检索结果-南通市图书馆

Chromosome-level genome and population genomics of the intermediate horseshoe bat(Rhinolophus affinis)reveal the molecular basis of virus tolerance in Rhinolophus and echolocation call frequency variation

引用

Zoological Research 2024年第5期45卷 1147-1160页

作者： Le Zhao Jiaqing Yuan Guiqiang Wang Haohao Jing Chen Huang lulu xu Xiao xu Ting Sun Wu Chen Xiuguang Mao Gang Li College of Life Sciences Shaanxi Normal UniversityXi’anShaanxi 710119China QinLing-Bashan Mountains Bioresources Comprehensive Development C.I.C. School of Bioscience and EngineeringShaanxi University of TechnologyHanzhongShaanxi 723001China Guangzhou Zoo GuangzhouGuangdong 510070China School of Ecological and Environmental Sciences East China Normal UniversityShanghai 200241China

Horseshoe bats(genus Rhinolophus,family Rhinolophidae)represent an important group within chiropteran phylogeny due to their distinctive traits,including constant high-frequency echolocation,rapid karyotype evolution,and unique immune *** in evolutionary biology,supported by high-quality reference genomes and comprehensive whole-genome data,have significantly enhanced our understanding of species origins,speciation mechanisms,adaptive evolutionary processes,and phenotypic ***,genomic research and understanding of the evolutionary patterns of Rhinolophus are severely constrained by limited data,with only a single published genome of *** currently *** this study,we constructed a high-quality chromosome-level reference genome for the intermediate horseshoe bat(***).Comparative genomic analyses revealed potential genetic characteristics associated with virus tolerance in ***,we observed expansions in several immune-related gene families and identified various genes functionally associated with the SARS-CoV-2 signaling pathway,DNA repair,and apoptosis,which displayed signs of rapid *** addition,we observed an expansion of the major histocompatibility complex class II(MHC-II)region and a higher copy number of the HLA-DQB2 gene in horseshoe bats compared to other chiropteran *** on whole-genome resequencing and population genomic analyses,we identified multiple candidate loci(e.g.,GLI3)associated with variations in echolocation call frequency across *** *** research not only expands our understanding of the genetic characteristics of the Rhinolophus genus but also establishes a valuable foundation for future research.

关键词： Reference-quality genome Comparative genomics Population genomics Positive selection Bats

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Correlation between radiologic features on contrastenhanced CT and pathological tumor grades in pancreatic neuroendocrine neoplasms

引用

The Journal of Biomedical Research 2021年第3期35卷 179-188页

作者： Wenbin xu Han Yan lulu xu Mingna Li Wentao Gao Kuirong Jiang Junli Wu Yi Miao Pancreas Center the First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Pancreas Institute of Nanjing Medical University NanjingJiangsu 210029China Department of Radiology the First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Department of Pathology the First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China

Contrast-enhanced computed tomography(CT)contributes to the increasing detection of pancreatic neuroendocrine neoplasms(PNENs).Nevertheless,its value for differentiating pathological tumor grades is not well *** this report,we have conducted a retrospective study on the relationship between the 2017 World Health Organization(WHO)classification and CT imaging features in 94 *** of the investigated features eventually provided statistically significant indicators for discerning PNENs G3 from PNENs G1/G2,including tumor size,shape,margin,heterogeneity,intratumoral blood vessels,vascular invasion,enhancement pattern in both contrast phases,enhancement degree in both phases,tumor-to-pancreas contrast ratio in both phases,common bile duct dilatation,lymph node metastases,and liver ***-defined tumor margin was an independent predictor for PNENs G3 with the highest area under the curve(AUC)of 0.906 in the multivariable logistic regression and receiver operating characteristic curve *** portal enhancement ratio(PER)was shown the highest AUC of 0.855 in terms of quantitative *** data suggest that the traditional contrastenhanced CT still plays a vital role in differentiation of tumor grades and heterogeneity analysis prior to treatment.

关键词： pancreatic neuroendocrine neoplasm computed tomography tumor grade heterogeneity analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Design and experiment of the soil-covering and soil-compacting device for seedling raising and sowing of trough type panax notoginseng

引用

International Journal of Agricultural and Biological Engineering 2023年第5期16卷 113-122页

作者： Wencai Yang Wang Pu lulu xu Ziyuan Tian Jing Zhao Yijie Zhang Zhenjie Yang College of Mechanical and Electrical Engineering Yunnan Agricultural UniversityKunming 650201China Agricultural and rural Bureau Southwest Guizhou 562499China

In order to improve the seedling quality of Panax notoginseng,combined with the special agronomic requirements of Panax notoginseng,a sharp angle roller soil-covering and soil-compacting device integrating the functions of soil-covering and soil-compacting was *** on the theoretical analysis of seed ditch conditions,soil-covering process and soilcompacting process,the structure of soil-covering and soil-compacting device was *** theoretical analysis and calculation,the diameter and length of soil-covering and soil-compacting wheel were 20 cm and 10.7-14.1 cm,respectively,the sharp angle and height range were 45°-105°and 0.8-1.6 cm respectively,and the spring stiffness was 38.54 N/mm;Using the discrete element method to simulate the soil-covering and soil-compacting process,it was obtained that when the sharp angle range was 60°-90°,the sharp angle height range was 0.8-1.2 cm,and the soil-covering effect was better;Taking the forward speed,ballast pressure,sharp angle and sharp angle height of the planter as the test factors,and taking the soil-covering thickness,grain spacing and soil compactness as the indexes,the four factor and three-level Box-Behnken Design test was carried *** response surface test analysis method was used to establish the regression equation between the factors and indexes,and determine the best parameter combination:the forward speed was 6.5 m/min,the ballast pressure was 360.5 N,the sharp angle was 67°,and the sharp angle height was 1 cm,at this time,the soil-covering thickness was 0.64 cm,the grain spacing was 5.03 cm,and the soil compactness was 321.77 *** to the soil trough test,the design of soil-covering and soil-compacting device met the agronomic requirements of plant spacing,soil-compactness and soil-covering thickness during seedling sowing of Panax *** research results can provide a reference for the design of Panax notoginseng seedling planter integrating pressing hole(ditching),so

关键词： Panax notoginseng trough type seedling raising and sowing soil-covering and soil-compacting EDEM test

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Simultaneous determination of 35 constituents and elucidation of effective constituents in a multi-herb Chinese medicine formula Xiaoer-Feire-Kechuan

引用

Journal of Pharmaceutical Analysis 2021年第6期11卷 717-725页

作者： Zhanpeng Shang lulu xu Yi Kuang Yan Lin Shuang Liu Long Sun Tao Bo Min Ye xue Qiao State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China School of Pharmaceutical Sciences Guizhou Medical UniversityGuizhou550025China Thermo Fisher Scientific Beijing100102China

Xiaoer-Feire-Kechuan(XFK) is an 11-herb Chinese medicine formula to treat cough and pulmonary *** complicated composition rendered its chemical analysis and effective-component *** this study,we combined quantitative analysis and bioactivity test to reveal the antiinflammatory constituents of ***,UPLC-DAD and UHPLC/Q-Orbitrap-MS methods were established and validated to quantify 35 analytes(covering 9 out of 11 herbs) in different XFK *** reaction monitoring mode built in Q-Orbitrap-MS was used to improve the sensitivity and ***,anti-inflammatory activities of the 35 analytes were analyzed using in vitro COX-2 inhibition ***,major analytes forsythosides H,I,A(8-10),and baicalin(15)(total contents varied from 21.79 to 91.20 mg/dose in different formulations) with significant activities(inhibitory rate ≥ 80%) were proposed as the anti-inflammatory constituents of *** present study provided an effective strategy to discover effective constituents of multi-herb formulas.

关键词： Multi-herb formulas Effective constituents Xiaoer-Feire-Kechuan formula(XFK) Parallel reaction monitoring(PRM) Cyclooxygenase-2(COX-2)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Waste Textile Reutilization Via a Scalable Dyeing Technology: A Strategy to Enhance Dyestuffs Degradation Efficiency

引用

Advanced Fiber Materials 2022年第6期4卷 1595-1608页

作者： Heng Zhai Zekun Liu lulu xu Ting Liu Yangyang Fan Lu Jin Ruihan Dong Yangpeiqi Yi Yi Li Department of Materials University of ManchesterOxford RoadManchester M139PLUK

The rapid expansion of the fast fashion industry brings about environmental concerns such as dyestuffs-related water pollutions and waste *** wastewater-disposal strategies emphasize the optimization of photocatalytic activity to improve pollutant degradation efficiency,while the absorptivity,recyclability and sustainability of photocatalysts are always *** overproduced textiles are still in urgent of being recycled and reutilized in eco-friendly *** this work,a scalable dyeing technology is employed to achieve green and sustainable reutilization of waste *** functionalized TiO2/reduced graphene oxide wool fabrics show excellent sustainability,remarkable adsorbing capacity and enhanced photocatalytic *** taking advantage of these properties,we develop an integrated strategy of nighttime adsorption and day-time photodegradation which could significantly optimize the dyestuffs degradation *** concept of waste textiles reutilization and wastewater treatment in this work provides practical potential for efficient and sustainable environmental remediation.

关键词： Waste textile reutilization Wastewater treatment Adsorption Photocatalysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geological controls of shale gas accumulation and enrichment mechanism in Lower Cambrian Niutitang Formation of western Hubei, Middle Yangtze, China

引用

Frontiers of Earth Science 2021年第2期15卷 310-331页

作者： lulu xu Saipeng HUANG Zaoxue LIU Yaru WEN Xianghui ZHOU Yanlin ZHANG Xiongwei LI Deng WANG Fan LUO Cheng CHEN Hubei Geological Survey WuhanHubei 430034China Key Laboratory of Continental shale Accumulation and Development of Ministry of Education Northeast Petroleum UniversityDaqing 163318China Coal Reservoir Laboratory of National Engineering Research Center of CBM Development&Utilization School of Energy ResourcesChina University of GeosciencesBeijing 100083China The Seventh Geological Brigade of Hubei Geological Bureau Yichang 443000China

The lower Cambrian Niutitang Formation is of crucial importance for shale gas target reservoirs in western Hubei,China;however,little work has been done in this field,and its shale gas accumulation and enrichment mechanism are still *** on survey wells,outcrop data,and large numbers of tests,the geological conditions of shale gas accumulation were studied;moreover,the factors that influence the gas content were thoroughly *** results show that the Niutitang Formation(Є1n)can be divided into three sections:the first section(Є_(1)n^(1)),the second section(Є_(1)n^(2)),and the third section(Є1n3).TheЄ_(1)n^(2) is the main shale gas *** deep shelf facies is the main sedimentary facies and can be divided into three main lithofacies:argillaceous siltstone,carbonaceous shale and carbonaceous siliceous *** total organic carbon(TOC)content shows gentle growth trends until bottom of theЄ_(1)n^(2) and then decreases rapidly within theЄ_(1)n^(1),and the TOC content mainly ranges from 2%to 4%*** calcite and dolomite dissolution pores,clay intergranular pores and organic pores are the main pore types and the micropore types are clearly related to the mineral compositions and the TOC ***,the gas content is mainly affected by the TOC ***,wells with high gas contents are distributed only southeast of the Huangling anticline,and the combination of structural styles,fault and fracture development,and the distribution of the regional unconformity boundary between the upper Sinian Dengying Formation(Z2d)and theЄ_(1)n^(2) are the three most important factors affecting the gas *** favorable areas must meet the following conditions:a deep shelf environment,the presence of theЄ_(1)n^(1),wide and gentle folds,far from large normal faults that are more than 5 km,moderate thermal evolution,and greater than 500 m burial depth;this includes the block with the YD2–ZD2 wells,and the block with the Y1 and YD4 wel

关键词： shale gas Niutitang Formation accumulation conditions factors influencing the gas content sedimentary facies

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characterization of natural fractures in deep-marine shales: a case study of the Wufeng and Longmaxi shale in the Luzhou Block Sichuan Basin, China

引用

Frontiers of Earth Science 2023年第1期17卷 337-350页

作者： Shasha SUN Saipeng HUANG Enrique GOMEZ-RIVAS Albert GRIERA ΒοLIU lulu xu Yaru WEN Dazhong DONG Zhensheng SHI Yan CHANG Yin XING PetroChina Research Institute of Petroleum Exploration&Development Beijing 100083China Key Laboratory of Continental Shale Hydrocarbon Accumulation and Efficient Development Ministry of EducationNortheast Petroleum UniversityDaqing 163318China Departament de Mineralogia Petrologia i Geologia AplicadaFacultat de Ciències de la TerraUniversitat de Barcelona(UB)c/Martíi Franquès s/nBarcelona 08028Spain Departament de Geologia Universitat Autònoma de BarcelonaBellaterra 08193Cerdanyola del VallèsSpain Hubei Geological Survey Wuhan 430034China School of Geography Science and Geomatics Engineering Suzhou University of Science and TechnologySuzhou 215009China

Natural fractures are of crucial importance for oil and gas reservoirs,especially for those with ultralow permeability and *** deep-marine shale gas reservoirs of the Wufeng and Longmaxi Formations are typical targets for the study of natural fracture *** descriptions of full-diameter shale drill core,together with 3D Computed Tomography scans and Formation MicroScanner Image data acquisition,were carried out to characterize microfracture morphology in order to obtain the key parameters of natural fractures in such *** fracture type,orientation,and their macroscopic and microscopic distribution features are *** results show that the natural fracture density appears to remarkably decrease in the Wufeng and Longmaxi Formations with increasing the burial *** trends have been observed for fracture length and ***,the natural fracture density diminishes as the formation thickness *** are three main types of natural fractures,which we interpret as(I)mineral-filled fractures(by pyrite and calcite),i.e.,veins,(II)those induced by tectonic stress,and(III)those formed by other processes(including diagenetic shrinkage and fluid overpressure).Natural fracture orientations estimated from the studied natural fractures in the Luzhou block are not consistent with the present-day stress *** difference in tortuosity between horizontally and vertically oriented fractures reveals their morphological *** addition,natural fracture density,host rock formation thickness,average total organic carbon and effective porosity are found to be important factors for evaluating shale gas *** study also reveals that the high density of natural fractures is decisive to evaluate the shale gas *** results may have significant implications for evaluating favorable exploration areas of shale gas reservoirs and can be applied to optimize hydraulic fracturing for permeability enhancement.

关键词： marine shale natural fracture filled fracture tortuosity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

各向异性增材制造构件的超声阵列全聚焦成像

引用

北京航空航天大学学报 2023年第5期49卷 1063-1070页

作者：徐娜许路路何方成中国航发北京航空材料研究院北京100095 中国航空发动机集团材料检测与评价重点实验室北京100095 航空材料检测与评价北京市重点实验室北京100095 北京航空航天大学材料科学与工程学院北京100191

针对激光增材制造构件的各向异性特征,开展超声波传播特性研究,并基于群速度测量结果对常规超声阵列全聚焦成像算法进行优化。采用CIVA超声仿真软件对含有横通孔和平底孔缺陷的试样开展全聚焦仿真研究,结果表明,材料的各向异性对超声阵... 详细信息

针对激光增材制造构件的各向异性特征,开展超声波传播特性研究,并基于群速度测量结果对常规超声阵列全聚焦成像算法进行优化。采用CIVA超声仿真软件对含有横通孔和平底孔缺陷的试样开展全聚焦仿真研究,结果表明,材料的各向异性对超声阵列全聚焦检测的成像质量、缺陷定位精度和缺陷分布范围均具有明显影响;开展全聚焦成像检测实验,结果表明,优化后的全聚焦成像算法能够实现激光增材制造钛合金试样中直径0.8 mm平底孔缺陷的准确检测,成像阵列性能指标(API)值减小至0.43,缺陷定位误差缩小至0.54 mm,检测能力和定位精度显著提高。

关键词：激光增材制造各向异性超声阵列全聚焦 CIVA仿真

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The need analysis of backbone civilian nurses post-oriented education training in China

引用

中西医结合护理（中英文） 2016年第8期2卷 1-6页

作者： CHEN zhaoyun 张银玲 GE Wei xu lulu YANG Qian School of Nurse Fourth Military Medical UniversityXi'anShaanxi710032 No.11 Hospital of PLA YiningXinjiang835000 Urumqi General Hospital of Xinjiang Military Area Command of PLA UrumqiXinjiang830000

To learn about the need of post-oriented education training of backbone civilian nurses,and to provide scientific evidence for the promotion of training. Methods The convenience sampling method was performed,and an anonymous survey on 324 nurses who participated in the "backbone civilian nurses training program"from September 2013 to October 2015 was carried out by using self-made ***(1)Among the 324 nurses,12. 04% of them volunteered to participate in the training and 87. 96%were sent by their departments.(2)More than 90% of training contents met their needs.(3)The training methods in demand included theoretical classroom teaching,clinical observation and probation,seminars,clinical management practice,clinical problem discussion and clinical nursing practice(4)The training period suggested by most nurses was about 2 to 4 weeks. Conclusion It is important to strengthen the significance of post-oriented education training and to improve the quality and capacity of civilian through scientific education design and practical training programs.

关键词： civilian nurse backbone continuing education training need

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

配戴角膜塑形镜早期角膜高阶像差变化及其影响因素

引用

中华实验眼科杂志 2020年第2期38卷 101-108页

作者：张旭王雁徐路路天津医科大学眼科临床学院天津市眼科医院天津市眼科学与视觉科学重点实验室300020 保定鹰华眼科医院保定071000

目的观察近视患者配戴角膜塑形镜早期角膜前后表面高阶像差的变化特点及其影响因素。方法采用系列病例观察研究设计。连续收集2018年1—4月在保定鹰华眼科医院成功验配角膜塑形镜的近视患者46例46眼,分别进行戴镜前及戴镜后1个月的角膜... 详细信息

目的观察近视患者配戴角膜塑形镜早期角膜前后表面高阶像差的变化特点及其影响因素。方法采用系列病例观察研究设计。连续收集2018年1—4月在保定鹰华眼科医院成功验配角膜塑形镜的近视患者46例46眼,分别进行戴镜前及戴镜后1个月的角膜像差、角膜离心率e值测量。应用Pentacam三维眼前节分析仪测量并分析角膜形态,记录6 mm内角膜前后表面鼻侧、颞侧、上方、下方各方向e值,Zernike分析计算以角膜顶点为中心6 mm直径范围内的前表面、后表面和全角膜Z33、Z3-3、Z31、Z3-1和Z40值。结果配戴角膜塑形镜后,角膜前表面和全角膜水平彗差、垂直彗差和球差的值向正向漂移,角膜后表面水平彗差、球差的值向负向漂移,与戴镜前比较差异均有统计学意义(均P<0.05)。戴镜前eNf、eTf、eIf、eSf、eMf分别为0.580(0.450,0.670)、0.455(0.378,0.513)、0.485(0.268,0.553)、0.665(0.578,0.740)、0.505±0.015,戴镜后分别为0.285(-0.635,0.665)、-0.605(-0.813,-0.335)、-0.545(-0.765,0.305)、-0.335(-0.705,0.423)、-0.247±0.058,戴镜后各个方向角膜前表面由陡峭变为平坦,与戴镜前比较差异均有统计学意义(均P<0.05)。多元逐步线性回归分析结果显示,配戴角膜塑形镜后全角膜球差与角膜e值、初始屈光度均呈中度负相关(rs=-0.626、-0.450,均P<0.05),水平彗差与颞侧e值中度负相关(rs=-0.391,P=0.004);戴镜后角膜前表面球差与角膜e值、初始屈光度呈中度负相关(rs=-0.612、-0.432,均P<0.05),水平彗差与颞侧e值中度负相关(rs=-0.400,P=0.003);戴镜后角膜后表面水平彗差与角膜前表面水平彗差呈负相关(rs=-0.380,P=0.009)。结论配戴角膜塑形镜后,全角膜和前表面球差、彗差正向漂移;角膜后表面球差、水平彗差负向漂移。戴镜前屈光度和角膜前表面变化大小是引起角膜高阶像差变化的重要影响因素。

关键词：近视/治疗角膜塑形镜高阶像差角膜e值

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：