检索结果-南通市图书馆

医护一体化专项管理在冠心病经皮冠状动脉介入术中的干预效果及对自我管理水平的影响研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

智慧健康 2024年第13期10卷 181-184页

作者：魏露露广州市第一人民医院广东广州510180

目的探讨医护一体化专项管理在冠心病经皮冠状动脉介入术中的干预效果及对自我管理水平的影响。方法选择2021年9月—2022年10月本院收治的150例冠心病患者为研究对象,所有患者均采用经皮冠状动脉介入术治疗,采用随机数字表法分为对照组... 详细信息

目的探讨医护一体化专项管理在冠心病经皮冠状动脉介入术中的干预效果及对自我管理水平的影响。方法选择2021年9月—2022年10月本院收治的150例冠心病患者为研究对象,所有患者均采用经皮冠状动脉介入术治疗,采用随机数字表法分为对照组和观察组,每组75例。其中,对照组采用常规方法护理,观察组联合医护一体化专项管理,两组均完成1周护理,比较两组健康信念、自我管理水平及依从性。结果两组护理1周后自我管理水平得到提高;观察组疾病管理、情绪认知管理及日常生活管理得分高于对照组,组间差异有统计学意义(P<0.05);观察组干预1周后按时服药、定期复查、饮食控制、适当运动及康复锻炼依从性高于对照组,组间差异有统计学意义(P<0.05)。结论医护一体化专项管理用于冠心病经皮冠状动脉介入术中,能提高患者健康信念和自我管理水平,可获得较高的依从性,值得推广应用。

关键词：医护一体化专项管理冠心病经皮冠状动脉介入术干预效果自我管理

2个海拔梯度种源鬼箭锦鸡儿根际土壤细菌对温度变化的响应

在线全文

学校读者我要写书评

暂无评论

草业科学 2024年第7期41卷 1632-1644页

作者：张隆安徐婷婷魏庐潞马周娟马飞宁夏大学生态环境学院宁夏银川750021 宁夏大学西北土地退化与生态恢复国家重点实验室培育基地宁夏银川750021 宁夏大学生命科学学院宁夏银川750021

根际土壤微生物与植物的生态适应密切相关,研究植物根际微生物多样性和群落结构对环境变化的响应有助于更好地理解植物生态适应机制。本研究以不同海拔梯度(2950和3530 m)鬼箭锦鸡儿(Caragana jubata)实生幼苗为研究对象,比较分析了其... 详细信息

根际土壤微生物与植物的生态适应密切相关,研究植物根际微生物多样性和群落结构对环境变化的响应有助于更好地理解植物生态适应机制。本研究以不同海拔梯度(2950和3530 m)鬼箭锦鸡儿(Caragana jubata)实生幼苗为研究对象,比较分析了其在不同温度(10和25℃)下的根系功能性状、根际土壤细菌多样性和群落结构差异。结果表明:温度变化显著影响了海拔2950 m种源鬼箭锦鸡儿根际土壤细菌的Chao1指数(P<0.05),但对海拔3530 m种源鬼箭锦鸡儿根际土壤细菌的Chao1和Shannon指数影响不显著;主坐标分析表明温度变化显著改变了海拔2950 m种源鬼箭锦鸡儿根际土壤细菌的群落结构(r=0.53,P<0.05),且与25℃温度处理相比,10℃显著增加了海拔2950 m种源的放线菌门(Actinobacteria)和假单胞菌属(Pseudomonas),以及海拔3530 m种源的Kapabacteria、纤维菌属(Cellvibrio)、Glutamicibacter、微杆菌属(Microbacterium)和诺卡菌属(Nocardia)的相对丰度(P<0.05)。同时,温度变化显著降低了海拔2950 m种源鬼箭锦鸡儿的根表面积、根尖数、根平均直径、根体积和根长(P<0.05),但是仅对海拔3530 m种源的根平均直径影响显著。Mantel检验表明,海拔2950 m种源鬼箭锦鸡儿根际土壤细菌群落结构受温度、根长和根平均直径影响显著(P<0.05),而海拔3530 m种源根际土壤菌群结构受温度、根体积、根表面积和根平均直径影响显著(P<0.05)。本研究发现,不同海拔梯度种源鬼箭锦鸡儿根际细菌多样性和群落结构以及根系性状对温度变化的响应存在差异,而且根系性状与其根际细菌的群落构建显著相关。

关键词：鬼箭锦鸡儿海拔种源土壤细菌群落结构多样性根系性状温度

基于SVM-DT-MLP模型的Web日志异常流量检测研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

现代信息科技 2024年第4期8卷 171-174,179页

作者：魏璐露程楠楠江西科技学院信息工程学院江西南昌330029

随着Web应用程序的普及,网络攻击和安全漏洞的风险日益增加。Web日志文件详细记录了网站运行信息,对日志中的流量进行分类从而检测出异常攻击流量是保障网页长期提供稳定、安全服务行之有效的方法之一。文中将Voting特征选择与Stacking... 详细信息

随着Web应用程序的普及,网络攻击和安全漏洞的风险日益增加。Web日志文件详细记录了网站运行信息,对日志中的流量进行分类从而检测出异常攻击流量是保障网页长期提供稳定、安全服务行之有效的方法之一。文中将Voting特征选择与Stacking集成相结合,构建了SVM-DT-MLP模型,并将其用于Web日志异常流量检测。测试结果表明,SVM-DT-MLP模型的性能显著优于单一算法模型,其Precision(精确度)达到92.44%,Recall(召回率)达到92.43%,F1-Score(F1值)达到92.44%。这意味着该模型能够有效地检测出异常攻击流量,并在保障网页提供稳定和安全服务方面具有很好的效果。

关键词： Web日志异常流量检测 Stacking集成 Voting特征选择机器学习

中国设施土壤重金属累积特征与污染阻控技术研究进展

在线全文

学校读者我要写书评

暂无评论

农业工程学报 2024年第9期40卷 1-14页

作者：王子豪梁红怡张冬寒李龙城魏露露万亚男陈清中国农业大学资源与环境学院农田土壤污染防控与修复北京市重点实验室北京100193

长期集约化耕作导致中国设施土壤重金属累积和面源污染风险增加的状况已引起广泛关注。该研究总结了中国设施土壤重金属累积状况及其来源,发现长期盲目投入肥料及农药是引发设施菜田土壤重金属累积问题的主要原因。目前,设施土壤重金属... 详细信息

长期集约化耕作导致中国设施土壤重金属累积和面源污染风险增加的状况已引起广泛关注。该研究总结了中国设施土壤重金属累积状况及其来源,发现长期盲目投入肥料及农药是引发设施菜田土壤重金属累积问题的主要原因。目前,设施土壤重金属累积呈现出广泛性和中轻度污染特征,其中镉是主要的污染元素。遵循面源污染治理中“源头预控-过程阻断-末端修复”原则,基于国内外文献综述,该文总结归纳出适用于设施土壤重金属累积特征与污染的联合阻控技术及作用机制。首先在灌溉和肥药投入等源头环节减少重金属输入;其次在作物种植过程中,通过选用重金属低积累特性的蔬菜种类或品种,结合水肥一体化施用大分子有机水溶性肥料或叶面喷施具有阻控重金属作用的营养型阻控剂,抑制作物吸收重金属;最后在末端修复环节,利用具有多元功能的土壤改良剂或微生物菌剂进行土壤钝化修复,或采用具有超重金属富集能力且能提高设施土壤生物多样性的植物作为填闲作物,实现生物修复的目标。该联合阻控技术的原则在于协同考虑污染防治、土壤改良、减肥增效等农学和环境目标,集成土壤修复与改良、水肥一体化、填闲作物栽培等技术,并兼顾设施土壤重金属污染修复工程所面临的投入品成本较高、经济效益不明显、缺失可持续改良导致效果不稳定等问题,优推能够钝化重金属并改良土壤的多功能土壤改良剂以及具有阻控重金属吸收、提高作物抗逆性的多功能有机水溶性肥料。上述措施能解决设施土壤普遍存在的重金属累积问题,提升土壤的安全生产能力,可为设施农业可持续发展提供更有效的技术支撑。

关键词：设施土壤重金属累积污染阻控土壤改良多功能土壤改良剂多功能有机水溶肥

同方期刊数据库

星型-三角形负泊松比结构的面内压缩刚度可调控特性

在线全文

学校读者我要写书评

暂无评论

振动与冲击 2024年第4期43卷 105-114页

作者：魏路路许世维朱国华赵轩西安建筑科技大学机电工程学院西安710055 长安大学汽车运输安全保障技术交通行业重点实验室西安710064

通过准静态面内压缩试验揭示星型-三角形结构(star-triangular honeycomb, STH)的刚度可调控特性。利用有限元模拟的方法研究非均匀壁厚STH的面内压缩刚度可调控机制,分析不同类型胞壁厚度比(t_(1)=t_(3))/t_(2)及胞壁角对其面内压缩刚... 详细信息

通过准静态面内压缩试验揭示星型-三角形结构(star-triangular honeycomb, STH)的刚度可调控特性。利用有限元模拟的方法研究非均匀壁厚STH的面内压缩刚度可调控机制,分析不同类型胞壁厚度比(t_(1)=t_(3))/t_(2)及胞壁角对其面内压缩刚度的影响。结果表明,STH在面内压缩载荷下呈2个线弹性阶段,且强化刚度比初始刚度显著增大。适当地增大内凹胞壁和垂直胞壁的厚度可同时提高STH的初始刚度及强化刚度;当(t_(1)=t_(3))/t_(2)>1.575后,初始刚度仍持续增大,而强化刚度反而逐渐减小,最终不再具有强化刚度阶段。胞壁角α≤30°时,增大胞壁角可提高STH的初始刚度及强化刚度,反之,初始刚度及强化刚度对应的应变随胞壁角的增大逐渐增大,而强化刚度逐渐减小并趋于消失。该研究将为可调节刚度负泊松比结构的设计提供新的思路。

关键词：星型-三角形结构(STH) 负泊松比可调控刚度非均匀壁厚准静态压缩

Understory seedlings of Quercus mongolica survive by phenological escape

在线全文

学校读者我要写书评

暂无评论

Forest Ecosystems 2024年第2期11卷 236-246页

作者： Shixiong Wu Ying Liu lulu He wei Zeng Qijing Liu College of Forestry Beijing Forestry UniversityBeijing100083China

Understanding understory seedling regeneration mechanisms is important for the sustainable development of temperate primary forests in the context of increasingly intense climate warming *** poor regeneration of dominant tree species,however,is one of the biggest challenges it faces at the ***,the regeneration of the shade-intolerant Quercus mongolica seedling is difficult in primary forests,which contrasts with the extreme abundance of understory seedlings in secondary *** mechanism behind the interesting phenomenon is still *** study used in-situ monitoring and nursery-controlled experiment to investigate the survival rate,growth performance,as well as nonstructural carbohydrate (NSC) concentrations and pools of various organ tissues of seedlings for two consecutive years,further analyze the understory light availability and simulate the foliage carbon (C) gain in the secondary and primary *** suggested that seedlings in the secondary forest had greater biomass allocation aboveground,height and specific leaf area (SLA) in summer,which allowed the seedling to survive longer in the canopy closure *** light availability and positive C gain in early spring and late autumn are key factors affecting the growth and survival of understory seedlings in the secondary forest,whereas seedlings in the primary forest had annual negative carbon *** the growing season,the total NSC concentrations of seedlings gradually decreased,whereas those of seedlings in the secondary forest increased significantly in autumn,and were mainly stored in roots for winter consumption and the following year's summer shade period,which was verified by the nursery-controlled experiment that simulated autumn enhanced light availability improved seedling survival rate and NSC *** conclusion,our results revealed the survival trade-off strategies of Quercus mongolica seedlings and highlighted the necessity of high light availability d

关键词： Carbon gain Nonstructural carbohydrate Recruitment Trade-off Biomass allocation

Purification and anti-inflammatory effect of selenium-containing protein fraction from selenium-enriched Spirulina platensis

在线全文

学校读者我要写书评

暂无评论

Food Bioscience 2022年第1期45卷 197-203页

作者： Pingyingzi Jiang Jinhao Meng Lifei Zhang Li Huang lulu wei Yunxia Bai Xiaoling Liu Shubo Li College of Light Industry and Food Engineering Guangxi UniversityNanning530004China

Spirulina platensis is an excellent carrier of Se,and thus widely used in medical fields and as well as in the food ***,there is little information about the characteristics and bioactivity of selenium-containing *** proteins(Se-SP).In this study,Se-SP with different molecular weights were isolated from selenium-enriched ***,and the bioactivities(such as antioxidant and anti-inflammatory activities)of Se-SP were ***-SP3(with a molecular weight range of 20-48 kDa)showed better free radical scavenging ability(ABTS)than the other *** addition,Se-SP3 suppressed inflammatory cytokines,in which decreased by 74% interleukin 6(IL-6),42.28% tumor necrosis factor-α(TNF-α),69.07% content of malondialdehyde(MDA),40.45% interleukin-1β(IL-1β)relative to the LPS ***,Se-SP3 decreased the nitric oxide(NO)production by 64.84% compared with the LPS group and increased the activities of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px),indicating that Se-SP3 has excellent antioxidant and anti-inflammatory activities,and could be used as a functional food ingredient or natural medicine.

关键词： Selenium Spirulina platensis protein Purification Bioactivities Inflammatory cytokines

Tumor microenvironment-activatable neuropeptide-drug conjugates enhanced tumor penetration and inhibition via multiple delivery pathways and calcium deposition

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第4期35卷 292-297页

作者： Yi Cao Xiaojiao Ge Yuanyuan wei lulu He Aiguo Wu Juan Li Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology Zhejiang International Cooperation Base of Biomedical Materials Technology and ApplicationChinese Academy of Sciences(CAS)Key Laboratory of Magnetic Materials and DevicesNingbo Cixi Institute of Biomedical EngineeringZhejiang Engineering Research Center for Biomedical MaterialsNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China University of Chinese Academy of Sciences Beijing 100049China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516000China

Peptide-drug conjugates have achieved considerable development and application as a novel strategy for targeted delivery of anticancer drugs. Bioactive peptides induced calcium deposition can irreversibly assist inhibition of tumors. However, active regulation of calcium level through signal transduction of bioactive substances has not been reported yet. In this study, novel neuropeptide-doxorubicin conjugates(NP-DOX) with lysosome-specific acid response were described for neuropeptide Y_1 receptor(Y_1R)-overexpressed triple-negative breast cancer. The delivery mechanism of NP-DOX was clarified that diverse pathways were involved, including intracellular and intercellular transport. Importantly, up-regulation of Y_1 R-mediated intracellular calcium level via second messenger inositol triphosphate was presented in NP-DOX treated MDA-MB-231 cells. In vivo antitumor efficacy demonstrated that NP-DOX showed less organ toxicity and enhanced tumor inhibition benefited from its controlled release and Y_1R-mediated calcium deposition, compared with free DOX. This bioconjugate is a proof-of-concept confirming that neuropeptide-mediated control of signaling responses in neuropeptide-drug conjugates enables great potential for further applications in tumor chemotherapy.

关键词： Neuropeptide-drug conjugate Tumor penetration Calcium deposition Tumor inhibition Triple-negative breast cancer

An aqueous ZnCl2/Fe(bpy)3Cl2 flow battery with mild electrolyte

在线全文

学校读者我要写书评

暂无评论

Frontiers of Materials Science 2020年第4期14卷 442-449页

作者： Zhipeng XIE lulu wei Shengwen ZHONG Faculty of Materials Metallurgy and Chemitry Jiangxi University of Science and TechnologyGanzhou 341000China

The kinetics of electrode reaction was investigated by cyclic voltammetry,and cyclic voltammograms show that the reversibility of the Fe(bpy)3^2+/Fe(bpy)^3+electrode reaction is better than that of the Zn/Zn^2+electrode reaction on the graphite ***,the Fe(bpy)3^2+ion diffusion in electrolyte is subject to greater resistance than that of the Zn^2+ion *** stability of the Fe(bpy)3Cl2 solution was investigated by UV-vis spectroscopy,and the performance of a mild redox flow battery employing ZnCl2 and Fe(bpy)3Cl2 in the NaCl aqueous solution with various membranes as the separator was also *** was found that the Celgard 3501 membrane cannot effectively prevent Fe(bpy)3^2+ions from leaking into anolyte,leading to the rapid failure of the flow *** the Nafion 115 membrane can be polluted by Fe(bpy)32+ions,it is not *** Nafion 115 membrane shows good selectivity,which can avoid Fe(bpy)32 ions from leakage into *** ZnCl2/Fe(bpy)3Cl2 flow battery with the Nafion 115 membrane exhibits the capacity retention of 80%after 200 cycles.

关键词： redox flow battery zinc bipyridine iron