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Examining the intrinsic foot muscles'capacity to modulate plantar flexor gearing and ankle joint contributions to propulsion in vertical jumping

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Journal of Sport and Health Science 2023年第5期12卷 639-647,F0003页

作者： Ross smith Glen Lichtwark Dominic Farris luke Kelly School of Human Movement and Nutrition Sciences The University of QueenslandBrisbaneQLD 4072Australia Sport and Health Sciences College of Life and Environmental SciencesThe University of ExeterExeterEX12LUUnited Kingdom

Background:During human locomotion,a sufficiently stiff foot allows the ankle plantar flexors to generate large propulsive *** foot stiffness(e.g.,via a carbon plate)increases the ankle’s external moment arm in relation to the internal moment arm(i.e.,increasing gear ratio),reduces plantar flexor muscles’shortening velocity,and enhances muscle force *** contrast,when activation of the foot’s intrinsic muscles is impaired,there is a reduction in foot and ankle work and metatarsophalangeal joint *** speculated that the reduced capacity to actively control metatarsophalangeal joint stiffness may impair the gearing function of the foot at the ***:We used a tibial nerve block to examine the direct effects of the intrinsic foot muscles on ankle joint kinetics,in vivo medial gastrocnemius’musculotendinous dynamics,and ankle gear ratio on 14 participants during maximal vertical ***:Under the nerve block,the internal ankle plantar flexion moment decreased(p=0.004)alongside a reduction in external moment arm length(p=0.021)and ankle joint gear ratio(p=0.049)when compared to the non-blocked *** medial gastrocnemius muscle-tendon unit and fascicle velocity were not different between conditions,the Achilles tendon was shorter during propulsion in the nerve block condition(p<0.001).Conclusion:In addition to their known role of regulating the energetic function of the foot,our data indicate that the intrinsic foot muscles also act to optimize ankle joint torque production and leverage during the propulsion phase of vertical jumping.

关键词： Ankle biomechanics Ankle gearing Foot biomechanicsTagedEnd

Grain, pellet and wax block bait take by the house mouse (Mus musculus) and non-target species: implications for mouse eradications on coral cay islands

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Integrative Zoology 2008年第3期3卷 227-234页

作者： Jennyffer CRUZ luke K-P.LEUNG Allan LISLE Dario F.RIVERA Linton STAPLES Michelle smith School of Animal Studies University of QueenslandGattonQueenslandAustralia School of Land Crop and Food SciencesUniversity of QueenslandGattonQueenslandAustralia Animal Control Technologies SomertonVictoriaAustralia

Introduced rodents have been eradicated from large numbers of offshore islands using toxic baits;however, toxicbaits have been linked with negative impacts on non-target species. The present study assessed the bait take oftarget (house mouse, Mus musculus) and non-target (buff banded rail, Rallus philippensis) animals on Northwestand Heron Islands in the Great Barrier Reef. Three non-toxic bait formulations (wax block, pellet and grain) weretested and each was applied at 1 kg ha–1 in six treatment grids. The tracks of animals visiting the baits were identifiedusing 30 tracking stations per treatment grid. A tracking station consisted of a track-board placed in the centre of asand-pad. Mean bait take differed significantly between the formulations: birds took more grain bait than wax blockbait;mice took more wax block than grain bait. Both mice and birds were equally selective of pellet bait. Thus, thefindings indicate that wax blocks are the most suitable formulation for future baiting programs to eradicate mice onthese and other islands.

关键词： island Mus musculus non-target studies non-toxic bait rodent eradication

Exceptional points and the ring laser gyroscope

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Photonics Research 2020年第3期8卷 252-256页

作者： luke HORSTMAN NING HSU JAMES HENDRIE DAVID smith JEAN-CLAUDE DIELS School of Optical Science and Engineering University of New MexicoAlbuquerqueNew Mexico 87106USA Center for High Technology Materials University of New MexicoAlbuquerqueNew Mexico 87106USA NASA Marshall Space Flight Center Space Systems DepartmentHuntsvilleAlabama 35812USA Department of Physics and Astronomy University of New MexicoAlbuquerqueNew Mexico 87131USA

An equivalence is made between the exceptional points proposed by the field of non-Hermitian quantum mechanics and the dead band observed in laser *** sensitivity enhancement near this exceptional point is plagued by increased uncertainty due to broadening of the beat-note ***,near the dead band the gyroscope response is caused by Rabi intensity oscillations and not solely by a phase ***,a distinction is made between conservative and non-conservative coupling.

关键词： laser exceptional conservative

Age as a predictor of clinical outcomes and determinant of therapeutic measures for emergency medical services treated cardiogenic shock

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Journal of Geriatric Cardiology 2023年第1期20卷 1-10页

作者： Xiaoman Xiao Jason E Bloom Emily Andrew luke P Dawson Ziad Nehme Michael Stephenson David Anderson Himawan Fernando Samer Noaman Shelley Cox William Chan David M Kaye Karen smith Dion Stub Department of Cardiology Alfred Health55 Commercial RoadMelbourneAustralia Baker Heart and Diabetes Institute 75 Commercial RoadMelbourneAustralia Department of Cardiology Western HealthFurlong RoadSt AlbansAustralia Ambulance Victoria 31 Joseph StreetBlackburnAustralia School of Public Health and Preventive Medicine Monash University553 St Kilda RoadMelbourneAustralia Department of Paramedicine Monash UniversityMcMahons RoadFrankstonAustralia

BACKGROUND The impact of age on outcomes in cardiogenic shock(CS)is poorly described in the pre-hospital *** assessed the impact of age on outcomes of patients treated by emergency medical services(EMS).METHODS This population-based cohort study included consecutive adult patients with CS transported to hospital by *** linked patients were stratified into tertiles by age(18-63,64-77,and>77 years).Predictors of 30-day mortality were assessed through regression *** primary outcome was 30-day all-cause *** A total of 3523 patients with CS were successfully linked to state health *** average age was 68±16 years and 1398(40%)were *** patients were more likely to have comorbidities including pre-existing coronary artery disease,hypertension,dyslipidemia,diabetes mellitus,and cerebrovascular *** incidence of CS was significantly greater with increasing age(incidence rate per 100,000 person years 6.47[95%CI:6.1-6.8]in age 18-63 years,34.34[32.4-36.4]in age 64-77 years,74.87[70.6-79.3]in age>77 years,P77 years had increased risk of 30-day mortality(adjusted hazard ratio=2.26[95%CI:1.96-2.60]).Older patients were less likely to receive inpatient coronary *** Older patients with EMS-treated CS have significantly higher rates of short-term *** reduced rates of invasive interventions in older patients underscore the need for further development of systems of care to improve outcomes for this patient group.

关键词： assessed services shock

Science to support conservation action in a large river system:The Willamette River,Oregon,USA

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Water Biology and Security 2023年第4期2卷 20-35页

作者： Rebecca Flitcroft luke Whitman James White Rose Wallick Laurel Stratton Garvin Cassandra smith Robert Plotnikoff Michael Mulvey Tobias Kock Krista Jones Peter Gruendike Carolyn Gombert Guillermo Giannico Andrew Dutterer Daniel Brown Hannah Barrett Brian Bangs Robert M.Hughes U.S.D.A.Forest Service Pacific Northwest Research Station3200 SW Jefferson WayCorvallisOR97331USA Oregon Department of Fish and Wildlife 28655 OR-34CorvallisOR9733USA U.S.Geological Survey Oregon Water Science Center601 SW 2nd AveSuite 1950PortlandOR97204USA Snohomish County Department of Conservation and Natural Resources 3000 Rockefeller AvenueEverettWA98201USA Oregon Department of Environmental Quality Laboratory and Environmental Assessment Division 7202 NE Evergreen ParkwaySuite 150HillsboroOR97124USA U.S.Geological Survey Western Fisheries Research Center5501A Cook-Underwood RoadCookWashington WA 98605USA River Design Group 311 SW Jefferson AvenueCorvallisOR97333USA Bureau of Reclamation Sedimentation and River Hydraulics GroupDenver Federal CenterDenverCO80225USA Oregon State University Department of FisheriesWildlifeand Conservation SciencesNash 104CorvallisOR97331USA Oregon Watershed Enhancement Board 775 Summer Street NESalemOR97301USA U.S.Fish and Wildlife Service 911 NE 11th AvenuePortlandOR97204USA Amnisopes Institute 2895 SE GlennCorvallisOR97333USA

Management and conservation efforts that support the recovery and protection of large rivers are daunting,reflecting the complexity of the challenge and extent of effort(in terms of policy,economic investment,and spatial extent)needed to afford measurable *** large systems have generally experienced intensive development and regulation,compromising their capacity to respond to disturbances such as climate change ***,large river and basin management require insights gained from social,ecological,geophysical,and hydrological *** multidisciplinary perspective can unveil the integrated relationship between a river network's biotic community and seasonally variableenvironmental conditions that are *** rivers andtheir basins are constantly changing due to anthropogenic influences and as climate modifies patterns of temperature and *** of these factors,the state of knowledge must advance to address changing *** Willamette River,in western Oregon,USA,is a prime example of a basin that has experienced significant degradation and investment in rehabilitation in recent *** science has facilitated development of fine-scale,spatially extensive datasets and models that can generate targeted conservation and rehabilitation actions that are prioritized across the entire river *** prioritization allows investment decisions to be driven by site-specific conditions while simultaneously considering potentials for ecological ***,we review hydrologic,geomorphic,ecologic,and social conditions in the Willamette River basin through time—including pre-settlement,river development,andcontemporary periods—andoffer a futurevisionfor ***,detailed informationaboutfish populations and habitat,hydrologic conditions,geomorphology,water quality,and land use can be leveraged to make informed decisions about protection,rehabilitation,and develop

关键词： Rehabilitation Flood mitigation Hydropower Fish Multidisciplinary

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你好,我的名字是Paul smith

收藏 2014年第10期 102-108页

作者：关莹 Paul smith品牌 Design Museum London Paul smithportraits by luke Hayes

小提琴家陈美在2014年索契冬奥会上代表泰国队出战障碍滑雪赛,人们纷纷感叹这是"开了外挂"的人生,在今天,想要身份转换自如且样样成功如James Bond,很难。Paul smith便是"跨界外挂人生党"的一员,超过常人的超强能力必不可少,资本时代金... 详细信息

小提琴家陈美在2014年索契冬奥会上代表泰国队出战障碍滑雪赛,人们纷纷感叹这是"开了外挂"的人生,在今天,想要身份转换自如且样样成功如James Bond,很难。Paul smith便是"跨界外挂人生党"的一员,超过常人的超强能力必不可少,资本时代金钱和人脉至关重要,除此之外,时运不济也难以成事。展现他设计生涯的展览"你好,我的名字是Paul smith"目前正在伦敦的设计博物馆展出。展览将带领观众展开一场关于Paul smith的世界的旅行,经过精心挑选的展品除时装外还包括珠宝、书籍、艺术品和古董,将探索品牌不同阶段的设计和作品;Paul smith的个人办公室将被复制展出,音频、视频、数码照片等表现形式将展现从设计师的所思所想到时装秀后台工作等一切内容。所有这些,告诉观众这精彩纷呈的人生是如何炼成。

关键词：艺术英伦风格 Paul smith 设计师伦敦男装名字时尚界英国人英吉利人

美国临床肿瘤学会IV期非小细胞肺癌化疗的临床实践指南更新

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中国肺癌杂志 2010年第3期13卷 171-189页

作者： Christopher G. AZZOLI Sherman Baker JR Sarah TEMIN William PAO Timothy ALIFF Julie BRAHMER David H. JOHNSON Janessa L. LASKIN Gregory MASTERS Daniel MILTON luke NORDQUIST David G. PFISTER Steven PIANTADOSI Joan H. SCHILLER Reily smith Thomas J. smith John R. STRAWN David TRENT Giuseppe GIACCONE 丁燕(翻译) 南娟(翻译) 刘谦(翻译) 周清华(校对) 陈军(校对) From the Memorial Sloan-Kettering Cancer Center New York NY Virginia Commonwealth University Massey Cancer Center Richmond American Society of Clinical Oncology Alexandria Virginia Cancer Center Richmond VA Vanderbilt-Ingram Cancer Center Nashville TN Northwest Oncology & Hematology Associates Coral Springs FL Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University Baltimore National Cancer Institute Bethesda MD Helen F. Graham Cancer Center Newark DE Hematology/Oncology of Indiana PC Indianapolis IN Nebraska Cancer Specialists PC Omaha NE Samuel Oschin Comprehensive Cancer Institute Los Angeles CA University of Texas Southwestern Medical Center Dallas TX British Columbia Cancer Agency Vancouver British Columbia Canada 天津医科大学总医院天津市肺癌研究所天津市肺癌转移与肿瘤微环境重点实验室

本文旨在为IV期非小细胞肺癌患者的治疗提供更新版推荐。本文资料检索源自2002年以来公布的相关随机试验文献。此指南范围限于化疗与生物治疗。更新委员会对这些文献进行了总结并提供了推荐更新。162篇文献符合标准被纳入参考。本推荐... 详细信息

本文旨在为IV期非小细胞肺癌患者的治疗提供更新版推荐。本文资料检索源自2002年以来公布的相关随机试验文献。此指南范围限于化疗与生物治疗。更新委员会对这些文献进行了总结并提供了推荐更新。162篇文献符合标准被纳入参考。本推荐基于可改善总生存期的治疗方法。仅改善无进展生存期的治疗方法推动了对毒性及生存质量的监测。对于体力状态评分为0分或1分患者的一线治疗,可推荐以铂类为基础的细胞毒性药物的两药联用。对铂类治疗有禁忌的患者,可采用非铂类细胞毒性两药联合。对于体力状态评分为2分的患者,单一细胞毒性药物即可。对于疾病进展或经过4个周期的治疗仍对治疗无反应的患者,应停止一线细胞毒性化疗。即使在6个周期后患者对治疗仍有反应,亦应停止两药细胞毒性化疗。对于伴有明确的表皮生长因子受体(epidermal growth factor receptor,EGFR)突变的患者,可推荐一线采用吉非替尼治疗;对于EGFR突变为阴性或不明确的患者,细胞毒性化疗更佳。除具有特定临床特征的患者外,可推荐贝伐单抗与卡铂-紫杉醇联用。对于通过免疫组化证实EGFR阳性的肿瘤患者,可推荐西妥昔单抗与顺铂-长春瑞滨联用。多西紫杉醇、厄洛替尼、吉非替尼或培美曲塞被推荐作为二线治疗。对于未曾接受过厄洛替尼或吉非替尼治疗的患者,可推荐厄洛替尼作为三线治疗。现有数据不足以推荐常规三线采用细胞毒性药物。已有的证据也不足以推荐常规应用分子标记物选择化疗。

关键词：临床实践指南非小细胞肺癌选择化疗美国临床肿瘤学会细胞毒性药物表皮生长因子受体 receptor 肺癌患者