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Motor competence and health-related fitness in children:A cross-cultural comparison between Portugal and the United States

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Journal of Sport and Health Science 2019年第2期8卷 130-136页

作者： Carlos Luz Rita Cordovil luis paulo rodrigues Zan Gao Jacqueline D.Goodway Ryan S.Sacko Danielle R.Nesbitt Rick C.Ferkel Larissa K.True David F.Stodden Escola Superior de Educaeao de Lisboa Instituto Politecnico de Lisboa & CIED CIPER Faculdade de Motricidade Humana Universidade de Lisboa Escola Superior de Desporto e Lazer de Melgaqo Instituto Politecnico de Viana do Castelo Research Center in Sports Health and Human Development (CIDESD) School of Kinesiology The University of Minnesota Department of Human Sciences The Ohio State University Department of Health and Human Performance Department of Physical Education University of South Carolina Physical Education & Sport Central Michigan University Kinesiology Department State University of New York at Cortland

Background: Motor competence and health-related fitness are important components for the development and maintenance of a healthy lifestyle in children. This study examined cross-cultural performances on motor competence and health-related fitness between Portuguese and ***: Portuguese(n = 508; 10.14 § 2.13 years, mean § SD) and U.S.(n = 710; 9.48 § 1.62 years) children performed tests of cardiorespiratory fitness(Progressive Aerobic Cardiovascular Endurance Run), upper body strength(handgrip), locomotor skill performance(standing long jump), and object projection skill performance(throwing and kicking). Portuguese and U.S. children were divided into 2 age groups(6à9 and 10à13 years) for data analysis purposes. A twoàfactor oneàway analysis of covariance(ANOVA) was conducted with the Progressive Aerobic Cardiovascular Endurance Run, handgrip, standing long jump scores, kicking, and throwing speed(km/h) as dependent ***: Results indicated that Portuguese children, irrespective of sex, presented better performances in locomotor and cardiorespiratory performance(standing long jump and Progressive Aerobic Cardiovascular Endurance Run) than U.S. children in both age bands. U.S. children outperformed Portuguese children during throwing and handgrip tests. Kicking tests presented gender differences: Portuguese boys and U.S. girls outperformed their internationally matched ***: Cultural differences in physical education curricula and sports participation may impact differences in motor competence and fitness development in these countries.

关键词： Children Cross-cultural comparison Health-related fitness Motor competence

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Sarcopenia and Anemia Are Predictors of Poor Prognostic in Cervical Cancer Patients

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Open Journal of Obstetrics and Gynecology 2024年第5期14卷 693-704页

作者： Leandro Santos de Araujo Resende Francine Vilela de Amorim Miguel Soares Conceição Rodrigo Menezes Jales Patrick Nunes Pereira luis Otávio Sarian Glauco Baiocchi Sophie Derchain Agnaldo Lopes da Silva Filho Department of Gynecology and Obstetrics Botucatu Medical School S&#227o Paulo State University UNESP S&#227o Paulo Brazil Department of Health Sciences University of Sao Francisco S&#227o Paulo Brazil Department of Obstetrics and Gynecology School of Medical Science State University of Campinas (UNICAMP) Campinas Brazil Department of Gynecologic Oncology AC Camargo Cancer Center Sao Paulo Brazil Department of Gynecology and Obstetrics School of Medicine of the Federal University of Minas Gerais Belo Horizonte Brazil

Objective: Evaluate pretreatment sarcopenia and anemia as prognostic factors in women undergoing treatment for cervical cancer (CC) with concurrent chemoradiotherapy (CCRT). Methods: 151 women with CC were analysed in this cohort study. Pretreatment computed tomography (CT) images were analysed to assess skeletal muscle index (SMI). Hazard ratios (HR) and multivariate Cox proportional HR were used to analyse association between low SMI, age, body mass index (BMI), haemoglobin levels, histological type, and International Federation of Gynaecology and Obstetrics (FIGO) stage with PFS and OS. Results: A total of 151 patients were included, 53 (35.1%) presented pretreatment sarcopenia;51 (34%) stage I/II and 100 (66%) stage III/IV. Among those patients in advanced stage (III/IV) 37 (70%) (p = 0.28) were sarcopenic at the beginning of treatment. Sarcopenia was associated with worse progression-free survival (PFS) and overall survival (OS) in our cohort [HR 0.97 (p = 0.01)] [HR 0.73 (p = 0.001)], as well as anemia [HR 0.73 (p = 0.001)] [HR 0.78 (p = 0.001)]. Linear regression models indicated that despite showing no association with age, neutrophil or platelet counts, sarcopenia was associated with pretreatment anemia levels (p = 0.01). After a multivariate analysis, only haemoglobin (anemia) and complete CCRT remained associated with PFS and OS. Sarcopenia and anemia were associated with worse PFS and OS in FIGO stage I/II. Conclusion: Pretreatment sarcopenia was significantly associated with low haemoglobin levels. Anemia and incomplete CCRT were independently associated with poor prognosis in women with CC. Pretreatment sarcopenia, as low SMI, was a predictor of poor prognostic in early stages of CC.

关键词： Cervical Cancer Sarcopenia Anemia Chemoradiotherapy

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Particulate matter geochemistry of a highly industrialized region in the Caribbean:Basis for future toxicological studies

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Geoscience Frontiers 2022年第1期13卷 376-387页

作者： luis F.O.Silva Ismael L.Schneider paulo Artaxo Yuleisy Núñez-Blanco Diana Pinto Érico M.M.Flores Leandro Gómez-Plata Omar Ramírez Guilherme L.Dotto Department of Civil and Environmental Universidad de la CostaCUCCalle 58#55–66BarranquillaAtlánticoColombia Department of Applied Physics Institute of PhysicsUniversity of São PauloBrazil Department of Chemistry Universidade Federal de Santa MariaRSBrazil Universidad Militar Nueva Granada(UMNG) Faculty of EngineeringEnvironmental EngineeringKm 2 Cajicá-ZipaquiráColombia Chemical Engineering Department Federal University of Santa Maria-UFSM1000Roraima Avenue97105-900 Santa MariaRSBrazil

Air pollution has become an important issue,especially in Caribbean urban areas,and,particulate matter(PM)emitted by different natural and anthropogenic sources causes environmental and health *** this work,we studied the concentrations of PM_(10) and PM_(2.5) sources in an industrial and port urban area in the Caribbean region of *** samples were collected within 48-h periods between April and October 2018 by using a Partisol 2000 i-D *** geochemical characterization was performed by X-ray fluorescence(XRF)***,ionic species and black carbon(BC)were quantified by ion chromatography and reflectance spectroscopy,*** the Positive Matrix Factorization(PMF)receptor model,the contributions of PM sources were *** average concentration of PM_(10) was 46.6±16.2μg/m^(3),with high concentrations of Cl and *** PM_(2.5),the average concentration was 12.0±3.2μg/m^(3),and the most abundant components were BC,S,and *** receptor model identified five sources for PM_(10) and PM_(2.5).For both fractions,the contributions of marine sea spray,re-suspended soil,and vehicular traffic were *** addition,PM_(2.5) included two mixed sources were found to be fuel oil combustion with fertilizer industry emissions,and secondary aerosol sources with building construction ***,PM_(10) was found to also include building construction emissions with re-suspended soil,and metallurgical industry *** obtained geochemical atmospheric results are important for the implementation of strategies for the continuous improvement of the air quality of the Caribbean region.

关键词： Urban air pollution Particulate matter Geochemical composition Aerosol source apportionment Receptor models PMF

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Developments in Land Use and Land Cover Classification Techniques in Remote Sensing: A Review

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Journal of Geographic Information System 2022年第1期14卷 1-28页

作者： Lucrêncio Silvestre Macarringue Édson luis Bolfe paulo Roberto Mendes Pereira Department of Geography Institute of Geosciences State University of Campinas Campinas Brazil Department of Research Instituto Politécnico de Ciências da Terra e Ambiente Matola Mozambique Embrapa Agricultura Digital Brazilian Agricultural Research Corporation Campinas Brazil

Studies on land use and land cover changes (LULCC) have been a great concern due to their contribution to the policies formulation and strategic plans in different areas and at different scales. The LULCC when intense and on a global scale can be catastrophic if not detected and monitored affecting the key aspects of the ecosystem’s functions. For decades, technological developments and tools of geographic information systems (GIS), remote sensing (RS) and machine learning (ML) since data acquisition, processing and results in diffusion have been investigated to access landscape conditions and hence, different land use and land cover classification systems have been performed at different levels. Providing coherent guidelines, based on literature review, to examine, evaluate and spread such conditions could be a rich contribution. Therefore, hundreds of relevant studies available in different databases (Science Direct, Scopus, Google Scholar) demonstrating advances achieved in local, regional and global land cover classification products at different spatial, spectral and temporal resolutions over the past decades were selected and investigated. This article aims to show the main tools, data, approaches applied for analysis, assessment, mapping and monitoring of LULCC and to investigate some associated challenges and limitations that may influence the performance of future works, through a progressive perspective. Based on this study, despite the advances archived in recent decades, issues related to multi-source, multi-temporal and multi-level analysis, robustness and quality, scalability need to be further studied as they constitute some of the main challenges for remote sensing.

关键词： Big Spatial Data Cloud Computing Machine Learning Remote Sensing

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Static-based early-damage detection using symbolic data analysis and unsupervised learning methods

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Frontiers of Structural and Civil Engineering 2015年第1期9卷 1-16页

作者： Joao Pedro SANTOS Christian CREMONA Andre D. ORCESI paulo SILVEIRA luis CALADO Department of Structures Av. Brasil 101 Lisbon 1700-066 Portugal Technical Center for Bridge Engineering CEREMA B.P. 214 Provins Cedex 77487 France Materials and Structures Department IFSTTAR University Paris-Est 14-20 Boulevard Newton Champs sur Marne Marne la Vallee Cedex2 F-77447 France Department of Civil Engineering Technical University Lisbon Avenida Rovisco Pais Lisbon 1096 Portugal

A large amount of researches and studies have been recently performed by applying statistical and machine learning techniques for vibration-based damage detection. However, the global character inherent to the limited number of modal properties issued from operational modal analysis may be not appropriate for early-damage, which has generally a local character. The present paper aims at detecting this type of damage by using static SHM data and by assuming that early-damage produces dead load redistribution. To achieve this objective a data driven strategy is proposed, consisting of the combination of advanced statistical and machine learning methods such as principal component analysis, symbolic data analysis and cluster analysis. From this analysis it was observed that, under the noise levels measured on site, the proposed strategy is able to automatically detect stiffness reduction in stay cables reaching at least 1%.

关键词： structural health monitoring early-damage detection principal component analysis symbolic data symbolic dissimilarity measures cluster analysis numerical model damage simulations

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Spatial distribution of morphometric parameters of glacial cirques in the Central Pyrenees(Aran and Boí valleys)

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Journal of Mountain Science 2018年第10期15卷 2103-2119页

作者： luis LOPES Marc OLIVA Marcelo FERNANDES paulo PEREIRA Pedro PALMA Jesús RUIZ-FERNáNDEZ Centre for Geographical Studies – IGOT Universidade de Lisboa Department of Geography University of Barcelona Environmental Management Center Mykolas Romeris University Department of Geography University of Oviedo

Glacial cirques are typical landscape features of mid-latitude mountain environments like the Central Pyrenees. Their morphology as well as their spatial distribution provides insights about past glaciers and climates. In this study, we examine the distribution, morphometrical and topographical characteristics of glacial cirques in two U-shaped glacial valleys located in the Central Pyrenees – the Aran and the Boí valleys. They are located in different aspects of this mountain range(north vs south) under different climatic influences that promoted distinct glaciation patterns during the late Pleistocene. The spatial mapping of these landforms was carried out using high-resolution imagery and field observations. We analysed the data of the morphometrical and topographical variables of the glacial cirques by using different statistical and geospatial methods in order tounveil the factors controlling their formation and development. A total of 186 glacial cirques were mapped in the study area, including 119 in the Aran and 67 in the Boí valleys. The local topography and microclimate conditions lead to substantial differences in both areas in terms of the morphology and dimensions of the cirques. Glacial cirques in Boí are distributed at slightly higher elevations than in Aran and they are also larger, though their dimensions decrease with elevation in both valleys. Aran cirques are mostly oriented NE, while Boí landforms do not show any prevailing aspect. Even though lithology does not control the distribution of the glacial cirques, some specific lithological settings may favour the development of larger cirques. In general, glacial cirques in the Aran and the Boí valleys show morphometrical properties similar to those reported in other mid-latitude mountain ranges.

关键词：冰斗冰川山谷山脉分发中央空间小气候条件

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An updated overview on the development of new photosensitizers for anticancer photodynamic therapy

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Acta Pharmaceutica Sinica B 2018年第2期8卷 137-146页

作者： Juan Zhang Chengshi Jiang Joao paulo Figueiró Longo Ricardo Bentes Azevedo Hua Zhang luis Alexandre Muehlmann School of Biological Science and Technology University of Jinan Institute of Biological Sciences University of Brasilia Faculty of Ceilandia University of Brasilia

Photodynamic therapy(PDT), based on the photoactivation of photosensitizers(PSs), has become a well-studied therapy for cancer. Photofrin~?, belonging to the first generation of PS, is still widely used for the treatment of different kinds of cancers; however, it has several drawbacks that significantly limit its general clinical use. Consequently, there has been extensive research on the design of PS molecules with optimized pharmaceutical properties, with aiming of overcoming the disadvantages of traditional PS, such as poor chemical purity, long half-life, excessive accumulation into the skin, and low attenuation coefficients. The rational design of novel PS with desirable properties has attracted considerable research in the pharmaceutical field. This review presents an overview on the classical photosensitizers and the most significant recent advances in the development of PS with regard to their potential application in oncology.

关键词： Anti-cancer Photosensitizers Photodynamic therapy Photochemical reactions Oncology BODIPY

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Numerical Methods for Solving the Hartree-Fock Equations of Diatomic Molecules I

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Communications in Computational Physics 2009年第5期5卷 959-985页

作者： John C.Morrison Scott Boyd luis Marsano Bernard Bialecki Thomas Ericsson Jose paulo Santos Department of Physics University of LouisvilleLouisvilleKY40292USA Department of Mathematical and Computer Sciences Colorado School of MinesGoldenCO 80401-1887USA Department of Mathematical Sciences Chalmers University of Technology and the University of GothenburgSE-41296 GothenburgSweden Department of Physics New University of LisbonLisbonPortugal

The theory of domain decomposition is described and used to divide the variable domain of a diatomic molecule into separate regions which are solved *** approach makes it possible to use fast Krylov methods in the broad interior of the region while using explicit methods such as Gaussian elimination on the *** is demonstrated by solving a number of model problems,these methods enable one to obtain solutions of the relevant partial differential equations and eigenvalue equations accurate to six significant figures with a small amount of computational *** the numerical approach described in this article decomposes the variable space into separate regions where the equations are solved independently,our approach is very well-suited to parallel computing and offers the long term possibility of studying complex molecules by dividing them into smaller fragments that are calculated separately.

关键词： Fast Krylov methods splines Hartree-Fock equations diatomic molecules eigenvalue problem

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Potential role of Limosilactobacillus fermentum as a probiotic with anti-diabetic properties: A review

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World Journal of Diabetes 2022年第9期13卷 717-728页

作者： Diego Cabral Lacerda paulo César Trindade da Costa Paula Brielle Pontes Lucas Alves Carneiro dos Santos JoséPatrocínio Ribeiro Cruz Neto Cristiane Cosmo Silva luis Vanessa Polyana de Sousa Brito JoséLuiz de Brito Alves Department of Nutrition Health Sciences CenterFederal University of ParaíbaJoão Pessoa58051-900ParaíbaBrazil Department of Neuropsychiatry Health Sciences CenterFederal University of PernambucoRecife50670-901PernambucoBrazil Department of Nutrition Federal University of ParaíbaJoão Pessoa58045-190ParaíbaBrazil

Oxidative stress,inflammation,and gut microbiota impairments have been implicated in the development and maintenance of diabetes *** capable of recovering the community of commensal gut microbiota and controlling diabetes mellitus have increased in recent *** lactobacilli strains have an antioxidant and anti-inflammatory system capable of protecting against oxidative stress,inflammation,and diabetes *** studies and some clinical trials have demonstrated that Limosilactobacillus fermentum strains can beneficially modulate the host antioxidant and anti-inflammatory system,resulting in the amelioration of glucose homeostasis in diabetic *** review presents and discusses the currently available studies on the identification of Limosilactobacillus fermentum strains with anti-diabetic properties,their sources,range of dosage,and the intervention time in experiments with animals and clinical *** review strives to serve as a relevant and well-cataloged reference of Limosilactobacillus fermentum strains capable of inducing anti-diabetic effects and promoting health benefits.

关键词： Diabetes Mellitus Gut dysbiosis Oxidative stress Probiotics Limosilactobacillus fermentum

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Ferric carboxymaltose for anemia in Crohn’s disease patients at a tertiary center:A retrospective observational cohort study

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World Journal of Clinical Cases 2023年第12期11卷 2740-2752页

作者： Natália Souza Nunes Siqueira Livia Bitencourt Pascoal Bruno Lima rodrigues Marina Moreira de Castro Alan Sidnei Corrêa Martins Dante Orsetti Silva Araújo luis Eduardo Miani Gomes Michel Gardere Camargo Maria de Lourdes Setsuko Ayrizono Raquel Franco Leal Inflammatory Bowel Disease Research Laboratory GastrocenterColorectal Surgery UnitSchool of Medical SciencesUniversity of Campinas(Unicamp)Campinas 13083-878São PauloBrazil

BACKGROUND Although the gastrointestinal tract is the most affected by Crohn’s disease(CD),the condition triggers other consequent manifestations,and iron deficiency anemia(IDA)is one of the most ***(IV)iron replacement is currently available through several drugs,such as ferric hydroxide sucrose and ferric carboxymaltose(FCM).However,the clinical management of these conditions can be *** To elucidate the drug’s effectiveness,the present study analyzed,through medical records,the clinical and epidemiological data of a cohort of patients with active CD who received IV FCM for the IDA *** This retrospective observational study included 25 patients with active CD,severe anemia,and refractory to previous conventional *** were evaluated two times:During the last treatment with ferric hydroxide sucrose and treatment with *** After treatment with FCM,parameters of IDA assessment significantly improved,serum hemoglobin(Hb)levels increased in 93%of patients(P<0.0001),and in 44%,there was an increase of≥2 g/dL in a single *** addition,86%of the patients showed an increase in serum iron(P<0.0001)and ferritin(P=0.0008)and 50%in transferrin saturation(P=0.01).The serum iron levels at baseline showed a negative association with the ileal and colonic CD and use of biologics and a positive association with patients who developed CD later in life after the age of 40(A3)and with a stenosing(B2)and fistulizing(B3)*** values of Hb and hematocrit after ferric hydroxide sucrose treatment remained similar to those found before *** This study demonstrated that FCM is an important therapeutic strategy for treating IDA in CD patients,achieving satisfactory results in refractory cases.

关键词： Ferric carboxymaltose Iron deficiency anemia Crohn’s disease Inflammatory bowel disease Anemia Clinical management

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