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Role of the HLA-DQ locus in the development of chronic gastritis and gastric carcinoma in Mexican patients

World Journal of Gastroenterology 2006年第48期12卷 7762-7767页

作者： Roberto Herrera-Goepfert Jesús K Yamamoto-furusho luis f oate-ocaa Margarita Camorlinga-Ponce Leopoldo Muoz Jorge A Ruiz-Morales Gilberto Vargas-Alarcón Julio Granados Cellular Biology Section Department of Pathology Institute Nacional de Cancerologia (INCan) Mexico City Mexico Department of Immunology and Rheumatology Institute Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Mexico City Mexico Department of Gastroenterology Institute Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Mexico City Mexico Department of Gastroenterology (INCan) Mexico City Mexico Medical Research Unit on Infectious and Parasitic Diseases Hospital de Pediatria Centro Medico Nacional Siglo XXI (CMN-SXXI) Institute Mexicano del Seguro Social (IMSS) Mexico City Mexico Department of Immunology and Rheumatology Institute Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Mexico City Mexico Department of Physiology Institute Nacional de Cardiologia Ignacio Chavez Mexico City Mexico

AIM： To determine the HLA-DQ locus in Mexican patients with Chronic gastritis and gastric adenocarcinoma.METHoDS： oligotyping for HLA-DQ locus was performed in 45 Mexican patients with chronic gastritis and 13 Mexican patients with diffuse-type gastric adenocarcinoma, and was then compared with 99 clinically healthy unrelated individuals. H pylori infection and CagA status were assessed in patients by enzyme-linked immunosorbent assay （EUSA） method. RESULTS： We found a significant increased frequency of HLA-DQBI＊0401 allele in Hpylori-positive patients with chronic gastritis when compared with healthy subjects [19 vs 0%, P = 1 × 10^-7, odds ratio （oR） = 4.96; 95% confidence interval （95% CI）, 3.87-6.35]. We also found a significant increased frequency of HLA-DQBI＊0501 in patients with diffuse-type gastric carcinoma in comparison with healthy individuals （P = 1 × 10^4, oR = 13.07; 95% CI, 2.82-85.14）.CoNCLUSIoN： HLA-DQ locus may play a different role in the development of H pylori-related chronic gastritis and difffuse-type gastric adenocarcinoma in the Mexican Mestizo population.

关键词： HLA-DQ HLA-DQ5 HLA-DQBI*0501 Hpy/or/ Chronic gastritis Gastric cancer Diffuse-type adenocarcinoma

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Introduction to the special issue on “CoVID-19”

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Geoscience frontiers 2022年第6期13卷 208-209页

作者： luis f.o.Silva Weijun Li Teresa Moreno Department of Civil and Environmental Universidad de la CostaCUC Department of Atmospheric Sciences School of Earth SciencesZhejiang University Institute for Environmental Assessment and Water Research Consejo Superior de Investigaciones Científicas

CoVID-19 pandemic is wreaking havoc and bringing the whole world into a standstill in an unprecedented fashion. Joint efforts from multiple sectors to address the various aspects of environment and public health through usage of green technologies have become essential. The application of cleaner and effective technologies can be expanded to management and control, pollution mitigation and valorization of waste. In this Special Issue of Geoscience frontiers, we present contributions addressing the interactions of CoVID-19 in relation to environment and human health.

关键词： bringing expanded CoV

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Comparative carbon emission assessments of recycled and natural aggregate concrete: Environmental influence of cement content

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Geoscience frontiers 2021年第6期12卷 66-75页

作者： Marian Sabǎu Dan V.Bompa luis f.o.Silva Department of Civil and Environmental Engineering Universidad de la Costa080020 BarranquillaColombia Department of Civil and Environmental Engineering University of SurreyGuildford GU27XHUK Departamento de Ingeniería Civil y Arquitectura Universidad de LimaAvenida Javier Prado Este 4600Santiago de Surco 1503Peru

This work examines the environmental and geochemical impact of recycled aggregate concrete production with properties representative for structural *** environmental influence of cement content,aggregate production,transportation,and waste landfilling is analysed by undertaking a life cycle assessment and considering a life cycle inventory largely specific for the *** obtain a detailed insight into the optimum life cycle parameters,a sensitivity study is carried out in which supplementary cementitious materials,different values of natural-to-recycled aggregate content ratio and case-specific transportation distances were *** results show that carbon emissions were between 323 and 332 kgCo_(2)e per cubic metre of cement only natural aggregate *** values can be reduced by up to 17%by replacing 25%of the cement with fly *** contrast,carbon emissions can increase when natural coarse aggregates are replaced by recycled aggregates in proportions of 50%and 100%,and transportation is not included in ***,the concrete with 50%recycled aggregate presented lower increase,only 0.3%and 3.4%for normal and high strength concrete,*** some cases,the relative contribution of transportation to the total carbon emissions increased when cement was replaced by fly ash in proportions of 25%,and case-specific transportation distances were *** absolute values,the concrete mixes with 100%recycled aggregates and 25%fly ash had lower carbon emissions than concrete with cement and natural aggregates *** environmental benefits can be obtained when the transportation distances of fly ash are relatively short(15–25 km)and the cement replacement by fly ash is equal or higher than 25%,considering that the mechanical properties are adequate for practical *** observations from this paper show that recycled aggregate concrete with strength characteristics representative for structural members can have lowe

关键词： Life cycle assessment Recycled aggregate Natural aggregate Transportation distance openLCA

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Environmental geochemistry:Introduction

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Geoscience frontiers 2022年第1期13卷 374-375页

作者： luis f.o.Silva Marcos L.S.oliveira Department of Civil and Environmental.Universidad de la Costa CUCCalle 58#55-66BarranquillaAtlánticoColombia Departamento de Ingeniería Civil y Arquitectura Universidad de LimaAvenida Javier Prado Este 4600Santiago de Surco 1503Peru

Assessing the physical,geographic,chemical,and geological aspects are important to understand environmental impacts as well as health concerns in view of building a more sustainable planet with circular economies that would last for the foreseeable *** the recent years,the significance of incorporating ecosystem,anthropogenic activities,and climate has fortified from being an academic concern(e.g.,WEf,2011)into a broadly societal concern as the forecasted realities of environmental deterioration and global climate change come to pass.

关键词： geochemistry climate planet

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An analysis of vehicular exhaust derived nanoparticles and historical Belgium fortress building interfaces

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Geoscience frontiers 2020年第6期11卷 2053-2060页

作者： luis f.o.Silva Diana Pinto Alcindo Neckel Marcos L.S.oliveira Department of Civil and Environmental Engineering.Universidad de La Costa CUCCalle 58#55-66BarranquillaAtlanticoColombia faculdade Meridional IMED 304-Passo FundoRS 99070-220Brazil University of Antwerp Prinsstraat 132000AntwerpBelgium

Air pollution monitoring is one of the most important features in contamination risk *** is because many of the compounds contained within air pollution present a serious risk both for the preservation of open air cultural heritage and for human *** particle formation is a major contributor to urban pollution,but how it occurs in cities is often *** more and more people enjoy an increased quality of life through outdoor activity,managing outdoor air quality is *** study presents the application of a low-cost system for monitoring the current level of road traffic passengers’exposure to particulate air *** global rise in tourism also leads to apprehension about its probable destructive influence on various aspects of global *** of the major risks encountered by tourists,stemming from modes of transport,are nanoparticles(NPs)(fine particles(UfPs)(100-1000 nm)consisting of potentially hazardous elements(PHEs).This study examines Steen Castle,a medieval fortress located in Antwerp,*** NPs with PHEs,were found in the air sampled in this *** self-made passive sampler(LSPS)described in this study,consisting of retainers specially designed for advanced microscopic analysis,is used for the first time as a simple way to characterize the surrounding atmospheric contamination caused by NPs and UfPs,without the need of other commonly employed more expensive particulate focused active samplers such as cascade *** study aims to assess the result of the utilization of a low-cost,LSPS,to determine outdoor NPs and UfPs in a Belgian urban(Steen Castle)and rural area(fort van Schoten).This work is the first to detail the usefulness of LSPS for the evaluation of Belgium’s outdoor air for NPs and UfPs,which contain PHEs.

关键词： Atmospheric contamination Historic construction Carbonaceous particles Source investigation Vehicular traffic effects

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Nanomineralogy of evaporative precipitation of efflorescent compounds from coal mine drainage

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Geoscience frontiers 2021年第6期12卷 404-410页

作者： luis f.o.Silva Diana Pinto Guilherme L.Dotto James C.Hower Department of Civil and Environmental.Universidad de La Costa CUCCalle 58#55–66BarranquillaAtlanticoColombia Universidade federal de Santa Maria–UfSM 1000Roraima Avenue97105–900Santa MariaRSBrazil University of Kentucky Department of Earth&Environmental SciencesLexingtonKY40506USA University of Kentucky Center for Applied Energy Research2540 Research Park DriveLexingtonKY40511USA

Efflorescent nanophases(NPs) are found as a transitory accumulation of potentially hazardous elements(PHEs),particularly in tropical climates. The central objective of this study was to investigate the distribution of PHEs with NPs through the evaporative formation structures(EfS) of enormously PHEs-rich coal-mine drainages(CMD). The EfS were studied in natural coal mine drainage for five months in order to determine their geochemical and ecological structures and to assess their position in the reduction of PHEs in nature. The largest coal-fired power plant in South America, located in south Brazil, is used as an example of such a problem. In this work, a novel methodology for the analysis of PHEs in CMD precipitates is proposed for this affected coal *** analytical method, combining X-Ray Diffraction(XRD) and advanced electron microscopies, shows the importance of nanomineralogy in understanding different circumstances of coal contamination. Several ultrafinenanoparticles(UNPs) were identified in the sampled soils and river sediments together with the PHEs. A decrease in PHEs was identified in association with UNPs. However, further investigations are required with regard to the mobility of PHEs in water, atmosphere, soils, and sediments. The EPS was thoroughly studied, acquiring suitable understanding with investigational facts for Ca and fe-sulphates, pickeringite, and several amorphous phases.

关键词： Coal mine drainage Evaporative precipitation Sediments Water and soil pollution

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Coal energy and environmental impacts:Introduction

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Energy Geoscience 2021年第2期2卷 87-89页

作者： luis f.o.Silva Amy L.Wolfe Department of Civil and Environmental.Universidad de La Costa CUCCalle 58#55e66BarranquillaAtlanticoColombia Kentucky Geological Survey University of Kentucky216 Mining and Mineral Resources Building504 Rose StreetLexingtonKY40506-0107USA

Within the last decade,the importance of integrating the envi-ronment,people,and climate has transitioned from being an aca-demic concern(e.g..WEf,2011)into a broadly societal concern asthe forecasted realities of environmental deterioration and globalclimate change come to pass,creating urgent public and environ-mental health issues.

关键词： has integrating environ

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Ambient nanoparticles/nanominerals and hazardous elements from coal combustion activity:Implications on energy challenges and health hazards

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Geoscience frontiers 2018年第3期9卷 863-875页

作者： Binoy K.Saikia Jyotilima Saikia Shahadev Rabha luis f.o.Silva Robert finkelman Polymer Petroleum and Coal Chemistry Group Materials Science and Technology DivisionCSIR-North East Institute of Science and TechnologyJorhat785006AssamIndia Academy of Scientific and Innovative Research CSIR-NEIST CampusJorhat785006India Research group in Environmental Management and Sustainability Department of Civil and Environmental EngineeringUniversidad de la CostaBarranquillaColombia University of Texas at Dallas RichardsonTXUSA

Coal is the most abundant fossil fuel in the world. Because of the growth of coal mining, coal-fired power plants and coal-burning industries, the increase of the emission of particulates(coarse, fine or ultrafine)is of great concern. There is a relationship between increasing human morbidity and mortality and progressive environmental air pollution caused by these types of particles. Thus, the knowledge of the physico-chemical composition and ambient concentrations of coal-derived nanoparticles will improve pollution control strategy. Given the current importance of this area of research, the advanced characterization of this coal combustion-derived nanoparticles/nanominerals as well as hazardous elements is likely to be one of the hottest research fields in coming days. In this review, we try to compile the existing knowledge on coal-derived nanoparticles/nanominerals and discuss the advanced level of characterization techniques for future research. This review also provides some of aspects of health risks associated with exposure to ambient nanoparticles. In addition, the presence of some of the hazardous elements in coal and coal combustion activities is also reviewed.

关键词： Coal combustion Nanoparticles Nanominerals Hazardous elements Human health Coal energy challenge

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Progress and challenges in the comprehensive management of chronic viral hepatitis: Key ways to achieve the elimination

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World Journal of Gastroenterology 2021年第26期27卷 4004-4017页

作者： fátima Higuera-de la Tijera Alfredo Servín-Caamaño luis Servín-Abad Department of Gastroenterology and Hepatology Hospital General de MéxicoMexico City 06726Mexico Department of Internal Medicine Hospital General de MéxicoMexico City 06726Mexico Department of Gastroenterology Saint Cloud HospitalSaint CloudMN 56303United States

Chronic viral hepatitis is a significant health problem throughout the world,which already represents high annual *** 2040,chronic viral hepatitis due to virus B and virus C and their complications cirrhosis and hepatocellular carcinoma will be more deadly than malaria,vitellogenesis-inhibiting hormone,and tuberculosis *** this review,we analyze the global impact of chronic viral hepatitis with a focus on the most vulnerable groups,the goals set by the World Health organization for the year 2030,and the key points to achieve them,such as timely access to antiviral treatment of direct-acting antiviral,which represents the key to achieving hepatitis C virus ***,we review the strategies to prevent transmission and achieve control of hepatitis B ***,we address the impact that the coronavirus disease 2019 pandemic has had on implementing elimination strategies and the advantages of implementing telemedicine programs.

关键词： Hepatitis C Hepatitis B Vaccination Elimination program Telemedicine Direct antiviral agents

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flowback and early-time production modeling of unconventional gas wells using an improved semi-analytical method

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Petroleum Science 2023年第6期20卷 3441-3449页

作者： Miao Zhang Kien Nguyen Zhi-Qiang Wang luis f.Ayala College of Petroleum Engineering China University of PetroleumBeijing102249China University of Tulsa USA The Pennsylvania State University USA

Multiple fractured horizontal wells (MfHWs) currently are the only possible means of commercial production from the low and ultra-low permeability unconventional gas reservoirs. In early production time, flowback fluid, which constitutes of hydraulic water and gas flow within fractures, is collected and analyzed. flowback analysis has been shown to be a useful tool to estimate key properties of the hydraulic fracture such as conductivity and pore volume. Until date, most tools of flowback analysis rely on empirical and approximate methods. This study presents an improved Green-function-based semi-analytical solution for performance analysis of horizontal gas wells during flowback and early production periods. The proposed solution is derived based on coupling the solutions of two domains: a rigorously derived Green’s function-based integral solution for single-phase gas flow in matrix, and a finite-difference, multiphase solution for gas–water two-phase flow in the fracture. The validity of proposed semi-analytical solution is verified by finely gridded numerical models built in a commercial simulator for a series of synthetic cases considering a variety of fluid and reservoir property combinations, as well as various different production constraints. Comparisons against available empirical and approximate methods are also provided for these cases.

关键词： Hydraulic fractures flowback Unconventional gas wells

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