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Cyberbullying Sexism Harassment Identification by Metaheurustics-Tuned eXtreme Gradient Boosting

Computers, Materials & Continua 2024年第9期80卷 4997-5027页

作者： Milos Dobrojevic luka jovanovic Lepa Babic Miroslav Cajic Tamara Zivkovic Miodrag Zivkovic Suresh Muthusamy Milos Antonijevic Nebojsa Bacanin Technical Faculty Singidunum UniversityBelgrade11000Serbia Informatics and Computing Singidunum UniversityBelgrade11000Serbia Business Economics Singidunum UniversityBelgrade11000Serbia Computing and Informatics Sinergija UniversityBijeljina76300Bosnia and Herzegovina Department for Information Systems and Technologies University“Union Nikola Tesla”Cara DusanaBelgrade11080Serbia Department for Computer Science and Informatics School of Electrical EngineeringUniversity of BelgradeBelgrade11000Serbia Department of Electrical and Electronics Engineering Kongu Engineering College(Autonomous)PerunduraiErode638060India Department of Mathematics Saveetha School of Engineering(Deemed to be University)SIMATS ThandalamChennai602105India MEU Research Unit Middle East UniversityAmman11831Jordan

Cyberbullying is a form of harassment or bullying that takes place online or through digital devices like smartphones,computers,or *** can occur through various channels,such as social media,text messages,online forums,or gaming *** involves using technology to intentionally harm,harass,or intimidate others and may take different forms,including exclusion,doxing,impersonation,harassment,and ***,due to the rapid growth of malicious internet users,this social phenomenon is becoming more frequent,and there is a huge need to address this ***,the main goal of the research proposed in this manuscript is to tackle this emerging challenge.A dataset of sexist harassment on Twitter,containing tweets about the harassment of people on a sexual basis,for natural language processing(NLP),is used for this *** algorithms are used to transform the text into a meaningful representation of numbers for machine learning(ML)input:Term frequency inverse document frequency(TF-IDF)and Bidirectional encoder representations from transformers(BERT).The well-known eXtreme gradient boosting(XGBoost)ML model is employed to classify whether certain tweets fall into the category of sexual-based harassment or ***,with the goal of reaching better performance,several XGBoost models were devised conducting hyperparameter tuning by *** this purpose,the recently emerging Coyote optimization algorithm(COA)was modified and adjusted to optimize the XGBoost ***,other cutting-edge metaheuristics approach for this challenge were also implemented,and rigid comparative analysis of the captured classification metrics(accuracy,Cohen kappa score,precision,recall,and F1-score)was ***,the best-generated model was interpreted by Shapley additive explanations(SHAP),and useful insights were gained about the behavioral patterns of people who perform social harassment.

关键词： Coyote optimization algorithm NLP TF-IDF BERT XGBoost online harassment and cyberbullying metaheuristics

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Rock Mass Quality Rating Based on the Multi-Criteria Grey Metric Space

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 2635-2664页

作者： Miloš Gligoric Zoran Gligoric Saša jovanovic Suzana Lutovac Dragan Pamucar Ivan Jankovic Faculty of Mining and Geology University of BelgradeBelgrade11000Serbia Faculty of Technical Sciences University of PrištinaKosovska Mitrovica38220Serbia Department of Operations Research and Statistics Faculty of Organizational SciencesUniversity of BelgradeBelgrade11000Serbia College of Engineering Yuan Ze UniversityTaoyuan City320315TaiwanChina

Assessment of rock mass quality significantly impacts the design and construction of underground and open-pit mines from the point of stability and *** study develops the novel Gromov-Hausdorff distance for rock quality(GHDQR)methodology for rock mass quality rating based on multi-criteria grey metric *** usually presents the quality of surrounding rock by classes(metric spaces)with specified properties and adequate interval-grey *** the distance between surrounding rock sample characteristics and existing classes represents the core of this *** Gromov-Hausdorff distance is an especially useful discriminant function,i.e.,a classifier to calculate these distances,and assess the quality of the surrounding *** efficiency of the developed methodology is analyzed using the Mean Absolute Percentage Error(MAPE)*** existing methods,such as the Gaussian cloud method,Discriminant method,Mutation series method,Artificial neural network(ANN),Support vector machine(SVM),Grey wolf optimizer and Support vector classification method(GWO-SVC)and Rock mass rating method(RMR)are used for comparison with the proposed GHDQR *** share of the highly accurate category of 85.71%clearly indicates compliance with actual values obtained by the compared *** results of comparisons showed that the model enables objective,efficient,and reliable assessment of rock mass quality.

关键词： Rock mass rating multi-criteria class metric space interval-grey numbers

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Prolonged intermittent theta burst stimulation restores the balance between A_(2A)R-and A_(1)R-mediated adenosine signaling in the 6-hydroxidopamine model of Parkinson's disease

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Neural Regeneration Research 2025年第7期20卷 2053-2067页

作者： Milica Zeljkovic jovanovic Jelena Stanojevic Ivana Stevanovic Milica Ninkovic Tihomir V.Ilic Nadezda Nedeljkovic Milorad Dragic Laboratory for Neurobiology Department of General Physiology and BiophysicsFaculty of BiologyUniversity of BelgradeBelgradeSerbia Medical Faculty of Military Medical Academy University of DefenceBelgradeSerbia

An imbalance in adenosine-mediated signaling,particularly the increased A_(2A)R-mediated signaling,plays a role in the pathogenesis of Parkinson's *** therapeutic approaches fail to alter disease progression,demonstrating the need for novel approaches in *** transcranial magnetic stimulation is a non-invasive approach that has been shown to improve motor and non-motor symptoms of Parkinson's ***,the underlying mechanisms of the beneficial effects of repetitive transcranial magnetic stimulation remain *** purpose of this study is to investigate the extent to which the beneficial effects of prolonged intermittent theta burst stimulation in the 6-hydroxydopamine model of experimental parkinsonism are based on modulation of adenosine-mediated *** with unilateral 6-hydroxydopamine lesions underwent intermittent theta burst stimulation for 3 weeks and were tested for motor skills using the Rotarod ***,quantitative reverse transcription polymerase chain reaction,immunohistochemistry,and biochemical analysis of components of adenosine-mediated signaling were performed on the synaptosomal fraction of the lesioned caudate *** intermittent theta burst stimulation improved motor symptoms in 6-hydroxydopamine-lesioned animals.A 6-hydroxydopamine lesion resulted in progressive loss of dopaminergic neurons in the caudate *** with intermittent theta burst stimulation began 7 days after the lesion,coinciding with the onset of motor *** treatment with prolonged intermittent theta burst stimulation,complete motor recovery was *** improvement was accompanied by downregulation of the e N/CD73-A_(2A)R pathway and a return to physiological levels of A_(1)R-adenosine deaminase 1 after 3 weeks of intermittent theta burst *** results demonstrated that 6-hydroxydopamine-induced degeneration reduced the expression of A_(1)R and elevated the expression of A_(2A)***

关键词： A_(1)R A_(2A)R adenosine receptors adenosine ecto-5′-nucleotidase intermittent theta burst stimulation non-invasive brain stimulation Parkinson's disease purinergic signalling

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Primary pancreatic lymphoma:A case report and review of literature

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World Journal of Clinical Oncology 2024年第11期15卷 1444-1453页

作者： Marko M Stojanovic Vesna Brzacki Goran Marjanovic Milica Nestorovic Jelena Zivadinovic Miljan Krstic Marko Gmijovic Ilija Golubovic Svetlana jovanovic Miroslav P Stojanovic Katarina Terzic Department of Gastroenterology and Hepatology Clinic University Clinical Center NisMedical Faculty University of NisNis 18000Serbia Immunology Medical Faculty University of NisNis 18000Serbia Clinic for Digestive Surgery University Clinical CenterMedical Faculty University of NisNis 18000Serbia Clinic of Aneasthesiology and Intensive Therapy University Clinical Center NisUniversity of NisNis 18000Serbia Department of Pathology Medical Faculty University of NisNis 18000Serbia

BACKGROUND Primary pancreatic lymphoma(PPL)is a rare tumor that mimics pancreatic adenocarcinoma,leading to diagnostic and therapeutic *** accounts for 0.2%of all pancreatic tumors and is typically treated with ***,the long-term survival rates for PPL with chemotherapy and radiotherapy alone are *** to the improvements in pancreatic surgery,there is a need to reevaluate the treatment strategies for *** SUMMARY A 62-year-old male presented to our clinic.A biopsy was unsuccessful,and the imaging was suggestive of pancreatic ***,subtotal splenopancreatectomy was performed and histopathology was *** was then diagnosed with primary pancreatic diffuse large B-cell *** received adjuvant chemotherapy and ***,the patient is alive with no evidence of disease 36 months after *** The potential role of surgery in the treatment of PPL should be emphasized and added in the management protocol of early stage lymphoma.

关键词： Lymphoma Primary Pancreas Treatment Strategy Surgery Case report

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Purinergic Modulation of Activity in the Developing Auditory Pathway

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Neuroscience Bulletin 2020年第11期36卷 1285-1298页

作者： Sasa jovanovic Ivan Milenkovic School of Medicine and Health Sciences Carl von Ossietzky University Oldenburg26129 OldenburgGermany

Purinergic P2 receptors,activated by endogenous ATP,are prominently expressed on neuronal and nonneuronal cells during development of the auditory periphery and central auditory *** the mature cochlea,extracellular ATP contributes to ion homeostasis,and has a protective function against noise ***,we focus on the modulation of activity by extracellular ATP during early postnatal development of the lower auditory *** mammals,spontaneous patterned activity is conveyed along afferent auditory pathways before the onset of acoustically evoked signal *** this critical developmental period,inner hair cells fire bursts of action potentials that are believed to provide a developmental code for synaptic maturation and refinement of auditory circuits,thereby establishing a precise tonotopic *** ATP-release triggers such patterned activity by raising the extracellular K+concentration and contributes to firing by increasing the excitability of auditory nerve fibers,spiral ganglion neurons,and specific neuron types within the auditory brainstem,through the activation of diverse P2 *** review recent studies that provide new models on the contribution of purinergic signaling to early development of the afferent auditory ***,we discuss potential future directions of purinergic research in the auditory system.

关键词： Purinergic signaling Auditory system Development Cochlea Spiral ganglion Auditory brainstem

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High-Resolution Spectra of the ^10B^18O and ^11B^18O： Rotational Analysis of the B-X Bands

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Chinese Physics Letters 2005年第4期22卷 857-860页

作者： V.Bojovic A.Antic-jovanovic M.Kuzmanovic FacultyofPhysicalChemistry UniversityofBelgradePOBox13711001BelgradeSerbiaandMontenegro

Emission spectra of 10B18O and 11B18O isotopomers in the 230--330nm region have been investigated by means of conventional high-resolution spectroscopy. The molecules were produced in a low-pressure arc by discharging 8 Torr of mixture containing argon and oxygen 18 in the ratio of 4:1 and the spectra have been recorded using Ebert-type spectrograph. The boron needed to produce BO has been present in the system as amorphous powder with natural abundance of 10B and 11B. Rotational analysis of the 0, 0 and 0, 1 bands has been performed and spectroscopic constants have been extracted. The results have allowed first determination of the equilibrium rotational constants Be and De for both isotope species 10B18O and 11B18O in their lower electronic state. Assuming a linear dependence of Be on (v +1/2), the value of equilibrium distance re in the lower state has been derived.

关键词：高分辨率光谱 ^10B^18O ^11B^18O 分子物理学旋转性质同位素

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An Application of the Shark Skin Denticle Geometry for Windbreak Fence Design and Fabrication

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Journal of Bionic Engineering 2017年第3期14卷 579-587页

作者： Ivana Bajsanski Vesna Stojakovic Bojan Tepavcevic Marko jovanovic Dejan Mitov Department of Architecture Faculty of Technical Sciences University of Novi Sad Trg Dositeja Obradoviea 6 21000 Novi Sad Serbia

Windbreak fences in open and urban areas can be used to effectively reduce the wind velocity. In this paper we examine how the geometrical shape of the windbreak fence can optimally mitigate wind velocity. We propose an approach for windbreak fence design based on a bionic parametric model of the shark skin denticle geometry, which improves the reduction of the wind velocity around and behind the windbreak fences. The generative model was used to estimate improvements by variations in the parameters of the fence panel＇s geometrical shape, inspired by shark skin denticles. The results of the Computational Fluid Dynamics （CFD） analysis indicates that the fence surface inspired by shark skin performs much better than both flat and cor- rugated surfaces. Taking into account the complex geometry of the surface inspired by shark skin denticles, we propose a fab- rication process using an expanded polystyrene foam （EPS） material, created using an industrial robot arm with a hot-wire tool. Creating EPS moulds for the shark skin denticle panels allows for a richer variety material to be used in the final design, leading both to higher efficiency and a more attractive design.

关键词： bioinspiration shark skin denticle windbreak fence design generative models CFD

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Metabolic syndrome attenuates ulcerative colitis: Correlation with interleukin-10 and galectin-3 expression

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World Journal of Gastroenterology 2019年第43期25卷 6465-6482页

作者： Marina jovanovic Bojana Simovic Markovic Nevena Gajovic Milena Jurisevic Aleksandar Djukic Ivan jovanovic Nebojsa Arsenijevic Aleksandra Lukic Natasa Zdravkovic Department of Internal Medicine Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Center for Molecular Medicine and Stem Cell Research Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Department of Pharmacy Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Department of Pathophysiology Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia Department of Dentistry Faculty of Medical SciencesUniversity of KragujevacKragujevac 34000Serbia

BACKGROUND Ulcerative colitis(UC)is a chronic disease characterized by inflammation of intestinal epithelium,primarily of the *** increasing prevalence of metabolic syndrome(MetS)in patients with UC has been documented ***,there is no evidence that MetS alters the course of the *** To test the influence of the MetS on the severity of UC and the local and systemic immune *** Eighty nine patients with de novo histologically confirmed UC were divided in two groups,according to ATP III criteria:Group without MetS(no MetS)and group with *** Clinically and histologically milder disease with higher serum level of immunosuppressive cytokine interleukin-10(IL-10)and fecal content of Galectin-3(Gal-3)was observed in subjects with UC and MetS,compared to subjects suffering from UC *** was accompanied with predomination of IL-10 over pro-inflammatory cytokines tumor necrosis factorα(TNF-α),interleukin-6(IL-6),and interleukin-17(IL-17)in the sera as well as Gal-3 over TNF-αand IL-17 in feces of UC patients with ***,the patients with both conditions(UC and MetS)had higher percentage of IL-10 producing and Gal-3 expressing innate and acquired immune cells in lamina *** Local dominance of Gal-3 and IL-10 over pro-inflammatory mediators in patients with MetS may present a mechanism for limiting the inflammatory process and subsequent tissue damage in UC.

关键词： Ulcerative colitis Metabolic syndrome Galectin-3 Inflammation Interleukin-10 Systemic immune response

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Seasonal dynamics of foliar antioxidative enzymes and total anthocyanins in natural populations of Iris pumila L.

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Journal of Plant Ecology 2010年第1期3卷 59-69页

作者： Ana Vuleta Sanja Manitasevic jovanovic Darka Seslija Branka Tucic Department of Evolutionary Biology Sinisa Stankovic Institute for Biological ResearchBelgradeSerbia Department of Biochemistry Sinisa Stankovic Institute for Biological ResearchBelgradeSerbia

Aims Plants in their natural habitats frequently cope with a multitude of abiotic stresses,such as high light intensity,extreme temperatures and water deficit,which often co-occur during periods of drought,especially in semi-arid and arid *** of plants to stressful environmental conditions usually induce overproduction of reactive oxygen species(ROS)that,as highly toxic derivatives of O_(2),can assault all cell macromolecules,leading to the disruption of cellular homeostasis and,consequently,the uncoupling of major metabolic processes,the photosynthesis and *** order to minimize ROS-mediated cellular damage,plants have evolved highly efficient antioxidative defense systems that include both enzymatic and non-enzymatic *** abiotic stress can also operate as a strong evolutionary force that shapes adaptations in natural plant populations,the aim of this study was to examine the seasonal variation patterns of two distinct antioxidative systems,ROS-scavenging enzymes and anthocyanin pigments,in the leaf tissue of a steppe plant,Iris pumila,as expressed under contrasting light conditions that the species regularly experiences in the *** We selected two natural populations of *** inhabiting the alternative radiation environments in the Deliblato Sands,a sunexposed dune site and a woodland *** specific activity of three antioxidative enzymes,superoxide dismutase(SOD),catalase(CAT)and peroxidase(POD)and the content of total anthocyanins were examined in leaves of *** plants collected from each of the 31 Iris clones(17 in the exposed population and 14 in the shaded population)once during each of the three seasons,spring,summer and autumn in ***,a fully expanded leaf was cut from each clonal plant between 15:00 and 16:00 h,immediately frozen in liquid nitrogen and stored at-70℃until *** Findings Generally,all three antioxidative enzymes were up-regulated in summer-harvested

关键词： SOD CAT POD anthocyanins seasonal variation

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The effects of selection for early and late reproduction on metabolite pools in Acanthoscelides obtectus Say

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Insect Science 2012年第3期19卷 303-314页

作者： Jelica Lazarevie Nikola Tucic Darka Se.slija jovanovic Josef Vecera Dalibor Kodrik Institute for Biological Research Belgrade Biological faculty University of Belgrade Belgrade Serbia Institute of Entomology Biology Centre Czech Academy of Sciences Ceske Budejovice Faculty of Sciences University of South Bohemia Ceske Budejovice Czech Republic

The present study was aimed at revealing the responses of metabolite pools to selection for alternative reproductive schedules in the seed beetle, Acanthoscelides obtectus Say （Coleoptera： Chrysomelidae： Bruchinae）. The levels of metabolites （free sugars, glycogen, lipids, soluble and hydrophobic proteins） that were determined in virgin females and males at three ages from adult eclosion onwards were compared among the base population （B） and two derived lines that were selected for either early （Y） or late （O） reproduction. The results showed differences in the accumulation of metabolites during pre-adult development, as well as in the pattern of their changes during adult ageing, Generally, in comparison to the B population, the short-lived beetles from the Y line showed increased protein content and reduced carbohydrate and lipid content, whereas the opposite was true for the long-lived beetles from the O line. Females from the O line exhibited slower utilization of energy reserves and a slower increase in protein contents than females from the Y line. Females contained higher levels of free sugars, glycogen and hydrophobic proteins and lower levels of lipids and soluble proteins than males, although the sexual dimorphism was not evenly expressed among lines. Age-specific changes in metabolite contents were slower in females than males. Our findings suggest that trade-offs among capital resources are a physiological basis of early/late fitness trade-offs and point to a conservation of resources that can be used for somatic maintenance.

关键词： ageing energy resources laboratory evolution proteins seed beetle,trade-off

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