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Comparison of ultrasound-measured properties of the common carotid artery to tobacco smoke exposure in a cohort of Indonesian patients

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World Journal of emergency Medicine 2017年第3期8卷 177-183页

作者： Allen R.yu Bima Hasjim luke e.yu Christopher Gabriel Alexander Anshus Jonathan B.Lee Michael J. Louthan esther C.Kim Katrina Lee Christina Tse Thomas Keown Shadi Lahham Maili Alvarado Steven Bunch Abdulatif Gari J.Christian Fox School of Medicine University of California Department of emergency Medicine University of California

BACKGROUND: The purpose of this study was to use point-of-care ultrasound(POCUS) to investigate the relationship between tobacco smoke exposure and the characteristics of the common carotid artery(CCA). The effect of both primary and secondary smoking on CCA properties was ***: We performed a prospective cross-sectional study across 20 primary care clinics in Bandung, West Java, Indonesia in July 2016. Point of care ultrasound was performed on a convenience sample of Indonesian patients presenting to clinic. The CCA wall stiffness and carotid intima-media thickness(CIMT) were measured during diastole and systole. These measurements were correlated with smoke exposure and cardiovascular ***: We enrolled 663 patients in the study, with 426 patients enrolled in the smoking category and 237 patients enrolled in the second-hand smoke category. There was an overall positive correlation with the measured lifestyle factors and the ultrasound-measured variables in the group of individuals who smoked. For all variables, age seemed to contribute the most out of all of the lifestyle factors for the positive changes in CIMT and CCA wall ***: Our data yielded correlations between CCA properties and cardiovascular risk, as well as between CIMT and arterial stiffness. We were also able to demonstrate an increase in thickness of the CIMT in patients who have been exposed by tobacco through the use of ultrasound. Further large scale studies comparing patients with multiple cardiac risk factors need to be performed to confi rm the utility of ultrasound fi ndings of cardiovascular disease and stroke.

关键词： Carotid artery thickness Point of care ultrasound Indonesia Intimal thickness

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An advanced 2D/3D g-C_(3)N_(4)/TiO_(2)@MnO_(2) multifunctional membrane for sunlight-driven sustainable water purification

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Nano Research 2024年第4期17卷 2368-2380页

作者： Fan yu Chunjia Luo Xiaohan Niu Min Chao Pengfei Zhang luke Yan Polymer Materials&engineering Department School of Materials Science&EngineeringChang’an UniversityXi’an 710064China Key Laboratory of Road Construction Technology and equipment MOEChang’an UniversityXi’an 710064China School of Textile Science and engineering Xi’an Polytechnic UniversityXi’an 710064China

Graphitic carbon nitride(g-C_(3)N_(4))nanosheets have attracted widespread interest in the construction of advanced separation ***,dense stacking and a single functionality have limited the membrane ***,an advanced two-/three-dimensional(2D/3D)g-C_(3)N_(4)/TiO_(2)@MnO_(2) membrane is constructed by intercalating 3D TiO_(2)@MnO_(2) nanostructures into g-C_(3)N_(4) *** 3D flower-like nanostructures broaden the transport channels of the composite *** membrane can effectively separate five oil-in-water(O/W)emulsions,with a maximum flux of 3265.67±15.01 L·m^(-2)·h^(-1)·bar^(-1) and a maximum efficiency of 99.69%±0.45%for toluene-in-water emulsion(T/W).Meanwhile,the TiO_(2)@MnO_(2) acts as an excellent electron acceptor and provides positive spatial separation of electrons–holes(e^(-)–h^(+)).The formation of 2D/3D heterojunctions allows the material with wider light absorption and smaller bandgap(2.10 eV).These photoelectric properties give the membrane good degradation of three different pollutants,with about 100%degradation for methylene blue(MB)and malachite green(MG).The photocatalytic antibacterial efficiency of the membrane is also about 100%.After cyclic experiment,the membrane maintains its original separation and photocatalytic *** remarkable multifunctional and self-cleaning properties of the g-C_(3)N_(4) based membrane represent its potential value for complex wastewater treatment.

关键词： graphitic carbon nitride(g-C_(3)N_(4))based membrane three-dimensional(3D)nanostructures self-cleaning multifunction

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effect of stress-dependent microannulus aperture on well leakage

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Journal of Rock Mechanics and Geotechnical engineering 2024年第6期16卷 1967-1976页

作者： Meng Meng luke P.Frash J.William Carey Mohamed Mehana Wenfeng Li Bailian Chen earth and environmental Sciences Los Alamos National LaboratoryLos AlamosNMUSA

Debonding at the cement-casing interface is recognized as a principal failure mechanism leading to CO_(2) leakage in *** detachment gives rise to a microannulus,which notably possesses greater permeability than undamaged cement,undermining its sealing ***,the permeability of the microannulus is regarded as a uniform value throughout the ***,fundamentally,a microannulus is one type of fracture,and its gap or aperture size is affected by the effective *** this work,we developed a unique experimental *** equipment facilitates the curing of cement inside a steel casing,the formation of a microannulus between the casing and the cement,and the investigation of the fluid flow dynamics along the microannulus under laboratory-replicated in situ *** microannulus was formed by injecting fluid from one end of the setup,and receiving similar amount of fluid on the other end signified the development of the leakage ***,strain gauges affixed to the casing’s external surface yielded key information on the microannulus’s opening and *** observed a noticeable decline in microannulus hydraulic aperture(or permeability)in relation to effective stress and an exponential equation fits their *** findings also indicate a distinct behavior when comparing liquid CO_(2) with ***,it is easier for liquid CO_(2) to create the ***,the hydraulic aperture range for this microannulus(0.7-6 mm)is considerably smaller than that created by water flow(2-17 mm).Finally,we integrated the stressdependent microannulus aperture size into the combined analysis of well mechanical integrity and well *** outcomes consistently demonstrated that when factoring in the stress-dependent aperture sizes,the leakage rates are 3e5 times compared to a fixed aperture *** traditional assumption of a constant aperture significantly underestimates fluid leakage risks.

关键词： Microannulus Leakage assessment Aperture size Triaxial experiment Carbon sequestration

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Matched pair analysis of the effect of longer hypothermic machine perfusion time on kidney transplant outcomes

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World Journal of Transplantation 2024年第3期14卷 95-101页

作者： Carlos Verdiales luke Baxter Hyun Ja Lim Gavin Beck Michael A Moser Department of Surgery University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada College of Medicine University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada Canada and Northern Ontario School of Medicine Thunder BayOntario P7B 5E1Canada Department of Community Health and epidemiology University of SaskatchewanSaskatoonSaskatchewan S7N 0W8Canada

BACKGROUND Hypothermic machine perfusion(HMP)has demonstrated benefits in terms of early kidney transplant function compared to static cold *** longer preservation times have shown detrimental effects,a previous paired study indicated that longer pump times(the second kidney in a pair)might lead to improved *** To revisit the prior paired study's somewhat unexpected results by reviewing our program's *** A total of 61 pairs of transplant recipients who received kidneys from the same donor(2012-2021)were *** were divided into two groups depending on whether they were transplanted first(K1)or second(K2).Therefore,the patients in each pair had identical donor characteristics,except for time on the *** analyses included Kaplan-Meyer analysis and paired tests,including McNemar's test,student's paired t-test,or Wilcoxon's test,as *** The two groups of recipients had similar demographics(age,body mass index,diabetes,time on dialysis,sensit-ization and retransplants).Cold ischemic times for K1 and K2 were 8.9(95%CI:7.9,9.8)and 14.7 hours(13.7,15.8)(Per rate of freedom from biopsy-proven acute rejection at 1 year(P=0.015).Delayed graft function was less common in K2,12/61(20%)than in K1,20/61(33%)(P=0.046).Finally,K2 showed a higher graft survival than K1(P=0.023).CONCLUSION Our results agree with a previous study that suggested possible advantages to longer pump *** studies should encourage further research into HMP's potential anti-inflammatory effect.

关键词： Hypothermic machine perfusion Paired kidney study early acute rejection

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g-C_(3)N_(4)/MXene@Ag多功能膜制备及其水净化性能研究

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功能材料 2024年第6期55卷 6009-6018页

作者：于帆王俊怡赵瑞琪骆春佳晁敏颜录科长安大学材料科学与工程学院西安710064

通过真空辅助组装构建g-C_(3)N_(4)/MXene@Ag(CNMA)分离膜。研究表明,银纳米粒子的引入可以增强表面润湿性并优化传质通道,复合膜最高分离通量(对水包1,2-二氯乙烷乳液)为(6812.7±106)L m^(-2)h^(-1)bar^(-1),最大效率可达99.7%。值得... 详细信息

通过真空辅助组装构建g-C_(3)N_(4)/MXene@Ag(CNMA)分离膜。研究表明,银纳米粒子的引入可以增强表面润湿性并优化传质通道,复合膜最高分离通量(对水包1,2-二氯乙烷乳液)为(6812.7±106)L m^(-2)h^(-1)bar^(-1),最大效率可达99.7%。值得注意的是,CNMA复合膜具有显著的抗污能力,在连续使用10次后仍保持稳定的分离性能。此外,MXene@Ag材料能够优化复合膜体系的能带结构,促进电子-空穴(e^(-)-h^(+))的有效空间分离,从而改善光电性能,实现对有机污染物(染料、抗生素)的高效去除,其中对亚甲基蓝染料的降解效率为98%。CNMA分离膜适用于有机污染物场景下的水环境修复,满足实际污水处理要求,具有十足的发展前景。

关键词： g-C_(3)N_(4) 多功能膜油水分离光催化水净化

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高平市汤王头村砖雕壁画墓装饰系统研究

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故宫博物院院刊 2024年第5期 114-138,143页

作者：熊天翼李路珂俞莉娜李广华杨林中清华大学建筑学院北京大学中国考古学研究中心北京大学考古文博学院故宫博物院文物保护标准化研究所山西省考古研究院

本文通过精细测绘手段对山西高平汤王头村金代砖雕壁画墓的建筑装饰进行了整体性研究。在建筑装饰系统层面,该案例与《营造法式》彩画制度具有较多共通之处。在纹样层面,该墓具有晋东南地区铺地卷成纹样的典型特征,存在一套较为完整的... 详细信息

本文通过精细测绘手段对山西高平汤王头村金代砖雕壁画墓的建筑装饰进行了整体性研究。在建筑装饰系统层面,该案例与《营造法式》彩画制度具有较多共通之处。在纹样层面,该墓具有晋东南地区铺地卷成纹样的典型特征,存在一套较为完整的图案分件系统。在整体空间层面,该墓遵循多层次“间装”原则,体现出高度程式化特征,并出现了几类少见实例做法。此外,本文对该案例建筑空间色彩进行了整体复原。

关键词：墓葬建筑建筑装饰建筑彩画建筑色彩

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Inferring the genome-wide history of grasses

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Molecular Plant 2022年第4期15卷 591-592页

作者： Matheus e.Bianconi Pascal-Antoine Christin luke T.Dunning ecology and evolutionary Biology School of BiosciencesUniversity of SheffieldWestern BankSheffield S102TNUK Department of Biology University of FribourgChemin du Musée 101700 FribourgSwitzerland

establishing the relationships among organisms is fundamental to numerous fields in biology,including systematics,evolutionary biology,and *** relationships are represented via phylogenetic trees,which depict the history of genes and capture both speciation and gene duplication *** multiple genes are analyzed simultaneously,the history of the genomes and the species that bear them can be reconstructed,as well as episodes of genetic exchanges among *** genomics revolution and analytical advancements have led to large-scale genome-wide phy-logenies resolving the history of an increasing number of taxonomic groups and revealing in some cases complex histories of ***,large groups of plants remain to be analyzed in depth.

关键词： simultaneous revealing evolutionary

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Towards disentangling the classification of freshwater fish trypanosomes

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Marine Life Science & Technology 2023年第4期5卷 551-563页

作者： Peng Zhang Jie Liu Xiao‑Ming Yin Jun‑yu Zhou Julius lukeš Zhao‑Rong Lun De-Hua Lai Guangdong Provincial Key Laboratory of Aquatic economic Animals State Key Laboratory of BiocontrolSchool of Life SciencesSun Yat-sen UniversityGuangzhou 510275China BGI Genomics BGI-ShenzhenShenzhen 518083China Institute of Parasitology Biology CentreCzech Academy of SciencesČeskéBudějovice(Budweis)37005Czech Republic Biomedical Research Centre School of ScienceEngineering and EnvironmentUniversity of SalfordSalford M54WTUK

Currently,new species of freshwater fish trypanosomes,which are economically important parasites,are being described based on subjectively selected features,i.e.,their cell morphology and the host *** have performed detailed phylogenetic and haplotype diversity analyses of all 18S rRNA genes available for freshwater fish trypanosomes,including the newly obtained sequences of Trypanosoma carassii and Trypanosoma *** on a sequence similarity of 99.5%,we divide these trypanosomes into 15 operational taxonomic units,and propose three nominal scenarios for distinguishing *** and other aquatic *** find evidences for the existence of a low number of freshwater fish trypanosomes,with *** having the widest geographic and host *** analyses support the existence of an umbrella complex composed of *** and two sister species.

关键词： Freshwaterﬁsh trypanosomes 18S rRNA Morphology Phylogeny

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HeRBICIDeS THAT INHIBIT ACeTOLACTATe SYNTHASe

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Frontiers of Agricultural Science and engineering 2022年第1期9卷 155-160页

作者： Thierry LONHIeNNe Mario Daniel GARCIA yu Shang LOW luke W.GUDDAT School of Chemistry and Molecular Bioscience The University of QueenslandQueensland 4072Australia

1 INTRODUCTION Herbicides are an essential pillar in modern agricultural *** are used to selectively reduce the growth of weeds in crops and natural *** weed mitigating chemicals date back to Roman times and include substances as simple as table salt,sulfuric acid and carbon ***,these were non-selective,required high application rates and could be toxic not only to the target weeds but to other plants and to *** first major advance in the development of tailored herbicides began in the mid 1940s with the development of the first organic growth regulators such as 2,4 dichlorophenoxyacetic acid(2,4-D)[1].The next major advance came in the 1970s with the discovery of glyphosate[2],marketed as Roundup,a herbicide that is routinely used to eradicate broad leaf weeds and grasses.

关键词： crops weed routine

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Rational design of oral drugs targeting mucosa delivery with gut organoid platforms

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Bioactive Materials 2023年第12期30卷 116-128页

作者： Tianjian Tong Yijun Qi Derrick Rollins luke D.Bussiere Debarpan Dhar Cathy L.Miller Chenxu yu Qun Wang Department of Agricultural Biosystem and engineering Iowa State UniversityAmesIAUSA Department of Chemical and Biological engineering Iowa State UniversityAmesIAUSA Department of Veterinary Microbiology and Preventive Medicine College of Veterinary MedicineIowa State UniversityAmesIAUSA Interdepartmental Microbiology Program Iowa State UniversityAmesIAUSA Department of Statistics Iowa State UniversityAmesIAUSA

effective oral drugs and vaccines require high delivery efficiency across the gastrointestinal epithelia and protection of medically effective payloads(i.e.,immunogens)against gastric *** this study,hollowed nanocarriers(NCs:silica nanospheres and gold nanocages)with poly-l-lysine(PLL)coating and mammalian orthoreovirus cell attachment proteinσ1 functionalization(NC-PLL-σ1)were explored as functional oral drug delivery vehicles(ODDVs).The transport of these ODDVs to mucosal lymphoid tissues could be facilitated by microfold cells(M-cells)mediated transcytosis(viaσ1-α2–3-linked sialic acids adherence)across gastrointestinal *** coating provided protection and slow-release of rhodamine 6 G(R6G),a model *** transport effectiveness of these ODDVs was tested on intestinal organoid monolayers in *** compared with other experimental groups,the fully functionalized ODDV system(with PLL-σ1)demonstrated two significant advantages:a significantly higher transport efficiency(198%over blank control at 48 h);and protection of payloads which led to both better transport efficiency and extended-release of payloads(61%over uncoated carriers at 48 h).In addition,it was shown that the M cell presence in intestinal organoid monolayers(modulated by Rank L stimulation)was a determining factor on the transport efficiency of the ODDVs:more M-cells(induced by higher Rank L)in the organoid monolayers led to higher transport efficiency for ODDV-delivered model payload(R6G).The fully functionalized ODDVs showed great potential as effective oral delivery vehicles for drugs and vaccines.

关键词： Oral drug delivery vehicles Organoids Biomimetic virus Sigma 1 protein Gold and silica nanoparticles

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