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快速响应的LaF3基质氧传感器

电子与仪表 1995年第1期 33-34页

作者： luka.,JP 刘烨

利用ＬａＦ３单晶（氟化物离子导体）和酞菁铅作传感器材料，制作了在室温下工作的固体电解质氧化感器，传感器的电动势稳定地随氧分压的改变而变化，其特征是氧分子的双电子还原反应，而且传感器的９０％响应时间在３０℃时为３０秒。

关键词：氧传感器敏感电极传感器氟化物离子导体金属

Patient Satisfaction in Croatian Nationwide Mammography Screening Program

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International Journal of Clinical Medicine 2017年第3期8卷 159-166页

作者： Brnic Zoran Kasnik Kristina Kasnik Katarina Brnic Vedran Borojevic Nikola Ljubesic luka Schmidt Sasa Krpan Tomislav Clinical Hospital Center“Sisters of Mercy” ZagrebCroatia

Mammographic screening programs are essential in timely detection and effective treatment of breast cancer. Since 2006, Croatia implemented a national MSP which asks for a regular biannual mammography for all women 50 - 69 years of age. First-visit screening attendance in the country is estimated at 58.3% with the trend of gradually decreasing re-attendance rates. Since patient satisfaction with the screening procedure may influence subsequent adherence, this study aimed to assess patient satisfaction in order to predict and improve patient re-attendance rate, a first-time effort of such kind in Croatia. 201 random patients undergoing mammography screening procedure at four facilities in Croatia were asked to complete an anonymous questionnaire which specifically evaluated the following aspects of patient experience: patient attitude, facility surroundings, staff attitude and pre-examination information transfer, associated physical pain, psychological discomfort, and finally overall patient impressions and satisfaction. The majority of our examinees expressed high satisfaction with MSP and an intention to re-screen;patient attitude, facility environment and staff attitude were deemed overly positive, whereas the majority of patients estimated the physical and psychological pain associated tolerable. These results suggest that patient satisfaction is not a critical factor influencing future adherence rate in MSP, and other components of the program should be evaluated and improved.

关键词： Croatian Mammography Screening Program Patient Satisfaction

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尾砂水泥胶结充填料试验报告

中国矿山工程 1976年第Z1期 51-64+23页

作者： W.S.Weaver luka 采矿科加拿大魁北克省芒特雷尔Lafarge水泥有限公司

加拿大两个基础工业——建筑与采矿——合作发展了“水泥尾砂胶结体”,本文回顾了实验室试验的成果。加拿大水泥有限公司与两家采矿公司紧密配合下,于1961年在魁北克省的Hull开始进行研究,采用了特殊的技术以克服试验中的困难。对砂浆... 详细信息

加拿大两个基础工业——建筑与采矿——合作发展了“水泥尾砂胶结体”,本文回顾了实验室试验的成果。加拿大水泥有限公司与两家采矿公司紧密配合下,于1961年在魁北克省的Hull开始进行研究,采用了特殊的技术以克服试验中的困难。对砂浆浓度、水泥含量、尾砂粒度、白榴火山灰、掺和剂及其它变数等与水泥尾砂胶结体的影响关系均进行了研究,针对用作隔墙、铺地板、一般充填法采场的充填和深孔爆破采场的充填等都进行了研究。试验浇成6×12吋的园柱体,2×2×4呎的箱子及采用8呎长的模型采场。 1966年在安大略省的Belleville建成了更先进的大规模试验厂,1967～1970年获得国家研究委员会的津贴并进行一些特殊的试验项目,包括6吋园柱体的三向轴压力试验。对尾砂的正式研究计划现已完成。本文总结了八年来上千次试验的研究结果。

关键词：尾砂水泥矿山充填料砂浆浓度

六倍体小黑麦中Glu—D1基因从1D染色体到1A染色体的转移

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国外作物育种 1995年第2期14卷 18-21页

作者： luka.,AJ 雷波

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

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Cellular & Molecular Immunology 2022年第2期19卷 234-244页

作者： Yeonsu Kim Xiaoyan Zheng Kathrin Eschke M.Zeeshan Chaudhry Federico Bertoglio Adriana Tomić Astrid Krmpotić Markus Hoffmann Yotam Bar-On Julia Boehme Dunja Bruder Thomas Ebensen Linda Brunotte Stephan Ludwig Martin Messerle Carlos Guzman Ofer Mandelboim Michael Hust Stefan Pöhlmann Stipan Jonjić lukaČičin-Šain Department of Viral Immunology Helmholtz Centre for Infection Research(HZI)BraunschweigGermany Department of Biotechnology Institut für BiochemieBiotechnologie und BioinformatikTechnischen Universität BraunschweigBraunschweigGermany Oxford Vaccine Group University of OxfordOxfordUK Center for Proteomics University of RijekaFaculty of MedicineRijekaCroatia Infection Biology Unit German Primate CenterGöttingenGermany Faculty of Biology and Psychology Georg-August-University GöttingenGöttingenGermany Department of Immunology Rappaport Faculty of MedicineTechnion-Israel Institute of TechnologyHaifaIsrael Infection Immunology Institute for Medical Microbiology and Hospital HygieneHealth Campus ImmunologyInfectiology and InflammationOtto-von-Guericke-University MagdeburgMagdeburgGermanyImmune RegulationHelmholtz Centre for Infection ResearchBraunschweigGermany Department of Vaccinology and Applied Microbiology Helmholtz Centre for Infection ResearchBraunschweigGermany Institute of Virology Medical University MünsterMünsterGermany Institute of Virology Hannover Medical School(MHH)HannoverGermany German Centre for Infection Research(DZIF) Hannover-Braunschweig SiteHannoverGermany Centre for Individualized Infection medicine(CiiM) a joint venture of HZI and MHHHannoverGermany

Global pandemics caused by influenza or coronaviruses cause severe disruptions to public health and lead to high morbidity and *** remains a medical need for vaccines against these ***(cytomegalovirus)is aβ-herpesvirus that induces uniquely robust immune responses in which remarkably large populations of antigen-specific CD8+T cells are maintained for a ***,CMV has been proposed and investigated as a novel vaccine vector for expressing antigenic peptides or proteins to elicit protective cellular immune responses against numerous *** generated two recombinant murine CMV(MCMV)vaccine vectors expressing hemagglutinin(HA)of influenza A virus(MCMV^(HA))or the spike protein of severe acute respiratory syndrome coronavirus 2(MCMV^(S)).A single injection of MCMVs expressing either viral protein induced potent neutralizing antibody responses,which strengthened over ***,MCMV^(HA)-vaccinated mice were protected from illness following challenge with the influenza virus,and we excluded that this protection was due to the effects of memory T ***,we show here that MCMV vectors induce not only long-term cellular immunity but also humoral responses that provide long-term immune protection against clinically relevant respiratory pathogens.

关键词： Vaccine vector SARS-CoV-2 Influenza Cytomegalovirus humoral imunity

Exploring the Future of Malawi’s Environment Using Scenarios Approach

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International Journal of Geosciences 2017年第6期8卷 837-856页

作者： Geoffrey Chavula Feston Zambezi Mathews Tsirizeni Michael Mmangisa Yanira Ntupanyama Kenneth Gondwe Tawonga Mbale luka Sosten Chiotha Leadership for Environment and Development-Southern and Eastern Africa (LEAD-SEA) Zomba Malawi

Discussed in this paper are results of the study that was conducted as part of the process of compiling Malawi’s State of the Environment and Outlook Report for the year 2010. The status of the country’s economy and the nature of governance were identified as critical drivers, i.e., “critical uncertainties”, in determining the future state of the environment in Malawi. Four environmental scenarios were developed, namely: Scenario 1: “Mkaka ndi Uchi”, a combination of good economy and good governance;Scenario 2: “Penda Penda”, a combination of poor economy and good governance;Scenario 3: “Wafa Wafa”, a combination of poor economy and poor governance;and Scenario 4: “Chonchobe/Ndawonera Momwemo”, a combination of good economy and poor governance. Each of the four scenarios will be uniquely influenced by the prevailing economic and governance situation in the country, and hence impact differently on Malawi’s environment. Economy and Governance were selected as critical determinants out of seven key environmental drivers: demography, governance, social change, economy, environment and climate change, technology, and culture and tradition. From the above listed scenarios, it is only Scenario 1, Mkaka ndi Uchi, which will result in a prosperous Malawi while the rest portend the prevalence of a chaotic situation in the country, more so Scenario 3, the Wafa Wafa scenario.

关键词： Scenario Mkaka ndi Uchi Penda Penda Wafa Wafa Chonchobe/Ndawonera Momwemo

1988年微波理论和技术分类提要：微波声学的磁学现状与未来

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电光系统 1989年第4期 52-53页

作者： luka.,TJ 陈仪伟

西妥昔单抗联合奥沙利铂治疗头颈部鳞癌HN5裸鼠移植瘤的实验研究

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临床肿瘤学杂志 2007年第5期12卷 321-324页

作者：陆雪官 luka Milas 苏州大学附属第二医院肿瘤放射治疗科美国德州大学M.D.Anderson肿瘤中心实验放射肿瘤学系 tx77030

目的：观察阻断EGFR的西妥昔单克隆抗体（cetuximab，C225）是否能提高奥沙利铂（OXA）对头颈部鳞癌细胞株HN5移植瘤的抗瘤效应。方法：建立裸鼠移植瘤模型50只，当裸鼠右大腿的肿瘤直径达到8．0mm（7．6～8．3mm）时开始实验。实验共分... 详细信息

目的：观察阻断EGFR的西妥昔单克隆抗体（cetuximab，C225）是否能提高奥沙利铂（OXA）对头颈部鳞癌细胞株HN5移植瘤的抗瘤效应。方法：建立裸鼠移植瘤模型50只，当裸鼠右大腿的肿瘤直径达到8．0mm（7．6～8．3mm）时开始实验。实验共分5组（每组10只），分别为对照组、单用C225组、单用OXA组、C225＋OXA（6h）组和C225＋OXA（24h）组。观察指标为肿瘤生长延迟时间（肿瘤从8．0mm生长至12．0mm所需时间）和肿瘤治愈的情况。结果：除C225＋OXA（6h）组中有1只荷瘤裸鼠在治疗过程中死亡外，其余荷瘤裸鼠有8只肿瘤消失，其中单用C225组和单用OXA组各1只，C225＋OXA（6h）组有4只，C225＋OXA（24h）组有2只。余下41只的裸鼠肿瘤生长情况为：单用C225组和单用OXA组的绝对延迟时间分别为（21．4±8．2）天和（2．7±2．4）天，而C225＋OXA（6h）组和C225＋OXA（24h）组的绝对延迟时间则分别为（32．5±8．1）天和（30．0±10．4）天，其标准化的延迟时间分别为（11．1±8．1）天和（8．6±10．4）天，增益因子分别为4．11和3．19。结论：C225能提高OXA对头颈部鳞癌细胞株HN5移植瘤的抗瘤效应。

关键词：头颈部肿瘤化学疗法表皮生长因子受体单克隆抗体西妥昔单抗(C225) 奥沙利铂动物实验

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EGFR靶向抑制剂在肿瘤放射治疗中的应用

国际肿瘤学杂志 2006年第4期33卷 316-318页

作者：陆雪官 luka Milas 苏州大学附属第二医院放射治疗科 215004

大部分实体肿瘤有表皮生长因子受体(EGFR)的高表达,并且其高表达能显著降低肿瘤细胞的放射敏感性。近年来,开发了针对EGFR的靶向抑制剂,并且在临床前期研究和临床应用中发现其能提高一部分肿瘤对放射治疗的敏感性。现对EGFR的结构和信... 详细信息

大部分实体肿瘤有表皮生长因子受体(EGFR)的高表达,并且其高表达能显著降低肿瘤细胞的放射敏感性。近年来,开发了针对EGFR的靶向抑制剂,并且在临床前期研究和临床应用中发现其能提高一部分肿瘤对放射治疗的敏感性。现对EGFR的结构和信号传导途径、EGFR 的表达对肿瘤放射治疗预后的影响及其机制和其靶向抑制剂在放射治疗中的应用研究作一综述。

关键词：肿瘤受体表皮生长因子放射疗法