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The recent advances in self-powered medical information sensors

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InfoMat 2020年第1期2卷 212-234页

作者： luming zhao HuLi Jianping Meng Zhou Li CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro-nano Energy and SensorBeijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijingChina School of Nanoscience and Technology University of Chinese Academy of SciencesBeijingChina School of Biological Science and Medical Engineering Beihang UniversityBeijingChina Center on Nanoenergy Research School of Physical Science and TechnologyGuangxi UniversityNanningChina

Monitoring various medical information distributed throughout the body is of great importance in early clinic diagnosis and treatment of *** discover abnormal medical signals and find their causes in good time,the human body should be monitored continuously and *** meet the requirements,various battery-less and self-powered information acquisition techniques are *** this review,the recent advances in self-powered medical information sensors(SMIS)with different functions,structure design,and electric performance are summarized and *** SMIS mainly involves triboelectric nanogenerator(TENG),piezoelectric nanogenerator(PENG),pyroelectric nanogenerator(PyNG)/thermoelectric generator(TEG)and solar ***,this review also analyzed the remaining challenges and prospected the development direction of SMIS in future.

关键词： medical information piezoelectric nanogenerator self-powered sensor solar cells thermoelectric generators triboelectric nanogenerator

Conductive nanomaterials for cardiac tissues engineering

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Engineered Regeneration 2020年第1期1卷 88-94页

作者： Wei Liu luming zhao Changyong Wang Jin Zhou Tissue Engineering Research Center Academy of Military Medical Sciences and Department of Neural Engineering and Biological Interdisciplinary StudiesInstitute of Military Cognition and Brain SciencesAcademy of Military Medical Sciences27 Taiping RdBeijing 100850PR China

Myocardial infarction(MI)is a worldwide disease with high incidence and high fatality *** the past decade,a lot of research work based on the method of cardiac tissues engineering has received wide attention from re-searchers and has been demonstrated to have important application prospects in the treatment of *** make engineered cardiac tissue(ECTs)simulate the characteristics of the natural myocardial microenvironment better,the unique electrophysiological characteristics of myocardial tissue should be ***,conductive nanomaterials are adopted to construct ECTs to make up for the lack of traditional scaffold *** this arti-cle,the research progresses of conductive nanomaterials application in the field of cardiac tissue engineering are summarized,and two treatment strategies of cardiac patch construction and injectable materials for MI treatment are discussed *** research work provided reference for the study of cardiac tissue engineering based conductive nanomaterials.

关键词： Myocardial infarction Cardiac tissues engineering Biomaterial Nanomaterials

Novel optical soliton molecules formed in a fiber laser with near-zero net cavity dispersion

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Light(Science & Applications) 2023年第2期12卷 272-283页

作者： Xiao Hu Jun Guo Jun Wang Jie Ma luming zhao Seongwoo Yoo Dingyuan Tang Julong College Shenzhen Technology University518118 ShenzhenChina School of Electrical and Electronic Engineering Nanyang Technological UniversitySingapore 639798Singapore jiangsu Key Laboratory of Laser Materials and Devices School of Physics and Electronic EngineeringJiangsu Normal UniversityXuzhouChina School of Optical and Electronic Information Huazhong University of Science and Technology430074 WuhanChina

Soliton molecules(SMs)are stable bound states between *** in fiber lasers are intensively investigated and embody analogies with matter *** experimental studies on SMs formed by bright solitons,including soliton-pair,soliton-triplet or even soliton-quartet molecules,are ***,study on soliton-binding states between bright and dark solitons is *** this work,the formation of such novel SMs in a fber laser with near-zero group velocity dispersion(ZGVD)is ***,these SMs are formed because of the incoherent cross-phase modulation of light and constitute a new form of SMs that are conceptually analog to the multi-atom molecules in *** research results could assist the understanding of the dynamics of large SM *** findings may also motivate potential applications in large-capacity transmission and all-optical information storage.

关键词： fiber optical laser

Multi-channel surface acoustic wave device and its application on all-fiber acousto-optic modulation

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Chinese Optics Letters 2010年第1期8卷 107-110页

作者：赵路明赵启大 Institute of Physics Nankai University Institute of Modern Optics Nankai University

The interaction of multi-channel surface acoustic waves （SAWs） and a guided optical wave in fiber is studied, and the corresponding coupled wave equations are derived. A novel two-channel SAW all-fiber acousto-optic... 详细信息

关键词： Acoustic waves Acoustics Acoustoelectric effects Wave equations

Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF,and the neutralization of miR-150 attenuate tumor development

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Protein & Cell 2013年第12期4卷 932-941页

作者： Yuchen Liu luming zhao Dameng Li Yuan Yin Chen-Yu Zhang Jing Li Yujing Zhang Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology State Key Laboratory of Pharmaceutical BiotechnologySchool of Life SciencesNanjing UniversityNanjing 210093China Oncology Institute Fourth Affiliated Hospital of Suzhou UniversityWuxi 214062China

Tumor-associated macrophages(TAMs)mostly exhibit M2-like(alternatively activated)properties and play posi-tive roles in angiogenesis and *** en-dothelial growth factor(VEGF)is a key angiogenic *** tumor development,TAMs secrete VEGF and other factors to promote angiogenesis;thus,anti-treatment against TAMs and VEGF can repress cancer development,which has been demonstrated in clinical trials and on an experimental *** the present work,we show that miR-150 is an oncomir because of its promotional effect on ***-150 targets TAMs to up-regulate their secre-tion of VEGF in *** the utilization of cell-derived vesicles,named microvesicles(MVs),we transferred an-tisense RNA targeted to miR-150 into mice and found that the neutralization of miR-150 down-regulates miR-150 and VEGF levels in vivo and attenuates ***-fore,we proposed the therapeutic potential of neutralizing miR-150 to treat cancer and demonstrated a novel,natu-ral,microvesicle-based method for the transfer of nucleic acids.

关键词： microvesicle miR-150 tumorigenesis VEGF neutralization attenuation

Passive harmonic mode locking of gain-guided solitons in erbium-doped fiber lasers

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Chinese Science Bulletin 2008年第5期53卷 676-680页

作者： zhao luming TANG DingYuan CHENG Tee Hiang TAM Hwa-Yaw LU Chao School of Electrical and Electronic Engineering Nanyang Technological University 639798 Singapore Department of Electrical Engineering Hong Kong Polytechnic University Hong Kong China Department of Electronic and Information Engineering Hong Kong Polytechnic University Hong Kong China

We report the experimental observation of passive harmonic mode locking of gain-guided solitons in erbium-doped fiber lasers either made of purely normal dispersion fibers or operating in the net normal cavity dispersion regime. Harmonic-2 and harmonic-3 mode locking states of the gain-guided solitons with supermode suppression larger than 35 dB have been obtained.

关键词：铒掺杂光纤激光器孤波被动谐波振荡型同步正常色散

Tunable and switchable harmonic h-shaped pulse generation in a 3.03 km ultralong mode-locked thulium-doped fiber laser

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Photonics Research 2019年第3期7卷 332-340页

作者： JUNQING zhao LEI LI luming zhao DINGYUAN TANG DEYUAN SHEN LEI SU Jiangsu Key Laboratory of Advanced Laser Materials and Devices Jiangsu Collaborative Innovation Center of Advanced Laser Technology and Emerging IndustrySchool of Physics and Electronic EngineeringJiangsu Normal University School of Engineering and Materials Science Queen Mary University of London

We experimentally demonstrated a type of tunable and switchable harmonic h-shaped pulse generation in a thulium-doped fiber(TDF) laser passively mode locked by using an ultralong nonlinear optical loop *** total cavity length was ～3.03 km, the longest ever built for a TDF laser to our best knowledge, which resulted in an ultralarge anomalous dispersion over -200 ps^2 around the emission wavelength. The produced h-shaped pulse can operate either in a fundamental or in a high-order harmonic mode-locking(HML) state depending on pump power and intra-cavity polarization state(PS). The pulse duration, no matter of the operation state, was tunable with pump power. However, pulse breaking and self-organizing occurred, resulting in high-order HML,when the pump power increased above a threshold. At a fixed pump power, the order of HML was switchable from one to another by manipulating the PS. Switching from the 8 th up to the 48 th order of HML was achieved with a fixed pump power of ～4.15 W. Our results revealed the detailed evolution and switching characteristics of the HML and individual pulse envelope with respect to both the pump power and PS. We have also discussed in detail the mechanisms of both the h-shaped pulse generation and the switching of its HML. This contribution would be helpful for further in-depth study on the underlying dynamics of long-duration particular-envelope pulses with ultralarge anomalous dispersion and ultralong roundtrip time.

关键词： ultralong mode-locked thulium-doped fiber laser switchable harmonic

A Hybrid Biofuel and Triboelectric Nanogenerator for Bioenergy Harvesting

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Nano-Micro Letters 2020年第4期12卷 53-64页

作者： Hu Li Xiao Zhang luming zhao Dongjie Jiang Lingling Xu Zhuo Liu Yuxiang Wu Kuan Hu Ming‑Rong Zhang Jiangxue Wang Yubo Fan Zhou Li Beijing Advanced Innovation Centre for Biomedical Engineering Key Laboratory for Biomechanics and Mechanobiology of Chinese Education MinistrySchool of Biological Science and Medical EngineeringBeihang UniversityBeijing 100083People’s Republic of China CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro‑Nano Energy and SensorBeijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijing 100083People’s Republic of China School of Nanoscience and Technology University of Chinese Academy of SciencesBeijing 100049People’s Republic of China School of Physical Education Jianghan UniversityWuhan 430056People’s Republic of China Center on Nanoenergy Research School of Physical Science and TechnologyGuangxi UniversityNanning 530004People’s Republic of China Department of Radiopharmaceuticals Development National Institute of Radiological SciencesNational Institutes for Quantum and Radiological Science and TechnologyChiba 263‑8555Japan

Various types of energy exist everywhere around us,and these energies can be harvested from multiple sources to power micro-/nanoelectronic system and even personal electronic *** this work,we proposed a hybrid energy-harvesting system(HEHS)for potential in vivo *** HEHS consisted of a triboelectric nanogenerator and a glucose fuel cell for simultaneously harvesting biomechanical energy and biochemical energy in simulated body *** two energy-harvesting units can work individually as a single power source or work simultaneously as an integrated *** design strengthened the flexibility of harvesting multiple energies and enhanced corresponding electric *** with any individual device,the integrated HEHS outputs a superimposed current and has a faster charging *** the harvested energy,HEHS can power a calculator or a green light-emitting diode *** the widely existed biomechanical energy and glucose molecules in the body,the developed HEHS can be a promising candidate for building in vivo self-powered healthcare monitoring system.

关键词： Self-powered Triboelectric nanogenerator Glucose fuel cell Hybrid energy harvester Bioenergy

管窥百年普利策:基于普利策新闻奖嘉奖辞的词频分析(1917-2016)

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国际新闻界 2017年第12期39卷 88-105页

作者：申琦赵鹿鸣华东师范大学传播学院

本研究通过词频分析法,考察1917年至2016年美国普利策新闻奖获作品的嘉奖辞。研究发现,作为普利策评审委员会对获奖作品的专业评述,一百年来嘉奖词中的词频呈现一定的稳定性和持续性;同时,在不同总统和不同政党的执政期内,嘉奖词中的词... 详细信息

本研究通过词频分析法,考察1917年至2016年美国普利策新闻奖获作品的嘉奖辞。研究发现,作为普利策评审委员会对获奖作品的专业评述,一百年来嘉奖词中的词频呈现一定的稳定性和持续性;同时,在不同总统和不同政党的执政期内,嘉奖词中的词频又显现出差异性。这在某种程度上表明,百年来普利策新闻奖评审遵循并适当调整着自己的专业标准,由此影响普利策新闻奖这一美国新闻业最高荣誉体系的构建。

关键词：普利策新闻奖嘉奖辞词频分析法