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The Use of Data Mining Techniques in Rockburst Risk Assessment

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Engineering 2017年第4期3卷 552-558页

作者： luis Ribeiro e Sousa Tiago Miranda Rita leal.e Sousa Joaquim Tinoco State Key Laboratory for GeoMechanics and Deep Underground Engineering China University of Mining and Technology (Beijing) Beijing 100083 China Institute for Sustainability and Innovation in Structural Engineering Department of Civil Engineering University of Minho Campus de Azurem Guimaraes 4800-058 Portugal Masdar Institute of Science and Technology Musdar City Abu Dhabi UAE

Rockburst is an important phenomenon that has affected many deep underground mines around the world. An understanding of this phenomenon is relevant to the management of such events, which can lead to saving both costs and lives. Laboratory experiments are one way to obtain a deeper and better understanding of the mechanisms of rockburst. In a previous study by these authors, a database of rockburst laboratory tests was created; in addition, with the use of data mining （DM） techniques, models to predict rockburst maximum stress and rockburst risk indexes were developed. In this paper, we focus on the analysis of a database of in situ cases of rockburst in order to build influence diagrams, list the factors that interact in the occurrence of rockburst, and understand the relationships between these factors. The in situ rockburst database was further analyzed using different DM techniques ranging from artificial neural networks （ANNs） to naive Bayesian classifiers. The aim was to predict the type of rockburst-that is, the rockburst level-based on geologic and construction characteristics of the mine or tunnel. Conclusions are drawn at the end of the paper.

关键词： Rockburst Data mining Bayesian networks In situ database

Correlation between Intestinal Health and Coccidiosis Prevalence in Broilers during Different Seasons of the Year in Brazil from 2012 to 2018

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Food and Nutrition Sciences 2024年第3期15卷 179-198页

作者： Fabio luis Gazoni Gabriela Miotto Galli Marcel Manente Boiago Lenita Moura Stefani Aline Zampar Marco A. Juárez-Estrada Guillermo Tellez-Isaias Aleksandro S. da Silva Animal Health and Reproduction Veterinary Medicine Graduate Program Federal University of Santa Maria (UFSM) Santa Maria Brazil Animal Science Graduate Program Federal University of Rio Grande do Sul (UFRGS) Porto Alegre Brazil Animal Science Graduate Program Santa Catarina State University (UDESC) Chapecó Brazil Departamento de Medicina y Zootecnia de Aves Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Autonoma de Mexico Ciudad Universitaria Ciudad de Mexico Mexico Department of Poultry Science Division of Agriculture University of Arkansas Fayetteville AR USA

Coccidiosis is a disease caused by intracellular protozoan parasites, specifically belonging to the genus Eimeria. These parasites target the gastrointestinal tract in different types of hosts, causing sores in the intestinal lining. The presence of these lesions reduces the animal’s ability to digest and absorb nutrients, significantly impacting their overall performance. The current study aimed to explore the potential correlation between seasonal variations and the incidence of Eimeria spp-induced lesions in broiler chickens’ gastrointestinal tracts in Brazil from 2012 to 2018. A total of 8,607 broiler chickens, aged 14 to 42 days, were sampled from 103 poultry integrated companies in Brazil to conduct intestinal health examinations. The sampling process involved selecting 3 to 6 chickens from each poultry house for examination. The assessment included various abnormalities such as shedding of intestinal cells and excessive fluid and mucus presence, thickening and tension of the intestines, food movement, roughened mucosal surface resembling a Turkish towel in the small intestine, tissue death, duodenal inflammation, intestinal inflammation, gizzard erosion, presence of worms and bedding material, and ingestion of mealworms. During the seasons, winter exhibited the highest average occurrence of Eimeria maxima microorganisms at 52.83%, with E. acervulina following closely at 26.42% in second place. In spring, E. maxima had an occurrence of 11.31%, while in fall, E. tenella had the lowest occurrence at 6.74%. When analyzing the seasonal occurrence of Eimeria, it was observed that E. maxima micro was more common during winter compared to summer (P = 0.0491). However, no discernible variation was observed in the occurrence of the remaining species across different seasons. Research findings suggest that subclinical coccidiosis is most prevalent during the winter season in Brazil. Likewise, clinical disease caused by E. acervulina is also prevalent during this time. I

关键词： Eimeria Epidemiology Intestinal Pathology Broiler Chickens Brazil

Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology and behavioral deficits in parkinsonian rats withα-synucleinopathy

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Neural Regeneration Research 2024年第9期19卷 2057-2067页

作者： Bismark Gatica-Garcia Michael J.Bannon Irma Alicia Martínez-Dávila luis O.Soto-Rojas David Reyes-Corona Lourdes Escobedo Minerva Maldonado-Berny ME Gutierrez-Castillo Armando J.Espadas-Alvarez Manuel A.Fernandez-Parrilla Juan U.Mascotte-Cruz CP Rodríguez-Oviedo Irais E.Valenzuela-Arzeta Claudia Luna-Herrera Francisco E.Lopez-Salas Jaime Santoyo-Salazar Daniel Martinez-Fong Departamento de Fisiología Biofísica y NeurocienciasCentro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico Department of Pharmacology Wayne State University School of MedicineDetroitMIUSA Laboratorio de Patogénesis Molecular Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Red de Medicina para la Educación y Desarrollo y la Investigación Científica de Iztacala(Red MEDICI) Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Nanoparticle Therapy Institute AguascalientesMéxico Departamento de Biociencias e Ingeniería Centro Interdisciplinario de Investigaciones y Estudios sobre Medio Ambiente y DesarrolloInstituto Politécnico NacionalCiudad de MéxicoMéxico Escuela Nacional de Medicina y Homeopatía Instituto Politécnico NacionalCiudad de MéxicoMéxico Departamento de Fisiología Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalCiudad de MéxicoMéxico Departamento de Biología Molecular y Biotecnología Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoCiudad de MéxicoMéxico Departamento de Física Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico Programa de Nanociencias y Nanotecnología Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico

Parkinsonism by unilateral,intranigralβ-sitosterolβ-D-glucoside administration in rats is distinguished in that theα-synuclein insult begins unilaterally but spreads bilaterally and increases in severity over time,thus replicating several clinical features of Parkinson’s disease,a typicalα-*** Nurr1 repressesα-synuclein,we evaluated whether unilateral transfected of rNurr1-V5 transgene via neurotensin-polyplex to the substantia nigra on day 30 after unilateralβ-sitosterolβ-D-glucoside lesion could affect bilateral neuropathology and sensorimotor deficits on day 30 *** study found that rNurr1-V5 expression but not that of the green fluorescent protein(the negative control)reducedβ-sitosterolβ-D-glucoside-induced ***,a bilateral increase in tyrosine hydroxylase-positive cells and arborization occurred in the substantia nigra and increased tyrosine hydroxylase-positive ramifications in the *** addition,tyrosine hydroxylase-positive cells displayed less senescence markerβ-galactosidase and more neuron-cytoskeleton markerβIII-tubulin and brain-derived neurotrophic factor.A significant decrease in activated microglia(positive to ionized calcium-binding adaptor molecule 1)and neurotoxic astrocytes(positive to glial fibrillary acidic protein and complement component 3)and increased neurotrophic astrocytes(positive to glial fibrillary acidic protein and S100 calcium-binding protein A10)also occurred in the substantia *** effects followed the bilateral reduction inα-synuclein aggregates in the nigrostriatal system,improving sensorimotor *** results show that unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neurodegeneration(senescence and loss of neuron-cytoskeleton and tyrosine hydroxylase-positive cells),neuroinflammation(activated microglia,neurotoxic astrocytes),α-synuclein aggregation,and sensorimotor *** neurotrophic astrocytes and

关键词： A1 astrocytes A2 astrocytes gene therapy microglia motor deficits nanoparticles neurodegeneration neuroinflammation senescence α-synuclein aggregates

Concordance among pulse wave velocity assessment methods: A network meta-analysis

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中华医学杂志(英文版) 2024年第17期137卷 2024 Aug 8页

作者： Cavero-Redondo Iván Sequí-Domínguez Irene Saz-Lara Alicia Garcia-Klepzig Jose luis Lucerón-Lucas-Torres Maribel Martínez-García Irene álvarez-Bueno Celia Martínez-Vizcaíno Vicente CarVasCare Research Group Facultad de Enfermería de Cuenca Universidad de Castilla-La Mancha Cuenca Spain Facultad de Ciencias de la Salud Universidad Autónoma de Chile Talca Chile Health and Social Research Center Universidad de Castilla-La Mancha Cuenca Spain Internal Medicine Department San Carlos University Hospital Madrid Spain Universidad Politécnica y Artística del Paraguay Asunción Paraguay

DNA repair deficiency in neuropathogenesis:when all roads lead to mitochondria

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Translational Neurodegeneration 2019年第1期8卷 157-170页

作者： luis Bermúdez-Guzmán Alejandro leal Section of Genetics and Biotechnology School of BiologyUniversidad de Costa RicaSan José11501Costa Rica Neuroscience Research Center Universidad de Costa RicaSan JoséCosta Rica

Mutations in DNA repair enzymes can cause two neurological clinical manifestations:a developmental impairment and a degenerative *** kinase 3′-phosphatase(PNKP)is an enzyme that is actively involved in DNA repair in both single and double strand break repair *** in this protein or others in the same pathway are responsible for a complex group of diseases with a broad clinical ***,mitochondrial dysfunction also has been consolidated as a hallmark of brain *** we provide evidence that supports a shared role between mitochondrial dysfunction and DNA repair defects in the pathogenesis of the nervous *** models,we analyze PNKP-related disorders,focusing on Charcot-Marie-Tooth disease and ataxia.A better understanding of the molecular dynamics of this relationship could provide improved diagnosis and treatment for neurological diseases.

关键词： DNA repair Mitochondrial dysfunction Neurodegeneration Ataxia PNKP

A Pilot Test for A One-year Cognitive Training Intervention in Elderly Adults with Mild Cognitive Impairment

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Biomedical and Environmental Sciences 2020年第10期33卷 796-802页

作者： MENDOZA-HOLGADO Cristina LOPEZ-ESPUELA Fidel MORAN Jose Maria RONCERO-MARTIN Raul LAVADO-GARCIA Jesus ALIAGA Ignacio PUERTO-PAREJO luis Manuel leal.HERNANDEZ Olga VERA Vicente PEDRERA-CANAL Maria Nursing Department Metabolic Bone Disease Research GroupUniversity of ExtremaduraNursing and Occupational Therapy CollegueAvd.Universidad s/n10003-CaceresSpain Facultad de Odontologia Universidad ComplutenseMadridSpain

In Spain,the proportion of elderly individuals has increased to 19.1%.By 2068,the proportion of elderly individuals is estimated to increase to 29.4% given the largest birth cohorts in Spain’s history(Instituto Nacional de Estadistica,INE).This challenge needs a supportive plan,as economic and caring problems may occur because of age-related health problems,including cognitive decline and dementia[1].

关键词： elderly Pilot Training

New frontiers on open standards for geo-spatial science

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Geo-Spatial Information Science 2017年第2期20卷 126-133页

作者： luis Bermudez Open Geospatial Consortium WaylandMAUSA

The process of sharing of data has become easier than ever with the advancement of cloud computing and software ***,big challenges remain such as efficient handling of big geospatial data,supporting and sharing of crowd sourced/citizen science data,integration with semantic heterogeneity,and inclusion of agile processes for continuous improvement of geospatial *** paper discusses the new frontiers regarding these challenges and the related work performed by the Open Geospatial Consortium,the world leading organization focused on developing open geospatial standards that“geo-enable”the Web,wireless,and location-based services and mainstream IT.

关键词： Open Geospatial Consortium(OGC) big data cloud computing open standards semantics linked data

Risk Factors Associated with Unsuccessful Vaginal Birth after One Cesarean (VBAC-1) in Puerto Rico

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Open Journal of Obstetrics and Gynecology 2024年第6期14卷 888-902页

作者： Irazú Guinan Marjorie Suárez Fabiola Angulo luis Mayol Paula Suárez Lisandris Dominicci Nathalie Chang Saribel Torres Antonio Rodríguez Raymond L. Tremblay Maricarmen Colón-Díaz Department of Physiology and Pathology San Juan Bautista School of Medicine Caguas USA

Background: Cesarean section (CS) has increased steadily over the last decade, with an estimated one-third of women delivering by cesarean section worldwide. Objective: Our study aimed to investigate the demographic and associated factors influencing vaginal birth after one cesarean (VBAC-1) success focusing on variables like pre-pregnancy BMI, diabetes, hypertension, education, and smoking. Study Design and Methods: In this retrospective study, we analyzed 285 cases (81 unsuccessful VBAC-1, 204 successful VBAC-1) from San Juan City Hospital (Puerto Rico) between January 1, 2019, and December 31, 2020. We used odds ratios and model selection comparison to assess the impact of variables on successful VBAC-1, using a significance threshold of 95% CI. Model selection assessed binomial model combinations using a generalized linear approach to identify key risk factors. Results: Unsuccessful VBAC-1 (a repeat cesarean), was associated with diabetes (OR: 0.376, p = 0.086), hypertension (OR: 0.23, p = 0.006), and university-educated women (OR: 1.372, p = 0.711). High school-educated women had an OR of 3.966 (p = 0.105), while overweight women were 0.481 times more likely to have unsuccessful VBAC-1 (p = 0.041). Significant associations were not found with obesity (OR: 0.574, p = 0.122), underweight/normal (OR: 1.01, p = 0.810), or smoking (OR: 1.227, p = 0.990). Conclusion: Results revealed women with higher education levels, hypertension, or diabetes are less likely to have a successful VBAC-1. Understanding the complex interactions affecting these outcomes is aimed at establishing guidelines for healthcare professionals to conduct systematic risk/benefit assessments. This study lays a foundation for evidence-based practices and policies, offering initial insights into VBAC-1 success factors in Puerto Rico.

关键词： Diabetes Hypertension Obesity Trial of Labor Vaginal Birth after Cesarean

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考古植物遗存中的碳稳定同位素

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东方考古 2024年第1期 146-179页

作者： Juan Pedro Ferrio Mònica Aguilera Jordi Voltas José luis Araus 褚黎明阿拉贡研究与发展机构(ARAID) 阿拉贡农业研究与技术中心(CITA)森林资源部 CTFC-AGROTECNIO联合研究单位莱里达大学农作物与森林科学系巴塞罗那大学生物学院植物生理学部综合作物生理生态学组农业技术研究中心(AGROTECNIO) 山东大学文化遗产研究院

考古植物遗存是了解关于过去社会经历的社会和环境条件的宝贵信息来源。植物遗存巨大潜力的充分开发需要分析技术的应用。在这一背景下,考古植物遗存的碳稳定同位素组成或许能够提供关于环境条件、农业管理、食物网和饮食偏好等多方面... 详细信息

考古植物遗存是了解关于过去社会经历的社会和环境条件的宝贵信息来源。植物遗存巨大潜力的充分开发需要分析技术的应用。在这一背景下,考古植物遗存的碳稳定同位素组成或许能够提供关于环境条件、农业管理、食物网和饮食偏好等多方面的线索。本文全面介绍了分析植物遗存的碳稳定同位素在考古学中的潜在应用。在对决定植物碳稳定同位素特性的广泛生理和环境因素进行解释之后,对最相关的方法问题进行了讨论。其中,本文对样品的前处理方式、与大气变化有关的不确定性以及植物遗存在土壤中沉积前后经历的潜在变化进行了评述。以选定的案例研究为例,为碳稳定同位素在考古学中的应用提供了方法和概念上的线索。同时,也强调了依旧存在的挑战。

关键词：碳稳定同位素植物考古环境农业