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Th. effect of fitness level on cardiac autonomic regulation, IL-6,total antioxidant capacity, and muscle damage responses to a single bout of h.gh.intensity interval training

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Journal of Sport and h.alth.Science 2018年第3期7卷 363-371页

作者： lukas Cipryan h.man Motion Diagnostic Centre and Department of h.man Movement Studies Ostrava University

Purpose:Th. aim of th.s study was to investigate th. influence of th. cardiorespiratory fitness level on th. response to h.gh.intensity interval training(h.IT)with.an individually adjusted running speed of th. same relative *** evaluation focused on acute cardiorespiratory response,postexercise cardiac autonomic modulation(h.art rate variability(h.V))and bioch.mical markers of inflammation,oxidative stress,and muscle ***:Th.rty participants were divided into 3 subgroups:well trained,moderately trained,and *** th. participants performed30 min h.IT composed of 6×2 min interval exercise with.work-to-relief ratio=1 and work intensity 100%of individual velocity at maximal oxygen consumption(VO2max).Acute cardiorespiratory variables,postexercise h.V,lactate,interleukin-6(IL-6),total antioxidant capacity(TAC),creatine kinase,and myoglobin up to 4h.after h.IT were ***:Th. differences in relatively expressed cardiorespiratory variables(h.art rate,VO2)during h.IT were at most moderate,with.th. most pronounced between-group differences in absolute VO2 *** disruption of th. postexercise h.V was th. most pronounced in untrained individuals,and th.s difference persisted 1 h.after *** h.gh.st postexercise IL-6 and TAC concentrations and th. lowest ch.nges in creatine kinase and myoglobin were revealed in well-trained ***:Th. h.gh.r fitness level was associated with.th. less pronounced postexercise cardiac autonomic ch.nges and th.ir faster restoration,even wh.n th.re were similar acute cardiorespiratory *** findings were simultaneously accompanied by th. h.gh.r postexercise IL-6 and TAC concentrations and less significant ch.nges in muscle damage bioch.mical markers in well-trained individuals.

关键词： Creatine kinase h.art rate variability Inflammation Myoglobin Total antioxidant capacity Training status

Righ.-wing and populist support for climate mitigation policies:Evidence from Poland and its carbon-intensive Silesia region

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Regional Sustainability 2022年第4期3卷 281-293页

作者： Mah.r YAZAR lukas h.RMWILLE h.vard h.ARSTAD Centre for Climate and Energy Transformation Department of GeographyUniversity of BergenBergen5020Norway Wuppertal Institute for Climate Environment and EnergyDoppersberg 19Wuppertal42103Germany

Research.on environmental beh.viour is often overlooked in literature on regime destabilization in energy *** study addresses th.t gap by focusing on socio-political and demograph.c factors sh.ping support for carbon regime destabilization policies in one of th. most carbon-intensive regions of ***-intensive industries,especially coal mining and coal-based power generation,are often concentrated in a few carbon-intensive ***,decarbonization actions will affect th.se regions particularly ***,carbon-intensive regions often exert significant political influence on th. two climate mitigation policies at th. national *** on Poland,we investigate socio-political and demograph.c factors th.t correlate with.th. approval or rejection of th. two climate mitigation policies:increasing taxes on fossil fuels such.as oil,gas,and coal and using public money to subsidize renewable energy such.as wind and solar power in Poland and its carbon-intensive Silesia *** logistic regression with.individual-level data derived from th. 2016 European Social Survey(ESS)and th. 2014 Ch.pel h.ll Expert Survey(Ch.S),we find partypolitical ideology to be an important predictor at th. national level but much.less so at th. regional ***,voting for righ.-wing party is not a divisive factor for individual support of th. two climate mitigation policies eith.r nationally or *** interestingly,populism is a strong factor in support of increasing taxes on fossil fuel in th. carbon-intensive Silesia region but is less important concerning in support of using public money to subsidize renewable energy in Poland *** results sh.w th. h.terogeneity of righ.-wing party and populism with.n th. support for th. two climate mitigation ***-demograph.c factors,especially age,gender,education level,employment status,and employment sector,h.ve even more complex and h.terogeneous components in supp

关键词： Decarbonization actions Righ.-wing party Populism Climate mitigation policies Poland Silesia

Common microscopic origin of th. ph.se transitions in Ta_(2)NiS_(5) and th. excitonic insulator candidate Ta_(2)NiSe_(5)

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npj Computational Materials 2021年第1期7卷 1919-1932页

作者： lukas Windgätter Malte Rösner Giacomo Mazza h.nnes h.bener Antoine Georges Andrew J.Millis Simone Latini Angel Rubio Max Planck Institute for th. Structure and Dynamics of Matter Luruper Chaussee 14922761 HamburgGemany Radboud University Institute for Molecules and MaterialsHeijendaalseweg 1356525 AJ NijmegenNetherlands Department of Quantum Matter Ph.sics University of GenevaQuai Ernest-Ansermet 241211 GenevaSwitzerland College de France 11 place Marcelin Berthelot75005 ParisFrance Center for Computational Quantum Ph.sics Flatiron InstituteNew YorkNY 10010USA.CPHTCNRSEcole PolytechniqueIP Paris91128 PalaiseauFrance Department of Ph.sics Columbia UniversityNew YorkNY 10027USA.Nano-Bio Spectroscopy Group Departamento de Fisica de Materiales Universidad del Pais Vasco20018 San SebastianSpain

Th. structural ph.se transition in Ta-NiSes h.s been envisioned as driven by th. formation of an excitonic insulating ***,th. role of structural and electronic instabilities on crystal symmetry breaking h.s yet to be ***,th. ph.se transition in its complementary material Ta_(2)NiS_(5)does not sh.w any experimental h.nts of an excitonic insulating *** present a microscopic investigation of th. electronic and ph.nonic effects involved in th. structural ph.se transition in Ta_(2)NiSe_(5)and Ta-Niss using extensive first-principles *** both.materials th. crystal symmetries are broken by ph.non instabilities,wh.ch.in tum lead to ch.nges in th. electronic bandstructure also observed in th. experiment.A total energy landscape analysis sh.ws no tendency towards a purely electronic instability and we find th.t a sizeable lattice distortion is needed to open a *** conclude th.t an excitonic instability is not needed to explain th. ph.se transition in both.Ta_(2)NiSe_(5)and Ta_(2)NiS_(5).

关键词： ph.se structural transitions

Cytokines and fatty liver diseases

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Liver Research 2018年第1期2卷 14-20页

作者： lukas Niederreiter h.rbert Tilg Department of Internal Medicine I GastroenterologyEndocrinology&MetabolismMedical University InnsbruckInnsbruckAustria

Cytokines are considered crucial players in inflammatory-associated disorders th.ough.ut th. *** liver diseases such.as alcoh.lic liver disease(ALD)and non-alcoh.lic fatty liver disease(NAFLD)are commonly ch.racterized by lipid accumulation and in a substantial subset of patients with.inflammation in th. *** of inflammation affects long-term outcome of liver disease including evolution of liver fibrosis,cirrh.sis and h.patocellular *** th. pro-inflammatory cytokines Interleukin(IL)-1(αandβ)and tumor necrosis factor(TNF)αplay a central role in many stages of liver diseases mediating fundamental aspects of th.se diseases including acute ph.se protein synth.sis,lipid metabolism,ch.lestasis and degree of *** key cytokines released mainly by mononuclear cells affect all liver cell types and orch.strate th. production of many oth.r mediators relevant in ch.onic liver *** cytokines also regulate crucially th. development of insulin resistance,a key component of *** th.se critical mediators of inflammation by specific antibodies,especially TNFα,h.s so far not been proven successful in alcoh.lic steatoh.patitis,a cytokine-driven *** summary,inflammatory cytokines are continuously present locally and systemically in patients with.advanced fatty liver diseases,mediating and affecting th. clinical ph.notype and many features of th.se disorders.

关键词： Alcoh.lic h.patitis(Ah. Cytokines Inflammation Interleukin(IL)-1 Alcoh.lic liver disease(ALD) Non-alcoh.lic fatty liver disease(NAFLD) Tumor necrosis factor(TNF)α

Scalable orth.gonal delay-division multiplexed OEO artificial neural network trained for TI-ADC equalization

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Ph.tonics Research 2024年第1期12卷 85-105页

作者： ANDREA ZAZZI ARKA DIPTA DAS lukas h.SSEN RENATO NEGRA JEREMY WITZENS Institute of Integrated Ph.tonics RWTH Aachen University52074 AachenGermany Ch.ir of h.gh.Frequency Electronics RWTH Aachen University52074 AachenGermany

We propose a new signaling sch.me for on-ch.p optical-electrical-optical artificial neural networks th.t utilizes orth.gonal delay-division multiplexing and pilot-tone-based self-h.modyne *** sch.me offers a more efficient scaling of th. optical power budget with.increasing network *** simulations,based on220 nm silicon-on-insulator silicon ph.tonics tech.ology,suggest th.t th. network can support 31×31 neurons,with.961 links and freely programmable weigh.s,using a single 500 m W optical comb and a signal-to-noise ratio of 21.3 d B per ***,it features a low sensitivity to temperature fluctuations,ensuring th.t it can be operated outside of a laboratory *** demonstrate th. network’s effectiveness in nonlinear equalization tasks by training it to equalize a time-interleaved analog-to-digital converter(ADC)arch.tecture,ach.eving an effective number of bits over 4 over th. entire 75 Gh. ADC *** anticipate th.t th.s network arch.tecture will enable broadband and low latency nonlinear signal processing in practical settings such.as ultra-broadband data converters and real-time control systems.

关键词： network delay artificial

Measurement and Modeling for Magnetic Properties of Amorph.us Alloy Material

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Measurement and Modeling for Magnetic Properties of Amorphou...

作者： lukas Adrian Karim 厦门理工学院

学位级别：硕士

非晶态金属也称为金属玻璃或玻璃金属,是一种固体金属材料,通常是合金,具有无序的原子尺度结构。大多数金属在固态状态下都是结晶的,这意味着它们有高度有序的原子排列。非晶态合金目前最重要的应用是在工频和一些高频变压器、高效率、... 详细信息

非晶态金属也称为金属玻璃或玻璃金属,是一种固体金属材料,通常是合金,具有无序的原子尺度结构。大多数金属在固态状态下都是结晶的,这意味着它们有高度有序的原子排列。非晶态合金目前最重要的应用是在工频和一些高频变压器、高效率、低磁化损耗的变压器中。非晶态合金材料因其技术应用前景广阔而受到人们的关注。本文采用二维单片测试仪和数据采集装置,测量了一维交变和二维旋转磁场中磁通密度B与磁场强度h.关系。提出了一种测量非晶合金材料中磁通量和磁场强度分量的方法。本文在50赫兹频率的不同外加磁场激励下,对非晶合金样品的B和h.行了测量。通过对测量结果的对比分析发现:在低通量密度(0.35 T)下的测量中,Bx-h.和Byh.磁滞回线的形状几乎相同,在增加励磁电流后,两个方向的磁滞行为发生了变化。在测量磁通密度达到0.88 T时,这种现象更加明显,直到在y方向的磁通密度达到1.85T和X方向1.73 T,材料达到磁饱和值。本文采用Jiles-Ath.rton磁滞模型模拟了非晶态合金的磁滞特性。主要工作涉及用交变磁场模拟磁滞特性并与交变磁场测量B-h.果进行对比。仿真结果表明,JilesAth.rton模型具有足够的精度,可以模拟该材料的一维磁滞特性。

关键词：非晶合金材料二维磁性磁通密度磁场 B-h.量和磁滞回线

Numerical study of novel OME_(1-6) combustion mech.nism and spray combustion at ch.nged ambient environments

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Frontiers in Energy 2024年第4期18卷 483-505页

作者： Frederik WIESMANN Zeyan QIU Dong h.N lukas STRAUβ Sebastian RIEβ Mich.el WENSING Th.mas LAUER Institute of Powertrains and Automotive Tech.ology TU Wien1060 ViennaAustria Key Laboratory for Power Mach.nery and Engineering of Ministry of Education Shanghai Jiao Tong UniversityShanghai 200240China Professorsh.p for Fluid Systems Tech.ology Friedrich-AlexanderUniversität Erlangen-Nürnberg91058 ErlangenGermany

For a climate-neutral future mobility,th. socalled e-fuels can play an essential ***,oxygenated e-fuels containing oxygen in th.ir ch.mical formula h.ve th. additional potential to burn with.significantly lower soot *** particular,polyoxymeth.lene dimeth.l eth.rs or oxymeth.lene eth.rs(PODEs or OMEs)do not contain carbon-carbon bonds,proh.biting th. production of soot precursors like acetylene(C_(2)h.(2)).Th.se properties make OMEs a h.gh.y interesting candidate for future climate-neutral compression-ignition ***,to fully leverage th.ir potential,th. auto-ignition process,flame propagation,and mixing regimes of th. combustion need to be *** ach.eve th.s,efficient oxidation mech.nisms suitable for computational fluid dynamics(CFD)calculations must be developed and *** present work aims to h.gh.igh. th. improvements made by developing an adapted oxidation mech.nism for OME1-6 and introducing it into a validated spray combustion CFD model for *** simulations were conducted for single-and multi-injection patterns,ch.nging ambient temperatures,and oxygen *** results were validated against h.gh.pressure and h.gh.temperature constantpressure ch.mber ****-ch.miluminescence measurements accomplish.d th. ch.racterization of th. auto-ignition *** experiments and simulations were conducted for two different *** improvements concerning th. prediction of th. ignition delay time were accomplish.d wh.le also retaining an excellent agreement for th. flame lift-off *** spatial zones of h.gh.temperature reaction activity were also affected by th. adaption of th. reaction *** sh.wed a greater tendency to form Oh.(*) radicals with.n th. center of th. spray in accordance with.th. experiments.

关键词： oxygenated fuels reaction kinetics oxidation mech.nisms computational fluid dynamics(CFD) oxymeth.lene eth.rs(OME) e-fuels multiinjection spray-combustion

Ach.eving exceptional wear resistance in a crack-free h.gh.carbon tool steel fabricated by laser powder bed fusion with.ut pre-h.ating

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Journal of Materials Science & Tech.ology 2023年第25期156卷 1-19页

作者： Konrad Kosiba Daniel Wolf Matth.as Bönisch.Kai Neufeld Ruben h.h.e Tobias Gustmann Jozef Bednarčík h.ngyu Ch.n Xiaoliang h.n Volker h.ffmann lukas Beyer Uta Küh. Sergio Scudino Lars Giebeler Julia K.h.fenbach Leibniz Institute for Solid State and Materials Research.(IFW) Dresden E.V. Helmholtzstr. 20Dresden 01069Germany Department of Materials Engineering KU LeuvenKasteelpark Arenberg 44bus 2450Leuven 3001Belgium Department of Condensed Matter Ph.sics Institute of PhysicsP.J. Safarik University in KosicePark Angelinum 9Kosice 04154Slovakia Institute of Experimental Ph.sics Slovak Academy of ScienceWatsonova 47Kosice 040 01Slovakia Key Laboratory of Impact and Safety Engineering of Ministry of Education of Ch.na Ningbo UniversityNingbo 315211China TU Bergakademie Freiberg Institute of Materials ScienceGustav-Zeuner-Str. 5Freiberg 09599Germany

Laser powder bed fusion(LPBF)for th. fabrication of dense components used for tooling applications,is h.gh.y *** stresses,wh.ch.evolve in th. additively manufactured part,are inh.rent to LPBF *** additional stress contribution in h.gh.carbon steels arises from th. austenite-to-martensite ph.se transformation,wh.ch.may eventually lead to cracking or even *** an alternative to pre-h.ating th. base plate,wh.ch.is not striven by industry,lowering th. martensite content wh.ch.forms in th. part,is essential for th. fabrication of dense parts by LPBF of h.gh.carbon tool steels wh.ch.are th.n adapted to *** th.s study,a successful strategy demonstrates th. processing of th. Fe85Cr4Mo1V1W8C1(wt%)h.gh.carbon steel by LPBF into dense parts(99.8%).Th. h.erarch.cal microstructure consists of austenitic and martensitic grains separated by elemental segregations in wh.ch.nanoscopic carbide particles form a network.A h.gh.density of microsegregation was observed at th. molten pool boundary ultimately forming a *** LPBF-fabricated steel sh.ws a yield strength.ultimate compressive stress,and total strain of 1210 MPa,3556 MPa,and 27.4%,*** mech.nical and wear performance is rated against th. industrially employed and h.gh.y wear-resistant 1.2379 tool steel taken as th. *** its lower macro-h.rdness,th. LPBF steel(58.6 h.C,0.0061 mm^(3) Nm^(-1))sh.ws a h.gh.r wear resistance th.n th. reference steel(62.6 h.C,0.0078 mm^(3) Nm^(-1)).Th.s beh.vior results from th. wear-induced formation of martensite in a microscale th.ck layer directly at th. worn surface,as it was proven via h.gh.energy X-ray diffraction mapping.

关键词： Additive manufacturing Laser powder bed fusion Steel Wear TRIP

Croh.'s disease-related'gastrocnemius myalgia syndrome'successfully treated with.infliximab:A case report

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World Journal of Gastroenterology 2022年第7期28卷 755-762页

作者： Julien Cath.rine h.zim Kadh.m Frédéric Lambot Claire Liefferinckx Virginie Meurant lukas Otero Sanch.z Institute for Medical Immunology UniversitéLibre de BruxellesGosselies 6041Belgium Department of Internal Medicine C.U.B.Hôpital ErasmeBrussels 1070Belgium NeuroMyopath.logy Unit(Anatomic Path.logy Service)and Reference Center for Neuromuscular Path.logy CHU BrugmannUniversitéLibre de BruxellesBrussels 1020Belgium Department of Internal Medicine Centre Hospitalier Universitaire TivoliLa Louvière 7100Belgium Department of Gastroenterology Hepatopancreatology and Digestive OncologyC.U.B.Hôpital ErasmeBrussels 1070Belgium Laboratory of Experimental Gastroenterology UniversitéLibre de BruxellesBrussels 1070Belgium Department of Emergency Medicine Centre Hospitalier Universitaire TivoliLa Louvière 7100Belgium

BACKGROUND Extra-intestinal manifestations in inflammatory bowel diseases(IBD)are frequent and involve virtually all ***,th. clinical ch.racteristics and course of inflammatory myopath.es in IBD remain poorly described and mostly related to orbital ***,alternative th.rapeutic strategies in non-responder patients to corticosteroid th.rapy must still be *** SUMMARY A 33-year-old woman with.a h.story of unclassified colitis presented with.acute bilateral calf *** admission,h.r clinical and biological examinations were ***,magnetic resonance imaging sh.wed bilateral inflammatory ch.nges in gastrocnemius muscles suggestive of *** biopsy confirmed th. diagnosis of myositis and demonstrated an inflammatory infiltrate mainly located in th. perimysial compartment including lymph.-plasmocytic cells with.th. formation of several granulomatous structures wh.le th. endomysium was relatively *** combined clinical,biological and h.stomyopath.logical findings were concordant with.th. diagnosis of‘gastrocnemius myalgia syndrome’(GMS),a rare disorder associated with.Croh.’s disease(CD).Ileocolonoscopy confirmed CD diagnosis and systemic corticosteroids(CS)th.rapy was started,resulting in a rapid clinical *** CS tapering,h.wever,sh. experienced a relapse of GMS togeth.r with.a severe active *** was started and allowed a sustained remission of both.conditions at th. latest follow-up(20 mo).CONCLUSION Th. GMS represent a rare CD-associated inflammatory myopath. for wh.ch.anti-tumour necrosis factor-αth.rapy migh. be considered as an effective th.rapeutic option.

关键词： Croh.’s disease Extra-intestinal manifestation Gastrocnemius myalgia syndrome Granulomatous myositis Anti-tumour necrosis factor-αth.rapy Case report