *** the isolated compounds were evaluated for their inhibitory effects on NO production in LPS-stimulated RPMs and RAW264.7 *** results suggest that nudiflopenes J-M and other four known compounds showed significant inhibitory effects against NO production comparable to the positive control dexamethasone.

关键词： Callicarpa nudiflora Verbenaceae 3,4-seco-Labdane diterpenoid Anti-inflammatory RPMs RAW264.7

Kirschner wire migration from the right second rib to the right ventricle： a case report

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Traumatology 2013年第5期16卷 292-294页

作者： WANG Song BAO Zheng luo Ling-fu Department of Thoracic Surgery Affiliated NanhuaHospital University of South China Hengyang 421002China Department of Cardiac Surgery Second XiangyaHospital Central South University Changsha 410011China

Migrations of orthopedic wires to car- diovascular system are uncommon and rarely reported. We report a case of right ventricle embolization with the Kirschner wire that was used for right 2nd rib osteosynthesis 2 years and 8 months previously in a 50-year-old man. The patient was asymptomatic and migration of the Kirschner wire was discovered by routine chest X-ray. An 8 cm-long Kirschner wire was successfully retrieved from the right ventricle. The treatment strategy for Kirschner wire removal from right ventricle is discussed.

关键词： Bone wires Heart ventricles Rib fractures

Studies on the Inclusion Complex Reaction and Fluorescent Analytical Application of β- cyclodextrin with Hymecromone

在线全文

学校读者我要写书评

暂无评论

Wuhan University Journal of Natural Sciences 1999年第4期4卷 473-476页

作者： luo Zhao fu, SONG Wei, PAN Zu ting  College of Chemistry and Environmental Science, Wuhan University, Wuhan 430072, China Wuhan University College of Chemistry and Environmental Science Wuhan China (GRID:grid.49470.3e) (ISNI:***)

The inclusion complex reaction condition and the mechanism of β cyclodextrin with hymecromone have been studied by fluorescent spectrum. The fluorescent intensity and the stability of the system can be qreatly increased in qiven condition, and the formation constant of the inclusion complex reaction has been determined too. The system can be applied to the determination of trace amounts of hymecromone, the maximum fluorescent intensity is obtained with excitation and emission wavelength at 362 nm and 452 nm, respectively. The linear range for hymecromone is 8.0×10 -9 mol·L -1 to 1.0×10 -5 mol·L -1 . The detection limit is 1.8×10 -9 mol·L -1 . A simple, rapid and highly sensitive fluorimetric method is proposed for the determination of hymecromone. The results obtained are in agreement with those given by an official method.

关键词： Fluorescent spectra hymecromone β cyclodextrin inclusion complex

发展中大国的空间经济格局演变及其动因机制——基于中国和印度的比较分析

在线全文

学校读者我要写书评

暂无评论

亚太经济 2019年第1期 61-70,155页

作者：罗富政湖南师范大学商学院

以中国和印度为典型代表,对发展中大国的空间经济格局演变进行趋同度评价,并从要素配置、制度变迁、关系变迁三方面,分析发展中大国空间经济格局演变的动因机制。研究发现:中国空间经济格局在不断优化,其中要素配置机制和关系变迁机制... 详细信息

以中国和印度为典型代表,对发展中大国的空间经济格局演变进行趋同度评价,并从要素配置、制度变迁、关系变迁三方面,分析发展中大国空间经济格局演变的动因机制。研究发现:中国空间经济格局在不断优化,其中要素配置机制和关系变迁机制的作用显著,且随着优化程度的提升关系变迁机制的作用效应越来越强;印度区际经济发展的趋同性并不显著甚至出现区际分异,其中关系变迁机制是制约其空间经济格局优化的重要因素;中央和地方政府区域政策的合理性和有效性是形成中印空间经济格局演变动因机制作用差异的关键。

关键词：发展中大国空间经济格局演变动因机制

Z-2′-[1-(1,2,4-三唑)基]-O-(α-甲基对卤苄基)-2,4-二氯苯乙酮肟硝酸盐的合成

在线全文

学校读者我要写书评

暂无评论

精细化工 2001年第3期18卷 138-140页

作者：李再峰罗富英等浙江师范学院科技中心，广东湛江524048

以 2 ,4 二氯氯代苯乙酮、1,2 ,4 三唑和羟胺为原料 ,合成了Z 2′ [1 (1,2 ,4 三唑 )基 ] 2 ,4 二氯苯乙酮肟 (Ⅰ ) ,以对氯 (对溴 )苯乙酮合成对氯 (对溴 ) α 氯乙苯 (ⅡA 和ⅡB) ,Ⅰ分别与ⅡA和ⅡB 反应生成Z 2′ [1 (1,2 ,4 三唑 )... 详细信息

以 2 ,4 二氯氯代苯乙酮、1,2 ,4 三唑和羟胺为原料 ,合成了Z 2′ [1 (1,2 ,4 三唑 )基 ] 2 ,4 二氯苯乙酮肟 (Ⅰ ) ,以对氯 (对溴 )苯乙酮合成对氯 (对溴 ) α 氯乙苯 (ⅡA 和ⅡB) ,Ⅰ分别与ⅡA和ⅡB 反应生成Z 2′ [1 (1,2 ,4 三唑 )基 ] O (α 甲基对卤苄基 ) 2 ,4 二氯苯乙酮肟硝酸盐两个化合物 ,产率为 6 2 .5 %和 5 8.8% ,化合物结构经元素分析、IR和1HNMR确定。

关键词： Z-三唑基O-(α-甲基对卤苄基)-二氯苯乙酮肟硝酸盐 Z-三唑基-二氯苯乙酮肟对卤-α-氯乙苯

Horizontal gene transfer of a syp homolog contributes to the virulence of Burkholderia glumae

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2021年第12期20卷 3222-3229页

作者： WANG Sai WANG Pei-hong NIE Wen-han CUI Zhou-qi LI Hong-yu WU Yan Ayizekeranmu YIMING fu luo-yi Iftikhar AHMAD CHEN Gong-you ZHU Bo School of Agriculture and Biology Shanghai Jiao Tong University/Key Laboratory of Urban Agriculture of the Ministry of Agriculture and Rural AffairsShanghai 200240P.R.China Department of Plant Pathology&Ecology the Connecticut Agricultural Experiment StationNew Haven 06504CTUSA Department of Environmental Sciences COMSATS University IslamabadVehari-CampusVehari 61100Pakistan

Horizontal gene transfer(HGT)has been proved a major driving force in prokaryotic ***,the molecular functions of these transferred genes in pathogenic bacteria especially plant pathogenic bacteria are still not fully *** this study,the whole-genome in silico analysis was performed and found a syringopeptin synthetase(syp)homolog in Burkholderia glumae,which can cause bacterial panicle blight in rice,was predicted to be horizontally transferred from Pseudomonas ancestor with solid confidence by phylogenetic *** comprehensive molecular experiments were performed to study the potential role of this gene in *** of rice panicles with the syp mutant resulted in 60%lower disease index compared with the wild type(WT)parent strain,suggesting the requirement of syp for the full virulence of *** analysis of exudates from *** showed suppression of synthesis of metabolites analogous to syringopeptin in the *** these data raise the possibility of HGT phenomenon in shaping the virulence and adaptation of *** over evolutionary time.

关键词： horizontal gene transfer burkholderia glumae syringopeptin synthetase