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How to improve colon cancer screening rates

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World Journal of Gastrointestinal Oncology 2015年第12期7卷 484-491页

作者： luiz ronaldo alberti Diego Paim Carvalho Garcia Debora Lucciola Coelho David Correa Alves De Lima Andy Petroianu Department of Surgery Federal University of Minas Gerais Medical Sciences of Minas Gerais

Colorectal carcinoma is a common cause of death throughout the world and may be prevented by routine control, which can detect precancerous neoplasms and early cancers before they undergo malignant transformation or metastasis. Three strategies may improve colon cancer screening rates: convince the population about the importance of undergoing a screening test; achieve higher efficacy in standard screening tests and make them more available to the community and develop new more sensitive and efficacious screening methods and make them available as routine tests. In this light, the present study seeks to review these three means through which to increase colon cancer screening rates.

关键词： Colon cancer screening Colon cancer Screening test

Association between thrombomodulin and high mobility group box 1 in sepsis patients

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World Journal of Critical Care Medicine 2020年第4期9卷 63-73页

作者： Adriana Teixeira Rodrigues Julia Teixeira Rodrigues Carolina Teixeira Rodrigues Caroline Maria de Oliveira Volpe Fabiana Rocha-Silva Jose Augusto Nogueira-Machado luiz ronaldo alberti Department of Pediatrics School of MedicineFederal University of Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and Research Belo Horizonte 30150-240Minas GeraisBrazil Department of Pharmacy Federal University of Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil Department of Internal Medicine Unimed HospitalBelo Horizonte 30150-340Minas GeraisBrazil Department of Immunology Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and ResearchBelo Horizonte 30150-240Minas GeraisBrazil Clinical Laboratory Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and ResearchBelo Horizonte 30150-240Minas GeraisBrazil Department of Surgery School of MedicineFederal University of Minas GeraisBelo Horizonte 30220-000Minas GeraisBrazil

BACKGROUND High mobility group box 1(HMGB1)has been studied as a molecule associated with severe outcomes in sepsis and thrombomodulin(TM)seems to decrease HMGB1 *** To investigate the role of the thrombomodulin/high mobility group box 1(T/H)ratio in patients with sepsis and their association with their clinic,testing the hypothesis that higher ratios are associated with better *** Twenty patients diagnosed with sepsis or septic shock,according to the 2016 criteria sepsis and septic shock(Sepsis-3),were *** were followed until they left the intensive care unit or until they achieved 28 d of hospitalization(D28).The following clinical outcomes were observed:Sequential Organ Failure Assessment(SOFA)score;Need for mechanical pulmonary ventilation;Presence of septic shock;Occurrence of sepsis-induced coagulopathy;Need for renal replacement therapy(RRT);and *** The results showed that patients with SOFA scores greater than or equal to 12 points had higher serum levels of TM:76.41±29.21 pg/mL vs 37.41±22.55 pg/mL among those whose SOFA scores were less than 12 points,P=*** T/H ratio was also higher in patients whose SOFA scores were greater than or equal to 12 points,P=*** T/H ratio was,on average,three times higher in patients in need of RRT(0.38±0.14 vs 0.11±0.09),P<*** Higher serum levels of TM and,therefore,higher T/H ratio in the first 24 h after the diagnosis of sepsis were associated with more severe disease and the need for renal replacement therapy,while those with better clinical outcomes and those who were discharged before D28 showed a tendency for lower T/H ratio values.

关键词： High mobility group box 1 Sepsis Thrombomodulin Renal replacement therapy Mechanical ventilation Septic shock

Mathematical simulation of radial heat transfer in packed beds by pseudohomogeneous modeling

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Particuology 2011年第2期9卷 107-113页

作者： Rodrigo Béttega Marcos Flávio Pinto Moreira ronaldo Guimaraes Corrêa José Teixeira Freire Federal University of Uberlandia/School of Chemical Engineering-Av.Jo o Naves ávila 2121 Uberlandia-MGCEP 38400-902Brazil Western Paraná State University-Rua da Faculdade 645 Jardim La SalleToledo-PRCEP 85903-000Brazil Federal University of S o Carlos/Department of Chemical Engineering-Rod.Washington luiz km 235 S o Carlos-SPCEP 13565-905P.O.Box 676Brazil

Uniform flow regime and constant effective thermal conductivity inside packed beds are commonly accepted in the evaluation of the fluid dynamics and heat transfer in such systems. However, several authors have confirmed the presence of an oscillatory velocity profile caused by the effective contribu~ tion of porosity profile in the fluid dynamic behavior of packed beds, which directly influences the heat transfer inside the beds. This paper describes the application of a pseudo-homogeneous mathematical model for describing heat transfer in packed beds with oscillatory profiles of velocity and porosity, using a radius-dependent model for effective thermal conductivity kr. Several temperature profiles were obtained in a packed bed system with thermal source located on the wall. The simulated temperature and effective thermal conductivity obtained from simulations were compared with experimental data and calculation from a model based on uniform kr fitting. The results indicate that the proposed mathematical modeling was capable of better reDresenting the heat transfer in the packed bed.

关键词： Packed bedHeat transferPseudohomogeneous modeling

Structural and Production Characteristics of PiatãGrass Forage Submitted to Levels of Nitrogen

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American Journal of Plant Sciences 2015年第5期6卷 693-701页

作者： ronaldo Liberato Dourado Alexandre Lima de Souza Anderson de Moura Zanine Fabio luiz Buranelo Toral Daniele de Jesus Ferreira Joadil Goncalves de Abreu Department of Science and Technology Federal Institute of EducationBrasiliaBrazil Department of Animal Science Federal University of Mato GrossoCuiabáBrazil Department of Animal Science Federal University of Minas GeraisBelo HorizonteBrazil

Piatã grass (Brachiaria brizantha cv. Piatã) is a tropical grass cultivating in pasture production system. The aim of this study was to evaluate the effects of nitrogen levels (0, 125, 250, 375 and 500 kg·N·ha-1) on structural characteristics and forage production of Piatã grass. The experiment comprised of twenty grass parcels arranged in randomised completely casualties design. This study was carried out between November of 2007 and April of 2008, with 175 experimental days. A quadratic effect (P ·m-2 at a nitrogen dose of 357 kg·ha-1. A quadratic effect (P ·ha-1·year-1?for nitrogen levels of 411 and 384 kg·ha-1, respectively. However, a considerable portion of forage production obtained by nitrogen addition occurred from stem production. The productions of green leaf blade dry matter, tiller density, leaf blade length and leaf blade index are all variables related to structural aspects and pasture quality, with all attaining their highest values at a mean nitrogen application level of 380 kg·ha-1.

关键词： Forage Accumulation Frequencies Cuts Leaf Area Index Tiller Density

Iterative Estimation for Flight Dynamic Helicopter Simulator

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Journal of Mathematics and System Science 2015年第12期5卷 501-508页

作者： Ivana Yoshie Sumida Haroldo F. de Campos Velho Eduardo F. P. da Luz ronaldo V. Cruz luiz CarlosS. Goes pplied Computing Graduate Program National Institute for Space Research (1NPE) Brazil Flight Test Research Institute (IPEV) Brazil Associated Laboratory for Computing andApplied Mathematics National Institute for Space Research (INPE) Brazil Department of Mechanical Engineering Technological Institute of Aeronautics (ITA) Brazil

Flight simulators can provide a suitable alternative to real flight, mainly to increase safety through the training of crew, and evaluation data from simulator can be used to validation and certification of aircraft systems. However, it must convey some degree of realism to the user to be effective. For that reason, it is necessary to calibrate the simulator software. Calibration for flight simulation is parameter identification process. The process is formulated as an optimization problem, and it is solved by using a new approach named Multiple Particle Collision Algorithm （MPCA）. Results show a good performance for the employed approach.

关键词： Dynamic Flight Parameter Identification Multiple Particle Collision Algorithm