检索结果-南通市图书馆

Dehydrated Natural feed for Cats: Influence on Apparent Digestibility Coefficient, feces Scores, and Serum Immune, Antioxidant, and Metabolic Biomarkers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

food and Nutrition Sciences 2024年第7期15卷 594-611页

作者： Bruno Giorgio de Oliveira Cécere Guilherme luiz Deolindo Bianca f. Bissacotti Priscila Marquezin Copetti Maria Rosa Chitolina Schetinger Bruna Klein Matheus Delamea Baldissera Thiago Pereira Ribeiro Walter Hugo Cuelho Suarez Daniel Pigatto Monteiro Aleksandro Schafer Da Silva Graduate Multicenter Program in Biochemistry and Molecular Biology University of the State of Santa Catarina Lages Brazil Department of Biochemistry and Molecular Biology Universidade Federal de Santa Maria (UFSM) Santa Maria Brazil Department of Animal Science Universidade Federal de Santa Maria (UFSM) Chapec Brazil Department of Health Science Universidade Franciscana (UFN) Santa Maria Brazil Department of Animal Nutrition Tectron-Tecnologia e Inovao Toledo Brazil

The present study aimed to determine whether natural dehydrated feed (DNf) can replace dry extruded feed while preserving the required daily intake, nutrient digestibility and benefits for immunity and antioxidant response in cats. The animals were divided into two groups of seven animals each. One group received DNf, and the other consumed commercial extruded dry feed (DCf). The experiment lasted 45 days and we measured daily consumption and collected blood and feces samples. The animals in the DNf group showed greater digestibility of fiber and mineral matter than DCf. Cats in the DNf group had a higher volume of feces. DNf cats had lower leukocyte and granulocyte counts and cholesterol levels. Serum enzymatic antioxidant responses and non-enzymatic were higher in DNf cats. Cats in the DNf group showed lower serum acute phase proteins in addition to a tendency toward a higher concentration of transferrin than in the DCf group. fecal Escherichia coli and total coliform counts of cats fed DNf were higher than DCf. We conclude that the daily consumption of cats is adequate. This feed had greater digestibility of fiber and mineral matter, in addition to an improvement in antioxidant and immunological responses.

关键词： Alternative feed Antioxidant Companion Animals Health

The transient receptor potential melastatin 2:a new therapeutical target for Parkinson's disease?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第8期18卷 1652-1656页

作者： Ana flávia f.ferreira luiz Roberto G.Britto Department of Physiology and Biophysics Institute of Biomedical SciencesUniversity of São PauloSão PauloBrazil

The transient receptor potential melastatin 2 is a calcium-permeable cation channel member of the TRP family. Also known as an oxidative stress-activated channel, the transient receptor potential melastatin 2 gating mechanism is dependent on reactive oxygen species. In pathological conditions, transient receptor potential melastatin 2 is overactivated, leading to a Ca~(2+) influx that alters cell homeostasis and promotes cell death. The role of transient receptor potential melastatin 2 in neurodegenerative diseases, including Alzheimer's disease and ischemia, has already been described and reviewed. However, data on transient receptor potential melastatin 2 involvement in Parkinson's disease pathology has emerged only in recent years and the issue lacks review studies that focus specifically on this topic. The present review aims to elucidate the role of the transient receptor potential melastatin 2 channel in Parkinson's disease by reviewing, summarizing, and discussing the in vitro, in vivo, and human studies published until August 2022. Here we describe fourteen studies that evaluated the transient receptor potential melastatin 2 channel in Parkinson's disease. The Parkinson's disease model used, transient receptor potential melastatin 2 antagonist and genetic approaches, and the main outcomes reported were discussed. The studies described transient receptor potential melastatin 2 activation and enhanced expression in different Parkinson's disease models. They also evidenced protective and restorative effects when using transient receptor potential melastatin 2 antagonists, knockout, or silencing. This review provides a literature overview and suggests where there is a need for more research. As a perspective point, this review shows evidence that supports transient receptor potential melastatin 2 as a pharmacological target for Parkinson's disease in the future.

关键词： 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine(MPTP) 1-methyl-4-phenylpyridinium(MPP+) 6-hydroxydopamine AG490 clotrimazole flufenamic acid N-(p-amylcinnamoyl)anthranilic acid Parkinson's disease poly-ADPR polymerase type 1(PARP1) rotenone paraquat transient receptor potential melastatin 2(TRPM2)

The nest architecture of the ant, Pheidole oxyops forel, 1908 （Hymenoptera： formicidae）

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insect Science 2007年第5期14卷 437-442页

作者： luiz C. fORTI ROBERTO S. CAMARGO RICARDO T. fUJIHARA JULIANE f. S. LOPES Laboratorio de Insetos Sociais-Praga Departamento de Producao Vegetal - Setor Defesa Fitossanitaria FCA/UNESP Botucatu SP Comportamento e Ecologia Animal Instituto de Ciencias Biologicas Universidade Federal de Juiz de Fora Campus Universitario Martelos Juiz de Fora MG Brazil

Pheidole oxyops builds subterranean nests, with an external architecture that is distinctive and easily recognizable by its wide and specific entrance hole, measuring up to 12.2 cm in diameter, denoting a pitfall-trap. In order to study the nests＇ internal architecture, seven nests were excavated; four were identified with neutral talc, while the others were cast in cement and then excavated. Measurements were made in order to gain a better understand- ing of their structures, and a photographic documentation was obtained as well. The excavations revealed that the nests are perpendicular relative to the ground, beginning with a cylindrical channel with a mean length of 13.5 cm, containing irregular formations, and whose diameter becomes progressively narrower until the first chamber is formed. As the channel continues, dish-like chambers appear, interconnected by channels that become progressively narrower and longer, while the chambers are arranged at greater distances from each other as nest depth increases. Both channels and chambers are located on the vertical projection of the entrance hole. Nests may reach a depth of up to 5.09 m, with a number of chambers ranging between 4 and 14.

关键词： chambers nest architecture Pheidole pitfall-trap

Current aspects of renal dysfunction after liver transplantation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2022年第1期14卷 45-61页

作者： Mariana P Pacheco luiz Augusto Carneiro-D'Albuquerque Daniel f Mazo Division of Clinical Gastroenterology and Hepatology Department of GastroenterologyUniversity of São Paulo School of MedicineSao Paulo 05403-900Sao PauloBrazil Division of Digestive Organs Transplant Department of GastroenterologyUniversity of São Paulo School of MedicineSao Paulo 05403-900Sao PauloBrazil Division of Gastroenterology Department of Internal MedicineSchool of Medical Sciences of University of CampinasCampinas 13083-878Sao PauloBrazil

The development of chronic kidney disease(CKD)after liver transplantation(LT)exerts a severe effect on the survival of *** widespread adoption of the model for end-stage liver disease score strongly impacted CKD incidence after the procedure,as several patients are transplanted with previously deteriorated renal *** to its multifactorial nature,encompassing pre-transplantation conditions,perioperative events,and nephrotoxic immunosuppressor therapies,the accurate identification of patients under risk of renal disease,and the implementation of preventive approaches,are extremely *** for the evaluation of renal function in this setting range from formulas that estimate the glomerular filtration rate,to non-invasive markers,although no option has yet proved efficient in early detection of kidney *** the nephrotoxicity of calcineurin inhibitors(CNI)as a factor of utmost importance after LT,early nephroprotective strategies are highly *** are based mainly on delaying the application of CNI during the immediate postoperativeperiod,reducing their dosage,and associating them with other less nephrotoxic drugs,such as mycophenolate mofetil and *** review provides a critical assessment of the causes of renal dysfunction after LT,the methods of its evaluation,and the interventions aimed at preserving renal function early and belatedly after LT.

关键词： Liver transplantation Acute kidney injury Chronic kidney disease Calcineurin inhibitor Mycophenolic acid Everolimus

Successful liver allograft inflow reconstruction with the right gastroepiploic vein

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2016年第1期15卷 106-110页

作者： Rafael S Pinheiro Ruy J Cruz Jr Lucas S Nacif Matheus f Vane luiz AC D'Albuquerque Liver Transplant Division Department of GastroenterologyUniversity of S?o Paulo School of Medicine Department of Anesthesiology University of S?o Paulo School of Medicine

Portal vein thrombosis is a common complica- tion in cirrhotic patients. When portal vein thrombectomy is not a suitable option, a large collateral vessel can be used for allograft venous inflow reconstruction. We describe an unusu- al case of successful portal revascularization using the right gastroepiploic vein. The patient underwent a cadaveric or- thotropic liver transplantation with end-to-end anastomosis of the portal vein to the right gastroepiploic vein. Six months after liver transplantation the patient is well with good liver function. The use of the right gastroepiploic vein for allograft venous reconstruction is feasible and safe, with a great advan- tage of avoiding the need of venous jump graft.

关键词： liver transplantation vascular grafting portal vein, cavernous transformation of varicose veins hypertension, portal

Cumulative positive fluid balance is a risk factor for acute kidney injury and requirement for renal replacement therapy after liver transplantation

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Transplantation 2018年第2期8卷 44-51页

作者： Liana Codes Ygor Gomes de Souza Ricardo Azevedo Cruz D'Oliveira Jorge luiz Andrade Bastos Paulo Lisboa bittencourt Unit of Gastroenterology and Hepatology Portuguese Hospital of Salvador Medical School of Bahia Federal University of Bahia

AIM To analyze whether fluid overload is an independent risk factor of adverse outcomes after liver transplantation(LT).METHODS One hundred and twenty-one patients submitted to LT were retrospectively *** regarding perioperative and postoperative variables previously associated with adverse outcomes after LT were *** fluid balance(fB) in the first 12 h and 4 d after surgery were compared with major adverse outcomes after *** Most of the patients were submitted to a liberal approach of fluid administration with a mean cumulative fBover 5 L and 10 L,respectively,in the first 12 h and 4 d after *** fB in 4 d was independently associated with occurrence of both AKI and requirement for renal replacement therapy(RRT)(OR = 2.3;95%CI:1.37-3.86,P = 0.02 and OR = 2.89;95%CI:1.52-5.49,P = 0.001 respectively).Other variables on multivariate analysis associated with AKI and RRT were,respectively,male sex and Acute Physiology and Chronic Health Disease Classification System(APACHE II) levels and sepsis or septic *** was shown to be independently related to AST and APACHE II levels(OR = 2.35;95%CI:1.1-5.05,P = 0.02 and 2.63;95%CI:1.0-6.87,P = 0.04 respectively),probably reflecting the degree of graft dysfunction and severity of early postoperative course of *** effect of fB on mortality after LT was *** Cumulative positive fB over 4 d after LT is independently associated with the development of AKI and the requirement of *** was not independently related to fB,but to surrogate markers of graft dysfunction and severity of postoperative course of LT.

关键词： Liver transplantation fluid balance Acute kidney injury

Numerical modeling of adhesion and adhesive failure during unidirectional contact between metallic surfaces

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

friction 2016年第3期4卷 217-227页

作者： Eleir M.BORTOLETO Erika f.PRADOS Vanessa SERIACOPI Newton K.fUKUMASU luiz G.D.B.da S.LIMA Izabel f.MACHADO Roberto M.SOUZA Surface Phenomena Laboratory Department of Mechanical Engineering Polytechnic School of the University of S(a)o Paulo Av.Prof.Mello Moraes 2231 S(a)o Paulo 05508-900 Brazil federal University of ABC-UfABC Santo André 09210-170 Brazil

In this work, we developed a finite element modeling approach to study adhesion during unidirectional contact between a two-dimensional plane-strain square and a flat slab. The surfaces were metallic or ceramic, and we analyzed different pairs of materials and their adhesion intensity using a fORTRAN subroutine (DLOAD) connected to a commercial finite element code Abaqus, which provided the surface attractive forces based on the Lennard-Jones interatomic potential using Hamaker constants. We considered adhesive loads during both the approach and separation of the surfaces. During the separation step, we modeled the material transfer between surfaces due to adhesion with respect to damage initiation and propagation at the flat slab. The parameters considered in the simulations include normal load, chemical affinity, and system size, and we analyzed different conditions by comparing the interaction forces during approach and withdrawal. This work also presents: (i) a description of the evolution of energy dissipation due to adhesion hysteresis, (ii) the formation–growth–breakage process of the adhesive junctions and the material transfer between surfaces, and (iii) an adhesive wear map based on a proposed novel equation that correlates the material parameters and material loss due to adhesion. The results indicate that the chemical affinity between bodies in contact is more related to adhesion than the applied load. In addition, the ratio between the material strength and elastic modulus seems to be an important factor in reducing adhesive wear.

关键词： adhesion adhesive failure finite element model interatomic potentials Hamaker constants

Influence of physical and chemical factors during foraging and culture of the symbiont fungus in Atta sexdens rubropilosa （Hymenoptera： formicidae）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2007年第4期14卷 295-300页

作者： SANDRA S. VERZA luiz C. fORTI JULIANE f. S. LOPES ROBERTO S.CAMARGO CARLOS A. O. MATOS Departamento de Zoologia Instituto de Biociencias Laboratrio de Insetos Sociais-Praga Departamento de Produ~~o Vegetal-Def-esa Fitossanitaria Faculdade de Ciencias Agronomicas UNESP-Sao Paulo State University Fazenda Experimental LageadoBotucatu SP Comportamento e Biologia Animal Instituto de Ciencias Biologicas UFJF-Universidade Federal de Juiz de ForaCampus Universitario Martelos Juiz de Fora MG Campus Experimental de Itapeva UNESP Itapeva SP Brazil

The aim of this paper is to investigate the influence of physical and chemical factors on transport and use of substrate for Atta sexdens rubropilosa workers. Three types of rectangular fragments were used to study the physical influence factors： filter paper with paraffin, filter paper without paraffin and polyester film. To study the chemical factors, some fragments were impregnated with organic extract of orange albedo, others were soaked with soybean oil and for the remaining ones nothing was applied. The fonowing parameters were evaluated：（i） attractiveness of substrate for transport and number of loading workers per treatment; （ii） foraged material incorporation; （iii） rejection by numbers of fragments deposited in the garbage or beside the fungus garden. All the polyester film fragments carried out to the fungus garden were subsequently rejected. We verified that chemical factors of the substrate were more quickly detected by the workers, whereas physical factors were used as a criterion in the decision-making to reject or accept the substrate collected.

关键词： Atta sexdens rubropilosa attractiveness behavior leaf-cutting ants substraterejection substrate selection

Genomic and transcriptomic analyses enable the identification of important genes associated with subcutaneous fat deposition in Holstein cows

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2023年第6期50卷 385-397页

作者： Hailiang Zhang Siyuan Mia luiz f.Brito Lirong Hu Lei Wang Longgang Ma Qing Xu Gang Guo Ying Yu Yachun Wang Laboratory of Animal Genetics Breeding and ReproductionMinistry of Agriculture of ChinaNational Engineering Laboratory of Animal BreedingCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Department of Animal Sciences Purdue UniversityWest LafayetteIN 47907USA Institute of Life Sciences and Bioengineering Beijing Jiaotong UniversityBejing 100044China Beijing Sunlon Livestock Development Co.Ltd Beijing 100176China

Subcutaneous fat deposition has many important roles in dairy cattle,including immunological defense and mechanical *** main objectives of this study are to identify key candidate genes regulating subcutaneous fat deposition in high-producing dairy cows by integrating genomic and transcriptomic datasets.A total of 1654 genotyped Holstein cows are used to perform a genome-wide association study(GWAS)aiming to identify genes associated with subcutaneous fat ***,weighted gene co-expression network analyses(WGCNA)are conducted based on RNA-sequencing data of 34 cows and cow yield deviations of subcutaneous fat ***,differentially expressed(DE)m RNA,lnc RNA,and differentially alternative splicing genes are obtained for 12 Holstein cows with extreme and divergent phenotypes for subcutaneous fat ***-six protein-coding genes are identified as candidate genes regulating subcutaneous fat deposition in Holstein cattle based on *** overlapping genes are identified based on the analyses of DE genes and ***,the candidate genes identified based on GWAS,WGCNA,and analyses of DE genes are significantly enriched for pathways involved in metabolism,oxidative phosphorylation,thermogenesis,fatty acid degradation,and glycolysis/gluconeogenesis *** all findings,the NID2,STARD3,UfC1,DEDD,PPP1R1B,and USP21 genes are considered to be the most important candidate genes influencing subcutaneous fat deposition traits in Holstein *** study provides novel insights into the regulation mechanism underlying fat deposition in high-producing dairy cows,which will be useful when designing management and breeding strategies.

关键词： Bovine Body condition score Subcutaneous adipose GWAS WGCNA RNA-Seq